Abstract: The present disclosure provides methods for quantifying target analytes in sample by providing framework for expanded multiplexing through asynchronous fingerprinting.

Abstract: A simple immunosensor for rapid and high sensitivity measurements of protein biomarkers, such as SARS-CoV-2 nucleocapsid protein, in serum. The assay is based on a unique sensing scheme utilizing dually labeled magnetic nanobeads for immunomagnetic enrichment and signal amplification. This immunosensor can be integrated onto a microfluidic chip, which offers the advantages of minimal sample and reagent consumption, simplified sample handling, and enhanced detection sensitivity. An ultrafast magneto-immunosensor, which employs AC electrothermally driven flow (ACEF) for accelerated mass transport and enhanced immunocomplex formation, is developed for high sensitivity protein measurement in whole blood samples.

Abstract: Ultrafast flash Joule heating synthesis methods and systems, and more particularly, ultrafast synthesis methods to recover metal from ores, fly ash, and bauxite residue (red mud).

Abstract: Ultrafast flash Joule heating synthesis methods and systems, and more particularly, ultrafast synthesis methods to recover precious metals recovery and other metals from electronic waste (e-waste).

Abstract: Laser-induced graphene (LIG) and laser-induced graphene scrolls (LIGS) materials and, more particularly to LIGS, methods of making LIGS (such as from polyimide (PI)), laser-induced removal of LIG and LIGS, and 3D printing of LIG and LIGS using a laminated object manufacturing (LOM) process.

Abstract: In one aspect, the present disclosure describes ultrasmall gas vesicle compositions comprising modified gas vesicle shell proteins. Also disclosed herein are polynucleotide sequences which encode such compositions. Methods of treatment comprising administering such gas vesicle compositions are also provided.

Abstract: A high-resolution microendoscope system includes a light source, a fiber optic bundle configured to transmit light from the light source to a sample, a disc configured to receive light returned from the sample, the disc having spaced apart segments, the spaced-apart segments being at least one of openings and transparent portions, a first camera configured to capture a first image based at least in part on light passing through the disc, and a second camera configured to capture a second image based at least in part on light reflected from the disc.

Abstract: A method for processing formulae includes encoding a formula by: training, with a server, a model by using a machine learning algorithm with a data set that includes a plurality of formulae; transforming, with a processor, a first formula into a tree format using the trained model; converting, with the processor, the tree format of the first formula into a plurality of lists; and encoding, with the processor, the plurality of lists into a fixed dimension vector by leveraging a stacked attention module; and generating one or more formula candidates by: obtaining, with the processor, input information; and generating, with the processor, one or more second formula candidates based on input information by using the stacked attention module with a tree beam search algorithm.

Abstract: Provided herein are non-extensible oligonucleotides for suppressing enzymatic extension through rationally designed secondary structures at the 3? end. Embodiments of the invention include procedures for integration with real-time polymerase chain reaction, blocker displacement amplification in quantitative PCR, next generation sequencing (NGS), and long-read sequencing.

Abstract: A process for making a layered multi-material structural element having controlled mechanical failure characteristics. The process includes the steps of: supplying a cementitious layer and forming a polymer layer on the cementitious layer by additive manufacture such that the polymer layer has a first thickness and the cementitious layer has a second thickness, wherein the polymer layer comprises a polymer and the cementitious layer comprises a cementitious material; and allowing the polymer from the polymer layer to suffuse into the cementitious layer for a period of time to obtain a suffused zone in the cementitious layer such that the suffused zone has a third thickness that is less than half the second thickness.

Abstract: A process for making a layered multi-material structural element having controlled mechanical failure characteristics. The process includes the steps of: supplying a cementitious layer and forming a polymer layer on the cementitious layer by additive manufacture such that the polymer layer has a first thickness and the cementitious layer has a second thickness, wherein the polymer layer comprises a polymer and the cementitious layer comprises a cementitious material; and allowing the polymer from the polymer layer to suffuse into the cementitious layer for a period of time to obtain a suffused zone in the cementitious layer such that the suffused zone has a third thickness that is less than half the second thickness.

Abstract: A process for making a layered multi-material structural element having controlled mechanical failure characteristics. The process includes the steps of: supplying a cementitious layer and forming a polymer layer on the cementitious layer by additive manufacture such that the polymer layer has a first thickness and the cementitious layer has a second thickness, wherein the polymer layer comprises a polymer and the cementitious layer comprises a cementitious material; and allowing the polymer from the polymer layer to suffuse into the cementitious layer for a period of time to obtain a suffused zone in the cementitious layer such that the suffused zone has a third thickness that is less than half the second thickness.

Abstract: A process for making a layered multi-material structural element having controlled mechanical failure characteristics. The process includes the steps of: supplying a cementitious layer and forming a polymer layer on the cementitious layer by additive manufacture such that the polymer layer has a first thickness and the cementitious layer has a second thickness, wherein the polymer layer comprises a polymer and the cementitious layer comprises a cementitious material; and allowing the polymer from the polymer layer to suffuse into the cementitious layer for a period of time to obtain a suffused zone in the cementitious layer such that the suffused zone has a third thickness that is less than half the second thickness.

Abstract: Embodiments of the present disclosure pertain to electrodes for energy storage devices. The electrodes include a substrate from which extends bundles of carbon nanotubes. A metal, such as lithium, infiltrates the bundles, between the carbon nanotubes, to coat the surfaces of the carbon nanotubes. The bundled, metal-coated carbon nanotubes are covered with a layer of solid-electrolyte interphase that can be formed before the metal is inserted into the bundles by pretreating the bundles with an electrolyte bearing ions of the metal.

Abstract: In one aspect, the present disclosure provides methods of preparing a secondary amine. In some embodiments, the secondary amine comprises two different groups or two identical groups. Also provided herein are compositions for use in the preparation of the secondary amine.

Abstract: Energy-storage devices in which the energy storage device has an electrode that includes graphitic carbon, carbon nanotubes, and a metallic-lithium layer between the carbon nanotubes and the energy-storage device further has an electrolyte that is in contact with the metallic lithium layer. The methods of manufacturing the energy-storage devices include that the energy storage device is made by providing electrodes that have a layer of carbon nanotubes adjacent additional carbon, applying a layer of lithium between the carbon nanotubes in the layer of carbon nanotubes of at least one of the electrodes, and providing an electrolyte between the electrodes.

Abstract: The present disclosure is directed to composition and methods for use in drug screening methods. The identification of microbial strains producing antibiotics effective against multi-drug resistant bacterial pathogens using microfluidics and co-encapsulation of predator and prey strains permits rapid and multiplexed assessment of new antibiotics for emerging bacterial pathogens including those resistant to multiple existing antibiotics.

Abstract: A method of forming an electrode for capacitive deionization includes depositing an slurry onto a substrate, wherein the slurry comprises a porous material, a first crosslinkable hydrophilic polymer, and a crosslinker for the first crosslinkable hydrophilic polymer; annealing the slurry deposited on the substrate to create a crosslinked porous layer on the substrate; depositing an solution comprising an ion-exchange material, a second crosslinkable hydrophilic polymer, and a crosslinker for the second crosslinkable hydrophilic polymer onto the crosslinked porous layer; and optionally annealing and/or drying the solution on the crosslinked porous layer.

Abstract: The present disclosure relates to implantable constructs (encapsulated cells) designed to deliver antigenic therapeutic reagents, such as IL-2.

Abstract: A process for making a layered multi-material structural element having controlled mechanical failure characteristics. The process includes the steps of: supplying a cementitious layer and forming a polymer layer on the cementitious layer by additive manufacture such that the polymer layer has a first thickness and the cementitious layer has a second thickness, wherein the polymer layer comprises a polymer and the cementitious layer comprises a cementitious material; and allowing the polymer from the polymer layer to suffuse into the cementitious layer for a period of time to obtain a suffused zone in the cementitious layer such that the suffused zone has a third thickness that is less than half the second thickness.