Abstract: A device according to some embodiments of the present disclosure includes a housing configured to retain a battery, a primary antenna associated with the housing, and at least one processor in electrical communication with the battery and the primary antenna. In some embodiments, the at least one processor may be configured to cause transmission of a primary signal from the primary antenna to an implantable device during a treatment session of at least three hours in duration, wherein the primary signal is generated using power supplied by the battery and includes a pulse train, the pulse train including a plurality of modulation pulses.

Abstract: Automated treatment of arrhythmia utilizing an electrotherapy device. Time-coordinated applications of medium-voltage therapy (MVT) followed by high-voltage therapy (HVT) include a first MVT waveform to a first target region and a second MVT waveform to a second target region, such that the HVT is synchronized relative to a first compression cycle corresponding to activation of the first target region, and to a second compression cycle corresponding to activation of the second target region resulting from the administration of the MVT.

Abstract: An exemplary method includes 1) detecting, by an external module configured to be positioned external to and worn by a patient, an input audio signal presented to the patient, 2) acoustically transmitting, by the external module, an audio signal representative of the input audio signal, 3) detecting, by an implantable module configured to be implanted within the patient, the acoustically transmitted audio signal, 4) generating, by the implantable module, one or more stimulation parameters based on the acoustically transmitted audio signal, and 5) applying, by the implantable module, electrical stimulation representative of the input audio signal to one or more stimulation sites within the patient in accordance with the one or more stimulation parameters.

Abstract: An electrostimulation system includes a connector connected to an electrostimulation device, a conducting wire pair electrically connected to the connector, an electrical stimulation lead having a sheathing body configured to insulate the conducting wire pair and installed to be inserted into the vein, an electrical stimulus block portion installed at a leading end side of the electrical stimulation lead and having an electrode portion electrically connected to the conducting wire pair and a fixing block configured to bias the electrode portion to the inner wall of the vein, and a rotary member having an engaging groove detachably engaged with the electrical stimulus block portion and configured to rotate the electrical stimulus block portion disposed in the vein about a central axis of the vein disposed in the vein via the engaging groove.

Abstract: A device according to some embodiments may include a housing configured for location external to a body of a subject. The device may also include at least one processor associated with the housing and configured for electrical communication with a power source, and an antenna associated with the at least one processor. The at least one processor may be configured to communicate with an implant circuit located within the body of the subject, cause the implant circuit to receive power in a first power mode and in a second power mode, wherein a first level of power delivered in the first power mode is less than a second level of power delivered in the second power mode, and wherein during a therapy period, power delivery in the first mode occurs over a total time that is greater than about 50% of the therapy period.

Abstract: Described here are devices, systems and methods for forming a fistula between two blood vessels. Generally, the systems may comprise a first catheter which may comprise a fistula-forming element. The fistula-forming element may comprise one or more electrodes, mechanical cutting elements, laser sources, or combinations thereof, and may be used to assist in fistula formation. In some instances, a system may comprise a second catheter, which may comprise a fistula-forming element. One or more of the catheters may comprise one or more markers, magnetic alignment elements, and/or one shape-changing elements.

Abstract: A system for facilitating remote medical diagnosis and consultation of heart disease for a patient, the system comprising: a diagnostic device for performing Electrocardiography on the patient, a network device in communication with the diagnostic device via wired or wireless communication links, a software program pre-installed in the network device, a server located remotely, wherein during operation, the patient activates the diagnostic device which will perform Electrocardiography on the patient, the diagnostic device receives diagnostic data and transmits the diagnostic data to the network device, the software program transmit the diagnostic data to over a network to a server which a physician have access to, and based on the diagnostic data gathered by the server and some additional medical data, the physician can review the patient's health condition and offer an appropriate feedback and diagnosis for the patient.

Abstract: The present invention provides a visual prosthesis comprising: image capture means for capturing an image from a surrounding environment; image processing means for processing the image and converting the image into a transmissible image signal; signal processing means for processing and converting the image signal into a stimulation signal; and a retina stimulation device (10) adapted to stimulate the retina of both left and right eyes in accordance with the stimulation signal. The retina stimulation device (10) comprises a left-side stimulation unit (11) having an electrode array (12) for stimulating the retina of the left eye, and a right-side stimulation unit (11?) having an electrode array (12?) for stimulating the retina of the right eye, with the left-side stimulation unit (11) having a configuration which is reversed with respect to a configuration of the right-side stimulation unit (11?).

Abstract: Highly miniaturized electro-mechanical medical implants for certain applications cannot be fit into the available anatomic space unless their diameter can be made small enough. With devices such as rotary blood pumps or linear actuators, using rotary or linear electric motors, a thin motor stator that provides sufficient power must be encased in a corrosion resistant hermetically sealed enclosure into which electric wires must pass. Hermetic feedthroughs of the prior art are not structurally suited to maximal miniaturization with optimal electrical properties because of the need for welding of ferrules or other support components. The sub-miniature medical implants having the robust feedthrough of the present invention integrate the feedthrough wires, insulators, and sealing within a radially extending flange that is part of the end wall of the motor enclosure. This permits the largest feedthrough wire and thickest insulator to be built into the limited available space.

Abstract: An electrode is provided at a distal end of a catheter and dimensioned for deployment within a renal artery. A deformable cover of the electrode incorporates a force-activatable conduction apparatus. The cover is configured to conduct electrical energy only through a region or regions of the cover subject to deformation due to contact with a wall of the target vessel. The electrical energy is sufficient to ablate perivascular renal nerves proximate the deformed region or regions of the electrode cover. The cover is configured to prevent conduction of electrical energy through the cover in the absence of a deformation force applied to the cover.

Abstract: An anchor sleeve for securing a therapy delivery element, such as a stimulation lead or catheter, within a living body, that includes an inner sleeve with pre-formed locations of weakness that facilitate localized deformation. The anchor includes a deformable outer sleeve with a primary lumen extending along an axis. The outer surface of the outer sleeve includes a plurality of suture grooves oriented generally concentric to the axis. The inner sleeve includes a plurality of beams connected at deflection regions arranged around a secondary lumen. The inner sleeve is located in the primary lumen adjacent to the suture grooves so that the secondary lumen is generally concentric with the primary lumen. A plurality of locations of weakness are preformed in each of the beams to facilitate localized deformation in response to a radially inward force applied around the suture grooves by a suture material.

Abstract: Described here are devices, systems and methods for forming a fistula between two blood vessels. Generally, the systems may comprise a first catheter which may comprise a fistula-forming element. The fistula-forming element may comprise one or more electrodes, mechanical cutting elements, laser sources, or combinations thereof, and may be used to assist in fistula formation. In some instances, a system may comprise a second catheter, which may comprise a fistula-forming element. One or more of the catheters may comprise one or more markers, magnetic alignment elements, and/or one shape-changing elements.

Abstract: Techniques are described for generating electrical stimulation current pulses for delivery of electrical stimulation therapy via a current-controlled system that emulates voltage pulses generated via a voltage-controlled system.

Abstract: Methods of modifying a subject's cognitive state by applying transdermal electrical stimulation (TES). In particular, described herein are methods of applying TES using a pair of electrodes each positioned at a particular location on the skin of the subject's head, or the head and neck, to evoke a predetermined cognitive state using a TES applicator. In particular, described herein are methods of enhancing attention, alertness, or mental focus or of enhancing a calm or relaxed mental state by applying high-intensity TES across electrodes positioned on the subject's temple and either the mastoid region or on the subject's neck. The subject may control the application directly and TES may be applied by a portable, including wearable, TES applicator.

Abstract: A method for detecting an R-wave from an ECG signal derived from a living body, the ECG signal including a plurality of ECG channel signals, the method comprising the steps of providing a plurality of channel R-wave detectors each processing a distinct signal of the plurality of channel ECG signals to generate a distinct channel trigger signal of a plurality of channel trigger signals, and inputting each channel trigger signal into a composite R-wave detector to generate a composite R-wave trigger, whereby the composite R-wave detector more accurately detects R-waves than each of the plurality of channel R-wave detectors.

Abstract: The present disclosure provides a system for oxygenating blood. The system may include an implantable blood pump that may draw a supply of blood from the circulatory system of a mammalian subject, such as a human being. The blood pump may provide the supply of blood to an adaptor, where the supply of blood may be supplied to either or both of a first branch or second branch. The first branch may lead to an external blood oxygenator. The oxygenator may oxygenate the blood, and the blood may be returned to the circulatory system of the mammalian subject. The second branch may bypass the oxygenator and may connect to the circulatory system of the mammalian subject. In this regard, while the blood is supplied to the second branch, the oxygenator may be disconnected and blood may be prevented from entering the first branch.

Abstract: An implantable medical electrical lead includes a plurality of conductors that extend continuously, without any intermediary junctions, between a plurality of electrodes and a corresponding plurality of contact members of an in-line connector terminal. A junction between each conductor and the corresponding contact member is preferably formed by first fitting a conductive sleeve, which is coupled to a proximal portion of the conductor, into an eyelet feature of the contact member, which is mounted on a strut member, and then welding the sleeve to the contact member at a pre-formed slot of the contact member, which extends along an external recessed surface thereof. The assembly of the connector terminal preferably completes the construction of the lead, wherein the proximal portion of each conductor is positioned in a helical path, which extends between an elongate body of the lead and the connector terminal, and along which a grip zone is formed.

Abstract: Effective systems and methods for improving neural communication impairment of a vertebrate being and affecting motor activity of a peripheral body part including a first signal providing component configured to provide pulsed peripheral stimulation signals at the peripheral body part, a second signal providing component configured to provide a pulsed motor cortex stimulation signal to a motor cortex area, a substantially DC signal providing component configured to provide direct current spinal stimulation signal at a neural spinal junction and a controller component configured to control timing of the pulsed peripheral stimulation signals and the pulsed motor cortex stimulation signal.

Abstract: Disclosed is an arrhythmia-diagnosing method and device for diagnosing arrhythmias, such as fibrillation or tachycardia. The arrhythmia-diagnosing method includes the following steps: measuring (a) the heart characteristic length, and the (b) frequency and (c) conduction velocity of the cardiac electrical wave; and (d) determining the occurrence or absence of an arrhythmia by using the three parameters measured in steps (a) to (c). With this invention, it is possible to predict and diagnose an electrical wave tornado, one of the causes of arrhythmia, by using a non-dimensional parameter, to identify patients at risk of death or brain death due to an arrhythmia and to reduce the mortality of patients suffering from arrhythmias significantly.

Abstract: Devices for controlling spinal cord modulation for inhibiting pain, and associated systems and methods, including controllers for automated parameter selection are disclosed. A particular embodiment includes receiving a first input corresponding to a location of a signal delivery device implanted in a patient, establishing a positional relationship between the signal delivery device and an anatomical feature of the patient, receiving a second input corresponding to a medical indication of the patient, and, based at least in part on the positional relationship and the indication, automatically identifying a signal delivery parameter in accordance with which a pulsed electrical signal is delivered to the patient via the signal delivery device.