Patents Examined by Anna Falkowitz
  • Patent number: 9549886
    Abstract: Personal care formulations containing alkyl ketal esters having the structure wherein a is 0 or an integer of 1 to 12; b is 0 or 1; R2 is a divalent C1-8 group optionally substituted with up to 5 hydroxyl groups; and R1 is C1-6 alkyl.
    Type: Grant
    Filed: November 7, 2014
    Date of Patent: January 24, 2017
    Assignee: GFBIOCHEMICALS LIMITED
    Inventors: Dorie J. Yontz, Lee Richard Rieth, Nicholas Morante, Irwin Palefsky
  • Patent number: 9549951
    Abstract: Materials capable of delivering stabilized free radicals to targeted treatment sites. The materials comprise semi-crystalline, hydrolytically degradable polymers that are subjected to ionizing radiation to create stabilized free radicals therein. Upon exposure to oxygen containing aqueous media, the materials generate reactive oxidative species which are useful in biological processes.
    Type: Grant
    Filed: January 12, 2016
    Date of Patent: January 24, 2017
    Assignee: W. L. Gore & Associates, Inc.
    Inventors: Tiffany J. Brown, Adam S. Lafleur, Kenneth Mazich, Jeffrey C. Towler, Ji Zhang
  • Patent number: 9545453
    Abstract: The present invention generally relates to carriers including polymers and lipids that comprise a CXCR4 inhibiting moiety. More specifically, these carriers are biodegradable and can be bioreducible polymers that comprise a CXCR4 inhibiting moiety. These carriers can be suitable for delivery of nucleic acids to cells. These carriers and pharmaceutical compositions can be used to treat various conditions including cancers and inflammation conditions.
    Type: Grant
    Filed: October 15, 2012
    Date of Patent: January 17, 2017
    Assignee: Wayne State University
    Inventors: David Oupicky, Jing Li
  • Patent number: 9517292
    Abstract: A polymer comprising a phosphoryl choline moiety(ies), a composition comprising the polymer and optionally a bioactive agent, an implantable device such as a DES or a non-implantable device such as an angioplasty balloon comprising thereon a coating comprising the polymer and optionally a bioactive agent, and a method of using the device for the treatment of a disorder in a human being are provided.
    Type: Grant
    Filed: January 29, 2014
    Date of Patent: December 13, 2016
    Assignee: Abbott Cardiovascular Systems Inc.
    Inventors: Florian N. Ludwig, John Stankus, Mikael Trollsas
  • Patent number: 9511173
    Abstract: The biocompatible, biodegradable materials in the solid and/or liquid form are based on segmented linear polyurethanes and/or segmented crosslinked polyurethanes based on A) one or more biocompatible polyols susceptible to hydrolytic and/or enzymatic degradation having a molecular weight of 100 to 20,000 dalton and a number of active hydroxyl groups per molecule (functionality) of at least two or higher: B) one or more diisocyanates and/or triisocyanates; and C) one or more low molecular weight chain extenders having a molecular weight of 18 to 1000 dalton and the functionality of at least two or higher.
    Type: Grant
    Filed: May 7, 2015
    Date of Patent: December 6, 2016
    Assignee: DePuy Synthes Products, Inc.
    Inventor: Sylwester Gogolewski
  • Patent number: 9498487
    Abstract: The present invention provides a topical composition comprising (a) at least one delivery agent compound and (b) a cromoglycic acid compound. Methods of treatment, and methods of preparing the topical composition are also provided.
    Type: Grant
    Filed: May 19, 2005
    Date of Patent: November 22, 2016
    Assignee: EMISPHERE TECHNOLOGIES, INC.
    Inventors: Puchun Liu, Steven Dinh, Ehud Arbit, Michael M. Goldberg
  • Patent number: 9486338
    Abstract: Provided herein is a device comprising: a. stent; b. a plurality of layers on said stent framework to form said device; wherein at least one of said layers comprises a bioabsorbable polymer and at least one of said layers comprises one or more active agents; wherein at least part of the active agent is in crystalline form.
    Type: Grant
    Filed: December 9, 2015
    Date of Patent: November 8, 2016
    Assignee: Micell Technologies, Inc.
    Inventors: James B. McClain, Charles Douglas Taylor
  • Patent number: 9469726
    Abstract: Water soluble biodegradable polymers were prepared by an organoacid catalyzed ring opening polymerization (ROP) of a cyclic carbonate monomer bearing an active ester side chain. The initial polymer comprising an active ester side chain was treated with an amino-alcohol, which transformed the active ester groups to N-substituted amide groups bearing mono-hydroxy alkyl groups and/or dihydroxy alkyl groups, thereby forming the water soluble polymers. The water-soluble polymers are non-toxic and exhibit stealth properties in buffered serum solution.
    Type: Grant
    Filed: October 6, 2014
    Date of Patent: October 18, 2016
    Assignees: International Business Machines Corporation, Agency For Science, Technology And Research
    Inventors: Daniel J. Coady, Amanda C. Engler, James L. Hedrick, Xiyu Ke, Yi Yan Yang
  • Patent number: 9468590
    Abstract: The invention relates to a foam formulation comprising a substantially emulsifier-free emulsion of the oil-in-water type, comprising an oil phase and an aqueous phase, the emulsion comprising at least one surface active, ionic polymer with a molecular weight of more than 5000 g/mol, wherein the ionic polymer is a copolymer comprising as monomer units an ionic monomer (M1) and at least one further monomer.
    Type: Grant
    Filed: December 10, 2010
    Date of Patent: October 18, 2016
    Assignee: NEUBOURG SKIN CARE GMBH & CO. KG
    Inventor: Rolf Daniels
  • Patent number: 9457090
    Abstract: Bioactive hydroforming luminal liner compositions are formed of an absorbable crystalline amphiphilic polyether-ester-urethane dissolved in a liquid derivative of a polyether glycol that undergoes transformation into a tissue-adhering, resilient interior cover or liner for the controlled release of its bioactive payload at clinically compromised conduits in humans as in the case of bacteria- and yeast-infected vaginal canals, esophagi, and arteries following angioplasty.
    Type: Grant
    Filed: April 7, 2014
    Date of Patent: October 4, 2016
    Assignee: Poly-Med, Inc.
    Inventors: Shalaby W. Shalaby, David Ingram, Georgios Hilas, Sheila Nagatomi
  • Patent number: 9445879
    Abstract: The invention consists of a rapidly crosslinkable, two-component silicone elastomer together with a specially designed tray that serves as a form for the silicone resin and forms an integral portion of a dental appliance.
    Type: Grant
    Filed: April 13, 2016
    Date of Patent: September 20, 2016
    Assignee: EZ Tray LLC
    Inventors: James V. Crivello, Lewis R. Morrison
  • Patent number: 9445994
    Abstract: The invention provides delivery systems comprised of stabilized multilamellar vesicles, as well as compositions, methods of synthesis, and methods of use thereof. The stabilized multilamellar vesicles comprise terminal-cysteine-bearing antigens or cysteine-modified antigens, at their surface and/or internally.
    Type: Grant
    Filed: June 17, 2015
    Date of Patent: September 20, 2016
    Assignee: Massachusetts Institute of Technology
    Inventors: Darrell J. Irvine, Jaehyun Moon
  • Patent number: 9439416
    Abstract: The present invention relates to compositions comprising terpenes which are particularly suitable for treating plant infections, to methods of making such compositions, and to methods of using them. The present invention also relates to compositions comprising terpenes and hollow glucan particles or cell wall particles and methods for preparing such compositions; such compositions increase terpene stability and activity and provide a suitable carrier for the terpenes. The invention also relates to methods of using such compositions in the medical, veterinary and agricultural fields. In particular, the terpenes disclosed are thymol, eugenol, geraniol, citral and L-carvone.
    Type: Grant
    Filed: August 3, 2006
    Date of Patent: September 13, 2016
    Assignee: Eden Research PLC
    Inventors: Lanny Franklin, Elizabeth Cloud, Lanna Knapp, Gary Ostroff
  • Patent number: 9433516
    Abstract: Provided herein is a device comprising: a. stent; b. a plurality of layers on said stent framework to form said device; wherein at least one of said layers comprises a bioabsorbable polymer and at least one of said layers comprises one or more active agents; wherein at least part of the active agent is in crystalline form.
    Type: Grant
    Filed: April 16, 2010
    Date of Patent: September 6, 2016
    Assignee: Micell Technologies, Inc.
    Inventors: James B. McClain, Douglas Taylor
  • Patent number: 9422278
    Abstract: This document discloses molecules having the following formula (“Formula One”): and processes related thereto.
    Type: Grant
    Filed: February 25, 2015
    Date of Patent: August 23, 2016
    Assignee: Dow AgroSciences LLC
    Inventors: Maurice C. Yap, Ann M. Buysse, Daniel I. Knueppel, Yu Zhang, Negar Garizi, Noormohamed M. Niyaz, Christian T. Lowe, Ricky Hunter, Tony K. Trullinger, David A. Demeter, Dan Pernich, Carl DeAmicis, Ronald Ross, Jr., Timothy C. Johnson
  • Patent number: 9415133
    Abstract: The invention is related to gel preparations capable of absorbing as well as releasing liquid, and the use of such gel preparations in the treatment of wounds.
    Type: Grant
    Filed: October 18, 2013
    Date of Patent: August 16, 2016
    Assignee: Euro-Celtique S.A.
    Inventors: Sabine Scherer, Christian Wagner, Christian Leuner, Wolfgang Fleischer
  • Patent number: 9415143
    Abstract: A biodegradable in vivo supporting device is disclosed. The in vivo supporting device comprises a biodegradable metal scaffold and a biodegradable polymer coating covering at least a portion of the biodegradable metal scaffold, wherein the biodegradable polymer coating has a degradation rate that is faster than the degradation rate of the biodegradable metal scaffold.
    Type: Grant
    Filed: February 4, 2016
    Date of Patent: August 16, 2016
    Assignee: Q3 MEDICAL DEVICES LIMITED
    Inventor: Eric K. Mangiardi
  • Patent number: 9415123
    Abstract: Provided herein are nanobubbles designed for use in ultrasound-mediated ablation of cancer cells. The nanobubbles undergo ultrasound-mediated cavitation at an ablation threshold which is significantly decreased, relative to standard ultrasound-mediated treatment of cancer cells. In exemplary embodiments, the nanobubbles comprise an amphiphilic ABC triblock copolymer, wherein block A comprises a hydrophilic polymer, block B comprises a crosslinking polymer, and block C comprises a hydrophobic copolymer comprising (i) methyl methacrylate (MMA) and (ii) a fluorinated monomer, wherein the fluorinated monomer is present in the hydrophobic copolymer of block C at 25 mole percent or less. Related treatment and diagnostic methods, as well as materials relating to the nanobubbles are provided herein. Methods of making a random copolymer are furthermore provided herein.
    Type: Grant
    Filed: October 10, 2012
    Date of Patent: August 16, 2016
    Assignee: THE REGENTS OF THE UNIVERSITY OF MICHIGAN
    Inventors: Mohamed El-Sayed, Yasemin Yuksel Durmaz
  • Patent number: 9408953
    Abstract: A biodegradable in vivo supporting device is disclosed. The in vivo supporting device comprises a biodegradable metal scaffold and a biodegradable polymer coating covering at least a portion of the biodegradable metal scaffold, wherein the biodegradable polymer coating has a degradation rate that is faster than the degradation rate of the biodegradable metal scaffold.
    Type: Grant
    Filed: February 4, 2016
    Date of Patent: August 9, 2016
    Assignee: Q3 MEDICAL DEVICES LIMITED
    Inventor: Eric K. Mangiardi
  • Patent number: 9408799
    Abstract: An aerosol antiperspirant composition comprising: at least one active antiperspirant ingredient, a bis-vinyl dimethicone/dimethicone copolymer, a silicone solvent, at least one fatty acid ester and at least one propellant.
    Type: Grant
    Filed: April 19, 2013
    Date of Patent: August 9, 2016
    Assignee: Colgate-Palmolvie Company
    Inventor: Robert Gruytch