Patents Assigned to Vrije Univeriteit Brussel
  • Opioid receptor binding agents and uses thereof
    Patent number: 11352422
    Abstract: Agents that specifically bind to an opioid receptor in a conformationally specific way can be used to induce a conformational change in the receptor. Such agents have therapeutic applications and can be used in X-ray crystallography studies of the receptor. Such agents can also be used to improve drug discovery via compound screening and/or structure-based drug design.
    Type: Grant
    Filed: March 15, 2019
    Date of Patent: June 7, 2022
    Assignees: VIB VZW, Vrije Univeriteit Brussel, Board of Trustees Leland Stanford Jr University
    Inventors: Jan Steyaert, Toon Laeremans, Els Pardon, Brian Kobilka, Aashish Manglik