Abstract: This invention provides an X-ray CT image processing method that allows more flexible expression by expressing X-ray absorption coefficients probabilistically, makes it possible to acquire reconstructed images that are comparable to those obtained by conventional methods but involve lower X-ray doses, and can reduce beam-hardening artifacts. A probability distribution for the observation of projected X-rays is set and statistical inference is performed. Said probability distribution is expressed in terms of the process of observing a multiple-X-ray sum resulting from multiple projected X-rays being incident upon a detector. Bayesian inference in which the expected value of the posterior distribution is used for statistical inference is performed on the basis of a prior distribution for X-ray absorption coefficients, said prior distribution having parameters for the material and the observation process in terms of which the multiple-X-ray sum is expressed.

Abstract: Raman scattering, while a powerful and versatile technique, relies of the detection of weak signals. Detecting the signal can be difficult if there is interference, especially if the interference comes from scattered stray light of the laser used to generate the Raman signal. Described here is a frequency modulation technique in combination with heterodyne detection that simultaneously rejects interference from ambient light as well as from scattered stray laser light. This provides a means to detect Raman signal and discriminate against scattered light without using an expensive and bulky spectrometer.

Abstract: A method for regulating Src and its downstream signaling pathway which includes binding between Src and Na+/K+-ATPase is disclosed. The Na+/K+-ATPase/Src complex is a functional receptor for cardiotonic steroids such as ouabain. Also disclosed are Src inhibitors or activators which include either Na+/K+-ATPase or Src that interfere with the interaction between the Na/K-ATPase and Src, act via a different mechanism from ATP analogues, and is pathway (Na+/K+-ATPase) specific. Also disclosed is use of said Src-modulating peptides for treatment of cancer.

Abstract: Circuits and circuit systems to record activity (e.g., peripheral nerve activity) are provided. The circuits advantageously have good noise characteristics (e.g., low noise), as well as low power consumption and low area. A circuit can be implantable (e.g., in a human subject). Methods of designing, manufacturing, and using such circuits and circuit systems are also provided.

Abstract: The present invention relates to a stabilized monomer dispersion containing inorganic oxide nanoparticles with high refractive index in which the refractive index of the inorganic oxide nanoparticles is greater than 1.65 and the average particle size of the high refractive inorganic oxide nanoparticles ranges from 1 to 100 nm and its content is in a range of from 1.0% by weight to 10.0% by weight based on the total weight of the monomer dispersion. The present invention also relates to a process for preparing the stabilized monomer dispersion containing high refractive inorganic oxide nanoparticles.

Abstract: The present disclosure provides methods and compositions related to the cytosolic delivery of proteins and cell-impermeable small molecules into live cells using an endosomolytic dimer of cell-penetrating peptide TAT.

Abstract: The present invention is related generally to a method for screening subjects to determine those subjects more likely to develop diabetes by quantization of insulin producing cells. The present invention is also related to the diagnosis of diabetes and related to monitor disease progression or treatment efficacy of candidate drugs.

Abstract: A functionalized nanomaterial having an average particles size of less than 10 nm comprising an iron oxide nanoparticle core and a bis(diarylphosphinomethyl) dopamine based ligand layer anchored to the iron oxide nanoparticle core is disclosed. In addition, a catalyst composition for use in a variety of chemical transformations wherein the bisphosphine groups of the functionalized nanomaterial chelate a catalytic metal is disclosed. In addition, a method for producing the functionalized nanomaterial and a method for the hydroformylation of olefins to aldehydes employing the functionalized nanomaterial with high conversion percentage and high selectivity are disclosed.

Abstract: An LED driver provides constant output power with wide range output current and voltage. A parallel resonant tank configuration is supplemented by resonant gain clamping circuit configured to partially cancel voltage across the resonant capacitor during half-bridge switching operation. Voltage between the resonant components is clamped to one-half a driver input voltage, ensuring inductive switching of the half-bridge. An output transformer has a primary winding coupled across the resonant capacitor, with a center tap defining first and second portions. An output voltage clamping circuit is coupled across the DC input power source and to the center tap, wherein maximum voltage across the primary is clamped based on a relationship between respective numbers of turns in the first and second portions, and maximum voltage across a secondary winding is clamped based on a relationship between the respective numbers of turns in the secondary winding and the first and second portions.

Abstract: A biomass pyrolysis process is provided in which biomass feedstock is mixed with a heat carrier. The heat carrier at least partly comprises char. The ratio by weight of biomass to char is in the range 1:1 to 1:20. The process may be carried out by in a screw/auger pyrolysis reactor in which the solid feedstock components are conveyed along the reactor by a first screw. A second screw conveys at least a portion of the solid products of the biomass pyrolysis back to a heat transfer medium input port. Thus, the heat transfer medium includes char from the biomass pyrolysis.

Abstract: Despite its narrow therapeutic window, lithium is regarded as the gold standard comparator and benchmark treatment for mania. Attempts to find new drugs with similar therapeutic activities have yielded new chemical entities. However, these new drugs have yet to match the many bioactivities attributable to lithium's efficacy for the treatment of neuropsychiatric diseases. Consequently, an intense effort for re-engineering lithium therapeutics using crystal engineering is underway. The evaluation of pharmacokinetics of previously unexplored lithium salts with organic anions (i.e. lithium salicylate) has found that these lithium salts exhibit profoundly different pharmacokinetics compared to the more common FDA approved salt, lithium carbonate, in rats. Remarkably, lithium salicylate produced elevated blood and brain levels of lithium beyond 48 hours post-dose without the sharp peak that contributes to the toxicity problems of current lithium therapeutics.

Abstract: A field emission electron source includes a linear carbon nanotube structure, an insulating layer and at least one conductive ring. The linear carbon nanotube structure has a first end and a second end. The insulating layer is located on outer surface of the linear carbon nanotube structure. The first conductive ring includes a first ring face 1301 and a second ring face, an end surface of the linear carbon nanotube structure, and the first ring face are coplanar.

Abstract: An organic photodetector includes an anode and a cathode facing each other and an active layer between the anode and the cathode and including a p-type semiconductor and an n-type semiconductor, wherein an energy barrier between the anode or the cathode and the active layer is greater than or equal to about 1.3 eV, a difference between a HOMO energy level of the p-type semiconductor and a LUMO energy level of the n-type semiconductor is greater than or equal to about 0.8 eV.

Abstract: A biocompatible membrane comprised of alginate and hyaluronate. The membrane may be used to prevent unwanted scarring after surgery. The tissue adherence and the rate of bioresorption of the membrane may be modified through an external stimulus comprising a sequestering agent and a viscosity modifier.

Abstract: An isolated nucleic acid agent is disclosed comprising a nucleic acid sequence which downregulates expression of a gene product of a Varroa destructor mite. Compositions comprising same and uses thereof are also disclosed.

Abstract: The present invention provides a culture method of cells and/or tissues including culturing cells and/or tissues in a suspended state by using a medium composition wherein indeterminate structures are formed in a liquid medium, the structures are uniformly dispersed in the solution and substantially retain the cells and/or tissues without substantially increasing the viscosity of the solution, thus affording an effect of preventing sedimentation thereof, and the like.

Abstract: The use of plasmonics enhanced photospectral therapy (PEPST) and exiton-plasmon enhanced phototherapy (EPEP) in the treatment of various cell proliferation disorders, and the PEPST and EPEP agents and probes used therein.

Abstract: The present invention provides a unit dosage of Apadenoson, a pharmacological stress agent, and use of the same as a pharmacologic agent for myocardial perfusion imaging.

Abstract: An illumination system defined a primary optical axis is provided. The illumination system comprises a light source, a first lens group, an integrator rod, and a second lens group successively located on the primary optical axis. The light source is configured to output a light. The first lens group is configured to reduce an aperture angle of the light to about 27 degrees. The integrator rod is configured to make the light uniformly. The second lens group is configured to amplify an illumination field of the light and reduce the aperture angle of the light to about 3 degrees.

Abstract: Citral, cinnamaldehyde, carvacrol, and allspice oil were found to be highly effective antimicrobials, producing statistically significant reductions in Escherichia coli populations within minutes. In addition, synergy was observed between silver ions and these essential oils, thereby lessening the amount of the plant antimicrobial required to produce the same effect. Based on these observations, compositions including these agents and there use as an antimicrobial treatment that is safe for human consumption, are active in the presence of organic matter, are provided.