Patents Assigned to University
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Publication number: 20100192215Abstract: The present invention relates to a method for multi-core processor based packet classification on multiple fields. The first step involved in this invention involves constructing a data structure of classification, which includes selecting a certain dimension such that the sum of the rules that fall into two rule sub-sets of two subspaces is as small as possible after spatial partition through a certain partition point in which the method to determine the partition point on the selected dimension is to select the partition point on the dimension such that the number of rules that fall into the two sub-spaces after partition by the point is equal to each other as much as possible. The invention specifically proposes three methods to select partition points, two associated methods to select dimensions, then receiving packet information after the data structure of classification is constructed, and searching the data structure of classification according to packet information to get matched results.Type: ApplicationFiled: January 19, 2010Publication date: July 29, 2010Applicant: Tsinghua UniversityInventors: Qi Yaxuan, Li Jun
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Publication number: 20100190189Abstract: The invention develops a high-throughput screening method based on charcoal-sorbent peptide binding assay (CPBA) which does not need a solid phase and can simultaneously detect plural target biomolecules in a sample. The method of the invention can achieve high-throughput screening of biomolecules (such as antibodies and antigens) with a molecular weight of more than 10 KD.Type: ApplicationFiled: January 23, 2009Publication date: July 29, 2010Applicant: Taipei Medical UniversityInventors: Yu-Wei Wu, Yu-Hui Tsai
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Publication number: 20100191174Abstract: Apparatuses and methods for the safe and efficient electrical stimulation of tissue. The apparatuses of the present invention are preferably hand-held and are capable of providing electrical waveforms that are effective in promoting wound healing, improving circulation, stimulating peripheral nerves, administering pharmaceutical compounds via electrophoresis, and electroporating DNA into tissue. The present invention also generally contemplates the safe and efficient transfection of DNA into mammalian tissue via electroporation. Particularly, apparatuses of the present invention are useful in the delivery of DNA vaccines and in gene therapy. The present invention also preferably provides for the direct measurement of in vivo tissue resistance. Tissue resistance measurements may then be used to adjust stimulation intensity during electroporation or electrostimulation, so as to avoid damaging tissue during operation of the unit.Type: ApplicationFiled: April 2, 2010Publication date: July 29, 2010Applicant: University of Pittsburgh of The Commonwealth System of Higher EducationInventors: Michael Lovell, Marlin H. Mickle
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Publication number: 20100189025Abstract: The invention is directed to a method for receiving a feedback for at least a multicast broadcast service flow transmitting to a plurality of subscriber stations. The method comprises steps of assigning a plurality of code division multiple access (CDMA) codes to a feedback corresponding to the multicast broadcast service flow and then performing an allocation process for allocating a feedback channel for the subscriber stations. Thereafter, an announcement process is performed to announce a multiple feedback condition, the CDMA codes and the feedback channel to the subscriber stations. A channel monitoring process is performed for receiving a negative-acknowledgment (NACK)-based feedback sending from one of the subscriber stations unsatisfied with the multiple feedback condition and the NACK-based feedback is in a form of one of CDMA codes corresponding to the multicast broadcast service flow and is transmitted through the feedback channel.Type: ApplicationFiled: January 23, 2009Publication date: July 29, 2010Applicant: National Taiwan University of Science and TechnologyInventor: Ray-Guang Cheng
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Publication number: 20100190865Abstract: The invention provides in part dialkoxybenzene and eugenol compounds for controlling infestation by a Lymantria dispar, and methods thereof. The compounds include a compound of Formula I: where R1 may be methyl, ethyl, propyl, n-butyl, isopentyl (3-methylbutyl) or allyl; R2 may be at positions 2, 3 or 4 and may be H, methyl, ethyl, propyl, n-butyl, isopentyl (3-methylbutyl) or allyl; and R3 may be optionally present at positions 2, 3 and 4, and is allyl; with the provisos that when R2 is at position 2, R3 if present is at position 3, or when R2 is at to position 3, R3 if present is at positions 2 or 4, or when R2 is at position 4, R3 if present is at position 2; or of Formula II: where R1 may be methyl, ethyl, propyl, n-butyl, isopentyl (3-methylbutyl) or allyl; or mixtures thereof.Type: ApplicationFiled: November 19, 2009Publication date: July 29, 2010Applicant: Simon Fraser UniversityInventors: Erika Plettner, Yongmei Gong, Regine Gries
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Publication number: 20100187106Abstract: A portable, lightweight, rugged, easy-to-operate biosensor useful for rapidly detecting cells, viruses, antibodies, and other proteins. A capillary tube has a capture antibody immobilized on its interior surface. The specific capture antibody is selected based upon a desired target analyte to be detected. A sample potentially containing the target antigen is introduced into the capillary tube. Thereafter, a second antibody labeled with a fluorescent dye is introduced. Upon excitation by electromagnetic energy, typically supplied by a laser, the fluorescence of the sample is captured and analyzed. The apparatus is extremely compact and rugged making it ideal for field use. In addition, accurate results may be obtained by relatively unskilled operators directly from a self-contained readout. Optionally, an external device (e.g., a computer) may be connected to the apparatus via an optional interface.Type: ApplicationFiled: April 7, 2010Publication date: July 29, 2010Applicant: Research Foundation of State University of New YorkInventors: Omowunmi SADIK, Jason KARASINSKI
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Publication number: 20100190260Abstract: A method for quantifying the presence of naphthenic acids in a hydrocarbon-comprising liquid that includes: contacting a hydrocarbon-comprising liquid with gaseous ammonia; isolating a reaction product produced by the contacting step; and analyzing the reaction product for the presence of naphthenates using a mass spectrometry technique. The naphthenic acids known to form commercial naphthenate deposits can be (i) ions of tetraprotic carboxylic acids having molecular weights ranging from 1225 to 1270 Daltons, (ii) n-alkyl or branched carboxylic acids having molecular weights ranging from 250 to 650 Daltons, or (iii) both.Type: ApplicationFiled: January 27, 2010Publication date: July 29, 2010Applicant: Florida State UniversityInventors: Alan G. Marshall, Priyanka Juyal, Mmilili M. Mapolelo, Ryan P. Rodgers
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POLYPEPTIDES WITH ENHANCED ANTI-INFLAMMATORY AND DECREASED CYTOTOXIC PROPERTIES AND RELATING METHODS
Publication number: 20100189714Abstract: The invention provides a polypeptide containing at least one IgG Fc region, wherein said at least one IgG Fc region is glycosylated with at least one galactose moiety connected to a respective terminal sialic acid moiety by a ? 2, 6 linkage, and wherein said polypeptide having a higher anti-inflammatory activity as compared to an unpurified antibody.Type: ApplicationFiled: July 3, 2007Publication date: July 29, 2010Applicant: The Rockefeller UniversityInventors: Jeffrey V. Ravetch, Falk Nimmerjahn, Yoshikatsu Kaneko -
Publication number: 20100190153Abstract: Modulation of the viscosity of the oil phase of a microemulsion used for amplification of DNA on a bead increases the homogeneity of product beads and the amount of amplified DNA per bead. Moreover the number of separate microemulsion populations that can be formed in parallel is increased using multi-well plates and mixer mill disruptor machines designed to lyse biological samples.Type: ApplicationFiled: June 19, 2007Publication date: July 29, 2010Applicant: The Johns Hopkins UniversityInventors: Frank Diehl, Kenneth W. Kinzler, Bert Vogelstein
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Publication number: 20100190702Abstract: The invention features compositions and methods that are useful for the treatment of neoplasia by reducing base excision repair (BER). Such compositions are useful, for example, for enhancing the efficacy of known chemotherapeutics, such as DNA alkylating agents. In particular, the invention features agents that mimic the interaction of APC with pol-?. Such agents reduce the activity of long patch- and single nucleotide-base extension repair pathways.Type: ApplicationFiled: February 14, 2008Publication date: July 29, 2010Applicant: University of Florida Research FoundationInventors: Satya Narayan, Aruna S. Jaiswal, David A. Ostrov
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Publication number: 20100191116Abstract: The invention relates to a method for quantification of a degree of obstruction in a liquid passageway, notably a male urethra. Data related to sonic waves generated by a liquid passing the obstruction may be accessed from a suitable file, or, alternatively may be directly obtained as a result of a measuring step 2. For determining the degree of obstruction of the urethra the measuring step 2 may be performed by arranging at least one sensor, notably a microphone, in the area of the perineum for detecting sonic waves generated by a liquid (urine) passing the obstruction. At the step 5 the power spectrum of the obtained data related to the sonic waves is calculated, after which a suitable feature 6a, 6b, or 6c representative of the power spectrum is selected. Preferable embodiments of the feature comprise a weighted average frequency of the power spectrum, a standard deviation of the power spectrum, or a skewness of the power spectrum, discussed above.Type: ApplicationFiled: June 16, 2008Publication date: July 29, 2010Applicants: Stichting Voor de Technische Wetenschappen, Erasmus University Medical Center RotterdamInventors: Tim Idzenga, Johannes Jacob Mient Pel, Robert van Mastrigt
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Publication number: 20100189794Abstract: Methods and compositions are provided for producing nucleic acid-based compositions. Methods include enzyme catalyzed or nucleic acid polymer conjugation. Compositions include nucleic acid-containing hydrogels which can be elongated via rolling circle amplification. The hydrogels can encapsulate bioactive agents for drug delivery.Type: ApplicationFiled: January 5, 2010Publication date: July 29, 2010Applicant: Cornell UniversityInventors: Dan Luo, Jong Bum Lee, Hisakage Funabashi
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Publication number: 20100190187Abstract: Various embodiments of the present invention provide methods for screening for candidate heart failure compounds employing screening assays effective in identifying agonists or antagonists or ligands of vitamin D receptor mediated pathways implicated in heart failure. Methods are provided for the screening of test compounds that can specifically bind to the vitamin D receptor. Methods for screening for a test compound which modulates the activity of a VDR for the treatment of heart failure, wherein the method comprises: (a) contacting a test compound with VDR in a reaction mixture, wherein the reaction mixture conditions permits the test compound to bind to a VDR, including membrane VDR and nuclear VDR. The binding between the test compound and the VDR is compared to a reference such as Vitamin D3. The modulation of biomarkers after a test compound has bound and activated a VDR are also measured and compared to samples in the absence of test compound.Type: ApplicationFiled: February 14, 2007Publication date: July 29, 2010Applicant: The Regents of the University of Michigan Office of Technology TransferInventors: Robert U. Simpson, Daniel Tishkoff, Karl Nibbelink
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Publication number: 20100190729Abstract: The present invention relates to a composition for treating atopic dermatitis comprising hirsutanonol as an active ingredient. Hirsutanonol or oregonin as the active ingredient of the present composition decreases the number of eosinophil increased in atopic dermatitis and regulates expression amounts of immune regulatory cytokines, IL-4, IL-5, IL-10 and IL-13 associated with atopic dermatitis. In addition, hirsutanonol and oregonin increase MBD (mouse beta-defensin)-1, MBD-2 and MBD-3 expression and decrease COX-2 and iNOS expression in mouse animal model of atopic dermatitis. Hirsutanonol and oregonin as the active ingredient of the present composition could be effectively used in drugs, cosmetics and foods for treating atopic dermatitis.Type: ApplicationFiled: May 19, 2009Publication date: July 29, 2010Applicant: CHUNG-ANG University Industry Academic Cooperation FoundationInventors: Min Won Lee, Young Wook Choi, Seong Jun Seo, Do Ik Lee, Hyoweon Bang, Chung Soo Lee, Jong Chan Lee, Soon-Chul Myung, Mi-Kyung Lee, Seong Soo Joo, Sun Eun Choi
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Publication number: 20100189913Abstract: A rolling contact layer-by-layer assembly device comprises at least one roller, a cylinder substrate and a motor to rotate the cylinder substrate. The assembly device optionally includes at least one rinsing nozzle and air applicator. The rollers each provide a polyelectrolyte solution to the surface of the cylinder substrate, the polyelectrolyte solutions having an affinity for each other. Excess polyelectrolyte solution can be washed using the rinsing nozzle followed by a drying step prior to the application of the second polyelectrolyte solution. A plurality of bilayers is produced by the continuous application of polyelectrolyte solutions to form an LBL article such as a nano-composite article or film. The film is then removed from the surface of the cylinder substrate.Type: ApplicationFiled: December 3, 2009Publication date: July 29, 2010Applicant: The Regents of the University of Michigan Office of Technology TransferInventors: Nicholas Kotov, Javier Canavati Leal, Justin Lefevre, Neil H. Patel, Brett M. Perry, Anastasios J. Hart
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Publication number: 20100190699Abstract: Modified glucagon peptides are disclosed having improved solubility while retaining glucagon agonist activity. The glycogen peptides have been modified by substitution of native amino acids with, and/or addition of, charged amino acids to the carboxy terminus of the peptide. The modified glucagon agonists can be further modified by pegylation, or the addition of a carboxy terminal peptide selected from the group consisting of SEQ ID NO: 20, SEQ ID NO: 21, SEQ ID NO: 23, or both to further enhance the solubility of the glucagon agonist analogs.Type: ApplicationFiled: January 3, 2008Publication date: July 29, 2010Applicant: Indiana University Research and Technology CorporationInventors: Richard D. Dimarchi, Maria Dimarchi, Joseph Chabenne
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Publication number: 20100188186Abstract: A soft magnetic amorphous alloy represented by the following composition formula: {Fea(SixByPz)1-a}100-bLb. In the composition formula, L represents one or more elements selected from Al, Cr, Zr, Nb, No, Hf, Ta and W, and a, b, x, y, and z meets the conditions of: 0.7?a?0.82; 0?b?5 atomic %; 0.05?x?0.6; 0.1?y?0.85; 0.05?z?0.7; and x+y+z=1.Type: ApplicationFiled: September 16, 2008Publication date: July 29, 2010Applicants: NEC Tokin Corporation, Tohoku UniversityInventors: Akiri Urata, Hiroyuki Matsumoto, Akihiro Makino
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Publication number: 20100190686Abstract: The present invention relates to the discovery of polypeptide biomarkers excreted into the blood stream (serum or plasma) and/or urine from adipocytes and their use to determine the existence of metabolic syndrome (prediabetic) and/or diabetic conditions (including type 2 diabetes) including insulin resistance and/or glucose intolerance, their use to monitor the state of metabolic syndrome or diabetes toward a state of control and/or cure of the disease state or condition and their use to monitor the long-term health of the patient by determining the existence of metabolic syndrome (prediabetic conditions insulin resistance and/or glucose intolerance) or the existence of type 2 diabetes and to identify potential antidiabetes agents. Methods of identifying potential agents to be used in the treatment of metabolic syndrome and/or type2 diabetes and assays for assisting in the diagnosis of metabolic syndrome and/or type 2 diabetes are additional aspects of the invention.Type: ApplicationFiled: June 23, 2008Publication date: July 29, 2010Applicant: The University of Georgia Research FoundationInventors: Robert L. Wells, Jae-min Lin, Dorothy Hausman
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Publication number: 20100190270Abstract: Systems and methods for detecting a gaseous analyte utilize a micromechanical piezoelectric resonator having a functionalization layer configured to bind with the gaseous analyte. The functionalization layer may include a layer of carbon nanotubes affixed to the resonator and coated with biopolymers configured to bind with the gaseous analyte. The gaseous analyte may be detected by operating the micromechanical piezoelectric resonator and functionalization layer in the presence of the gas, detecting a change in the resonant frequency of the resonator, and determining the concentration of the gaseous analyte from the change in resonant frequency. Finally, the layer of carbon nanotubes may be grown on the piezoelectric resonator by depositing a catalyst on a piezoelectric structure, heating the piezoelectric structure and the catalyst to enhance the growth of the carbon nanotubes, and growing the carbon nanotubes at growth sites on the piezoelectric structure.Type: ApplicationFiled: January 25, 2010Publication date: July 29, 2010Applicant: The Trustees of the University of PennsylvaniaInventors: Gianluca Piazza, Alan T. Johnson, Matteo Rinaldi, Chiara Zuniga
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Publication number: 20100186665Abstract: The present invention involves a method and apparatus for depositing a silicon oxide onto a substrate from solution at low temperatures in a manner that produces homogeneous growth of the silicon oxide. The method generally comprises the following steps: (a) Chemically treating a substrate to activate it for growth of the silicon oxide. (b) Immersing the treated substrate into a bath with a reactive solution. (c) Regenerating the reactive solution to allow for continued growth of the silicon oxide. In another embodiment of the present invention, the apparatus includes a first container holding a reactive solution, a substrate on which the silicon oxide is deposited, a second container holding silica, and a means for adding silica to the reactive solution.Type: ApplicationFiled: March 31, 2010Publication date: July 29, 2010Applicant: William Marsh Rice UniversityInventors: Andrew R. Barron, Elizabeth Anne Whitsitt