Patents Examined by Anna Falkowitz
  • Patent number: 9743670
    Abstract: The present invention relates to a method of preparing chlorine dioxide (ClO2) from hydrochloric acid (HCl) and sodium chlorite (NaClO2) in the presence of water (H2O). The invention has for its object to further develop the method such that it is more economical to install and operate. The object is achieved when the hydrochloric acid is used in aqueous solution at a concentration of 27 to 33 wt %, the sodium chlorite is used in aqueous solution at a concentration of 22 to 27 wt % and the molar ratio of hydrochloric acid used to sodium chlorite used is between 2.14 and 4.2.
    Type: Grant
    Filed: October 11, 2012
    Date of Patent: August 29, 2017
    Assignee: Infracor GmbH
    Inventors: Gerda Grund, Hartmut Rahtz, Hermann-Josef Korte
  • Patent number: 9737639
    Abstract: Embodiments of the invention include lubricious medical device coatings. In an embodiment the invention includes a coating for a medical device including a first layer comprising polyvinylpyrrolidone derivatized with a photoreactive group; and a first cross-linking agent comprising at least two photoreactive groups; a second layer disposed on the first layer comprising polyvinylpyrrolidone derivatized with a photoreactive group; a second cross-linking agent comprising at least two photoreactive groups; and a polymer comprising polyacrylamide, the polymer derivatized with at least one photoreactive group. Other embodiments are included herein.
    Type: Grant
    Filed: May 26, 2016
    Date of Patent: August 22, 2017
    Assignee: Surmodics, Inc.
    Inventor: David E. Babcock
  • Patent number: 9737632
    Abstract: A synthetic construct suitable for implantation into a biological organism that includes at least one polymer scaffold; wherein the at least one polymer scaffold includes at least one layer of polymer fibers that have been deposited by electrospinning; wherein the orientation of the fibers in the at least one polymer scaffold relative to one another is generally parallel, random, or both; and wherein the at least one polymer scaffold has been adapted to function as at least one of a substantially two-dimensional implantable structure and a substantially three-dimensional implantable tubular structure.
    Type: Grant
    Filed: September 25, 2014
    Date of Patent: August 22, 2017
    Assignee: NANOFIBER SOLUTIONS, INC.
    Inventors: Jed K. Johnson, Ross Kayuha
  • Patent number: 9726910
    Abstract: Ophthalmic lenses and light filters containing special additives that have fluorescence emission in the near infrared region of wavelengths—in order to enhance phototherapy for the human eye when it is exposed to sunlight and artificial lighting.
    Type: Grant
    Filed: July 14, 2014
    Date of Patent: August 8, 2017
    Assignee: PHOTOPROTECTIVE TECHNOLOGIES INCORPORATED
    Inventor: James Martin Gallas
  • Patent number: 9724078
    Abstract: The present disclosure relates to a method for vacuum expansion of a paste prior to freeze-drying said paste to achieve a dry paste composition which reconstitutes efficiently to form a flowable paste upon addition of an aqueous medium. The present disclosure further relates to a syringe for retaining a dry paste composition in a vacuum.
    Type: Grant
    Filed: June 20, 2014
    Date of Patent: August 8, 2017
    Assignee: Ferrosan Medical Devices A/S
    Inventors: Kristian Larsen, Michael Wrang Mortensen
  • Patent number: 9693553
    Abstract: Storage stable polyhydroxylated aromatic ether adducts of polyalkylene oxide are described. Reactive compositions are formed by combining an ether adduct with an aldehyde, optionally further adding a phenolic-aldehyde prepolymer. The reactive compositions are cured by removing water, by acidification, or both. The cured compositions sorb solvated compounds from environments containing water. The cured compositions are also useful for pre-loading with compounds that are subsequently released at a controlled rate into environments containing water.
    Type: Grant
    Filed: April 21, 2016
    Date of Patent: July 4, 2017
    Assignee: Eco Verde Technologies, Inc.
    Inventor: Curtis Elliott
  • Patent number: 9682063
    Abstract: The present invention provides a novel formulation for cancer treatment and a method for enhancing the HCD's efficacy in cancer treatment. Specifically, the present invention provides copper-modified silica nanoparticles loaded with HCD, which exhibits better efficacy than some conventional anticancer drugs.
    Type: Grant
    Filed: February 25, 2015
    Date of Patent: June 20, 2017
    Assignee: National Dong Hwa University
    Inventors: Ching-Feng Weng, Yi-Chen Chia, Chia-Hung Lee, T. Varadharajan
  • Patent number: 9676946
    Abstract: [Problem] To provide a coating composition, which can reduce a load to the environment and form a cured layer having corrosion resistance, antifouling property and high transparency. [Means for Solution] A coating composition comprising (A) a polysilazane having alkoxy-modified silane group in a side chain, (B) non-reactive polydialkylsiloxane and (C) reactive polydialkylsiloxane, and a obtained cured layer therewith.
    Type: Grant
    Filed: July 1, 2014
    Date of Patent: June 13, 2017
    Assignee: AZ Electronic Materials (Luxembourg) S.A.R.L.
    Inventors: Andre Margaillan, Christine Bressy, Francois-Xavier Perrin
  • Patent number: 9662298
    Abstract: Unique foamable vehicles or carriers comprising at least one wax, waxy substance, counterpart or derivative, a stabilizer, water, and a propellant are provided. In some embodiments, the wax is a liquid wax. In some embodiments, the wax includes a solid wax and a liquid wax. The compositions are substantially free of crystals. The components are selected to provide a composition that is substantially resistant to aging and to phase separation, and/or can substantially solubilize and or stabilize active ingredients. Pharmaceutical and cosmetic compositions with potentially enhanced skin delivery and their uses are also provided.
    Type: Grant
    Filed: January 22, 2014
    Date of Patent: May 30, 2017
    Assignee: FOAMIX PHARMACEUTICALS LTD.
    Inventors: Dov Tamarkin, Rita Keynan, David Schuz, Tal Berman
  • Patent number: 9649336
    Abstract: The present invention is directed to methods and compositions for the treatment or prevention of actinic keratosis and/or for countering the effects of skin aging and/or damage to blood vessels and fine wrinkling The present invention provides for a composition comprising aluminum fluoride or chemical compounds which releases aluminum fluoride to be used to treat or reduce the negative effects of actinic keratosis or sun-induced skin aging and associated conditions, for example, damaged blood vessels and fine wrinkling
    Type: Grant
    Filed: December 16, 2013
    Date of Patent: May 16, 2017
    Inventor: Avi Dascalu
  • Patent number: 9642360
    Abstract: Cationic antimicrobial polymers have been synthesized by a bulk addition polymerization of a nucleophilic agent comprising two tertiary amines and an electrophilic agent that comprises two leaving groups and an aromatic ring between the leaving groups. The reaction solvent for the polymerization is chosen to allow precipitation of the cationic polymer at the polymerization temperature, thereby limiting molecular weight. Quaternization and polymerization occur concurrently. The cationic polymers can be highly active against Gram-negative and Gram-positive microbes, and/or fungi. The cationic polymers can also be non-hemolytic and non-cytotoxic at the effective concentration against the microbes.
    Type: Grant
    Filed: June 25, 2015
    Date of Patent: May 9, 2017
    Assignees: International Business Machines Corporation, Agency For Science, Technology And Research
    Inventors: Julian M. W. Chan, James L. Hedrick, Robert J. Ono, Jye Yng Teo, Yi Yan Yang, Mu San Zhang
  • Patent number: 9622473
    Abstract: A herbicidal composition comprising an aqueous suspension of microcapsules, having a capsule wall of a porous condensate polymer, and containing a solution of fluoroxypyr in a rosin solvent system is provided. A herbicidal composition comprising microcapsules, having a capsule wall of a porous condensate polymer, and containing fluoroxypyr and a solvent comprising rosin and/or a rosin derivative, is also provided. A method of preparing a herbicidal composition is also disclosed, comprising providing a water immiscible phase comprising fluoroxypyr and an isocyanate dissolved in a rosin solvent system comprising rosin and/or a rosin derivative; providing an aqueous phase comprising one or more surfactants; combining the water immiscible phase and the aqueous phase to form a dispersion of the water immiscible phase in the aqueous phase; adding to the resulting dispersion an amine, thereby forming microcapsules of polyurea containing droplets of the water immiscible phase; and curing the microcapsules.
    Type: Grant
    Filed: June 10, 2016
    Date of Patent: April 18, 2017
    Assignee: ROTAM AGROCHEM INTERNATIONAL COMPANY LIMITED
    Inventor: James Timothy Bristow
  • Patent number: 9616020
    Abstract: The invention provides delivery systems comprised of stabilized multilamellar vesicles, as well as compositions, methods of synthesis, and methods of use thereof. The stabilized multilamellar vesicles may comprise prophylactic, therapeutic and/or diagnostic agents.
    Type: Grant
    Filed: April 13, 2016
    Date of Patent: April 11, 2017
    Assignee: Massachusetts Institute of Technology
    Inventors: Darrell J. Irvine, Jaehyun Moon
  • Patent number: 9610238
    Abstract: The invention relates to nail composition sets comprising at least one primer comprising compound(s) other than acrylic latex and at least one color coat comprising at least one acrylic latex and water.
    Type: Grant
    Filed: December 5, 2012
    Date of Patent: April 4, 2017
    Assignee: L'OREAL
    Inventors: Chunhua Li, Hy Si Bui, Jean-Thierry Simonnet
  • Patent number: 9611353
    Abstract: Novel pentablock polymers having a PCL-PLA-PEG-PLA-PCL or PCL-PGA-PEG-PGA-PCL configuration, wherein PEG is polyethylene glycol, PCL is poly(8-caprolactone), PGA is poly(glycolic acid), and PLA is poly(lactic acid), and methods of making nanoparticles from the pentablock polymers, are disclosed. The invention is also directed to a method for preparing nanoparticle compositions comprised of polymers with high levels of bioactive or diagnostic agents.
    Type: Grant
    Filed: May 16, 2014
    Date of Patent: April 4, 2017
    Assignee: THE CURATORS OF THE UNIVERSITY OF MISSOURI
    Inventors: Ashim K. Mitra, Sulabh P. Patel, Ravi D. Vaishya, Vibhuti Agrahari
  • Patent number: 9603868
    Abstract: The present invention is directed to a substantially homogeneous miscible liquid adhesive composition comprising a relatively high number average molecular weight (Mn=6,000-10,000 g/mole) multi-arm star polymer having polyisobutylene chains terminated with cyanoacrylate groups (High-Ø(PIB-CA)3); 2-octyl cyanoacrylate (Oct-CA); and a low boiling point biocompatible solvent having a boiling point of not more than 37° C. When this adhesive composition contacted with living tissue and reacted with a nucleophile, such as water or an initiator, the biocompatible solvent will evaporate and the High-Ø(PIB-CA)3 and Oct-CA will co-polymerize in-situ to form a poly(2-octyl cyanoacrylate)-polyisobutylene co-network suitable for any of a number of biomedical applications, from wound closure and healing of skin tissue, to sealant for surgical cuts.
    Type: Grant
    Filed: November 13, 2015
    Date of Patent: March 28, 2017
    Assignee: The University of Akron
    Inventors: Joseph Kennedy, Istvan Szanka, Amalia Szanka
  • Patent number: 9605012
    Abstract: The described invention provides organometallic complexes capable of spin transfer, comprising at least three different metals and the use of pharmaceutical compositions comprising such complexes in detoxification of reactive oxygen species in inflammatory conditions.
    Type: Grant
    Filed: March 11, 2013
    Date of Patent: March 28, 2017
    Assignee: Garnett McKeen Laboratory, Inc.
    Inventor: Merrill Garnett
  • Patent number: 9597272
    Abstract: The invention relates to nail composition sets comprising at least one primer, at least one bonding composition, and at least one color coat, wherein the primer comprises water and at least one adhesive compound and preferably further comprises at least one water-soluble film forming agent and/or at least one plasticizer.
    Type: Grant
    Filed: December 5, 2012
    Date of Patent: March 21, 2017
    Assignee: L'OREAL
    Inventors: Chunhua Li, Ramakrishnan Hariharan, Jean-Thierry Simonnet, Xianzhi Zhou, Hy Si Bui, Sarah Fairneny
  • Patent number: 9585387
    Abstract: PEHAM dendrimers of the formula: Specific PEHAM dendrimers are used in a formulation with an active agent for agricultural purposes. In particular, the PEHAM dendrimers may be used for increasing the efficacy of the active agent in various ways, such as by improving solubility of the active agent in the formulation, by improving adhesion and penetration of the active agent to plant surfaces, or by improving the water-fastness of the active agent to the plant or seed. The PEHAM dendrimers may also increase the efficacy of the active agent by increasing soil penetration of the active agent to reach the plant roots or under soil parts, by reducing soil adhesion of the active agent to reach the plant roots or under soil parts, or by reducing enzymatic degradation of the active agent by the plant or seed or microorganisms in the soil.
    Type: Grant
    Filed: February 16, 2015
    Date of Patent: March 7, 2017
    Assignee: STARPHARMA PTY LTD
    Inventors: Ryan T. Hayes, David James Owen, Abhay Singh Chauhan, Veera Reddy Pulgam, Harsh Vardhan
  • Patent number: 9580540
    Abstract: The present invention relates to a process for producing a hydroxy amino polymer comprising the steps: a) Reaction of an H functional starter compound bearing at least one Zerewitinoff active H atom with an unsaturated, cyclical carboxylic acid anhydride and at least one alkylene oxide compound for obtaining a prepolymer bearing hydroxyl groups, b) Addition of a primary amine and/or of ammonia to the double bond(s) of the prepolymer bearing hydroxyl groups obtained according to step a) for obtaining the hydroxy amino polymer, wherein the ratio of added amino groups to hydroxyl groups in a hydroxy amino polymer is at least 0.6. Furthermore, the invention relates to a hydroxy amino polymer, which can be achieved according to this process as well as a polyurea/polyurethane system, which contains such a hydroxy amino polymer.
    Type: Grant
    Filed: December 17, 2012
    Date of Patent: February 28, 2017
    Assignee: Adhesys Medical GmbH
    Inventors: Heike Heckroth, Christoph Eggert, Jörg Hofmann, Klaus Lorenz, Edward Browne, Hartmut Nefzger