Patents Assigned to Vestaron Corporation
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Publication number: 20240041038Abstract: New insecticidal combinations, compositions, and methods of using the same are provided. The present invention is directed to combinations of Cysteine Rich Insecticidal Peptides (CRIPS), and Insecticidal Agents (IAs). The present invention also describes the use of said combinations and compositions for the control of insects. Here, we describe the following: genes encoding CRIPs; compositions and combinations comprising CRIPs and IAs; and methods using the same that are useful for the control of pests.Type: ApplicationFiled: April 30, 2021Publication date: February 8, 2024Applicant: Vestaron CorporationInventors: Kyle SCHNEIDER, Breck DAVIS, Daniel HULBERT, Joseph TOURTOIS
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Publication number: 20240018198Abstract: New insecticidal peptides, polypeptides, proteins, and nucleotides; their expression in culture and plants; methods of producing the peptides, polypeptides, proteins, and nucleotides; new processes; new production techniques; new formulations; and new organisms, are disclosed. The present disclosure is also related to a novel type of peptide named Dc1a-Variant Polypeptides (DVPs) that are a non-naturally occurring, modified-form of the peptide, Mu-diguetoxin-Dc1a, isolated from the American Desert Spider (Diguetia canities). Here we describe: genes encoding DVPs; various formulations and combinations of both genes and peptides; and methods for using the same that are useful for the control of insects. Further, the present invention relates to novel, recombinant cysteine rich proteins (CRPs) with a cystine knot (CK) architecture, created by removing one or more disulfide bonds from a polypeptide having four or more disulfide bonds.Type: ApplicationFiled: September 27, 2021Publication date: January 18, 2024Applicant: Vestaron CorporationInventors: Kyle SCHNEIDER, Alexandra HAASE, Breck DAVIS
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Publication number: 20230337684Abstract: New insecticidal proteins, nucleotides, peptides, and their expression in plants. Methods of producing new nucleotides and new peptides, new processes, new production techniques, new formulations, and new organisms. The present disclosure is also related to and describes novel peptides called TVPs, which are non-natural peptide variations based upon the U1-agatoxin-Ta1b toxin derived from the Hobo spider. Here, we describe: genes encoding TVPs; formulations and combinations comprising TVP genes and/or peptides; and methods using the same that are useful for the control of pests.Type: ApplicationFiled: April 20, 2021Publication date: October 26, 2023Applicant: Vestaron CorporationInventors: Kyle SCHNEIDER, Alexandra HAASE, Breck DAVIS, Ryan GARRETT
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Publication number: 20230257427Abstract: New insecticidal proteins, nucleotides, peptides, their expression in plants, methods of producing the peptides, new processes, production techniques, new peptides, new formulations, and new organisms, a process which increases the insecticidal peptide production yield from yeast expression systems. The present invention is also related and discloses selected endotoxins we call cysteine rich insecticidal peptides (CRIPS) which are peptides derived from Bacillus thuringiensis (Bt) and their genes and endotoxins in combination with toxic peptides known as Inhibitor Cystine Knot (ICK) genes and peptides as well as with other types of insecticidal peptides such as trypsin modulating oostatic factor (TMOF) peptide sequences used in various formulations and combinations; of both genes and peptides, useful for the control of insects.Type: ApplicationFiled: September 8, 2022Publication date: August 17, 2023Applicant: Vestaron CorporationInventors: Robert M. KENNEDY, William Tedford, Christopher Hendrickson, Robert Venable, Catherine L. Foune, John Mcintyre, Alvar R. Carlson, Lin Bao
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Patent number: 11713341Abstract: Engineered, non-naturally occurring antimicrobial NCR13 variant peptides (NVPs), or agriculturally acceptable salts thereof, are described, along with methods of making and using the same. The present disclosure is also related to and describes novel antimicrobial compositions, formulations, and methods of using the same, that are useful for the control of pathogenic microbes.Type: GrantFiled: June 17, 2022Date of Patent: August 1, 2023Assignee: Vestaron CorporationInventor: Lin Bao
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Patent number: 11535653Abstract: A peptide comprised of either a binary or a tertiary peptide, the peptide contains at least 4 amino acids and up to a maximum of 16 amino acids, comprised of 2 or 3 different regions, wherein the binary peptides have 2 different regions and the tertiary peptides have 3 different regions; wherein, the peptide can be cleaved by both an animal gut protease and an insect or nematode gut protease.Type: GrantFiled: October 6, 2017Date of Patent: December 27, 2022Assignee: VESTARON CORPORATIONInventors: Alvar R. Carlson, Alexandra M. Haase, Robert M. Kennedy
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Publication number: 20220380417Abstract: A peptide comprised of either a binary or a tertiary peptide, the peptide contains at least 4 amino acids and up to a maximum of 16 amino acids, comprised of 2 or 3 different regions, wherein the binary peptides have 2 different regions and the tertiary peptides have 3 different regions; wherein, the peptide can be cleaved by both an animal gut protease and an insect or nematode gut protease.Type: ApplicationFiled: August 12, 2022Publication date: December 1, 2022Applicant: Vestaron CorporationInventors: Alvar R. CARLSON, Alexandra M. Haase, Robert M. Kennedy
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Patent number: 11472854Abstract: New insecticidal proteins, nucleotides, peptides, their expression in plants, methods of producing the peptides, new processes, production techniques, new peptides, new formulations, and new organisms, a process which increases the insecticidal peptide production yield from yeast expression systems. The present invention is also related and discloses selected endotoxins we call cysteine rich insecticidal peptides (CRIPS) which are peptides derived from Bacillus thuringiensis (Bt) and their genes and endotoxins in combination with toxic peptides known as Inhibitor Cystine Knot (ICK) genes and peptides as well as with other types of insecticidal peptides such as trypsin modulating oostatic factor (TMOF) peptide sequences used in various formulations and combinations; of both genes and peptides, useful for the control of insects.Type: GrantFiled: May 1, 2020Date of Patent: October 18, 2022Assignee: Vestaron CorporationInventors: Robert M. Kennedy, William Tedford, Christopher Hendrickson, Robert Venable, Catherine L. Foune, John McIntyre, Alvar R. Carlson, Lin Bao
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Patent number: 11447531Abstract: A peptide comprised of either a binary or a tertiary peptide, the peptide contains at least 4 amino acids and up to a maximum of 16 amino acids, comprised of 2 or 3 different regions, wherein the binary peptides have 2 different regions and the tertiary peptides have 3 different regions; wherein, the peptide can be cleaved by both an animal gut protease and an insect or nematode gut protease.Type: GrantFiled: October 6, 2017Date of Patent: September 20, 2022Assignee: Vestaron CorporationInventors: Alvar R. Carlson, Alexandra M. Haase, Robert M. Kennedy
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Publication number: 20220048960Abstract: New insecticidal proteins, nucleotides, peptides, their expression in plants, methods of producing the peptides, new processes, production techniques, new peptides, new formulations, and new organisms, a process which increases the insecticidal peptide production yield from yeast expression systems. The present disclosure is also related and discloses toxins called AVPs, which are modified from the Av3 toxin derived from sea anemone; here we describe the genes encoding the new polypeptide, as well various formulations and combinations; of both genes and peptides, useful for the control of insects.Type: ApplicationFiled: September 13, 2019Publication date: February 17, 2022Applicant: Vestaron CorporationInventors: Robert M. KENNEDY, Lin BAO
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Publication number: 20200277345Abstract: New insecticidal proteins, nucleotides, peptides, their expression in plants, methods of producing the peptides, new processes, production techniques, new peptides, new formulations, and new organisms, a process which increases the insecticidal peptide production yield from yeast expression systems. The present invention is also related and discloses selected endotoxins we call cysteine rich insecticidal peptides (CRIPS) which are peptides derived from Bacillus thuringiensis (Bt) and their genes and endotoxins in combination with toxic peptides known as Inhibitor Cystine Knot (ICK) genes and peptides as well as with other types of insecticidal peptides such as trypsin modulating oostatic factor (TMOF) peptide sequences used in various formulations and combinations; of both genes and peptides, useful for the control of insects.Type: ApplicationFiled: May 1, 2020Publication date: September 3, 2020Applicant: Vestaron CorporationInventors: Robert M. KENNEDY, William TEDFORD, Christopher HENDRICKSON, Robert VENABLE, Catherine L. FOUNE, John MCINTYRE, Alvar R. CARLSON, Lin BAO
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Publication number: 20200255482Abstract: New insecticidal nucleotides, peptides, polypeptides, and proteins, and their expression in plants; methods of producing new peptides; new processes and production techniques; new formulations; new organisms; and a process which increases the insecticidal peptide production yield from yeast expression systems. The present invention is also directed to insecticidal peptides we call cysteine rich insecticidal peptides (CRIPS), and mixtures and/or compositions thereof with pore-forming insecticidal proteins (PFIPs). The present invention also describes mixtures and compositions of CRIPs with Bacillus thuringiensis (Bt), and the genes and/or proteins therefrom, in various formulations and combinations, of both genes and peptides, useful for the control of insects.Type: ApplicationFiled: May 1, 2020Publication date: August 13, 2020Applicant: Vestaron CorporationInventors: Robert M. KENNEDY, Lin BAO
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Publication number: 20200207818Abstract: New insecticidal proteins, nucleotides, peptides, their expression in plants, methods of producing the peptides, new processes, production techniques, new peptides, new formulations, new organisms, and a process which increases the insecticidal peptide production yield from yeast expression systems. The present invention is also related to novel cell culture methods and conditions that can be used to express heterologous polypeptides, along with new transgenic yeast strains.Type: ApplicationFiled: January 14, 2020Publication date: July 2, 2020Applicant: Vestaron CorporationInventors: Kyle Schneider, Catherine L. Foune, Lin Bao, Robert Venable, Robert M. Kennedy
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Publication number: 20200181212Abstract: Described are the artificially induced conversion of certain toxic peptides to create both different forms of those peptides and new and useful derivatives of the original peptides that are both useful by themselves and useful as new compounds and new stable intermediates that may be used to make other important compounds.Type: ApplicationFiled: December 13, 2019Publication date: June 11, 2020Applicant: Vestaron CorporationInventors: Robert M. Kennedy, Lin Bao, Alvar R. Carlson, Catherine L. Foune, Alexandra M. Haase, Bruce A. Steinbaugh
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Patent number: 10669319Abstract: New insecticidal proteins, nucleotides, peptides, their expression in plants, methods of producing the peptides, new processes, production techniques, new peptides, new formulations, and new organisms, a process which increases the insecticidal peptide production yield from yeast expression systems. The present invention is also related and discloses selected endotoxins we call cysteine rich insecticidal peptides (CRIPS) which are peptides derived from Bacillus thuringiensis (Bt) and their genes and endotoxins in combination with toxic peptides known as Inhibitor Cystine Knot (ICK) genes and peptides as well as with other types of insecticidal peptides such as trypsin modulating oostatic factor (TMOF) peptide sequences used in various formulations and combinations; of both genes and peptides, useful for the control of insects.Type: GrantFiled: December 23, 2016Date of Patent: June 2, 2020Assignee: Vestaron CorporationInventors: Robert M. Kennedy, William Tedford, Christopher Hendrickson, Robert Venable, Catherine Foune, John McIntyre, Alvar Carlson, Lin Bao
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Publication number: 20180362598Abstract: A peptide comprised of either a binary or a tertiary peptide, the peptide contains at least 4 amino acids and up to a maximum of 16 amino acids, comprised of 2 or 3 different regions, wherein the binary peptides have 2 different regions and the tertiary peptides have 3 different regions; wherein, the peptide can be cleaved by both an animal gut protease and an insect or nematode gut protease.Type: ApplicationFiled: October 6, 2017Publication date: December 20, 2018Applicant: VESTARON CORPORATIONInventors: ALVAR R. CARLSON, ALEXANDRA M. HAASE, ROBERT M. KENNEDY
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Publication number: 20180186846Abstract: New insecticidal proteins, nucleotides, peptides, their expression in plants, methods of producing the peptides, new processes, production techniques, new peptides, new formulations, and new organisms, a process which increases the insecticidal peptide production yield from yeast expression systems. The present invention is also related and discloses selected endotoxins we call cysteine rich insecticidal peptides (CRIPS) which are peptides derived from Bacillus thuringiensis (Bt) and their genes and endotoxins in combination with toxic peptides known as Inhibitor Cystine Knot (ICK) genes and peptides as well as with other types of insecticidal peptides such as trypsin modulating oostatic factor (TMOF) peptide sequences used in various formulations and combinations; of both genes and peptides, useful for the control of insects.Type: ApplicationFiled: December 23, 2016Publication date: July 5, 2018Applicant: Vestaron CorporationInventors: Robert M. Kennedy, William Tedford, Christopher Hendrickson, Robert Venable, Catherine Foune, John McIntyre, Alvar Carlson, Lin Bao
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Publication number: 20170174731Abstract: New insecticidal proteins, nucleotides, peptides, their expression in plants, methods of producing the peptides, new processes, production techniques, new peptides, new formulations, and new organisms, a process which increases the insecticidal peptide production yield from yeast expression systems. The present invention is also related and discloses selected endotoxins we call cysteine rich insecticidal peptides (CRIPS) which are peptides derived from Bacillus thuringiensis (Bt) and their genes and endotoxins in combination with toxic peptides known as Inhibitor Cystine Knot (ICK) genes and peptides as well as with other types of insecticidal peptides such as trypsin modulating oostatic factor (TMOF) peptide sequences used in various formulations and combinations; of both genes and peptides, useful for the control of insects.Type: ApplicationFiled: December 23, 2016Publication date: June 22, 2017Applicant: Vestaron CorporationInventors: Robert M. Kennedy, William Tedford, Christopher Hendrickson, Robert Venable, Catherine Foune, John McIntyre, Alvar Carlson, Lin Bao
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Publication number: 20170121377Abstract: Described are the artificially induced conversion of certain toxic peptides to create both different forms of those peptides and new and useful derivatives of the original peptides that are both useful by themselves and useful as new compounds and new stable intermediates that may be used to make other important compounds.Type: ApplicationFiled: April 3, 2015Publication date: May 4, 2017Applicant: Vestaron CorporationInventors: Robert M. Kennedy, Lin Bao, Alvar R. Carlson, Catherine L. Foune, Alexandra M. Haase, Bruce A. SteinBaugh
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Patent number: 9567381Abstract: New insecticidal proteins, nucleotides, peptides, their expression in plants, methods of producing the peptides, new processes, production techniques, new peptides, new formulations, and new organisms, a process which increases the insecticidal peptide production yield from yeast expression systems. The present invention is also related and discloses selected endotoxins we call cysteine rich insecticidal peptides (CRIPS) which are peptides derived from Bacillus thuringiensis (Bt) and their genes and endotoxins in combination with toxic peptides known as Inhibitor Cystine Knot (ICK) genes and peptides as well as with other types of insecticidal peptides such as trypsin modulating oostatic factor (TMOF) peptide sequences used in various formulations and combinations; of both genes and peptides, useful for the control of insects.Type: GrantFiled: March 8, 2013Date of Patent: February 14, 2017Assignee: Vestaron CorporationInventors: Robert M. Kennedy, William Tedford, Christopher Hendrickson, Robert Venable, Catherine Foune, John McIntyre, Alvar Carlson, Lin Bao