Patents Assigned to Yissum Research Development Company of the Hebrew University
  • Publication number: 20190330138
    Abstract: The present invention provides compounds comprising fused tricyclic backbone structure and processes for their preparation. The invention further provides compounds and compositions useful in the treatment of pain and any type of disorder or symptom associated therewith.
    Type: Application
    Filed: June 17, 2019
    Publication date: October 31, 2019
    Applicant: Yissum Research Development Company of the Hebrew University of Jerusalem Ltd.
    Inventors: Dmitry TSVELIKHOVSKY, Avi PRIEL
  • Patent number: 10455857
    Abstract: The present invention provides a liquid coloring composition comprising of a coffee solution or coffee extract and an ink vehicle. The coloring composition is suitable for use as an ink in a non-impact printing device, including an ink jet type printer. The composition is composed of edible components. The invention further provides a process for applying a design to a food substrate, comprising of providing a non-impact printing device, wherein the ink cartridge or external container contains the coloring composition of the invention.
    Type: Grant
    Filed: October 8, 2014
    Date of Patent: October 29, 2019
    Assignees: Ripples Ltd., Yissum Research Development Company of the Hebrew University of Jerusalem
    Inventors: Eyal Eliav, Danny Lavie, Shlomo Magdassi
  • Publication number: 20190314326
    Abstract: Provided are cannabinoid-loaded formulations, as well as processes for their preparation.
    Type: Application
    Filed: September 28, 2017
    Publication date: October 17, 2019
    Applicant: Yissum Research Development Company of the Hebrew University of Jerusalem Ltd.
    Inventors: Nissim GARTI, Sharon GARTI LEVI, Rotem EDRI
  • Publication number: 20190314432
    Abstract: Provided are methods for extraction of various agents, e.g. active agent, from a plant source, specifically with the use of extraction formulations which are based on micellar liquid systems.
    Type: Application
    Filed: September 28, 2017
    Publication date: October 17, 2019
    Applicant: Yissum Research Development Company of the Hebrew University of Jerusalem Ltd.
    Inventors: Nissim GARTI, Sharon GARTI LEVI, Rotem EDRI
  • Publication number: 20190315669
    Abstract: The invention provides processes for the preparation of HU-910, which are scalable to industrial purposes, using safer reagents and having high yield and pure product and a crystalline structure of HU-910, which is a unique product thereof.
    Type: Application
    Filed: November 13, 2017
    Publication date: October 17, 2019
    Applicant: Yissum Research Development Company of The Hebrew University of Jerusalem Ltd.
    Inventors: Jean-Michel ADAM, Pascal DOTT, Marcus HOHLER, Tanja BURGER, Orazio TAGLIENTE, Ernst MISCHLER
  • Patent number: 10441553
    Abstract: The present invention relates to fluorine substituted CBD compounds, compositions thereof and uses thereof for the preparation of medicaments.
    Type: Grant
    Filed: August 1, 2017
    Date of Patent: October 15, 2019
    Assignees: UNIVERSIDADE DE SAO PAULO—USP, UNIVERSIDADE FEDERAL DO RIO GRANDE DO SUL—UFRGS, YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JESUSALEM LTD
    Inventors: Raphael Mechoulam, Antonio Waldo Zuardi, Flavio Pereira Kapczinski, Jaime Eduardo Cecilio Hallak, Francisco Silveira Guimaraes, Jose Alexandre de Souza Crippa, Aviva Breuer
  • Patent number: 10441568
    Abstract: Cyclic nitroxide compounds including, but not limited to, compounds having the general formula I: wherein the dashed line and R1-R8 are as defined herein, are disclosed herein for use in treating diseases and disorders of the respiratory tract and/or respiratory tract remodeling.
    Type: Grant
    Filed: March 24, 2016
    Date of Patent: October 15, 2019
    Assignees: Yissum Research Development Company of the Hebrew University of Jerusalem Ltd., Hadasit Medical Research Services and Development Ltd.
    Inventors: Sara Goldstein, Amram Samuni, Neville Berkman
  • Patent number: 10442944
    Abstract: Provided is a novel photoinitiator in the form of a hybrid nanoparticle constructed of a semiconductor and metallic regions, and uses thereof.
    Type: Grant
    Filed: June 29, 2016
    Date of Patent: October 15, 2019
    Assignee: Yissum Research Development Company of the Hebrew University of Jerusalem Ltd.
    Inventors: Uri Banin, Hermona Soreq, Shlomo Magdassi, Nir Waiskopf, Yuval Ben-Shahar, Amol Ashok Pawar, Shira Halivni
  • Patent number: 10428328
    Abstract: Oligonucleotides capable of binding to and modulating the splicing of the pre-mRNA of the CFTR gene, compositions including the oligonucleotides, kits including the compositions, and uses thereof. Compositions of oligonucleotides useful in methods for suppressing exon 10 skipping optionally in combination with additional CFTR therapeutics.
    Type: Grant
    Filed: March 24, 2015
    Date of Patent: October 1, 2019
    Assignee: YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD.
    Inventors: Batsheva Kerem, Michal Tur Sinai, Loren Price, Stephen Donald Wilton, Sue Fletcher
  • Patent number: 10413515
    Abstract: Provided are hydrocolloid core-shell capsules including a liquid core including a non-crosslinked alginate solution and a solid or semi-solid shell including a hydrocolloid other than alginate crosslinked with metal ions, which do not crosslink alginate. Further provided is a method for the preparation of the liquid-core capsules including non-crosslinked alginate. The subject matter further provides the use of the capsules, inter alia, in the water treatment technology.
    Type: Grant
    Filed: December 29, 2015
    Date of Patent: September 17, 2019
    Assignee: Yissum Research Development Company of the Hebrew University of Jerusalem Ltd.
    Inventors: Amos Nussinovitch, Orit Dagan
  • Patent number: 10412901
    Abstract: Provided is a system (1) and method for identifying one or more plants in a population of two or more plants (4). The method includes monitoring one or more parameters of a plant (4) of the population and generating one or more time signals indicative of values of the one or more parameters. The signals are processed to calculate one or both of a transpiration rate of each plant and a rate of change of a transpiration rate over each of one or more time intervals. The plants are then ranked using an algorithm involving the calculated transpiration rates, and plants having a ranking above a predetermined ranking are identified. Further provided is a system for carrying out the method of the invention.
    Type: Grant
    Filed: November 1, 2009
    Date of Patent: September 17, 2019
    Assignee: Yissum Research Development Company of the Hebrew University of Jerusalem Ltd.
    Inventors: Menachem Moshelion, Rony Wallach
  • Patent number: 10392338
    Abstract: The present invention provides compounds comprising fused tricyclic backbone structure and processes for their preparation. The invention further provides compounds and compositions useful in the treatment of pain and any type of disorder or symptom associated therewith.
    Type: Grant
    Filed: January 28, 2016
    Date of Patent: August 27, 2019
    Assignee: YISSUM RESEARCH DEVELOPMENT COMPANY, OF THE HEBREW UNIVERSITY OF JERUSALEM LTD.
    Inventors: Dmitry Tsvelikhovsky, Avi Priel
  • Patent number: 10387534
    Abstract: A computerized method comprising operating one or more hardware processor for receiving a first matrix and a second matrix. The hardware processor(s) are operated for determining a basis transformation, wherein the basis transformation is invertible to an inverted basis transformation. The hardware processor(s) are operated for computing an alternative basis first matrix by multiplying the first matrix by the basis transformation. The hardware processor(s) are operated for computing an alternative basis second matrix by multiplying the second matrix by the basis transformation. The hardware processor(s) are operated for performing a matrix multiplication of the alternative basis first matrix and the alternative basis second matrix, thereby producing an alternative basis multiplied matrix. The hardware processor(s) are operated for computing a multiplied matrix by multiplying the alternative basis multiplied matrix by the inverted basis transformation.
    Type: Grant
    Filed: November 28, 2017
    Date of Patent: August 20, 2019
    Assignee: YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD.
    Inventors: Oded Schwartz, Elaye Karstadt
  • Patent number: 10376511
    Abstract: The present invention provides pyrazole pyrimidine derivatives which inhibit Casein kinase I (CKI) and/or Interleukin-1 receptor-associated kinase 1 (IRAKI) and methods of their manufacture, compositions comprising them and uses thereof in methods of treating malignant disease and disorders and methods for treating inflammatory diseases and disorders.
    Type: Grant
    Filed: August 4, 2016
    Date of Patent: August 13, 2019
    Assignee: Yissum Research Development Company of the Hebrew University of Jerusalem LTD.
    Inventors: Yinon Ben Neriah, Guy Brachya, Ido Burstain, Waleed Minzel, Irit Snir-Alkalay, Joseph Vacca, Dansu Li
  • Publication number: 20190231833
    Abstract: Provided are methods for selective extraction of cannabinoids, for example cannabidiol (CBD), from a plant source, by using tailored extraction media.
    Type: Application
    Filed: September 28, 2017
    Publication date: August 1, 2019
    Applicant: Yissum Research Development Company of the Hebrew University of Jerusalem Ltd.
    Inventors: Nissim GARTI, Sharon GARTI LEVI, Rotem EDRI
  • Publication number: 20190218412
    Abstract: Provided is a method for modifying at least one property of a solid film or coat including or consisting nanocrystalline cellulose (NCC).
    Type: Application
    Filed: May 16, 2017
    Publication date: July 18, 2019
    Applicants: Yissum Research Development Company of the Hebrew University of Jerusalem Ltd, MELODEA LTD.
    Inventors: Tal BEN SHALOM, Oded SHOSEYOV, Shaul LAPIDOT, Clarite AZERRAF, Yuval NEVO
  • Publication number: 20190209466
    Abstract: An ophthalmic composition useful for the treatment of bacterial eye infections is provided. The ophthalmic composition includes the suspension of particles of active anti-bacterial agent in a gelled matrix.
    Type: Application
    Filed: September 3, 2017
    Publication date: July 11, 2019
    Applicants: DEXCEL PHARMA TECHNOLOGIES LTD., YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD.
    Inventors: Simon BENITA, Taher NASSAR
  • Publication number: 20190201349
    Abstract: Provided are antifouling particles and uses thereof in methods of anti-biofouling.
    Type: Application
    Filed: October 26, 2016
    Publication date: July 4, 2019
    Applicant: Yissum Research Development Company of the Hebrew University of Jerusalem Ltd.
    Inventors: Meital RECHES, Sivan NIR
  • Publication number: 20190201478
    Abstract: Provided is a nanoparticle associated with a plurality of oleylcysteineamide (OCA) molecules for a variety of therapeutic applications. At least a portion of the OCA molecules may be associated with at least one therapeutic agent or at least one non-active agent. Also provided is a drug delivery agent including at least one nanoparticle associated with a plurality of OCA molecules. At least a portion of the OCA molecules is associated with at least one therapeutic agent or at least one or non-active agent. Also provided is a method of delivering a drug to a subject. The method includes administering the drug delivery agent (associated with the drug) to the subject.
    Type: Application
    Filed: March 7, 2019
    Publication date: July 4, 2019
    Applicant: Yissum Research Development Company of the Hebrew University of Jerusalem Ltd.
    Inventors: Simon BENITA, Taher NASSER, Nour KARRA, Amit BADIHI
  • Patent number: 10331913
    Abstract: A method for searchable symmetric encryption. The method includes: accessing a computerized database that comprises keyword lists, each of the keyword lists comprising memory addresses of electronic documents that all contain a respective keyword; binning the memory addresses by performing balanced allocation of the memory addresses into ordered bins, such that at least some of the ordered bins each contains memory addresses of electronic documents that contain different keywords; encrypting each of the memory addresses with an encryption key that is derived from the keyword of the respective memory address; and storing the ordered bins at consecutive locations in a non-transient computer-readable memory, wherein the consecutive locations preserve the order of the ordered bins.
    Type: Grant
    Filed: January 19, 2017
    Date of Patent: June 25, 2019
    Assignees: Yissum Research Development Company of the Hebrew University of Jerusalem Ltd., Yeda Research and Development Co. Ltd.
    Inventors: Gil Segev, Ido Shahaf, Gilad Asharov, Moni Naor