Abstract: This invention concerns a diagnostic system made of: a transformed microorganism capable of an increased reporter activity upon exposure to an environmental insult, said microorganism having a stress inducible promoter sequence being operatively linked to a reported encoding nucleic acid sequence encoding a reporter molecule resulting in a signal that can be assayed, and of a transformed microorganism having a constitutive and non stress inducible promoter sequence being operatively linked to a reporter encoding nucleic acid sequence encoding a reporter molecule resulting in a signal that can be assayed.
Type:
Grant
Filed:
January 27, 2000
Date of Patent:
October 29, 2002
Assignee:
Vlaamse Instelling Voor Technologish Onderzoek (VITO)
Inventors:
Daniel Van Der Lelie, Luc Agnes Louis Jean Bosco Regniers, Safiyh Taghavi, Philippe Gilbert Ghislain Corbisier, Luc Philippine Edouard Verschaeve