Abstract: The present invention relates to a novel family of Technetium chelating agents (ligands) based upon amide and mercaptide donor groups.

Abstract: Ferroelectric (chiral) smectic liquid crystal compounds having an achiral core and chiral tail units derived from lactic acid possess the desired combination of properties temperature range, ferroelectric polarization, and low orientational viscosity. These newly made compounds exhibit high speed, multistate electro-optic switching properties which make them ideally suited to certain electro-optic and display device applications.

Abstract: A new class of nucleoside phosphoramidites which are relatively stable to permit isolation thereof and storage at room temperature. The phosphoramidites are derivatives of saturated secondary amines.

Abstract: Beta double prime alumina is provided having a sensible amount of at least one polyvalent cationic species intercalated therein. In accordance with a preferred embodiment, such beta double prime alumina is provided having trivalent and/or tetravalent cationic species intercalated therein, especially species derived from the lanthanide and actinide series of elements. Certain of the foregoing materials exhibit phosphorescence or fluorescence, and some are believed to be capable of producing laser emission upon suitable irradiation.Methods for modifying beta double prime aluminas comprising contacting crystals of the aluminas with polyvalent cation-containing salts such as in the molten state or in the gaseous state are also provided. Laser and other optical devies are disclosed employing the modified beta double prime aluminas of this invention.

Abstract: Compounds of the formula: ##STR1## wherein R.sub.1 is a moiety selected from the group consisting of ##STR2## R.sub.2 -R.sub.22 are amino acid moieties wherein R.sub.2 is an optional moiety which when present is selected from the group consisting of Ser and Gly,R.sub.8 is Leu or Val,R.sub.10 is Gln, Lys, or Gly,R.sub.11, R.sub.14, and R.sub.20 are each independently selected from the group consisting of Gln and Lys,R.sub.12 is Leu or Trp,R.sub.13 is Gln or Ser,R.sub.17 is Gln or His,R.sub.19 is Leu or Cys,R.sub.21 is Gln or Thr,R.sub.22 is an optional moiety which when present is selected from the group consisting of Leu and Tyr;R.sub.24 -R.sub.

Abstract: A plasma gun is described which is capable of creating and directing a plasma towards a neutralizing plate. The plate is comprised of a material which is chemically inert, metallic, and whose atoms are substantially heavier than the atoms of the plasma gas. The plasma, upon impacting the neutralizing plate, picks up sufficient electrons to cause the ions to revert to their neutral state. The particles, upon hitting the neutralizing plate, are redirected towards a substrate whose surface is to be altered or eroded. A potential may be applied to the neutralizing plate to enable the energy of the reflected particles to be controlled. The neutral atoms, so redirected, provide a desired anisotropic erosion capability.

Abstract: An improvement in immunological methods for quantitative detection of Dirofilaria immitis antibodies in a fluid sample comprising a treatment of the sample with Toxocara canis-derived antigens.

Abstract: A process for detecting the presence of trace amounts of non-fluorescent soluble compounds each having at least one labile hydrogen atom in a carrier solution by adding a non-fluorescent quinone which is reducible to a fluorescent hydroquinone, and irradiating the resulting solution in the absence of oxygen with light of sufficient energy to cause the quinone to be reduced to a hydroquinone. The invention further provides a novel photochemical reactor--recording fluorometer combination and carrier liquid--quinone solution for performing the analysis.

Abstract: The present invention discloses a novel and unique family of agents which reversibly binds molecular oxygen at room temperature.

Abstract: A pile driver is described wherein a piston within an internal combustion engine is rigidly coupled to the pile to be driven. The engine is resiliently coupled to the pile so as to move with the pile. Control circuitry modifies the frequency of operation of the piston so as to make the impulses created thereby synchronous with reflected impulses within the pile.

Abstract: A probe for mounting a transducer, and having a hole extending longitudinal therethrough for a lead, is formed of two end portions having facing intermeshing bevel gears disposed with axes that are at an angle to the axis of the respective end portions. A central portion is mounted to the two end portions for rotation with respect thereto for holding the bevel gears in contact with one another.

Abstract: Improved electrochemical sensors are provided through isostatic processing techniques. Improved electrochemical sensors, especially those suitable for use in metallurgical melts, having, at once, long-term stability, improved sensitivity, and improved physical properties including thermal shock resistance are provided. In accordance with a preferred embodiment, unitary bodies comprising the sensing electrolyte and a source of reference potential are fabricated through isostatic processing techniques. Methods for the preparation of these improved sensors together with methods for the improvement of sensing, especially of oxygen in metallurgical melts are also disclosed.

Abstract: An improved gaseous sulfur dioxide galvanic cell is formed by utilizing a solid electrolyte composed of a mixture of lithium sulfate and silver sulfate. A reference electrode is formed by placing a solid mixture of the electrolyte mixture and metallic silver in contact with a portion of the surface of the solid electrolyte. A gas-type detector electrode is provided by contacting the solid electrolyte with a gold lead at a point spatially separated from the contact point between the reference electrode and electrolyte. Catalyst means are preferably provided to convert the sulfur dioxide to an equilibrium mixture of sulfur dioxide and sulfur trioxide near the electrolyte detector electrode surface. The electrolyte is preferably heated to a temperature at which it is a two-phased mixture of solid solutions for increased long term stability.

Abstract: Antineoplastic compounds of the formula, IIa, ##STR1## wherein: Y is hydrogen or lower alkyl; and Z is a lower alkoxy substituted quinolinylamino radical, a cyano substituted pyrazolylamino radical or a mono- or di-lower alkyl substituted thiazolamino radical, ora nitrogen-containing heterocyclic radical, ora cyano, phenyl, carboxamido or lower alkoxycarbonyl substituted 1-aziridinyl radical ora lower alkyl, formyl or acetylphenyl substituted 1-piperazinyl radical, oran hydroxy or piperidyl substituted 1-piperidyl radical, ora lower alkoxy, amino or halo substituted pyridylamino radical, ora carboxamido, mercapto or methylenedioxy substituted anilino radical, ora radical of the formula, ##STR2## wherein R is hydrogen or lower alkyl and R" is a nitrogen-containing heterocyclic radical, ora butyrolactonyl radical, oran adamantyl radical, ora mono- lower alkoxy substituted phenyl radical, ora substituted lower alkyl radical selected from the group consisting of mercapto lower alkyl, carboxy lower alkyl, mono-, d

Abstract: Dialkenyl diacetylenes, especially divinyl diacetylenes having liquid crystalline phases, are provided. In accordance with certain preferred embodiments, diacetylenes having liquid crystalline phases are provided which may be polymerized while in the liquid crystalline state to yield conjugated polymers. The processes for the polymerization of such liquid crystalline diacetylenes and for the elaboratiPortions of this work have been supported by the Defense Advanced Research Projects Agency, Grant No. DAAK-70-77-C-0045 (5-26502). The United States Government has certain rights in this invention.

Abstract: A biogenic ice nucleation inhibitor, derivable from a source plant which is normally subjected to freezing stress in its natural habitat, is employed for protecting light frost-sensitive plants against frost injury by inhibiting the ice-nucleating activity of the ice-nucleating bacteria normally present on the plants, and thereby reducing the temperature at which frost injury occurs. The inhibitor is applied to the plants in the form of a solution of a water-soluble denaturable proteinaceous material derivable as a water extract of a source plant component which survives the freezing stress to which the source plant is normally subjected in its natural habitat, such as the seed. The inhibitor is also applicable for reducing the temperature at which ice formation occurs in any other medium containing active ice nucleation initiators, such as, for example, the atmosphere and concrete.

Abstract: The disclosure is directed to an apparatus and method for imaging radiation pattern from within a body. In accordance with the preferred method of the invention, there is provided a technique for imaging internal structure of a body which includes the following steps: a radiation-emitting substance is introduced into the body. A miniaturized probe is inserted into the body, the probe being coupled to a cable and including at least one radiation detector surrounded by a coded aperture. Signals are received from the detector via the cable for a series of positions of the probe and for different orientations of the coded aperture with respect to the body. The signals from the detector are processed to obtain an image of the radiation pattern within the body. The imaging hereof allows both the position and the strength of a source (e.g. a tumor) to be determined in the presence of background radiation.

Abstract: Antibodies to human carcinoembryonic antigen (CEA), human alphafetoprotein (AFP) and/or to other anti-human tumor associated antigens (TAA) labeled with technetium-99m (Tc-99m) are administered to a human after the human has been administered anti-CEA, anti-AFP and/or other anti-TAAs, such as human melanoma-associated antigen, human neuroblastoma-associated antigen, human breast cancer-associated antigen, human ovary-associated antigen, human sarcoma-associated antigen, etc. The biodistribution of the labeled product composition accumulates at cancer sites, e.g., tumors that produce or express TAA, due to the affinity that the antibody has for the given tumor antigen. The accumulation at the tumor site(s) of a suitable amount of Tc-99m associated with the antibody allows detection via external scintigraphy and other means. Detection of the Tc-99m antibody composition by external scintigraphy permits localization and detection of tumors in vivo via a semi-noninvasive technique.