Patents Examined by Adam C Milligan
  • Patent number: 10945944
    Abstract: The present disclosure relates to formulation for a teeth-cleaning product and a process for creating the formulation. Coconut milk and citrus pith are mixed into a formulation and heated upon a heat source until substantially boiling. Sodium bicarbonate and sodium carbonate are mixed into the formulation. Next, ethanol and hydrogen peroxide are added to the formulation. The formulation is removed from the heat source, then apple flesh and sodium chloride are added to the formulation. The formulation is allowed to cool. Next, peppermint oil and honey are added.
    Type: Grant
    Filed: September 21, 2017
    Date of Patent: March 16, 2021
    Inventor: Colly A. Burke
  • Patent number: 10925821
    Abstract: The present invention relates to a method for producing a liquid composition for oral cavity in which ?-glycyrrhetinic acid is stably dispersed or dissolved to exhibit an increased transparency and which also can ensure a sufficient amount of ?-glycyrrhetinic acid adsorbed on gingiva, even if the amount of a cationic surfactant or an anionic surfactant is restricted; and such a liquid composition for oral cavity. Specifically, the present invention relates to a method for producing a liquid composition for oral cavity, comprising the following step 1 to step 4: (Step 1) a step of blending water (F) with an organic acid and a salt thereof (E) to adjust the pH of a resultant mixture to 5 or more and 6.8 or less, (Step 2) a step of blending 0.02% by mass or more and 0.1% by mass or less of cetylpyridinium chloride (B) into the mixture, (Step 3) a step of blending 0.02% by mass or more and 0.
    Type: Grant
    Filed: December 22, 2015
    Date of Patent: February 23, 2021
    Assignee: KAO CORPORATION
    Inventor: Takeshi Mizumoto
  • Patent number: 10857102
    Abstract: The invention provides multilayer tablets that contain rilpivirine hydrochloride, emtricitabine, and tenofivir disoproxil fumarate. The tablets are useful for the treatment of HIV.
    Type: Grant
    Filed: November 18, 2011
    Date of Patent: December 8, 2020
    Assignees: Gilead Sciences, Inc., Janssen Sciences Ireland UC
    Inventors: Reza Oliyai, Lauren Wiser, Mark Menning
  • Patent number: 10799449
    Abstract: A method is provided of making a medicinal delivery system which satiates a craving in an individual when the medicinal delivery system is administered orally to the individual. A coating composition is applied on a saliva-soluble powder to establish a coated powder, the coating composition featuring an at least partially solubilized craving satiation medicinal compound. The coated powder is combined with an edible carrier base to establish a medicinal delivery system that rapidly releases medicine and buffer preferably followed by slower, sustained release.
    Type: Grant
    Filed: February 4, 2014
    Date of Patent: October 13, 2020
    Assignee: JSRNTI, LLC
    Inventors: Tommy L. Chau, John M. Pinney, Jack E. Henningfield, Edward J. Cone, Saul M. Shiffman, Joseph G. Gitchell
  • Patent number: 10722533
    Abstract: Provided are nutritional supplements designed for enhancing the growth, particularly the linear growth, of pre-pubertal children with a stature measure short compared to the norm. The nutritional composition includes an energy source, arginine and a combination of micronutrients.
    Type: Grant
    Filed: January 22, 2018
    Date of Patent: July 28, 2020
    Assignee: NG Solutions LTD
    Inventors: Moshe Phillip, Michal Yackobovitch-Gavan, Raanan Shamir, Hadassa Bymel, Liora Lazar
  • Patent number: 10716874
    Abstract: A soft film, a sponge, or a sheet in the dried state is provided, which is capable of forming a hydrogel absorbing water or blood. The film is obtainable by preparing a film-state material in the dried state from either a solution of poly(acrylic acid) or a solution of polyvinylpyrrolidone, and bringing the film-state material into contact with the other remaining solution, and then drying or freeze-drying it.
    Type: Grant
    Filed: June 23, 2017
    Date of Patent: July 21, 2020
    Inventor: Yoshiyuki Koyama
  • Patent number: 10688046
    Abstract: The invention relates to stable vancomycin hydrochloride powder for oral liquid formulations. Also provided herein are methods of using vancomycin oral liquid formulations for the treatment of certain diseases such as Clostridium difficile pseudomembranous colitis and Staphylococcal enterocolitis as well as kits and related products thereof.
    Type: Grant
    Filed: November 6, 2019
    Date of Patent: June 23, 2020
    Assignee: CutisPharma, Inc.
    Inventors: Indu Muni, Peter Mione, Anisa Gandhi, Cristina LeChiara
  • Patent number: 10660338
    Abstract: Solid disinfectant dosage forms having a peroxy activator and a peroxy compound are provided. The dosage form can be selected so that addition of the dosage form to a predetermined quantity of water produces a disinfectant solution containing peracetic acid in a concentration of at least about 1000 ppm. The dosage form can include a colour indicator arranged to provide a first colour signal when the concentration of peracetic acid is lower than about 1000 ppm and a second colour signal when the concentration is higher than about 1000 ppm and a third colour signal when the concentration falls below about 1000 ppm. The peroxy compound can be selected from the group consisting of sodium percarbonate, ammonium persulphate, calcium percarbonate, magnesium percarbonate, sodium perborate, sodium persulfate, sodium perphosphate and mixtures thereof.
    Type: Grant
    Filed: January 14, 2015
    Date of Patent: May 26, 2020
    Assignee: PERACIDE (UK) LIMITED
    Inventor: Michael Joseph
  • Patent number: 10626545
    Abstract: The present invention relates to a polymeric material having one or more nanoparticles embedded within the surface layer of a single side of the material. In some embodiments, the nanoparticles are microbiocidal nanoparticles which impart antimicrobial characteristics to the polymeric material within which they sprayed and pushed by are embedded.
    Type: Grant
    Filed: March 16, 2012
    Date of Patent: April 21, 2020
    Assignees: University of Limerick, Wroclaw Medical University, Wroclaw University of Technology
    Inventors: Tofail Syed, Jacek Zeglinski, Patrick Cronin, Halina Podbielska, Ewa Dworniczek, Peter Tiernan, Roman Franiczek, Igor Buzalewicz, Magdalena Wawrzynska
  • Patent number: 10617563
    Abstract: A prosthesis comprising a water-dissolvable coating. A prosthesis for a lacrimal canaliculus comprising a swellable punctal plug with a proximal end and a distal end, with the plug comprising a water-dissolvable biocompatible coating on the distal and/or the proximal end. Materials and methods for making and using the same. A prosthesis for placement in or across natural or prosthetic lumens, ostia, ducts, sinus, or sphincters, the prosthesis comprising a coating. The prosthesis can further provide a depot for sustained drug delivery to tissue.
    Type: Grant
    Filed: July 22, 2016
    Date of Patent: April 14, 2020
    Assignee: Incept, LLC
    Inventors: Peter Jarrett, Amarpreet S. Sawhney, Michael J. McGrath, Arthur Driscoll, Ankita D. Desai, Michael Bassett
  • Patent number: 10610479
    Abstract: The present invention provides cosmetic formulations for improving the appearance of the skin, particularly the lips. The compositions of the invention provide multiple enhanced technologies that work synergistically to enhance hydration and appearance of the skin. Anti-aging peptides and tissue respiratory factor work together in an HA rich environment to enhance collagen and elastin while beneficial antioxidants protect HA in the lip from damaging exposure.
    Type: Grant
    Filed: August 7, 2017
    Date of Patent: April 7, 2020
    Assignee: Jan Marini Skin Research
    Inventors: Jan L. Marini, Subhash J. Saxena
  • Patent number: 10583146
    Abstract: The invention relates to glucocorticoid replacement therapy and provides pharmaceutical compositions and kits designed to deliver one or more glucocorticoids to a subject in need thereon in a manner that results in serum levels of the glucocorticoid that essentially mimic that of a healthy subject for a clinically relevant period of time. The pharmaceutical compositions and kits are prepared in such a way that a first part of one or more glucocorticoids is substantially immediately released and a second part of one or more glucocorticoids is released over an extended period of time of at least about 8 hours. The invention also relates to a method for treating diseases requiring glucocorticoid treatment such as in subjects having a glucocorticoid deficiency disorder.
    Type: Grant
    Filed: April 17, 2014
    Date of Patent: March 10, 2020
    Assignee: SHIRE VIROPHARMA INCORPORATED
    Inventors: Stanko Skrtic, Jörgen Johnsson, Hans Lennernäs, Thomas Hedner, Gudmundur Johannsson
  • Patent number: 10584307
    Abstract: The use of poly(oxyethylene)-poly(oxybutylene) block copolymers in pharmaceutical compositions useful for modifying the surfaces of contact lenses and other medical devices is disclosed. The present invention is based in-part on a discovery that this class of compounds is particularly efficient in wetting hydrophobic surfaces, such as the surfaces of silicone hydrogel contact lenses and other types of ophthalmic lenses. Such compounds are also useful for cleaning purposes. The use of the compounds as surfactants in various types of compositions for treating contact lenses therefore represents a preferred embodiment of the present invention.
    Type: Grant
    Filed: January 5, 2017
    Date of Patent: March 10, 2020
    Assignee: Alcon Inc.
    Inventors: Howard Allen Ketelson, Nathaniel D. McQueen
  • Patent number: 10555914
    Abstract: Various aspects of this patent document relate to methods to produce compositions comprising anionic cannabinoid molecules.
    Type: Grant
    Filed: June 13, 2019
    Date of Patent: February 11, 2020
    Assignee: Natural Extraction Systems, LLC
    Inventor: Douglas G. Metcalf
  • Patent number: 10548874
    Abstract: The present invention relates to a phosphate adsorbent on the basis of maghemite or maghemite/magnetite comprising (i) an iron oxide core comprising a crystal structure of inverse spinel iron oxide, (ii) a coating selected from monomeric carbohydrates, in particular monosaccharides or disaccharides, alditols, or mixtures thereof, and/or (iii) a pharmaceutical excipient selected from polymeric carbohydrates, wherein the phosphate adsorbent has the form of nanoparticles with a particle size of the iron oxide core (i) of less than 20 nm. The present invention further relates to a method for the production of a phosphate adsorbent on the basis of maghemite or maghemite/magnetite, to pharmaceutical compositions comprising the phosphate adsorbent, and to medical uses thereof, especially for the prevention and/or treatment of hyperphosphatemia.
    Type: Grant
    Filed: March 7, 2014
    Date of Patent: February 4, 2020
    Assignee: CHARITE-UNIVERSITATSMEDIZIN BERLIN
    Inventors: Susanne Wagner, Matthias Taupitz, Eyk Schellenberger, Jorg Schnorr, Monika Ebert, Gesche Genter, Harald Kratz
  • Patent number: 10548323
    Abstract: The invention relates to a method for fighting mold, algae, and other microorganisms on various wall, floor, or ceiling surfaces infested with said organisms, and on masonry in general. The method comprises the following steps carried out consecutively: applying a first solution to the infested surface, wherein the first solution contains at least one surfactant compound; applying at least once a second solution that was basified by means of caustic soda to the infested surface, wherein the solution contains at least one hypochlorite compound; applying a third solution to the infested surface, wherein the solution contains at least hydrogen peroxide and lactic acid as active substances, and wherein the application of the third solution is continued until the foam formation on the infested surface has ended; applying a fourth solution to the infested surface, wherein the solution contains at least one quaternary ammonium compound.
    Type: Grant
    Filed: April 8, 2015
    Date of Patent: February 4, 2020
    Assignee: BMB GEBAEUDEHYGIENE GMBH
    Inventor: Gerhard Brandner
  • Patent number: 10525008
    Abstract: The invention relates to a microencapsulated amino acid composition and methods of manufacturing this composition. Amino acids, such as branched-chain amino acids, have low water solubility, poor hydrophilicity, and poor stability. Amino acids are thus difficult to be digested and absorbed. Consequently amino acids can hardly meet human needs of consuming. This microencapsulated amino acid composition that can quickly disperse and dissolve in cold water, resulting clear solution. The method includes (1) adding coating agents, wetting agents, or other excipients to the amino acid mixture, (2) modifying the surface of microencapsulated particles to considerably accelerate the wetting speed. In this composition, the weight ratio of amino acids and excipients is from 100/0.1 to 100/10.0.
    Type: Grant
    Filed: October 11, 2013
    Date of Patent: January 7, 2020
    Assignee: INNOBIO CORPORATION LIMITED
    Inventors: Wenzhong Wu, Jianbin Chen, Yuemei Zhang
  • Patent number: 10493028
    Abstract: The invention relates to stable vancomycin hydrochloride powder for oral liquid formulations. Also provided herein are methods of using vancomycin oral liquid formulations for the treatment of certain diseases such as Clostridium difficile pseudomembranous colitis and Staphylococcal enterocolitis as well as kits and related products thereof.
    Type: Grant
    Filed: October 24, 2017
    Date of Patent: December 3, 2019
    Assignee: CutisPharma, Inc.
    Inventors: Indu Muni, Peter Mione, Anisa Gandhi, Cristina LeChiara
  • Patent number: 10470986
    Abstract: Provided herein are methods and compositions comprising resorcinol derivatives for the use of treating, regulating or preventing a skin condition characterized by oxidative stress or a degenerative process. Methods of preventing, lightening or reducing the appearance of visible discontinuities of the skin resulting from skin pigmentation, skin aging, or other disorders are also disclosed.
    Type: Grant
    Filed: March 6, 2014
    Date of Patent: November 12, 2019
    Assignee: Conopco, Inc.
    Inventors: Andrew W Hinman, Dana Davis, Viktoria Kheifets
  • Patent number: 10471088
    Abstract: This invention relates to solid oral compositions based on SAMe and/or NADH or their salts in association with calcium oxide and/or calcium hydroxide and a process for obtaining them. This invention also relates to a method for stabilising a solid oral composition based on SAMe and/or NADH or their salts, making use of calcium oxide, calcium hydroxide optionally in association with malic acid, glutamic acid, xylitol, calcium sulphate hemihydrate, magnesium oxide and/or mixtures thereof. This invention also relates to the use of SAMe or its salts in association with calcium oxide and/or calcium hydroxide with the possible further addition of melatonin and/or 1-theanine and/or 1-tryptophan and/or 5-hydroxytryptophan for the treatment of depressive states.
    Type: Grant
    Filed: May 21, 2015
    Date of Patent: November 12, 2019
    Assignee: GNOSIS SPA
    Inventors: Daniele Giovannone, Carlo De Angelis