Abstract: Efficacious phenol-free mycobactericidal liquid compositions having low odor and irritation potential are disclosed. These compositions consist of a solvent containing a glycol, a 2 to 6 carbon atom aldehyde, specific anionic surfactants, and buffer salts to stabilize the pH in the 6 to 7.4 range. The ratio of glycol to aldehyde is comprised between 0.1 and 6.0. The lower this ratio, the greater the mycobactericidal activity. The new odorless compositions can kill Mycobacterium tuberculosis (EPA quantitative procedure) in 10 minutes or less at 20.degree. C.
Abstract: Very potent, stable, ordorless, and phenol-free virciudal solutions are active at high dilution when used for surface decontamination of animate and inanimate objects. The virucidal compositions described are efficacious in a matter of minutes against both the lipophilic and the more resistant hydrophilic viruses. The three active ingredients in these virucidal compositions are the glutaraldehyde monomer in equilibrium with its hydrates and polymers, hydrogen-bonded glycol molecules to eliminate aldehydes odor, and an anionic surfactant of the alkyl sulfate, alkyl sulfonate, alcohol sulfate or alkyl aryl sulfonate type. A preferred anionic surfactant would be the Sodium Dodecyl Sulfate (SDS), which exhibits strong cidal synergism against the Herpes Simplex Virus type 1 when mixed at a concentration as low as 0.0005% in diluted glutaraldehyde aqueous solutions (0.0025%). Improved virucidal killing at higher dilutions of the same formula were observed with the more resistant Coxsackie B viruses.
Abstract: This invention relates to a method for disinfecting or sterilizing medical, surgical, dental instruments or other objects in liquid phase with improved sporidical compositions. The method object of the invention is based upon the synergistic effects observed when combining nonionic and anionic surfactants with aqueous or alcoholic glutaraldehyde solutions. The method can be used also with ultrasonic irradiation over a wide frequency range (10 to 850 kHz). Two types of particularly effective synergistic sporicidal compositions are also described.
Abstract: This invention relates to a method for disinfecting or sterilizing medical, surgical, dental instruments or other objects in liquid phase with improved sporicidal compositions. The method object of the invention is based upon the synergistic effects observed when combining non-ionic and anionic surfactants with aqueous or alcoholic glutaraldehyde solutions. The method can be used also with ultrasonic irradiation over a wide frequency range (10 to 850 kHz). Two types of particularly effective synergistic sporicidal compositions are also described. Another modification is the use of the composition for disinfecting broiler eggs in breeder farms and commercial hatcheries.