Patents Assigned to Zeltiq Aesthetics, Inc.
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Patent number: 9132031Abstract: A cooling device for removing heat from subcutaneous lipid-rich cells of a subject having skin is provided. The cooling device includes a plurality of cooling elements movable relative to each other to conform to the contour's of the subject's skin. The cooling elements have a plurality of controllable thermoelectric coolers. The cooling elements can be controlled to provide a time-varying cooling profile in a predetermined sequence, can be controlled to provide a spatial cooling profile in a selected pattern, or can be adjusted to maintain constant process parameters, or can be controlled to provide a combination thereof.Type: GrantFiled: September 26, 2006Date of Patent: September 15, 2015Assignee: Zeltiq Aesthetics, Inc.Inventors: Mitchell Levinson, Jesse Nicasio Rosen, William Pennybacker
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Publication number: 20140316393Abstract: Systems and methods that enable delivery of radiofrequency energy and cryotherapy applications to adipose tissue for reduction and contouring of body fat are described herein. Aspects of the disclosure are directed to methods for reducing surface irregularities in a surface of a subject's skin resulting from an uneven distribution of adipose tissue in the subcutaneous layer. The method can include delivering capacitively coupled or conductively coupled radiofrequency energy to a target region of the subject at a frequency which selectively heats fibrous septae in a subcutaneous layer of the target region to a maximum temperature less than a fibrous septae denaturation temperature. Furthermore, the method can include removing heat such that lipid-rich lobules in the subcutaneous layer are affected while non-lipid-rich cells and lipid-rich regions adjacent to the fibrous septae are not substantially affected.Type: ApplicationFiled: February 20, 2014Publication date: October 23, 2014Applicant: Zeltiq Aesthetics, Inc.Inventor: Mitchell E. Levinson
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Publication number: 20140277302Abstract: A treatment system for cooling subcutaneous lipid-rich cells in a human subject includes an applicator and a control unit. The treatment system has a cooling mode for cooling tissue and a heating mode for warming tissue. The control unit includes a circulation circuit in fluid communication with the applicator, a chiller apparatus configured to chill fluid from the applicator circulation circuit, and a heater apparatus to warmed fluid from the applicator circulation circuit. The control unit mixes the chilled fluid and/or the warmed with fluid in the applicator circulation circuit control the temperature of the fluid circulated in the applicator.Type: ApplicationFiled: March 14, 2013Publication date: September 18, 2014Applicant: ZELTIQ AESTHETICS, INC.Inventors: Bryan J. Weber, Joseph Coakley, Mark William Baker, Thomas Burnell Reeve, III
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Publication number: 20140257443Abstract: Devices, systems and methods for removing heat from subcutaneously disposed lipid-rich cells are disclosed. In selected embodiments, suction and/or heat removal sources are coupled to an applicator. The applicator includes a flexible portion and a rigid portion. The rigid portion includes a thermally conductive plate and a frame coupling the thermally conductive plate and the flexible portion. An interior cavity of the applicator is in fluid communication with the suction source, and the frame maintains contiguous engagement between the heat removal source and the thermally conductive plate.Type: ApplicationFiled: March 12, 2014Publication date: September 11, 2014Applicant: ZELTIQ AESTHETICS, INC.Inventors: Mark William Baker, Joseph Coakley, Paul William Martens, Albert L. Ollerdessen, William Patrick Pennybacker, Jesse N. Rosen, Peter Yee, John W. Allison, Bryan J. Weber
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Patent number: 8702774Abstract: Devices, systems and methods for removing heat from subcutaneously disposed lipid-rich cells are disclosed. In selected embodiments, suction and/or heat removal sources are coupled to an applicator. The applicator includes a flexible portion and a rigid portion. The rigid portion includes a thermally conductive plate and a frame coupling the thermally conductive plate and the flexible portion. An interior cavity of the applicator is in fluid communication with the suction source, and the frame maintains contiguous engagement between the heat removal source and the thermally conductive plate.Type: GrantFiled: April 30, 2010Date of Patent: April 22, 2014Assignee: Zeltiq Aesthetics, Inc.Inventors: Mark Baker, Joseph Coakley, Paul William Martens, Albert L. Ollerdessen, William Patrick Pennybacker, Jesse Nicasio Rosen, Peter Yee, John W. Allison, Bryan Weber
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Patent number: 8676338Abstract: Systems and methods that enable delivery of radiofrequency energy and cryotherapy applications to adipose tissue for reduction and contouring of body fat are described herein. Aspects of the disclosure are directed to methods for reducing surface irregularities in a surface of a subject's skin resulting from an uneven distribution of adipose tissue in the subcutaneous layer. The method can include delivering capacitively coupled or conductively coupled radiofrequency energy to a target region of the subject at a frequency which selectively heats fibrous septae in a subcutaneous layer of the target region to a maximum temperature less than a fibrous septae denaturation temperature. Furthermore, the method can include removing heat such that lipid-rich lobules in the subcutaneous layer are affected while non-lipid-rich cells and lipid-rich regions adjacent to the fibrous septae are not substantially affected.Type: GrantFiled: July 20, 2010Date of Patent: March 18, 2014Assignee: Zeltiq Aesthetics, Inc.Inventor: Mitchell E. Levinson
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Publication number: 20140067025Abstract: A system is described for removing heat from a subject's subcutaneous lipid-rich regions, such as tissues, organs, cells, and so forth. In various embodiments, the system includes a controller, a computing device, a data acquisition device, a chiller, and one or more applicators. The system can employ these components to receive a selection of a treatment profile and apply the selected treatment using an applicator. The treatment profile may be received from a patient protection device that connects to an applicator.Type: ApplicationFiled: August 6, 2013Publication date: March 6, 2014Applicant: ZELTIQ AESTHETICS, INC.Inventors: Mitchell E. Levinson, Jesse Nicasio Rosen, Corydon A. Hinton
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CRYOPROTECTANT FOR USE WITH A TREATMENT DEVICE FOR IMPROVED COOLING OF SUBCUTANEOUS LIPID-RICH CELLS
Publication number: 20140005760Abstract: A cryoprotectant for use with a treatment device for improved removal of heat from subcutaneous lipid-rich cells of a subject having skin is provided. The cryoprotectant is a non-freezing liquid, gel, or paste for allowing pre-cooling of the treatment device below 0° C. while preventing the formation of ice thereon. The cryoprotectant may also prevent freezing of the treatment device to the skin or ice from forming from moisture seeping out from the skin. The cryoprotectant may further be hygroscopic, thermally conductive, and biocompatible.Type: ApplicationFiled: January 22, 2013Publication date: January 2, 2014Applicant: ZELTIQ AESTHETICS, INC.Inventors: Mitchell E. Levinson, Donald Johnson, Jessica Preciado, Edward A. Ebbers, Daniel Bucks -
Patent number: 8603073Abstract: Systems for removing heat from a subject's subcutaneous lipid-rich regions, such as tissue, organs, cells, and so forth, are described herein. In various embodiments, the system includes a treatment device and a controller for controlling a treatment process. The controller is configured to detect and compensate for an interruption in the treatment process.Type: GrantFiled: December 17, 2008Date of Patent: December 10, 2013Assignee: Zeltiq Aesthetics, Inc.Inventor: John W. Allison
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Publication number: 20130245731Abstract: Systems for removing heat from a subject's subcutaneous lipid-rich regions, such as tissue, organs, cells, and so forth, are described herein. In various embodiments, the system includes a treatment device and a controller for controlling a treatment process. The controller is configured to detect and compensate for an interruption in the treatment process.Type: ApplicationFiled: May 6, 2013Publication date: September 19, 2013Applicant: ZELTIQ AESTHETICS, INC.Inventor: John W. Allison
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Patent number: 8523927Abstract: A system is described for removing heat from a subject's subcutaneous lipid-rich regions, such as tissues, organs, cells, and so forth. In various embodiments, the system includes a controller, a computing device, a data acquisition device, a chiller, and one or more applicators. The system can employ these components to receive a selection of a treatment profile and apply the selected treatment using an applicator. The treatment profile may be received from a patient protection device that connects to an applicator.Type: GrantFiled: July 13, 2007Date of Patent: September 3, 2013Assignee: Zeltiq Aesthetics, Inc.Inventors: Mitchell E. Levinson, Jesse N. Rosen, Corydon A. Hinton
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Publication number: 20130158636Abstract: A cooling device for removing heat from subcutaneous lipid-rich cells of a subject having skin is provided. The cooling device includes a support having a first portion and a second portion. A first cooling element having a first heat exchanging surface is located at the first portion of the support. A second cooling element having a second heat exchanging surface is located at the second portion of the support. At least one of the first and second cooling elements is movable along the support and is configured to rotate for adjusting an angle between the first and second heat exchanging surfaces.Type: ApplicationFiled: September 14, 2012Publication date: June 20, 2013Applicant: Zeltiq Aesthetics, Inc.Inventors: Joseph Ting, Samuel W. Tolkoff, Timothy Robinson, Richard Wisdom
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Publication number: 20130158440Abstract: Methods and system for treatment planning for non- and minimally-invasive alteration of body adipose tissue for reduction and contouring of body fat are described herein. Treatment plans can be generated by capturing current body part data (e.g., positioning, contour/shape, thickness of adipose tissue, etc.), determining desired outcome of treatment (e.g., percent reduction of adipose tissue thickness, degree of contour change, etc.), and determining treatment parameters to achieve desired results. Algorithms can be used to determine best-fit treatment parameters to use in treatment sessions. In some embodiments, the system can provide a predictive end-result image for communication to patient and/or for determining alteration of desired outcome. In various embodiments, real-time monitoring of feedback data can be used to determine treatment plan efficacy.Type: ApplicationFiled: August 17, 2012Publication date: June 20, 2013Applicant: Zeltiq Aesthetics, Inc.Inventor: John W. Allison
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Publication number: 20130116758Abstract: A system and method of monitoring, controlling and/or detecting events during the removal of heat from subcutaneous lipid-rich tissue is described. In some examples, the system detects an increase in temperature at a treatment device in contact with the skin of a subject, determines that the increase in temperature is related to a treatment event, and performs an action based on the determination. In some examples, the system shuts off the treatment device, alerts an operator, or reduces the cooling in response to a determined treatment event.Type: ApplicationFiled: September 14, 2012Publication date: May 9, 2013Applicant: Zeltiq Aesthetics, Inc.Inventors: Mitchell E. Levinson, Jesse N. Rosen, Corydon A. Hinton, Kevin S. Springer
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Publication number: 20130116759Abstract: A cooling device for removing heat from subcutaneous lipid-rich cells of a subject having skin is provided. The cooling device includes a plurality of cooling elements movable relative to each other to conform to the contour's of the subject's skin. The cooling elements have a plurality of controllable thermoelectric coolers. The cooling elements can be controlled to provide a time-varying cooling profile in a predetermined sequence, can be controlled to provide a spatial cooling profile in a selected pattern, or can be adjusted to maintain constant process parameters, or can be controlled to provide a combination thereof.Type: ApplicationFiled: September 14, 2012Publication date: May 9, 2013Applicant: Zeltiq Aesthetics, Inc.Inventors: Mitchell Levinson, Jesse N. Rosen, William Pennybacker
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Patent number: 8435230Abstract: Systems for removing heat from a subject's subcutaneous lipid-rich regions, such as tissue, organs, cells, and so forth, are described herein. In various embodiments, the system includes a treatment device and a controller for controlling a treatment process. The controller is configured to detect and compensate for an interruption in the treatment process.Type: GrantFiled: December 17, 2008Date of Patent: May 7, 2013Assignee: Zeltiq Aesthetics, Inc.Inventor: John W. Allison
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Publication number: 20130079684Abstract: A treatment device for removing heat from subcutaneous lipid-rich cells of a subject having an actuator that provides mechanical energy to the tissue. The mechanical energy provided may include a vibratory component that can range between low and ultra-high frequencies, and such energy may include various combinations of two or more frequencies tailored to produce the desired effect on the subcutaneous tissue. Disruption of adipose tissue cooled by an external treatment device may be enhanced by applying mechanical energy to cooled tissue. Furthermore, such mechanical energy may impart a vibratory effect, a massage effect, a pulsatile effect, or combinations thereof on the tissue.Type: ApplicationFiled: September 14, 2012Publication date: March 28, 2013Applicant: Zeltiq Aesthetics, Inc.Inventors: Jesse N. Rosen, Mitchell E. Levinson
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Publication number: 20130066309Abstract: Methods are provided herein for affecting a region of a subject's body, comprising exposing the region to a cooling element under conditions effective to cool subcutaneous adipose tissue in said region; and increasing the blood flow rate to the cooled tissue by exposing the tissue to an energy source. Methods are also provided for treating subcutaneous adipose tissue in a region of a subject's body, comprising exposing said region to a cooling element under conditions effective to cool said tissue; and exposing the tissue to an energy source to increase the blood flow rate to the cooled tissue, thereby stimulating reperfusion in, and/or causing an ischemia-reperfusion injury to, the cooled tissue.Type: ApplicationFiled: May 15, 2012Publication date: March 14, 2013Applicant: Zeltiq Aesthetics, Inc.Inventor: Mitchell E. Levinson
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Patent number: 8337539Abstract: A cooling device for removing heat from subcutaneous lipid-rich cells of a subject having skin is provided. The cooling device includes a support having a first portion and a second portion. A first cooling element having a first heat exchanging surface is located at the first portion of the support. A second cooling element having a second heat exchanging surface is located at the second portion of the support. At least one of the first and second cooling elements is movable along the support and is configured to rotate for adjusting an angle between the first and second heat exchanging surfaces.Type: GrantFiled: November 9, 2010Date of Patent: December 25, 2012Assignee: Zeltiq Aesthetics, Inc.Inventors: Joseph Ting, Samuel W. Tolkoff, Timothy Robinson, Richard Wisdom
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Patent number: 8285390Abstract: A system and method of monitoring, controlling and/or detecting events during the removal of heat from subcutaneous lipid-rich tissue is described. In some examples, the system detects an increase in temperature at a treatment device in contact with the skin of a subject, determines that the increase in temperature is related to a treatment event, and performs an action based on the determination. In some examples, the system shuts off the treatment device, alerts an operator, or reduces the cooling in response to a determined treatment event.Type: GrantFiled: August 21, 2008Date of Patent: October 9, 2012Assignee: Zeltiq Aesthetics, Inc.Inventors: Mitchell E. Levinson, Jesse N. Rosen, Corydon A. Hinton, Kevin S. Springer