Abstract: Disclosed herein is a method for multimodal imaging during a medical procedure using magnetic resonance imaging (MRI) and Raman optical imaging which involves administering an MRI imaging contrast agent that a chemical structure having charge-transfer electronic transitions. The tissue is imaged using and MRI device and the tissue is illuminated with excitation light that has spectral components that are approximately tuned close to one of the charge-transfer electronic transitions thereby producing enhanced Raman optical signals which are analyzed to produce Raman imaging data followed by registering the MRI and Raman imaging data. The present disclosure also provides a method for ionizing laser plumes through atmospheric pressure chemical ionization.

Abstract: A catheter that comprises a catheter configured for housing at least a portion of a catheter configured for insertion into a body lumen in proximity of a targeted anatomical site and having an imager at a distal end thereof and an adjustable chamber configured for covering the imager. The catheter is configured for introducing a wave conductive medium to the adjustable chamber to increase wave conductivity between the targeted anatomical site and the imager.

Abstract: Systems and methods for harmonic shear wave detection using low frame rate ultrasound, or a three-dimensional (3D) volumetric scan, are provided. As one example, spurious motion sources, such as intrinsic tissue motion and waves that are not at the incident wave harmonic frequency, are removed based on a scanning sequence in which repeated acquisitions from a given subvolume occur closely in time so as to render effects of the spurious motions negligible. As another example, sampling frequency and center frequency are selected such that the spurious motion signal spectra do not overlap with aliased shear wave motion spectra, such that the spurious motions can be filtered.

Abstract: A system for characterizing tissue includes a probe that delivers a continuous and periodic mechanical vibration to a tissue of a subject; an ultrasound emitter that emits a sequence of ultrasound shots and an ultrasound receiver that receives corresponding echo signals to track how the tissue is moved by the periodic mechanical vibration delivered to the tissue; and a control module programmed to provide homogeneity information to an operator of the system, the homogeneity information being determined from at least some of the echo signals and being representative of the ability of the tissue to transmit elastic waves and of the homogeneity of the tissue with respect to the propagation of elastic waves.

Abstract: Imaging devices, systems, and methods are provided. Some embodiments of the present disclosure are particularly directed to imaging a region of interest in tissue with photoacoustic and ultrasound modalities. In some embodiments, a medical sensing system (100) includes a measurement apparatus (102) configured to be placed within a vascular pathway. The measurement apparatus may include a sensor array (106) comprising two or more sensor modalities. The sensor array may be configured to receive sound waves created by the interaction between emitted optical pulses and tissue, transmit and receive ultrasound signals, and rotate around a longitudinal axis of the measurement device. The medical sensing system may also include a processing engine operable to produce images of the region of interest and a display configured to visually display the image of the region of interest.

Abstract: A medical device deployment system includes a main body (101) and a guidewire (103) capable of being passed through the main body and including a lumen. An optical shape sensing (OSS) system (104) is configured to pass through the lumen in the guidewire. The OSS system is configured to measure shape, position or orientation of an endograft (102) relative to a blood vessel for placement of the endograft.

Abstract: A hand-held ultrasound system includes integrated electronics within an ergonomic housing. The electronics includes control circuitry, beamforming and circuitry transducer drive circuitry. The electronics communicate with a host computer using an industry standard high speed serial bus. The ultrasonic imaging system is operable on a standard, commercially available, user computing device without specific hardware modifications, and is adapted to interface with an external application without modification to the ultrasonic imaging system to allow a user to gather ultrasonic data on a standard user computing device such as a PC, and employ the data so gathered via an independent external application without requiring a custom system, expensive hardware modifications, or system rebuilds.

Abstract: Systems and methods of ultrasound imaging of an object that includes multiple depth zones. Each of the zones can be imaged using a different frequency, or the same frequency as another zone. A method includes imaging a first zone using plane wave imaging, imaging a second zone using tissue harmonic imaging, and imaging a third zone using fundamental and subharmonic deep imaging. The depth of each zone can vary based on the ultrasonic array, and correspondingly, the F # used for imaging the zone. In an example, zones can be imaged at different F #'s, for example, at F #1 for the first zone, at F #2, F #3, or F #6 for one or more zones that extend deeper into the object than the first zone. The method can also include forming an image based on the received signals from the multiple zones, and blending the transitions between the zones.

Abstract: Disclosed is a blood flow measurement apparatus using Doppler ultrasound.

Abstract: The present disclosure describes ultrasound imaging systems and methods, which may enable the automatic identification of an image plane in a pre-operative volume corresponding to a real-time image of a moving region of interest. An example method includes receiving real-time ultrasound image data from a probe associated with a position-tracking sensor, generating real-time images based on the real-time ultrasound data and deriving a motion model from the real-time ultrasound image data. The method may further include automatically identifying an image plane in a pre-operative data set to correspond to the real-time ultrasound image by correcting for motion-induced misalignment between the real-time data and the pre-operative data.

Abstract: This device (2) for generating ultrasonic waves in a target region of a soft solid, includes at least two ultrasound sources (32), light sources (40) distributed around a central axis (X2) of the device (2), for enlightening a zone of the soft solid via subsurface scattering, and a video camera (50), for capturing images of the zone enlightened by the lighting means. The ultrasound source (32), the light sources (40) and the video camera (50) are mounted on a body of the device (20) and oriented toward a common target zone which includes a focal point of the ultrasound sources (32). A boresight of the video camera is aligned on the central axis (X2).

Abstract: A biopsy device includes an elongated handle body having a proximal end portion and a distal end portion, a needle disposed within the handle body, first and second transducers, and a display. The needle is configured to move between a retracted position and a deployed position. The first and second ultrasound transducers are disposed within the distal end portion of the handle body. The first and second ultrasound transducers are angled relative to one another and define a space therebetween configured for passage of the needle.

Abstract: A contrast-enhanced digital tomosynthesis system with a source configured to emit penetrating particles toward an object, a detector configured to acquire a series of projection images of the object in response to the penetrating particles from the source, a positioning apparatus configured to position the source relative to the object and the detector, and an imaging system coupled to the source, the detector, and the positioning apparatus. The imaging system is configured to control the positioning apparatus to position the source and detector relative to the object, control the source and the detector to acquire the series of projection images, and construct a tomographic volume capable of exhibiting super-resolution morphology and contrast-enhancement arising from injection of an exogenous contrast agent from data representing the acquired series of projection images or a subset thereof.

Abstract: The position and orientation of an ultrasound probe is tracked in three dimensions to provide highly-accurate three-dimensional bone surface images that can be used for anatomical assessment and/or procedure guidance. The position and orientation of a therapy applicator can be tracked in three dimensions to provide feedback to align the projected path of the therapy applicator with a desired path for the therapy applicator or to provide feedback to align the potential therapy field of a therapy applicator with a target anatomical site. The three-dimensional bone surface images can be fit to a three-dimensional model of the anatomical site to provide or display additional information to the user to improve the accuracy of the anatomical assessment and/or procedure guidance.

Abstract: An ultrasound diagnostic apparatus 1 includes an image acquisition unit 3 that generates an ultrasound image, an image recognition unit 9 that performs image recognition for the ultrasound image to calculate recognition scores, an index value calculation unit 10 that calculates index values of a plurality of parts on the basis of the recognition scores calculated for a predetermined number of ultrasound images, a part narrowing-down unit 11 that narrows down target parts for which part determination is to be performed, from the plurality of parts on the basis of the index values, and a part determination unit 12 that determines an imaging part of the subject on the basis of the recognition scores calculated by the image recognition unit 9 for the target parts narrowed down by the part narrowing-down unit 11.

Abstract: A watch having a cover is described. An optical sensor subsystem is attached adjacent to or directly on an interior surface of the cover. In some cases, the optical sensor subsystem includes a substrate to which a light emitter and a light receiver are attached. The light receiver is configured to receive light emitted by the light emitter and reflected from the skin of a person that wears the watch. In some cases, the light emitter and light receiver are separated by a light-blocking wall that abuts the interior surface of the cover. In some cases, a light filter is attached adjacent or directly on the interior surface of the cover, between the cover and the light receiver.

Abstract: A delta-relaxation magnetic resonance imaging (DREMR) system is provided. The system includes a main field magnet and field shifting coils. A main magnetic field with a strength B0 can be generated using the main filed magnet and the strength B0 of the main magnetic field can be varied through the use of the field-shifting coils. The DREMR system can be used to perform signal acquisition based on a pulse sequence for acquiring at least one of T2*-weighted signals imaging; MR spectroscopy signals; saturation imaging signals and MR signals for fingerprinting. The MR signal acquisition can be augmented by varying the strength B0 of the main magnetic field for at least a portion of the pulse sequence used to acquire the MR signal.

Abstract: A method of processing cardiac ultrasound data for determining information about a mechanical wave in the heart. The method comprises receiving data representative of a time series of three-dimensional data frames, generated from ultrasound signals from a human or animal heart, each frame comprising a set of voxels, each voxel value representing an acceleration component of a respective location in the heart at a common time. The method also comprises identifying, for each voxel, a frame of the series in which the voxel value is at a maximum. A three-dimensional time-propagation data set is generated by assigning each voxel a value representative of the time of the respective frame in the time series for which the corresponding voxel is at a maximum. The method then comprises generating data representative of a three-dimensional velocity vector field by calculating time derivatives from the three-dimensional time-propagation data set.

Abstract: An apparatus includes a processor and a non-transitory memory. The processor is configured to receive pre-operative patient specific data. The pre-operative patient specific data is inputted to a first machine learning model to determine a first predicted post-operative joint performance data output including first predicted post-operative outcome metrics. A reconstruction plan of the joint of the patient is generated based on a medical image of the joint, and at least one arthroplasty surgical parameter obtained from the user. The at least one arthroplasty surgical parameter is inputted into a second machine learning model to determine a second predicted post-operative joint performance data output including second predicted post-operative outcome metrics.

Abstract: A method and ultrasound imaging system for performing an ultrasound examination. The method and system includes entering a workflow and displaying a plurality of graphical icons positioned on a graphical model. The method and system includes selecting a first anatomical zone, acquiring a first image, and saving and associating the first image with the first anatomical zone. The method and system includes saving and associating a first clinical finding with the first anatomical zone. The method and system includes selecting a second anatomical zone, acquiring a second image, and saving and associating the second image with the second anatomical zone. The method and system includes saving and associating a second clinical finding with the second anatomical zone. The method and system include displaying an examination overview including the first image, the first clinical finding, the second image, and the second clinical finding.