Abstract: An apparatus comprising a crank-slider linkage and a rocker link. The crank-slider linkage has a crank coupled to the slider by a jointed connecting rod. The jointed connecting rod has a first link and a second link. The first link is coupled to the second link by a first revolute joint. The first link is coupled to the crank and has a longitudinal axis. The rocker link has a rocker end and a ground end. The rocker end is coupled to the jointed connecting rod. The ground end is coupled to ground by a second revolute joint. The rocker link and the second link are disposed on a common side of the longitudinal axis.

Abstract: Synthesis of platinum(II) di(2-pyrazolyl)benzene chloride and analogs includes forming a 1,3-di-substituted benzene including two aromatic five-membered heterocycles, and reacting the 1,3-di-substituted benzene with an acidic platinum-containing solution to form a luminescent platinum(II) complex. The luminescent platinum(II) complex is capable of emitting blue and white light and can be used as an emitter in a light emitting device.

Abstract: A direct double-frequency ripple current control in a two-stage high-frequency-link (HFL) based fuel cell converter that can achieve low-frequency ripple free input current without using large electrolytic capacitors is provided. To eliminate the double-frequency ripple current disturbance introduced by the single-phase inverter load, a proportional-resonant (PR) controller is developed to achieve an extra high control gain at designed resonant frequency. This high gain can be viewed as the virtual high impedance for blocking the double-frequency ripple energy propagation from inverter load to fuel cell stack. More particularly, the proposed control system can realize the utilization of all capacitive ripple energy sources in the system by regulating all the capacitors to have large voltage swing and the voltage swing is synchronized to keep real-time balancing of the transformer primary-side and secondary-side voltages.

Abstract: An example system and method of processing cardiac activation information are disclosed. The method includes accessing a first cardiac signal and a second cardiac signal obtained from a patient. The first cardiac signal and the second cardiac signal are processed to determine whether there is a point of change in the first cardiac signal at which a derivative of the first cardiac signal diverges with respect to a derivative of the second cardiac signal above a threshold. An activation onset time is assigned in the first cardiac signal at the point of change to define a cardiac activation if the point of change is in the first cardiac signal.

Abstract: The invention provides virus-like particles (VLP) highly secreting or producing signal peptide obtained by altering a signal sequence derived from West Nile virus (WNV), the signal peptide, a WNV VLP secretion expression vector containing a nucleic acid encoding prM protein and E protein, a WNP VLP highly secreting or producing animal cell line harboring the vector, a WNV vaccine containing WNV VLP obtained by the cell line as an active ingredient, and a WNV DNA vaccine containing the VLP secretion expression vector as an active ingredient.

Abstract: In one aspect, the subject matter disclosed herein is directed to NO-releasing functionalized nanorods having a desirable aspect ratio. The nanorods are also capable of releasing a desirable amount of NO (nitric oxide). In another aspect, the subject matter disclosed herein is directed to a composition comprising the NO-releasing nanorods. In another aspect, the subject matter disclosed herein is directed to methods of preparing NO-releasing nanorods having a specified aspect ratio. In another aspect, the subject matter disclosed herein is directed to a method of combating infection comprising administering to a subject a composition comprising NO-releasing nanorods, wherein the nanorods have a specified aspect ratio and NO-release profile.

Abstract: A method of determining the susceptibility of a cancer in a subject to treatment with an antimetabolite includes obtaining a sample of cancer cells from the subject, measuring the level of UDG expression in the cancer cells, and comparing the measured levels of UDG expression in the cancer cells to a control level.

Abstract: This invention relates to methods and devices for clock offset and skew estimation. The invention has particular application in the alignment of slave clocks to a master clock. In embodiments of the invention, the slave clock employs an independent free running clock and a recursive estimation technique to estimate the clock offset and clock skew between the slave and master clocks. The slave can then use the offset and skew to correct the free running clock to reflect an accurate image of the master clock.

Abstract: A closure device for closing a bodily passageway is provided. The device includes first and second frames and first and second crossbars. A sheet of biocompatible material is attached to one or more of the frames. The first crossbar extends across the first frame and has terminal crossbar ends connectively linked to separate sites on the first frame; the second crossbar is similarly linked to the second frame. The crossbars are attached to each other at a connection point, and they are each configured to bend away from the connection point when the closure device is deployed to close a bodily passageway. A method of making the closure device is provided, as well as a method for closing a bodily passageway using such a device. Further, a closure device assembly is provided, including a closure device, a delivery catheter housing, and a delivery release member.

Abstract: An apparatus and a method edit an image in a portable terminal, with the method including displaying one or more icons indicating stylus pen functions; when a highlighter icon corresponding to a highlighter function is selected among the displayed icons, displaying a text selected by a stylus pen in an image in a preset fluorescent color; and storing the displayed text in accordance with the fluorescent color.

Abstract: There is set forth herein a sensor for sensing of substances. The sensor can include a sensing crystal oscillator and a reference crystal oscillator. The sensing crystal oscillator and the reference crystal oscillator can be arranged in a phase locked loop so that the oscillators oscillate at a common frequency. The sensor can be configured so that there is a baseline phase differential between the oscillation frequencies of the sensing crystal oscillator and the reference crystal oscillator. Detectable substances accumulating on the sensing crystal oscillator will induce a phase shift between output frequencies of the reference oscillator and the sensing crystal oscillator to allow for highly sensitive sensing of substances in small concentrations.

Abstract: In some embodiments, a system and method for estimating the geographical location at which image data was captured with a camera identifies matching feature points between the captured images, estimates a pose of the camera during the image capture from the feature points, performs geometric reconstruction of a scene in the images using the estimated pose of the camera to obtain a reconstructed scene, and compares the reconstructed scene to overhead images of known geographical origin to identify potential matches

Abstract: Compositions and methods for stimulating an immune response against a secreted enterohemorragic Escherichia coli (EHEC) antigen are disclosed. The compositions comprise EHEC cell culture supernatants.

Abstract: A method for managing consumption of heterogeneous resources includes: receiving resource consumption information of a target; calculating a total energy consumption value that is associated with the target based on the resource consumption information of the target; generating a high consumption alert when the calculated total energy consumption value is higher than a first predetermined threshold value; and generating a low consumption alert when the calculated total energy consumption value is not higher than a second predetermined threshold value that is lower than the first predetermined threshold value.

Abstract: A sodium-ion electrochemical cell described herein comprises a cathode, an anode, and a non-aqueous sodium-containing electrolyte therebetween. The electrolyte comprises a sodium salt dissolved in a liquid organic carrier. The cathode comprises at least one transition metal chalcogenide compound in an initial discharged or partially discharged state and having the formula NaxMX2Cln, wherein 0<x?1; M is at least one transition metal having a +3, +4, or +5 fully discharged oxidation state, i.e., when x is 1. X is at least one chalcogen selected from the group consisting of S and Se, and n is 0 when the discharged oxidation state of M is +3, n is 1 when the discharged oxidation state of M is +4, and n is 2 when the discharged oxidation state of M is +5. In some embodiments, the cathode comprises NaxVS2, NaxTiS2, or a combination thereof.

Abstract: Described herein are polypeptides that home to developing microvasculature, (also referred to as developing microvessels), such as newly developing microvasculature in mammals, particularly in humans, and to DNA that encodes such polypeptides. These polypeptides are referred to herein as developing microvasculature homing polypeptides. In a specific embodiment, the homing peptides are collateral vessel endothelia (CVE) homing polypeptides, which have been shown to home to collateral vessel endothelia after ischemia.

Abstract: In one embodiment, a catalyst for ozone oxidation of pollutant components dispersed in a gas is provided. The ozone oxidation catalyst has a porous body formed from a metal body, a ceramic, or polymeric fibers coated with metal. A catalytic noble metal composition is deposited on the surface of the porous body. The catalytic noble metal composition is formed from particles of a noble metal supported by a mesoporous molecular sieve.

Abstract: A method for diagnosing the presence of hereditary spastic paraplegia (HSP) or predicting the risk of developing HSP in a human subject, comprising detecting the presence or absence of a defect in a gene encoding a polypeptide comprising the sequence of FIG. 9 (SEQ ID NO: 19), in a nucleic acid sample of the subject, whereby the detection of the defect is indicative that the subject has or is at risk of developing HSP.

Abstract: A controlling device such as a remote control has programming for transmitting a signal response to a plurality of control environments, each environment including a signaling device. Each signaling device in receipt of the signal request sends a signal response having a unique ID which is chosen to be characteristically attenuated by the surroundings of the environment. Because the controlling device can only be in one environment at a given time, and given the attenuation characteristics of the signal response from each signaling device, only one signal response will be received by the controlling device in each environment. Location definitions associated with the received unique ID may be used by programming in the controlling device to recall saved devices states, commands sets, macros, and even to dynamically generate commands based on the location information.

Abstract: The invention provides isolated nucleic acid and amino acid sequences of sensory cell specific G-protein coupled receptors, antibodies to such receptors, methods of detecting such nucleic acids and receptors, and methods of screening for modulators of sensory cell specific G-protein coupled receptors.