Patents Assigned to University
  • Patent number: 12217384
    Abstract: A method for spatial resolution enhanced imaging is provided. The method includes determining a target region of a subject being imaged; estimating an achievable spatial resolution; selecting an increased spatial resolution that is greater than a predetermined spatial resolution and equal to or less than the achievable spatial resolution; and acquiring image data of the target region with the increased spatial resolution. A method for enhancing the contrast between the region of interest and other tissue region in the image data acquired with the increased spatial resolution and other tissue region in image data acquired with the predetermined spatial resolution due to the intrinsic partial volume effect is also provided.
    Type: Grant
    Filed: January 26, 2021
    Date of Patent: February 4, 2025
    Assignees: University of Cincinnati, Children's Hospital Medical Center
    Inventors: Jinghua Wang, Lili He
  • Patent number: 12213768
    Abstract: The biological information measurement device (100) includes: a clip (110) that is attached on the scapha of an auricle in such a way as to clamp the scapha from both sides; and a pulse wave sensor (120) that is disposed on a portion of the clip (110), is arranged in such a way as not to compress the helix when the clip (110) is attached on the scapha of the auricle, and measures biological information of an artery running in the helix. The pulse wave sensor (120) may be a non-contact type sensor that measures the biological information, using transmitted light, and the clip (110) may be configured in such a way that the pulse wave sensor (120) does not come into contact with the helix when the clip (110) is attached in such a way as to clamp the scapha of the auricle from both sides.
    Type: Grant
    Filed: March 28, 2019
    Date of Patent: February 4, 2025
    Assignee: Sapporo Medical University
    Inventor: Yuichi Kato
  • Patent number: 12215017
    Abstract: A sensor, such as a piezoelectric MEMS vibration sensor, includes a frame, a beam array comprising a plurality of beams, and a plurality of masses. Each beam of the plurality of beams has an anchored end and an unanchored end, with each beam being coupled to the frame at the anchored end. The unanchored end of each beam is coupled to a respective mass of the plurality of masses. Each beam of the plurality of beams can be configured to minimize a variation in a voltage output for a limited frequency range. In some implementations, the resonant frequency of each beam corresponds to a sensitivity peak in a limited frequency range.
    Type: Grant
    Filed: May 14, 2020
    Date of Patent: February 4, 2025
    Assignee: The Regents of the University of Michigan
    Inventors: Alison Hake, Karl Grosh
  • Patent number: 12214098
    Abstract: A catalyst adapted for generating hydrogen peroxide induced by a temperature difference and a method for environmental disinfection using the same are provided. The catalyst includes a thermoelectric material distributed on a substrate. The thermoelectric material induces a reaction between water vapor and oxygen contained in the air through a temperature difference to generate hydrogen peroxide, to serve a sterilization function through the hydrogen peroxide generated. The method for environmental disinfection using the catalyst includes the following. The catalyst is placed in an environment with a temperature difference. The catalyst is caused to induce a reaction between water vapor and oxygen contained in air through the temperature difference to generate hydrogen peroxide without applying power, and serve a sterilization function through the hydrogen peroxide generated.
    Type: Grant
    Filed: November 9, 2021
    Date of Patent: February 4, 2025
    Assignee: National Tsing Hua University
    Inventors: Zong-Hong Lin, Yu-Jiung Lin, Imran Khan
  • Patent number: 12217085
    Abstract: An electronic device includes: a host processor configured to control an operation of the electronic device; accelerators of heterogeneous hardware types configured to exchange data with each other through direct communication; and a control unit configured to convert a command received from the host processor, based on a type of each of the accelerators and transfer a result of the converting to a corresponding accelerator among the accelerators.
    Type: Grant
    Filed: August 16, 2021
    Date of Patent: February 4, 2025
    Assignees: Samsung Electronics Co., Ltd., Seoul National University R & DB Foundation
    Inventors: Seung Wook Lee, Jangwoo Kim, Pyeongsu Park
  • Patent number: 12218295
    Abstract: Various embodiments of the disclosure disclose a method for manufacturing a micro Light Emitting Diode (LED) display. The disclosed manufacturing method may include coating a face of a substrate including a circuit portion with a first thickness of a polymer adhesive solution containing a plurality of metal particles, attaching an array of micro LED chips on the polymer adhesive solution, physically connecting a connection pad for each of the array of micro LED chips to the metal particles through heating and pressing the attached plurality of micro LED chips to descend through the polymer adhesive solution, and chemically bonding the metal particles to the connection pad and the circuit portion through heating and pressing so that the micro LED chips are electrically connected to the circuit portion. Various other embodiments are also possible.
    Type: Grant
    Filed: November 29, 2021
    Date of Patent: February 4, 2025
    Assignees: Samsung Electronics Co., Ltd., Research & Business Foundation Sungkyunkwan University
    Inventors: Byunghoon Lee, Taeil Kim, Jamyeong Koo, Juseung Lee
  • Patent number: 12215419
    Abstract: Methods of producing an optical surface atop an exterior of a substrate that includes smoothing the exterior using an ALD process to sequentially deposit ALD layers to produce one or more ALD films that fill spaces between spaced-apart asperities existing on the exterior, and thereafter depositing a reflective material on the smoothed exterior of the substrate to produce the optical surface. The smoothing resulting from depositing the ALD film on the exterior of the substrate causes the grain size of the reflective material to be reduced in comparison to the grain size that would exists without having deposited the ALD film on the exterior of the substrate. The smoothing is sufficient to cause a reduction in grain size that results in a reduction in plasmon absorption in the optical surface in comparison to the plasmon absorption that would otherwise exist without having reduced the grain size of the reflective material.
    Type: Grant
    Filed: April 29, 2022
    Date of Patent: February 4, 2025
    Assignees: Eagle Technology, LLC, University of Colorado Boulder
    Inventors: James Throckmorton, Tyler Myers, Rebecca Borrelli, Malcolm O'Sullivan, Tukaram Hatwar, Steven M. George
  • Patent number: 12214086
    Abstract: The invention generally relates to polymer-based nano-structures. More particularly, the invention relates to novel, surface-functionalized, guest-host polymer nano-assemblies and nano-delivery vehicles useful in diverse fields including drug delivery, diagnostics and specialty materials. The nano-assemblies and nano-delivery vehicles of the invention are afforded via simplify and reliable approaches.
    Type: Grant
    Filed: July 31, 2021
    Date of Patent: February 4, 2025
    Assignee: University of Massachusetts
    Inventors: Sankaran Thayumanavan, Jiaming Zhuang, Hui Wang
  • Patent number: 12213825
    Abstract: A method of x-ray fluoroscopy images a region of interest at distinct first and second imaging projection angles using digital subtraction x-ray fluoroscopic imaging with a fiducial marker board positioned in a field of view containing the region of interest to produce first and second sets of images. Image segmentation information is determined to identify an anatomical feature in the region of interest imaged in the first set of images and the second set of images. The region of interest is then imaged using x-ray fluoroscopic imaging, again with the fiducial marker board positioned in a third field of view containing the region of interest, but without digital subtraction, to produce a third set of images. A virtual image of the anatomical feature is projected onto the third set of images, computed from the image segmentation information and from a predetermined geometric relationship of markers within the fiducial marker board.
    Type: Grant
    Filed: April 29, 2022
    Date of Patent: February 4, 2025
    Assignees: The Board of Trustees of the Leland Stanford Junior University, Pulmera, Inc.
    Inventors: Bryan I. Hartley, Harmeet Bedi, Rene Vargas-Voracek, Norbert J. Pelc
  • Patent number: 12215343
    Abstract: The present disclosure provides a DNA-targeting RNA that comprises a targeting sequence and, together with a modifying polypeptide, provides for site-specific modification of a target DNA and/or a polypeptide associated with the target DNA. The present disclosure further provides site-specific modifying polypeptides. The present disclosure further provides methods of site-specific modification of a target DNA and/or a polypeptide associated with the target DNA The present disclosure provides methods of modulating transcription of a target nucleic acid in a target cell, generally involving contacting the target nucleic acid with an enzymatically inactive Cas9 polypeptide and a DNA-targeting RNA. Kits and compositions for carrying out the methods are also provided. The present disclosure provides genetically modified cells that produce Cas9; and Cas9 transgenic non-human multicellular organisms.
    Type: Grant
    Filed: December 22, 2021
    Date of Patent: February 4, 2025
    Assignees: The Regents of the University of California, University of Vienna
    Inventors: Jennifer A. Doudna, Martin Jinek, Krzysztof Chylinski, Emmanuelle Charpentier
  • Patent number: 12215409
    Abstract: The present invention relates to a high-strength, high-corrosion resistance ternary magnesium alloy and a preparation method therefor, the magnesium alloy comprising the following element components by mass percentage: 8-12 wt % of Y, 0.6-3 wt % of Al and the remainder being Mg. The method comprises: (1) under a protective atmosphere, preparing a Mg—Y intermediate alloy, an aluminum ingot and a magnesium ingot into a magnesium alloy melt; (2) under a protective atmosphere, allowing the magnesium alloy melt to stand after stirring, then carrying out refining, degassing, and slag removal, allowing the magnesium alloy melt to stand again, then thermally insulating to obtain a magnesium alloy liquid; and (3) casting and molding the magnesium alloy liquid under a protective atmosphere, and forming a cast ingot; the three steps above ultimately obtain a high-strength, high-corrosion resistance ternary magnesium alloy.
    Type: Grant
    Filed: March 15, 2021
    Date of Patent: February 4, 2025
    Assignee: Shanghai Jiao Tong University
    Inventors: Yangxin Li, Xiaoqin Zeng, Qingchun Zhu, Tao Ying
  • Patent number: 12213997
    Abstract: Among the various aspects of the present disclosure is the provision of compositions and methods for the generation of a supporting matrix for cells, such as stem cells and NP cells (and precursors thereof). For example, an NP cell-specific phenotype precursor cell can be an adult NP cell, such as a cell taken from the adult and degenerated intervertebral disc and/or a progenitor cell, such as stem cells, induced pluripotent cells, pluripotent cells, precursor cells, or stromal cells.
    Type: Grant
    Filed: February 2, 2021
    Date of Patent: February 4, 2025
    Assignee: Washington University
    Inventors: Lori Setton, Marcos Barcellona, Julie Speer
  • Patent number: 12215386
    Abstract: The invention relates to methods and kits for diagnosing and/or treating appendicitis in a subject, comprising obtaining a biological sample rom said subject; detecting RNA expression levels of at least three or more biomarkers in the biological sample and comparing the expression levels of said at least three or more biomarkers to a control sample wherein an increase or decrease in the level of expression of said at least three or more biomarkers as compared to the control sample is indicative of appendicitis.
    Type: Grant
    Filed: June 9, 2021
    Date of Patent: February 4, 2025
    Assignee: The George Washington University
    Inventors: Lakhmir S. Chawla, Timothy A. McCaffrey
  • Patent number: 12219667
    Abstract: Processing flows and related systems and methods are disclosed. A computing system includes one or more data interfaces, one or more other components, and a controller. The one or more data interfaces are configured to provide an interface to a data source. The one or more other components include one or more controller plugins, one or more processing nodes, or both the one or more controller plugins and the one or more processing nodes. The controller is configured to manage interactions between the one or more data interfaces and the one or more other components and enable a user to chain together the one or more data interfaces and the one or more other components according to one or more flows. The one or more controller plugins are configured to provide results of the one or more flows to one of a user interface and a system interface.
    Type: Grant
    Filed: October 30, 2020
    Date of Patent: February 4, 2025
    Assignees: Battelle Energy Alliance, LLC, University of Utah Research Foundation
    Inventors: Aniqua Z. Baset, Christopher D. Becker, Samuel Ramirez, Sneha K. Kasera, Kurt W. Derr
  • Patent number: 12216776
    Abstract: A system for noise-resistant quantum communication using hyperentanglement includes a quantum system that includes a plurality of qubits, a processor, and a memory. The memory includes instructions stored thereon, which, when executed by the processor, cause the quantum system to access a signal of a quantum system that includes a plurality of qubits and obtain hyperentanglement of the plurality of qubits via an entanglement source. The hyperentanglement of the plurality of qubits is in at least two dimensions, including a first dimension and a second dimension. The instructions, when executed, further cause the quantum system to transmit the hyperentangled plurality of qubits via a communication channel; perform a communication of the signal with the first dimension of the at least two dimensions; and filter results of the communicated signal based on the second dimension of the at least two dimensions.
    Type: Grant
    Filed: November 10, 2022
    Date of Patent: February 4, 2025
    Assignees: University of Maryland, College Park, POSTECH RESEARCH AND BUSINESS DEVELOPMENT FOUNDATION
    Inventors: Giuliano Scarcelli, Yoon-Ho Kim, Jin-Hun Kim
  • Patent number: 12218506
    Abstract: Disclosed herein are systems and methods for sliding mode control enabled hybrid energy storage. In a specific embodiment, the system can include: a photovoltaic power generation unit; a hybrid energy storage system, where the hybrid storage system can include a battery, a supercapacitor, where the supercapacitor provides excess power demand based on different loading conditions, and a rate limiter; a sliding mode controller, where the slide mode controller controls a current in a hybrid energy storage system; a supercapacitor charging control; and a proportional integral controller. In a specific embodiment, the method can include: decoupling an average and transient hybrid energy storage system current with a single rate limiter, where the decoupling includes a battery discharge rate; regulating a battery current with a first sliding mode controller; and regulating a supercapacitor current with a second sliding mode controller, where a supercapacitor provides excess power demand.
    Type: Grant
    Filed: August 5, 2022
    Date of Patent: February 4, 2025
    Assignee: University of Louisiana at Lafayette
    Inventors: Ali Jafarian Abianeh, Farzad Ferdowsi
  • Patent number: 12216045
    Abstract: A gas measurement apparatus includes an optical resonator that resonates light, a light source that generates light for irradiation of the optical resonator, and a photodetector that detects light taken out of the optical resonator. The optical resonator includes a plurality of mirrors, a holding member, a hollow tubular member, a hollow tubular member, and a temperature adjustment instrument. The holding member is lower in thermal expansion coefficient than the hollow tubular member. The hollow tubular member includes a portion higher in thermal conductivity than the holding member and a bellows higher in elasticity than a first portion. The hollow tubular member is equal to or higher than the hollow tubular member in thermal conductivity, and is provided as far as positions of the plurality of mirrors on an inner side of the bellows.
    Type: Grant
    Filed: January 26, 2023
    Date of Patent: February 4, 2025
    Assignees: SHIMADZU CORPORATION, National University Corporation Tokai National Higher Education and Research System
    Inventors: Tatsuya Ikehara, Tetsuo Furumiya, Koji Tojo, Hideki Tomita
  • Patent number: 12213973
    Abstract: Disclosed are substituted aminoquinoline and aminopyridine compounds and their use as bacterial nitric oxide synthase (bNOS) inhibitors. Also disclosed are pharmaceutical compositions comprising the compounds, and methods of using the compounds and pharmaceutical compositions for treating a subject having or at risk for developing a disease or disorder that is associated with bNOS activity.
    Type: Grant
    Filed: October 18, 2022
    Date of Patent: February 4, 2025
    Assignee: Northwestern University
    Inventors: Richard Bruce Silverman, Pathum Manjula Weerawarna
  • Patent number: 12214150
    Abstract: The disclosed methods relate to forming microneedle arrays from a production mold that comprises a flexible mold material. The disclosed methods can be used to reproducibly manufacture undercut dissolvable and coated microneedle arrays with various shapes and structures.
    Type: Grant
    Filed: May 15, 2020
    Date of Patent: February 4, 2025
    Assignee: University of Pittsburgh—Of the Commonwealth System of Higher Education
    Inventors: Louis D. Falo, Jr., Emrullah Korkmaz
  • Patent number: 12214329
    Abstract: The disclosure discloses a nicotinamide dummy template surface molecularly imprinted polymer, a preparation method and application thereof, and belongs to the technical field of chemical materials. The preparation method of the disclosure includes the steps of preparing a modified silica gel carrier, preparing a dummy template surface molecularly imprinted polymer and the like. The disclosure uses nicotinamide, a structural analogue of imidacloprid and acetamiprid, as a dummy template to prepare a silica gel surface molecularly imprinted polymer. The polymer not only can effectively avoid pollution caused by the leakage of template molecules, but also can specifically remove imidacloprid and acetamiprid from water-soluble tea extracts. The removal rate of imidacloprid and acetamiprid is greater than 96% and 93%, respectively, and the loss of tea polyphenols in the extracts is less than 10%.
    Type: Grant
    Filed: December 15, 2021
    Date of Patent: February 4, 2025
    Assignee: Jiangnan University
    Inventors: Hongxin Wang, Jingyu Chen, Shijia Wu, Xinlin Wei, Xin Huang, Li Wang