Abstract: The invention relates to a method of separating biological particles from the liquid containing same for purification, analysis and optionally diagnostic purposes. The inventive method comprises at least one step involving vertical filtration through a filter having a porosity that is adapted to the type of biological particles to be separated, such that said particles are retained by the filter. The invention is characterised in that: (i) the method involves the use of a filter comprising at least one basic filtration zone, whereby each basic filtration zone has a limited surface area; and (ii) the surface area of each basic filtration zone and the number of basic filtration zones are selected as a function of the type of liquid to be filtered, the type of biological particles to be separated and the volume of liquid to be filtered.

Abstract: The invention relates to a method of separating biological particles from the liquid containing same for purification, analysis and optionally diagnostic purposes. The inventive method comprises at least one step involving vertical filtration through a filter having a porosity that is adapted to the type of biological particles to be separated, such that said particles are retained by the filter. The invention is characterised in that: (i) the method involves the use of a filter comprising at least one basic filtration zone, whereby each basic filtration zone has a limited surface area; and (ii) the surface area of each basic filtration zone and the number of basic filtration zones are selected as a function of the type of liquid to be filtered, the type of biological particles to be separated and the volume of liquid to be filtered.

Abstract: The invention relates to a method of separating biological particles from the liquid containing same for purification, analysis and optionally diagnostic purposes. The inventive method comprises at least one step involving vertical filtration through a filter having a porosity that is adapted to the type of biological particles to be separated, such that said particles are retained by the filter. The invention is characterized in that: (i) the method involves the use of a filter comprising at least one basic filtration zone, whereby each basic filtration zone has a limited surface area; and (ii) the surface area of each basic filtration zone and the number of basic filtration zones are selected as a function of the type of liquid to be filtered, the type of biological particles to be separated and the volume of liquid to be filtered.

Abstract: The invention relates to the use of gingival fibroblasts for obtaining a cellular composition for treating arterial-remodelling pathology, for example an aneurysm, post-cryoplasty stenosis and restenosis, an aortic dissection or atherosclerosis.

Abstract: The present invention relates to a gingival fibroblast culture medium free of animal serum, comprising an animal cell culture medium, free of animal serum, to which is added: from 0.1 ng/ml to 100 ng/ml bFGF, and/or from 1 ?g/ml to 50 ?g/ml insulin.

Abstract: An in vitro method for determining whether a patient infected with HCV is a responder or non-responder to the treatment with interferon-alpha and ribavirin. More specifically, the method includes a step of determining the expression level of the IFI27, CXCL9 and G1P2 genes in a biological sample.

Abstract: The present invention relates to a method for treating a skin wound in an individual, comprising applying to the skin wound of the individual a therapeutically effective quantity of gingival fibroblasts.

Abstract: The invention relates to a non-invasive, prenatal, in-vitro method for detecting the normal healthy condition, the condition of a healthy carrier or the condition of a carrier inflicted with cystic fibrosis, from the fetal cell(s) from a maternal sample, comprising the DNA of an individual to be tested. The invention also relates to oligonucleotide primers and to their use within the scope of a non-invasive, prenatal, in-vitro method for detecting the condition of a healthy carrier or of a carrier inflicted with cystic fibrosis.

Abstract: The present invention relates to the use of a nucleic acid encoding a chimeric transfer RNA (tRNA), which chimeric tRNA originates from the modification of a tRNA by insertion of an RNA into the stem-loop of the anticodon of the tRNA and/or by substitution of all or part of the stem-loop of the anticodon of the tRNA with an RNA, for the production of the RNA or of a part of the RNA, in a cell.

Abstract: The present invention relates to polynucleotides enabling the rapid, simple and specific detection of Group B Streptococcus highly-virulent ST-17 clones. The present invention also relates to the polypeptides encoded by said polynucleotides, as well as to antibodies directed or raised against said polypeptides. The present invention also relates to kits and methods for the specific detection of Group B Streptococcus highly-virulent ST-17 clones, using the polynucleotides, the polypeptides or the antibodies according to the invention.

Abstract: The invention concerns the use of Mangafodipir to obtain a medicine for preventive or curative treatment of hepatocellular deficiencies.

Abstract: The invention relates to the use of superoxide dismutase mimetics and reductase glutathione (preferably Mangafodipir) in order to produce an anticancer drug. Said mimetic, in particular makes it possible to potentiate the actions of antitumoral agents generating active oxygen forms on tumoral cells and to protect non-tumoral cells against said actions.

Abstract: To treat hydrocephaly, an intracranial catheter is implanted in the head. It is connected to a tube fitted with a non-return valve and serves to divert the flow of cephalo-rachidian liquid to the peritoneum or to the right auricle of the heart. In accordance with the invention a hydraulic filter of non-linear variable impedance is connected in the tube in series with the valve. The filter maintains an average flow rate of the cephalo-rachidian liquid close to the physiological flow rate, but prevents sudden rushes of fluid flow, thereby permitting the intracranial pressure to vary in the short term in the normal manner over a characteristic period of about one second, while preventing said pressure from rising slowly in the long term, e.g. over a characteristic period of about one minute. This is done by a bead (160) which is housed in a cavity (161) extending between a proximal orifice (111) and a distal orifice (136). The distal orifice constitutes a leaky valve seat for the bead.

Abstract: A probe for studying the visco-elastic behavior of sphincters of living organisms is comprised of an expansible head formed by three articulated groups disposed radially at 120.degree. intervals about a central axis. Each of the articulated groups is composed of a cross-piece which interconnects a rigid member, carrying a strain gauge on its outer surface, to the central axis. The cross-pieces are articulated at one end about the opposite ends of the rigid member and are articulated at the other end about two blocks which are carried by the central axis. The cross-pieces are constructed such that rotation of the central axis causes the distance between the rigid elements and the central axis to vary. A flexible shaft couples the central axis to a motor.