Patents Assigned to University
  • Antimicrobial compositions for treating microbial infections
    Patent number: 8778913
    Abstract: The disclosure provides compounds and methods to treat a microbial or a bacterial pathogenesis, and demonstrates that the S. aureus pigment is a virulence factor and potential novel target for antimicrobial therapy.
    Type: Grant
    Filed: February 1, 2012
    Date of Patent: July 15, 2014
    Assignee: The Regents of the University of California
    Inventors: Victor Nizet, George Y. Liu, Eric Oldfield, Yongcheng Song
  • Endoscopic tube delivery system
    Patent number: 8777840
    Abstract: An apparatus is disclosed. In some embodiments, the apparatus comprises an endoscope comprising a first distal end portion, and a tube comprising a second distal end portion, wherein the endoscope and the tube are in a side-by-side relationship and are coupled at distal end portions of the endoscope and the tube using a single coupling device.
    Type: Grant
    Filed: November 16, 2010
    Date of Patent: July 15, 2014
    Assignee: The Regents of the University of California
    Inventor: Peter C. Belafsky
  • Cystine knot peptides binding to alpha IIb beta 3 integrins and methods of use
    Patent number: 8778888
    Abstract: Disclosed are peptides having a cystine knot structural motif and comprising a sequence engineered for specificity against ?IIb?3 integrin, found on platelets, and a method of using the same in anti-thrombotic therapies. The present peptides utilize a cystine knot scaffold derived from modified agouti-related protein or agatoxin, An alternate library screening strategy was used to isolate variants of peptides that selectively bound to ?IIb?3 integrin or to both ?IIb?3 and ?V?3 integrins. Unique consensus sequences were identified within the identified peptides suggesting alternative molecular recognition events that dictate different integrin binding specificities. In addition, the engineered peptides prevented human platelet aggregation in a plasma-based assay and showed high binding affinity for ?IIb?3 integrin.
    Type: Grant
    Filed: November 2, 2010
    Date of Patent: July 15, 2014
    Assignee: The Board of Trustees of the Leland Stanford Junior University
    Inventors: Jennifer R. Cochran, Adam P. Silverman, Mihalis S. Kariolis
  • Generation and data management of a medical study using instruments in an integrated media and medical system
    Patent number: 8782063
    Abstract: In general, a computer-implemented method is described for receiving one or more requests to generate a medical study, retrieving from one or more data repositories one or more medical study instruments, receiving a selection of a particular medical study instrument to use in the medical study, generating by one or more computers a list of one or more research collaborators invited to review the medical study, and generating by one or more computers a list of one of more participants invited to join the medical study. Additionally, the computer-implemented method generates by one or more computer systems a data filter to format medical data from a first data format to a second data format, wherein the second data format complies with a third data format associated with one or more medical study instruments.
    Type: Grant
    Filed: May 5, 2010
    Date of Patent: July 15, 2014
    Assignee: Universal Research Solutions, LLC
    Inventor: Ali Adel Hussam
  • Periodic signal processing method, periodic signal conversion method, periodic signal processing device, and periodic signal analysis method
    Patent number: 8781819
    Abstract: The invention relates to a periodic signal processing method, a periodic signal conversion method, and a periodic signal processing device capable of reducing the influence of periodicity without using a spectral model. Time windows are arranged such that a center of each of the time windows is at a division position which divides a fundamental frequency in a temporal direction into fractions 1/n (where n is an integer equal to or larger than 2) so as to extract a plurality of portions of different ranges from a signal having periodicity. A power spectrum for the plurality of portions extracted by the respective time windows is calculated, and the calculated power spectrum is added with a same ratio.
    Type: Grant
    Filed: July 18, 2008
    Date of Patent: July 15, 2014
    Assignee: Wakayama University
    Inventors: Hideki Kawahara, Masanori Morise, Toru Takahashi, Toshio Irino
  • O-methylated rapamycin derivatives for alleviation and inhibition of lymphoproliferative disorders
    Patent number: 8778961
    Abstract: The present invention relates to methods of alleviating and inhibiting a lymphoproliferative disorder in a mammal, the method comprising administering one or more rapamycin derivatives (including rapamycin) to the mammal. Further, the invention provides a method for identifying agents which are useful for alleviating and inhibiting a lymphoproliferative disorders, as well as a method for identifying agents which are capable of inhibiting metastasis of lymphatic tumors in a mammal.
    Type: Grant
    Filed: July 6, 2010
    Date of Patent: July 15, 2014
    Assignee: The Trustees of the University of Pennsylvania
    Inventors: Mariusz A. Wasik, Leslie M. Shaw
  • Axially oriented confined crystallization multilayer films
    Patent number: 8778245
    Abstract: A method of forming a confined crystallization multilayer film includes coextruding a plurality of first polymer layers and a plurality of second polymer layer to form a multilayer film wherein each first polymer layer is sandwiched between second polymer layers and axially orienting the multilayer film at a temperature below the melting temperature (Tm) of the second polymer layer and to a thickness such that each first polymer layer forms a high aspect ratio substantially crystalline lamellae.
    Type: Grant
    Filed: April 15, 2011
    Date of Patent: July 15, 2014
    Assignee: Case Western Reserve University
    Inventors: Anne Hiltner, Eric Baer, Yijian Lin, Joel Carr
  • Device and electrode having nanoporous graphite with lithiated sulfur for advanced rechargeable batteries
    Patent number: 8778537
    Abstract: Methods, systems and devices are implemented in connection with rechargeable batteries. One such device includes a cathode that has lithiated sulfur. The device also includes a porous structure having pores containing the lithium-sulfide particles introduced during a manufacturing stage thereof.
    Type: Grant
    Filed: October 28, 2010
    Date of Patent: July 15, 2014
    Assignee: The Board of Trustees of the Leland Stanford Junior University
    Inventors: Yi Cui, Yuan Yang, Matthew McDowell, Ariel Jackson
  • Polyamine derivatives
    Patent number: 8779195
    Abstract: A compound having the general formula (I) or a pharmacologically acceptable salt thereof: X—NH—Y—NH—R1??(I) [wherein X represents R2—SO2— in which R2 represents an optionally substituted lower alkyl group or phenyl group; Y represents a group selected from the group consisting of —R3—NH—R4—, —R5—NH—R6—NH—R7—, —R8—NH—R9—NH—R10—NH—R11—and —R12—NH—R13—NH—R14—NH—R15— in which R3 to R15 each independently represent a C3 to C5 alkylene group; and R1 represents hydrogen or an optionally substituted lower alkyl group, with the proviso that the case where X represents a tosyl group, Y represents —(CH2)3—NH—(CH2)4—NH—(CH2)3—and R1 represents hydrogen is excepted].
    Type: Grant
    Filed: November 12, 2007
    Date of Patent: July 15, 2014
    Assignee: Nihon University
    Inventors: Muneharu Miyake, Tadashi Kusama, Takashi Masuko
  • Scintillators and applications thereof
    Patent number: 8779365
    Abstract: Scintillators of various constructions and methods of making and using the same are provided. In some embodiments, a scintillator comprises at least one radiation absorption region and at least one spatially discrete radiative exciton recombination region.
    Type: Grant
    Filed: April 19, 2011
    Date of Patent: July 15, 2014
    Assignee: Wake Forest University
    Inventor: Richard T Williams
  • Corona-wire unipolar aerosol charger
    Patent number: 8779382
    Abstract: This invention relates to the reduction of charged particle loss by radially introducing sheath air from the porous wall. The corona-wire unipolar aerosol charger of the present invention includes a charging chamber, at least one aerosol inlet channel, a corona wire, an annular sheath air inlet opening, a porous tube defining a charging chamber, an annular sheath air outlet opening, and an aerosol outlet channel. The sheath air inlet opening is for radially introducing a sheath air flow into the charging chamber. The charged particles will not deposit on the wall surface of the charger if the radial velocity of the introduced sheath air at the wall is higher or comparable to the electrostatic velocity of charged particles. The dilution effect of charged particle due to the use of clean air can be further minimized by redirecting the excess clean air to the outside of the charger.
    Type: Grant
    Filed: May 16, 2013
    Date of Patent: July 15, 2014
    Assignee: National Chiao Tung University
    Inventors: Chuen-Jinn Tsai, Chih-Liang Chien, Virat Wattanamekhinkul
  • Apparatus for quantifying unknown stress and residual stress of a material and method thereof
    Patent number: 8780348
    Abstract: An apparatus for quantifying unknown stress and residual stress of a material to be tested, the material being a birefringent or temporary birefringent material, which includes a light source, a polarizer in front of the light source for converting a light beam from the light source into a beam with linear polarization, a first quarter-wave plate in front of the polarizer for generating circular polarization, a standard material, a second quarter-wave plate, an analyzer, a loading unit, a spectrometer for obtaining transmissivity spectrum of the standard material under the wavelength of the light source and a detecting module connected to the spectrometer to have the transmissivity spectrum of the material to be tested and consequently a stress quantifying formula for the standard material.
    Type: Grant
    Filed: September 18, 2012
    Date of Patent: July 15, 2014
    Assignee: National Tsing Hua University
    Inventors: Wei-Chung Wang, Chi-Hung Huang, Po-Chi Sung, Wei-Ren Chen, Guan-Ting Lai
  • Magnetic memory system and methods in various modes of operation
    Patent number: 8780616
    Abstract: A magnetic memory system includes a superconductor circuit and one or more magnetic memory elements to store data. To write data, a driver circuit in the superconductor circuit generates a magnetic signal for transmission over a superconductor link extending between the superconductor circuit and the magnetic memory element. To read data, a sensing circuit in the superconductor circuit monitors a superconductor link extending from sensing circuit to the magnetic memory element. The magnetic memory element can be a spin-transfer type magnetic memory element.
    Type: Grant
    Filed: May 22, 2012
    Date of Patent: July 15, 2014
    Assignees: Raytheon BBN Technologies Corp., New York University
    Inventors: Thomas Akira Ohki, Andrew Kent
  • Programmable robot and user interface
    Patent number: 8779715
    Abstract: A programmable robot system includes a robot provided with a number of individual arm sections, where adjacent sections are interconnected by a joint. The system furthermore includes a controllable drive mechanism provided in at least some of the joints and a control system for controlling the drive mechanism. The robot system is furthermore provided with user a interface mechanism including a mechanism for programming the robot system, the user interface mechanism being either provided externally to the robot, as an integral part of the robot or as a combination hereof, and a storage mechanism co-operating with the user interface mechanism and the control system for storing information related to the movement and further operations of the robot and optionally for storing information relating to the surroundings.
    Type: Grant
    Filed: March 2, 2007
    Date of Patent: July 15, 2014
    Assignee: Universal Robots ApS
    Inventors: Kristian Kassow, Esben Hallundbæk Østergaard, Kasper Støy
  • SiRNA-mediated gene silencing
    Patent number: 8779116
    Abstract: The present invention is directed to small interfering RNA molecules (siRNA) targeted against an allele of interest, and methods of using these siRNA molecules.
    Type: Grant
    Filed: November 5, 2012
    Date of Patent: July 15, 2014
    Assignee: University of Iowa Research Foundation
    Inventors: Beverly L. Davidson, Henry Paulson, Victor Miller, Cynthia Gouvion
  • Current-mode CMOS logarithmic function circuit
    Patent number: 8779833
    Abstract: The current-mode CMOS logarithmic function circuit provides an ultra-low power circuit that produces an output current proportional to the logarithm of the input current. An OTA (operational transconductance amplifier) constructed from CMOS transistors, in combination with two PMOS transistors configured in weak inversion mode for providing a reference voltage input and a voltage input from the input current to the OTA, provides the circuit with a high dynamic range, controllable amplitude, high accuracy, and insensitivity to temperature variation.
    Type: Grant
    Filed: March 12, 2012
    Date of Patent: July 15, 2014
    Assignee: King Fahd University of Petroleum and Minearals
    Inventors: Karama M. Al-Tamimi, Munir Ahmed Al-Absi
  • Method of treatment using ?-1-adrenergic agonist compounds
    Patent number: 8778897
    Abstract: Methods for treating or preventing cardiomyopathy in a subject by administering an ?1 adrenergic receptor agonist, wherein the treatment does not result in increased blood pressure are provided.
    Type: Grant
    Filed: September 7, 2012
    Date of Patent: July 15, 2014
    Assignee: The Regents of the University of California
    Inventor: Paul C. Simpson, Jr.
  • Game betting device
    Patent number: 8777730
    Abstract: The present application provides a game betting device, wherein each of antennas 21 belongs both two major groups, the major groups are further classified into a plurality of small groups, two major groups have different classifications of the small groups from each other, and at least one column or at least one row in the alignment of the betting regions includes a plurality of small groups included in an identical major group in a single column or row. The game betting device according to the present application makes it possible to read out a chip on a betting board in a short time.
    Type: Grant
    Filed: June 22, 2010
    Date of Patent: July 15, 2014
    Assignee: Universal Entertainment Corporation
    Inventor: Toshimi Koyama
  • Anatomically customized and mobilizing external support, method for manufacture
    Patent number: 8777946
    Abstract: The present invention relates to an anatomically personalized and mobilizing external support, a method for manufacturing is, as well as the use of a component of an invasively attached external support in determining the path of the joint being supported. In the method according to the invention, the kinetic dynamics of the joint are measured with the aid of a component of an external support invasively attached to two bone groups, on the basis of which an external support is arranged between the bone groups.
    Type: Grant
    Filed: September 30, 2010
    Date of Patent: July 15, 2014
    Assignee: Aalto University Foundation
    Inventors: Jan Erik Lindahl, Jari Salo, Jukka Tuomi, Roy Björkstrand, Kaija-Stlina Paloheimo
  • Tunable polish rates by varying dissolved oxygen content
    Patent number: 8778203
    Abstract: A method and system for tunable removal rates and selectivity of materials during chemical-mechanical polishing using a chemical slurry or solution with increased dissolved oxygen content. The slurry can optionally include additives to improve removal rate and/or selectivity. Further selectivity can be obtained by varying the concentration and type of abrasives in the slurry, using lower operating pressure, using different pads, or using other additives in the dispersion at specific pH values.
    Type: Grant
    Filed: May 31, 2011
    Date of Patent: July 15, 2014
    Assignee: Clarkson University
    Inventors: P. R. Veera Dandu, Naresh K. Penta, Babu V. Suryadevara, Uma Rames Krishna Lagudu