Patents Assigned to Zeria-Shinyaku Kogyo Kabushiki Kaisha
  • Patent number: 4818751
    Abstract: The present invention relates to a cosmetic comprising a neutral polysaccharide obtained from an acid-fast bacterium. This cosmetic smoothly spreads on the skin without sticking to the skin to give moistness to the skin. Furthermore, the cosmetic covers the skin and shows an excellent moisture-retaining action, and exerts an effect of preventing or moderating the rough skin.
    Type: Grant
    Filed: December 11, 1986
    Date of Patent: April 4, 1989
    Assignee: ZEria Shinyaku Kogyo Kabushiki Kaisha
    Inventor: Sachiaki Ibe
  • Patent number: 4746511
    Abstract: A lipopolysaccharide characterized by a polysaccharide portion composed of D-arabinose and D-mannose in a 1:3/4 ration and 37 to 47% of a fatty acid portion having 14-19 carbon atoms bonded to the polysaccharide through an ester linkage. This lipopolysaccharide has physiological activities such as antitumor activity, immunizing activity, cell juvenescent activity, phagocyte activating activity, and infection preventing activity.This lipopolysaccharide is prepared by culturing a Mycobacterium or a Propionibacterium and extracting the lipopolysaccharide from the culture with a non-ionic surface active agent and purifying the extract with a molecular sieve.
    Type: Grant
    Filed: July 28, 1986
    Date of Patent: May 24, 1988
    Assignees: Chisato Maruyama, Zeria Shinyaku Kogyo Kabushiki Kaisha
    Inventors: Hiroshi Kobatake, Takahiro Suekane, Kazuhiro Kumagai, Osamu Ohya
  • Patent number: 4707472
    Abstract: Cycloartenol ferulate/cyclodextrin complex is prepared by including cycloartenol ferulate, which is a component of .gamma.-oryzanol and hardly soluble in water, with cyclodextrin to thereby elevate its solubility in water and improve its absorption through digestive tracts. Thus various pharmaceutical and physiological effects of cycloartenol ferulate are further improved.
    Type: Grant
    Filed: February 28, 1986
    Date of Patent: November 17, 1987
    Assignee: Zeria Shinyaku Kogyo Kabushiki Kaisha
    Inventors: Tetsuya Inagaki, Hidemi Aoki, Hiroyasu Aikawa, Masao Takahashi
  • Patent number: 4610891
    Abstract: A process for sugar-coating a solid preparation such as tablet, pill, granule or grain with a sugar-coating liquid comprising pullulan and/or a water-soluble derivative thereof dissolved in an aqueous solution of sucrose. The solid preparation sugar-coated by the above-mentioned process exhibits an enhanced impact strength and shelf life.
    Type: Grant
    Filed: November 25, 1985
    Date of Patent: September 9, 1986
    Assignee: Zeria Shinyaku Kogyo Kabushiki Kaisha
    Inventors: Yosuke Miyamoto, Hajime Goto, Hiroshi Sato, Hiroshi Okano, Masao Iijima
  • Patent number: 4479937
    Abstract: An anti-inflammatory agent comprising as an active component an inhibitor specifically inhibiting a thiol protease, which is obtained from human urine by extraction and purification. This agent has an action of inhibiting a disease caused by a thiol protease. This anti-inflammatory agent is prepared by a process in which a thiol protease inhibitor is extracted and purified from human urine by adopting in combination at least two treatments selected from a treatment with a molecular filter, a treatment with an ion exchanger, a treatment with an adsorber and an affinity chromatographic treatment.
    Type: Grant
    Filed: August 19, 1983
    Date of Patent: October 30, 1984
    Assignee: Zeria Shinyaku Kogyo Kabushiki Kaisha
    Inventors: Hiroshi Sato, Koji Sasaki, Kaname Takagi, Hajime Hiratani, Yoshikazu Yuki
  • Patent number: 4271150
    Abstract: Disclosed is a urokinase preparation for oral administration which is effective for remedy of thrombosis such as cerebral thrombosis and cardiac infarction. This preparation comprises urokinase and, incorporated therein, glycoprotein.
    Type: Grant
    Filed: March 7, 1979
    Date of Patent: June 2, 1981
    Assignee: Zeria-Shinyaku Kogyo Kabushiki Kaisha
    Inventors: Koji Sasaki, Yasukazu Harada
  • Patent number: 4258030
    Abstract: Disclosed is a urokinase preparation for oral administration which is effective for remedy of thrombosis such as cerebral thrombosis and cardiac infarction. This preparation comprises urokinase and, incorporated therein, an enzyme inhibitor.
    Type: Grant
    Filed: March 7, 1979
    Date of Patent: March 24, 1981
    Assignee: Zeria-Shinyaku Kogyo Kabushiki Kaisha
    Inventors: Koji Sasaki, Yasukazu Harada