Abstract: This invention relates to protein engineering technology. More particularly, the present invention relates to a method for preparing human IgE antibodies and derivatives thereof, which bind epitope structures that are weakly IgG or IgM immunoreactive.

Abstract: An optical radiation processing unit directs different wavelengths of the optical radiation emitted by an optical source to an object being measured from a direction that differs from the normal of a surface being measured so that the different wavelengths focus on different heights in the direction of the normal of the surface. A possible polarizer polarizes the reflected radiation in a direction perpendicular to the normal of the surface. The optical radiation processing unit directs to a detector polarized optical radiation that received from the object. The signal processing unit determines on the basis of a signal provided by the detector from the detected radiation the wavelength on which radiation is the highest, and determines the location of the surface by the determined wavelength. When measuring an object from both sides, the thickness of the object being measured is determinable using the locations of the surfaces.

Abstract: An apparatus, and a method, comprising: computing a measure of goodness for each of at least two dimensions of a system linked to a first state of the system and a second state of the system; computing a weighting for each of at least two dimensions linked to a studied system, the weightings describing the differences of said at least two dimensions in relation to said first state and said second state; and inferring the state of the studied system based on said measures of goodness and said weightings.

Abstract: An optical or infrared spectrometer is suitable for on-line measurements for industrial, agricultural, field, commercial and other applications. Optical spectrometers are very useful for various analytical measurements. On-line operation is needed for obtaining real-time information, which is useful e.g. for process automation and quality control needs. The invention is based on optical design optimized for measuring moving samples at a distance and includes a light guide for signal homogenization, a linear variable filter for defining multiple measurement wavelengths as well as a linear detector array for detecting optical signals relating to the different wavelengths. There is an element for cooling and stabilizing the operating temperature of both the linear detector array and the linear variable filter, while the spectrometer is operating in variable environmental conditions.

Abstract: The invention relates to an apparatus for producing a pyrolysis product, the apparatus comprising a pyrolysis reactor for forming pyrolysis product fractions from raw material by fast pyrolysis, a condensing device for condensing gaseous pyrolysis product fractions to mainly liquid pyrolysis product fractions, a combustion boiler arranged in conjunction with the pyrolysis reactor for forming energy fractions, and feeding devices for feeding raw materials to the pyrolysis reactor and the combustion boiler. According to the invention, the apparatus comprises a separating device arranged substantially in conjunction with the pyrolysis reactor for separating other fractions from the gaseous pyrolysis product fractions after the pyrolysis and means for conducting other fractions than the gaseous pyrolysis product fractions from the separator to the combustion boiler.

Abstract: The invention relates to a spectrometer, a spectrometric method and detector, and a new use of an interferometer. The spectrometer comprises a Fabry-Perot interferometer (120), to which light can be guided from the object (100) being investigated, in order to produce an interference image, and a detector (130) at which the interference image is aimed. The transmittance of the interferometer (120) is spectrally sliced to at least two separate wavelength bands. For its parts, the detector (130) is arranged to detect the interference image from at least two separate wavelength bands spatially. The detector is arranged to detect the said wavelength bands simultaneously, by exploiting the response of the image elements of the detector, calibrated as a function of the mirror gap of the interferometer, in order to detect simultaneously at least two different orders of the interference.

Abstract: A supply air device including supply air nozzles, through which incoming air is led into a mixing chamber and further into a room so that the supply air device induces a circulating or secondary air flow from the room. An electric particle filter and/or a cell gas filter, through which the circulating or secondary air flow is led.

Abstract: The invention relates to a method for treating ERG-positive prostate cancer patients with an agent counteracting one or more ERG-associated genes and/or manipulating of one or more ERG-related pathways, optionally in combination with an androgen deprivation therapy. Furthermore, the invention concerns methods for screening prostate cancer patients which may benefit from said treatment, assessing the efficacy of a therapy for treating prostate cancer in a patient, assessing progression of prostate cancer in a patient, selecting an agent to be tested for usefulness in the treatment of prostate cancer, and for assessing prostate carcinogenic potential of an agent.

Abstract: The invention concerns an ink composition comprising an oxidizing and reducing agent and/or pH colorant as the dye, polymeric material as the binder, as well as a pH adjuster and volatile solvent. Further, the invention concerns a method for manufacturing an oxygen and/or pH indicator, in which the ink composition is printed and reduced, or reduced using a volatile reducer and printed; an oxygen and/or pH indicator manufactured by the method, as well as a package for stating a leakage, a change caused by oxygen content and/or deterioration of a product.

Abstract: A device for producing electric energy including a first element converting mechanical energy into electric energy. The level of the electric energy is variable according to the variations of the mechanical energy. A controller block is connected to the first element for providing measurement data on the basis of the electric energy produced by the first element. The controller block includes a detector block to examine the electric energy produced by the first element to form the measurement data. A first energy storage unit stores electric energy produced by the first element and provides the electric energy for the operation of the controller block. Also, a system, a tire and a method.

Abstract: The present invention relates to polyesterases having cutinase and/or suberinase activity obtainable from Coprinus and Trichoderma. The invention further relates to a method for producing the polyesterases, and to polynucleotides, vectors and host cells used therein. The enzymes are useful in hydrolysing cutin, suberin and other polyesters for example in treating agricultural or food raw materials, or wood raw materials, pulp and paper products and waste, and in modifying polyester fibers, or in laundry and dish applications.

Abstract: The present invention relates to a power feeding arrangement for electric loads (R) positioned in tires (20) of vehicles. According to the invention the arrangement comprises at least one feed coil (Lf) arranged in the vehicle (10), at least one receiver coil (Lr) arranged in the tire (20), and at least one load (R) electrically coupled to the receiver coil (Lr).

Abstract: The invention relates to compositions of cosmetic and pharmaceutical industries comprising betulonic acid for humans and animals, and further, to the use of betulonic acid in compositions of cosmetic and pharmaceutical industries. The invention is also directed to compositions containing, besides betulonic acid, optionally other compounds derived from betulin.

Abstract: The invention relates to betulin derivatives, and to the use thereof as agents against protozoa of the genus Leishmania and against leishmaniasis in applications of pharmaceutical industry.

Abstract: This publication discloses a method for forming electrically conducting structures on a substrate. According to the method nanoparticles containing conducting or semiconducting material are applied on the substrate in a dense formation and a voltage is applied over the nanoparticles so as to at least locally increase the conductivity of the formation. According to the invention, the voltage is high enough to cause melting of the nanoparticles in a breakthrough-like manner. With the aid of the invention, small-linewidth structures can be created without high-precision lithography.

Abstract: A process for producing ethanol from a fibrous lignocellulosic raw material. After pre-treatment of the raw material, the fibrous fraction is first hydrolysed at high consistency and then the modified material is subjected simultaneously to continued hydrolysis with a cellulase and to ethanol fermentation in a fermentation mixture. Fermentation is continued to convert an essential portion of the available cellulose into ethanol, then a liquid fraction containing solubilized hemicelluloses is added to the fermentation mixture and fermentation continued. By means of the invention, high fermentation rates, high ethanol concentrations and low ethanol production costs can be attained.

Abstract: A non-competitive immunoassay for small analytes, wherein the analyte is reacted with two binding partners. The first binding partner binds to the analyte to form a complex between the first binding partner and the analyte, and the second binding partner binds to the complex formed by the first binding partner and the analyte. The resulting complex formed between the analyte and the binding partners is detected. The binding partners are proteins, such as antibodies including antibody fragments.

Abstract: The invention concerns a method for inhibiting vascular endothelial growth factor receptor 2 (VEGFR2) signalling in an individual by administering an effective amount of an agent capable of activating T cell protein tyrosine phosphatase (TCPTP), and a method for inhibiting angiogenesis and treating or preventing diseases related thereto. Furthermore, this invention concerns a method for stimulating angiogenesis or for treatment or prevention of a disease benefiting from increasing the growth of blood vessels in an individual by inhibiting TCPTP.

Abstract: The invention relates to an antenna construction for a double-ended antenna circuit 4. The antenna construction comprises a conductive ground place (6) on a first surface, a transmission line (3) on at least one second surface, connected to the ground plane (6) through a fold (1) in the edge of the antenna construction, so that the fold acts as a primary source of a magnetic field, an insulation layer (7) arranged between the first and the second surfaces, and an electronic component (4), in which there is a double-ended antenna connector, connected to the antenna construction. According to the invention, the electronic component (4) is attached to the second surface of the antenna construction and connected from the first antenna terminal to the transmission line (3) and from the second terminal to either a second transmission line (3) or the fold (1).

Abstract: A method, apparatus, system, and computer program for analyzing properties of an application-specific end-to-end communication connection are presented. In a connection performance analysis apparatus, measurement data messages are received from a plurality of traffic-monitoring nodes arranged at selected intermediate points in a plurality of network segments of the application-specific end-to-end communication connection and from at least one end node of the end-to-end communication connection, wherein a measurement data message comprises information related to a travel time of at least one data packet of the end-to-end communication connection to the traffic-monitoring node or to the end node transmitting the respective measurement data message. Then, the connection performance analysis apparatus analyzes the received measurement data messages in order to determine a bottleneck of the end-to-end communication connection.