Patents Assigned to Yissum Research Development Company of the Hebrew University
  • Hybrid nanopores and uses thereof for detection of analytes
    Patent number: 10179933
    Abstract: The invention relates to a hybrid structure including perforated solid substrate having at least one nanopore perforating therethrough, and devices and uses thereof.
    Type: Grant
    Filed: February 6, 2014
    Date of Patent: January 15, 2019
    Assignee: Yissum Research Development Company of the Hebrew University of Jerusalem Ltd.
    Inventors: Danny Porath, Oded Shoseyov, Yuval Nevo, Ke Liu, Dvir Marom Rotem
  • DELIVERY SYSTEMS FOR PROPOFOL
    Publication number: 20190008770
    Abstract: Provided is a novel dilutable delivery systems and propofol microemulsions suitable for intravenous delivery of propofol.
    Type: Application
    Filed: June 29, 2016
    Publication date: January 10, 2019
    Applicant: Yissum Research Development Company of the Hebrew University of Jerusalem Ltd.
    Inventors: Nissim GARTI, Sharon GARTI LEVI, Abraham ASERIN, My PERLSTEIN
  • Downregulating miR-132 for the treatment of lipid related disorders
    Patent number: 10174320
    Abstract: A method of treating a lipid-related disorder in a subject in need thereof is disclosed. The method comprises administering to the subject a therapeutically effective amount of a polynucleotide agent which is substantially complementary to a nucleotide sequence of human miR-132, thereby treating the lipid related disorder in the subject.
    Type: Grant
    Filed: September 21, 2015
    Date of Patent: January 8, 2019
    Assignee: Yissum Research Development Company of the Hebrew University of Jerusalem Ltd.
    Inventors: Hermona Soreq, Geula Hanin, David S. Greenberg
  • METHOD AND SYSTEM FOR ENHANCING A SPEECH SIGNAL OF A HUMAN SPEAKER IN A VIDEO USING VISUAL INFORMATION
    Publication number: 20190005976
    Abstract: A method and system for enhancing a speech signal is provided herein. The method may include the following steps: obtaining an original video, wherein the original video includes a sequence of original input images showing a face of at least one human speaker, and an original soundtrack synchronized with said sequence of images; and processing, using a computer processor, the original video, to yield an enhanced speech signal of said at least one human speaker, by detecting sounds that are acoustically unrelated to the speech of the at least one human speaker, based on visual data derived from the sequence of original input images.
    Type: Application
    Filed: July 3, 2018
    Publication date: January 3, 2019
    Applicant: Yissum Research Development Company of the Hebrew University of Jerusalem Ltd.
    Inventors: Shmuel PELEG, Asaph Shamir, Tavi Halperin, Aviv Gabbay, Ariel Ephrat, Ariel Ephrat
  • Treatment of hepatic encephalopathy and liver cirrhosis
    Patent number: 10166202
    Abstract: The compounds D9-tetrahydrocannabinol (THC), cannabidiol (CBD) and capsaicin are useful for prevention, treatment, or both, of hepatic encephalopathy. The compounds capsaicin, 2-arachidonoylglycerol (2-AG), HU-308 and cannabidiol are useful for prevention, treatment, or both, of liver cirrhosis.
    Type: Grant
    Filed: June 16, 2011
    Date of Patent: January 1, 2019
    Assignees: Yissum Research Development Company of the Hebrew University of Jerusalem, Hadasit Medical Research Services & Development Ltd., Aristotle University of Thessaloniki
    Inventors: Elliot Berry, Yosefa Avraham, Raphael Mechoulam, Yaron Ilan, Yossi Dagon, Iddo Magen, Nicholas Grigoriadis, Theofilos Poutachidis
  • METHODS OF GENERATING TISSUE USING DEVITALIZED, ACELLULAR SCAFFOLD MATRICES DERIVED FROM MICRO-ORGANS
    Publication number: 20180371407
    Abstract: A composition of matter is provided comprising a devitalized, acellular tissue-derived scaffold seeded with differentiated cells, particularly pancreatic islet cells, wherein the cells can maintain cell-specific function or structure in culture on the scaffold. Methods of generating same and uses thereof are also provided.
    Type: Application
    Filed: September 7, 2018
    Publication date: December 27, 2018
    Applicant: YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD.
    Inventor: Eduardo N. MITRANI
  • Method and Apparatus for CO2 Sequestration
    Publication number: 20180371506
    Abstract: Processes, methods, and apparatus for carbon sequestration utilizing catalysis schemes configured to provide high concentrations of hydrated CO2 in proximity with a sequestration agent are provided. Reactants are combined with catalyst such that at least two regions of controlled catalytic activity form encompassing at least the interface between a sequestration agent and an aqueous solution containing dissolved CO2. Suitable reactants include various sequestration agents, catalyst, and carbon dioxide dissolved in an aqueous solution (seawater, for example). Possible products include bicarbonate and metal cations.
    Type: Application
    Filed: June 1, 2018
    Publication date: December 27, 2018
    Applicants: California Institute of Technology, University of Southern California, Yissum Research Development Company of the Hebrew University of Jerusalem Ltd.
    Inventors: Adam Vinay Subhas, William Max Berelson, Nick Everett Rollins, Jess Firey Adkins, Jonathan Erez
  • Colloidal semiconductor metal chalcogenide nanostructures
    Patent number: 10160648
    Abstract: This invention generally relates to metal chalcogenide nanostructures, methods for their preparation and methods of use. A method is disclosed that transforms zinc chalcogenide nanowires into nanorods or quadrilateral nanostructures in an anneal step. Particular embodiments comprise ZnO nanostructures.
    Type: Grant
    Filed: July 1, 2014
    Date of Patent: December 25, 2018
    Assignees: YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD., QLIGHT NANOTECH LTD.
    Inventors: Uri Banin, Guohua Jia
  • SESAME CULTIVARS SUITABLE FOR MECHANICAL HARVEST WITH ENHANCED YIELD AND QUALITY
    Publication number: 20180359981
    Abstract: Provided are sesame plants having a mutation conferring closed capsules at maturity and means and methods for producing same. The plants of the present subject matter produce high yield of sesame seeds, the seeds having improved content of at least one of zinc, iron and calcium.
    Type: Application
    Filed: December 15, 2016
    Publication date: December 20, 2018
    Applicant: Yissum Research Development Company of the Hebrew University of Jerusalem Ltd.
    Inventors: Zvi PELEG, Naama TEBOUL, Yaron GADRI
  • Pomegranate oil for preventing and treating neurodegenerative diseases
    Patent number: 10154961
    Abstract: The present invention relates to the use of pomegranate oil and fractions thereof for preventing and treating neurodegenerative diseases. Particularly, the present invention relates to emulsions of the pomegranate oil or fractions thereof for the prevention and treatment of brain diseases, including Creutzfeldt-Jacob disease (CJD) and multiple sclerosis (MS).
    Type: Grant
    Filed: October 24, 2014
    Date of Patent: December 18, 2018
    Assignees: Hadasit Medical Research Services and Development Ltd., Yissum Research Development Company of the Hebrew University of Jerusalem Ltd.
    Inventors: Ruth Gabizon, Haim Ovadia, Oded Abramsky, Shlomo Magdassi, Liraz Larush
  • Antagonists of neurokinin B in fish reproduction
    Patent number: 10155790
    Abstract: Provided are Peptide-based neurokinin antagonists of fish reproduction. Compositions including antagonists of fish neurokinin and methods of inhibiting or delaying puberty, fish maturation or reproduction processes using these compounds are also provided.
    Type: Grant
    Filed: July 16, 2015
    Date of Patent: December 18, 2018
    Assignee: Yissum Research Development Company of the Hebrew University of Jerusalem Ltd.
    Inventors: Berta Levavi-Sivan, Chaim Gilon
  • HYBRID NANOPARTICLES AS PHOTOINITIATORS
    Publication number: 20180355200
    Abstract: Provided is a novel photoinitiator in the form of a hybrid nanoparticle constructed of a semiconductor and metallic regions, and uses thereof.
    Type: Application
    Filed: June 29, 2016
    Publication date: December 13, 2018
    Applicant: Yissum Research Development Company of the Hebrew University of Jerusalem Ltd.
    Inventors: Uri BANIN, Hermona SOREQ, Shlomo MAGDASSI, Nir WAISKOPF, Yuval BEN-SHAHAR, Amol ASHOK PAWAR, Shira HALIVNI
  • Reverse hexagonal mesophases (H) and uses thereof
    Patent number: 10149824
    Abstract: Reverse hexagonal mesophase (HII) liquid crystals provide multi-component hexagonal systems for use in solubilizing and/or protecting from degradation one or more bio-macromolecule and/or active material, and relates to therapeutic and non-therapeutic applications, such as an oral delivery system, where the mesophase is adapted for oral administration. The present invention provides the formation of mesophase systems of ternary glycerol monooleate (GMO)/water combinations which comprise at least one triglyceride or an equivalent thereof. At least one biomacromolecule or drug is incorporated in the mesophase of a pharmaceutical composition or oral delivery system.
    Type: Grant
    Filed: June 24, 2010
    Date of Patent: December 11, 2018
    Assignee: YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD.
    Inventors: Nissim Garti, Abraham Aserin, Dima Libster, Idit Amar-Yuli, Tehila Mishraki, Liron Bitan-Chervkovsky
  • Patterns of fluorescent seeded nanorods
    Patent number: 10151049
    Abstract: Provided are printed patterns and objects including, for example, a film or 3D object, which may include one or more nanorods. According to the subject matter provided, the nanorods may reduce or diminish inter-particle interaction in the pattern or object.
    Type: Grant
    Filed: July 14, 2015
    Date of Patent: December 11, 2018
    Assignee: Yissum Research Development Company of the Hebrew University of Jerusalem Ltd.
    Inventors: Uri Banin, Shlomo Magdassi, Shai Shemesh, Shira Halivni, Yelena Vinetsky
  • POLARIZED LIGHT SOURCE DEVICE
    Publication number: 20180348563
    Abstract: A polarized light source configured for use in display device and backlight unit is described. The polarized light source comprising: at least one optically active structure comprising a plurality of nanorods configured to emit light of one or more wavelengths in response to exciting pumping field, said plurality of nanorods comprising nanorods aligned with a predetermined alignment axis so as to produce a desired polarization direction of the emitted light; and a light directing assembly comprising one or more optical elements in optical path of light emitted from the light emitting structure, said light directing assembly being configured to enhance output of the emitted light from the emitting structure while substantially maintaining the polarization of the emitted light passing therethrough. Preferably, layers associated with the polarized light source are aligned with parallel principal axes.
    Type: Application
    Filed: June 25, 2018
    Publication date: December 6, 2018
    Applicants: Yissum Research Development Company of the Hebrew University of Jerusalem Ltd., Qlight Nanotech Ltd.
    Inventors: Uri BANIN, Ehud SHAVIV, Hagai ARBELL
  • PARTICULATE PHOTOINITIATORS AND USES THEREOF
    Publication number: 20180348631
    Abstract: Provided is a novel class of solid water-dispersible powders, including a plurality of water-insoluble photoinitiators in nanoparticle forms for use in water-based ink formulations.
    Type: Application
    Filed: November 23, 2016
    Publication date: December 6, 2018
    Applicant: Yissum Research Development Company of the Hebrew University of Jerusalem Ltd.
    Inventors: Shlomo MAGDASSI, Liraz LARUSH, Ido COOPERSTEIN, Amol Ashok PAWAR
  • ANTICONVULSANT CARBAMATE DERIVATIVES
    Publication number: 20180339963
    Abstract: The invention contemplates novel materials as anticonvulsant agents.
    Type: Application
    Filed: May 22, 2018
    Publication date: November 29, 2018
    Applicant: Yissum Research Development Company of the Hebrew University of Jerusalem Ltd.
    Inventors: Meir BIALER, David BIBI, Hafiz MAWASI
  • Crystalline coating and release of bioactive agents
    Patent number: 10137225
    Abstract: Articles-of-manufacturing comprising an object having a surface and at least a first layer of a first therapeutically active agent being deposited onto at least a continuous portion of the surface, wherein at least 50 weight percents of the first layer is the first therapeutically active agent in a crystalline form are disclosed. Methods utilizing such articles-of-manufacturing for treating medical conditions are also disclosed. Processes of preparing the articles-of-manufacturing by contacting a surface of the object with a solution containing the therapeutically active agent, without cooling the surface to a temperature below a temperature of the solution, are also disclosed.
    Type: Grant
    Filed: November 27, 2016
    Date of Patent: November 27, 2018
    Assignee: Yissum Research Development Company of the Hebrew University of Jerusalem Ltd.
    Inventors: Abraham Jacob Domb, Shady Farah
  • ATTENUATED OR INACTIVATED PATHOGENIC ESCHERICHIA COLI FOR TREATING UROGENITAL CANCER
    Publication number: 20180333439
    Abstract: The present invention provides attenuated or inactivated pathogenic bacteria having anti-cancer properties, compositions comprising the bacteria, and use thereof for treating cancers of the urogenital system.
    Type: Application
    Filed: November 10, 2015
    Publication date: November 22, 2018
    Applicants: YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD., HADASIT MEDICAL RESEARCH SERVICES AND DEVELOPMENT LTD.
    Inventors: Ofer MANDELBOIM, Gilad Benjamin BACHRACH, Chamutal GUR, Vladimir YUTKIN
  • NOVEL CANNABINOID FORMULATIONS
    Publication number: 20180325861
    Abstract: Provided are formulations and methods for improving oral bioavailability of cannabinoid compositions.
    Type: Application
    Filed: October 26, 2016
    Publication date: November 15, 2018
    Applicant: Yissum Research Development Company of the Hebrew University of Jerusalem Ltd.
    Inventors: Abraham J. DOMB, Amnon HOFFMAN, Dvora IZGELOV