Abstract: The present disclosure provides devices, kits, and methods for focusing/enriching and/or separating/sorting submicron size particles, including biological entities such as exosomes and other submicron size extracellular vesicles. Devices, kits, and methods of the present disclosure utilize ferrohydrodynamic manipulation to focus populations of submicron particles into a stream for enrichment and/or further sort various sub-populations of submicron particles based on size differences.

Abstract: A heat attenuated infectious bronchitis virus (IBV) isolate of PDRC DMV/1639 deposited at the ATCC under Patent Designation PTA-126757 and progeny and derivatives thereof and compositions thereof are presented. Methods for administering the isolates and compositions as vaccines to prevent virulent IBV infection in birds of the order Galliformes are also presented.

Abstract: Methods and compositions disclosed herein generally relate to genes involved in plant reproduction and methods of using the same.

Abstract: Disclosed herein are oligosaccharides and intermediates useful for the production thereof. The compounds are useful as analytical standards and as intermediates for the preparation of more complex oligosaccharide and N-glycan products. The compounds may be prepared in high purity using the selective stop/go synthetic methods disclosed herein.

Abstract: As disclosed herein, stapled peptides targeting the interaction interface between proteins that maintain the integrity of Wiskott-Aldrich syndrome protein family member 3 (WASF3) leads to destabilization of WASF3 and suppression of invasion. Disclosed are stapled peptides that inhibit the binding of Cytoplasmic FMR1-interacting protein 1 (CYFIP1) to either WASF3 or NCK-associated protein (NCKAP1). Also disclosed are methods for treating or suppressing invasion and metastasis of a cancer in a subject that involve administering to the subject a therapeutically effective amount of a stapled peptide disclosed herein.

Abstract: Various examples of a system for peanut sorting and grading are disclosed herein. The system for grading peanut maturity, can include: a sample feeder configured to supply individual peanuts to an imaging area; a sorting board comprising a plurality of chutes and a plurality of gates, each chute of the plurality of chutes designated for a grade of peanut; and program instructions to obtain the digital image of the individual peanut; determine the grade of the individual peanut; and sort the individual peanut based on the grade of the individual peanut. A method for grading peanut maturity, can include feeding an individual peanut to an imaging area; obtaining a digital image of the individual peanut; determining a grade of the individual peanut based on an average color; and sorting the individual peanut in a chute of a sorting board based on the grade of the individual peanut.

Abstract: Provided herein is a protein, referred to as a Pn3Pase protein, that degrades the capsular polysaccharide of serotype 3 Streptococcus pneumoniae. The disclosure includes a genetically modified cell that includes a Pn3Pase protein, and compositions that include the protein, the polynucleotide encoding the protein, the genetically modified cell, or a combination thereof. Also provided are methods for using a Pn3Pase protein, including methods for contacting a S. pneumoniae having a type III capsular polysaccharide with a Pn3Pase protein, increasing deposition of at least one complement component on the surface of a S. pneumoniae, treating an infection in a subject, treating a symptom in a subject, decreasing colonization of a subject by S. pneumoniae, or a combination thereof.

Abstract: The present disclosure includes methods and systems of detecting bacteria in a sample using phage-functionalized sensors, methods of enriching a sample with phage-functionalized magnetic particles, phage-functionalized magnetic particles and methods of making phage-functionalized magnetic particles.

Abstract: Disclosed are compositions and methods for increasing virus production. In particular, disclosed herein are cell or cell line comprises reduced expression of one or more cellular genes selected from the group comprising COQ9, FGF2, NAT9, NDUFA9, NEU2, PLA2G1B, PYCR1, RAD51AP1, STRADA, SVOPL, and/or ZFYVE9 for use in increasing viral production.

Abstract: A variety of devices and methods are provided for separating or enriching circulating tumor cells in a biological sample such as whole blood. In some aspects, the devices are multi-stage devices including at least (i) a filtering stage, (ii) a sheath flow stage for ferrohydrodynamic separation of magnetically labelled white blood cells, and (iii) a focusing stage for marker-independent and size-independent focusing of magnetically labeled particles so as to separate or enrich unlabeled rare cells in the biological sample. The devices and methods are, in some aspects, capable of high throughput in excess of 6 milliliters per hour while achieving high separation (>95%) of the unlabeled rare cells.

Abstract: Provided herein are antibodies and related polypeptides that bind specifically to CEACAM6. The antibodies and/or polypeptides can be configured as bispecific T cell engagers. The antibodies and/or polypeptides can also be configured as chimeric antigen receptors. Also provided are methods of detection and treatment of cancer, for example, pancreatic cancer, using the antibodies and related polypeptides herein.

Abstract: Antibodies and antigen binding fragments that specifically bind to human metapneumovirus (hMPV) F protein and neutralize hMPV are disclosed. Nucleic acids encoding these antibodies, vectors and host cells are also provided. The disclosed antibodies, antigen binding fragments, nucleic acids and vectors can be used, for example, to inhibit an hMPV infection or detect a hMPV infection.

Abstract: A new and distinct cultivar of Bermudagrass hybrid Cynodon transvaalensis x Cynodon dactylon named ‘12-TG-101’ is provided. The new and distinct upright variety is characterized by a combination of superior turfgrass uniformity, very dark green leaf color, and high putting green speeds. The asexually reproduced triploid variety is reliably propagated vegetatively.

Abstract: A new and distinct cultivar of Cupressus plant named ‘RutCup1’, characterized by its wider form and similar heigh and growth rate to Cupressus arizonica var. glabra cultivars; glaucous, blue-green foliage; resistance to Passalora blight; and cold hardiness to about ?30° C. in laboratory tests.

Abstract: A new and distinct cultivar of Ilex plant named ‘RutHol5’, characterized by its upright, narrow form with widest spread in the middle of the canopy that narrows towards the top; a height-to-width ratio of about 3.2; reddish colored new growth, and resistance to spider mites, Tetranychus urticae.

Abstract: A new and distinct cultivar of Thuja plant named ‘RutThu5’, characterized by its nice, columnar form, dark green foliage that does not have chartreuse tips like Thuja occidentalis ‘Emerald Green’. ‘RutThu5’ can be grown with one cutting per pot compared to the industry standard of three cuttings per pot, and has similar growth rate in containers and field as three-cutting plants of ‘Emerald Green’. The new ‘RutThu5’ has demonstrated cold hardiness to about ?34° F. in trials conducted in Minnesota.

Abstract: A new and distinct cultivar of Ilex plant named ‘RutHol7’, characterized by its upright, elliptical growth habit; a height-to-width ratio of about 2.3; grayish-purple new growth, and narrower leaves than similar Ilex cultivars.

Abstract: A new and distinct cultivar of Thuja plant named ‘RutThu3’, characterized by its compact, rounding form and yellow foliage with orange tips; growth and heat tolerance in USDA Zone 8a, growth in full sun and afternoon shade conditions in landscape and full sun in container production, disease and insect resistance, and cold hardiness to about ?34° F. in Minnesota.

Abstract: A new and distinct cultivar of Ilex plant named ‘RutHol6’, characterized by its full, oval growth habit; a height-to-width ratio of about 1.3; grayish-red new growth, and wider leaves than similar Ilex cultivars.

Abstract: A new and distinct cultivar of Thuja plant named ‘RutThu4’, characterized by its compact, globose growth, similar in shape but larger in size and with a faster growth rate than some other Thuja occidentalis cultivars. ‘RutThu4’ also has disease resistance when grown in USDA Zone 8a, and has demonstrated both heat tolerance as well as cold hardiness to about ?34° F. in trials conducted in Minnesota.