Abstract: A method for dental implant path planning is applied to a computer displaying a planning interface having a jaw image zone, a cross-section image zone and a reference zone, and comprises steps of: displaying a jaw image in the jaw image zone; generating a dental arch according to the jaw image; labeling an implant position in the jaw image; lapping an implant image over the jaw image according to the implant position; displaying at least two cross-section images in the cross-section image zone according to the implant image and the jaw image; displaying a plurality of characteristic values in the reference zone according to a plurality of characteristic distances in the cross-section images; and adjusting the position of the implant image relative to the jaw image by referring to the cross-section images or the characteristic values.

Abstract: Systems and methods for predicting protein-ligand interactions are disclosed. An exemplary method can include identifying a set of structural neighbours of the query proteins, where each of contains ligands. The method can also determine a similarity score for each of the structural neighbours representing configuration similarity and interaction tendency between the structural neighbours and predict protein-ligand interactions of the one or more query proteins using the similarity scores.

Abstract: The compositions and methods relate to an organic polymer-inorganic particle sensor material for detecting analytes. Interactions between the polymer and the particles are affected by the presence of analyte, which displaces the polymer and increases its free volume. This change in free volume can be detected, e.g., using an embedded piezoresistive microcantilever (EPM) sensor. Analytes that can be detected include noxious substances, such as hydrogen cyanide gas and carbon monoxide.

Abstract: A first aspect of the invention is a compound (sometimes also referred to herein as an “active agent” or “active compound”) of Formula Ia, or more particularly Formula Ib, or a pharmaceutically acceptable salt or prodrug thereof. Compositions thereof and methods of using the same (e.g. for the treatment of a neurological disease) are also described.

Abstract: Photovoltaic devices are produced using a minimally modified standard process flow by forming lateral P-I-N light-sensitive diodes on silicon islands that are isolated laterally by trenches performed by RIE, and from an underlying support substrate by porous silicon regions. P+ and N+ doped regions are formed in a P? epitaxial layer, trenches are etched through the epitaxial layer into a P+ substrate, a protective layer (e.g., SiN) is formed on the trench walls, and then porous silicon is formed (e.g., using HF solution) in the trenches that grows laterally through the P+ substrate and merges under the island. The method is either utilized to form low-cost embedded photovoltaic arrays on CMOS IC devices, or the devices are separated from the P+ substrate by etching through the porous silicon to produce low-cost, high voltage solar arrays for solar energy sources, e.g., solar concentrators.

Abstract: A PEFS (Piezoelectric Finger Sensor) acts as an “electronic finger” capable of accurately and non-destructively measuring both the Young's compression modulus and shear modulus of tissues with gentle touches to the surface. The PEFS measures both the Young's compression modulus and shear modulus variations in tissue generating a less than one-millimeter spatial resolution up to a depth of several centimeters. This offers great potential for in-vivo early detection of diseases. A portable hand-held device is also disclosed. The PEF offers superior sensitivity.

Abstract: The embodiments disclosed herein relate to various medical device components, including components that can be incorporated into robotic and/or in vivo medical devices. Certain embodiments include various actuation system embodiments, including fluid actuation systems, drive train actuation systems, and motorless actuation systems. Additional embodiments include a reversibly lockable tube that can provide access for a medical device to a patient's cavity and further provides a reversible rigidity or stability during operation of the device. Further embodiments include various operational components for medical devices, including medical device arm mechanisms that have both axial and rotational movement while maintaining a relatively compact structure. medical device winch components, medical device biopsy/stapler/clamp mechanisms, and medical device adjustable focus mechanisms.

Abstract: Cardiopulmonary resuscitation (CPR) training manikins and methods of using CPR training manikins are described.

Abstract: A composite permanent magnet synchronous machine includes a permanent magnet synchronous machine module having a rotor unit and a stator unit; a bottom base having an accommodation space; a top cover having a front surface; and a shaft penetrating through the front surface. The rotor unit has P rotor magnets and the stator unit has S slots, wherein a tooth part is defined between every two adjacent slots, and a coil is wound on the tooth part, where P is 38N, S is 36N, and N is a positive integer; or P is 34M, S is 36M, and M is a positive integer. The machine is suitable for wind power generators or any other machine structure.

Abstract: An intra-cavity optical parametric oscillator. The oscillator includes means for providing a non-linear loss for suppressing relaxation oscillations.

Abstract: A method for achieving atomicity while inspecting a running computer process using a copy-on-write process in a supervisor to generate a copy of a target's memory page being written to, prior to executing the write, the copy along with any unwritten to memory pages in the target being mapped to a measurement agent (MA) and used to reflect the state of the target at a particular moment in time which state when observed by the MA provides an atomic runtime inspection.

Abstract: Compositions and methods for making a three dimensional structure comprising: designing a three-dimensional structure; melting the three-dimensional structure from two or more layers of a metal powder with a high energy electron or laser beam is described herein. The position where the metal is melted into the structure is formed along a layer of metal powder, wherein the location and intensity of the beam that strikes the metal layer is based on the three-dimensional structure and is controlled and directed by a processor. The instant invention comprises a novel dry state sonication step for removing metal powder that is not melted from the three dimensional structure.

Abstract: A phosphate-containing nanoparticle delivery vehicle includes a nanoparticle, an active ingredient, and a phosphodiester moiety connecting the nanoparticle and the active ingredient and forms a prodrug. The nanoparticle delivery vehicle achieves the function of increasing hydrophilicity of the active ingredient and specificity against tumor cells. Advantages of the nanoparticle material include biocompatibility, magnetism and/or controllable drug release.

Abstract: Foliamngiferosides having the general formula (I) are disclosed, wherein R is H or —OCH. The preparation method of the compounds, pharmaceutical compositions comprising the compounds as the active ingredients, the use of the compounds and the pharmaceutical compositions for inhibiting the activity of ?-glucosidase are also disclosed. The foliamangiferosides can be used in preparing drugs for treating diabetes.

Abstract: A technique for reducing an electromagnetic noise entering an electrode or a drift of a signal due to a fluctuation in the ambient temperature is provided to improve the S/N ratio of a signal originating from a component of interest. A dummy electrode having the same structure as an ion-collecting electrode is provided within a lower gas passage at a position where dilution gas with no sample gas mixed therein flows. A differential amplifier is provided to perform differential detection between output A of a current amplifier connected to the ion-collecting electrode and output B of a current amplifier connected to the dummy electrode. The differential signal is free from a common mode noise or drift and hence accurately reflects the amount of the component of interest.

Abstract: A comparator is provided and the comparator includes a comparing input unit and a latching unit. Wherein, the comparing input unit has a first input receiving a first comparing signal and has a second input receiving a second comparing signal. The comparing input unit drives a first intermediate node signal at a first intermediate node depending on the first comparing signal according to a first strobe signal, and the comparing input unit drives a second intermediate node signal at a second intermediate node depending on the second comparing signal according to the first strobe signal. The latching unit determines a comparing result according to at least one of the first intermediate node signal and the second intermediate node signal. In addition, the latching unit latches the comparing result according to a second strobe signal.

Abstract: A system for timbral change, capable of changing timbres included in an existing music audio signal to arbitrary timbres. Replaced harmonic peak parameters are created by replacing a plurality of harmonic peaks included in harmonic peak parameters, which are stored in a separated audio signal analyzing and storing section 3 and indicate relative amplitudes of n-th order harmonic components of each tone generated by a musical instrument of a first kind, with harmonic peaks included in harmonic peak parameters, which are stored in a replacement parameter storing section 6 and indicate relative amplitudes of n-th order harmonic components of each tone generated by a musical instrument of a second kind and corresponding to each tone generated by the musical instrument of the first kind. A synthesized separated audio signal generating section 7 generates a synthesized separated audio signal for each tone using parameters other than the harmonic peak parameters and the replaced harmonic peak parameters.

Abstract: A computerized method for optimizing parameters is described. A system can initialize a group of parameters to respective values within a set of allowable models and bound a partition function across a number of variable pairs to generate a plurality of bounds. The system can also determine new values for the group of parameters that minimize a sum of the plurality of bounds. The system can set the group of parameters to the new values and optimize the parameters by iteratively performing the bounding, determining and setting. The system can stop optimizing when a termination condition is reached.

Abstract: The method and system of this invention provides for core muscle strengthening. The method comprises the step of: providing an apparatus (10) that provides resistance and assistance during core muscle training using dynamic therapeutic movement for chest, back, abdominal and leg musculature to strengthen and condition muscles of the axial skeleton and lower extremities of a performing user. In one embodiment, the method also is for non-invasive physical therapy.

Abstract: A flow chamber and method for detecting the presence of one more cell produced analytes under flow conditions. The flow chamber includes two compartments separated by a permeable membrane on which a plurality of cells may be positioned. The permeable membrane shields one or more analyte sensors positioned one compartment from the convective transport forces of a fluid flow within the other compartment to allow reliable and accurate detection of cell-produced analytes and determination of the concentration of cell-produced analytes.