Patents Examined by Audrea B Coniglio
  • Patent number: 10471131
    Abstract: The invention provides topical compositions and methods for using the compositions. The compositions can be used for the treatment of fibrotic or connective tissue disorders involving scarring, sub-dermal plaque accumulations, or fibrosis of muscle tissue. The disorders can be painlessly treated by the topical application of a composition described herein. One or more calcium channel blocker agents can serve as an active ingredient of the compositions, optionally in combination with, for example, one or more of emu oil and superoxide dismutase. The composition can further include pharmaceutically acceptable carriers that can facilitate the non-invasive transdermal delivery of the active(s) to subdermal sites.
    Type: Grant
    Filed: December 28, 2015
    Date of Patent: November 12, 2019
    Assignee: Hybrid Medical, LLC
    Inventors: Jeff Twidwell, Joel Buckley, Harold Hoium
  • Patent number: 10456410
    Abstract: A dressing for wound healing is provided, wherein the dressing includes a hydrogen sulfide (H2S) donor compound. The dressing facilitates the delivery of H2S to a wound site in a controlled manner, which results in an improved wound healing process by stimulating angiogenesis and anti-inflammatory action. In some embodiments, the wound dressing can include an electrospun nanofiber dressing, a sponge dressing, or a hydrogel dressing.
    Type: Grant
    Filed: August 1, 2017
    Date of Patent: October 29, 2019
    Assignee: University of South Carolina
    Inventor: Qian Wang
  • Patent number: 10441639
    Abstract: Pharmaceutical compositions comprising plasminogen or a biologically active variant thereof are disclosed. In an embodiment, the composition comprises a tonicity modifier, a bulking agent, and a stabilizing agent and has a pH of about 3.0 to about 10.0. In another embodiment, the composition contains an amount of particles in suspension equal to or greater than 10 ?m which is lower than 6000 particles per 100 ml, and preferably lower than 2000 particles per 100 ml. Uses of these compositions as a medicament is contemplated. Various therapeutic uses of these pharmaceutical compositions is also contemplated.
    Type: Grant
    Filed: December 18, 2015
    Date of Patent: October 15, 2019
    Assignee: PROMETIC BIOTHERAPEUTICS, INC.
    Inventors: Davida Blackman, Stacy Plum, William Garzon-Rodriguez, Martin Robitaille, Betty Yu
  • Patent number: 10441518
    Abstract: The disclosure relates to compositions for treating keratinous substrates, such as the hair, comprising 3-butoxypropylamine and at least one carboxylic acid, as well as systems and methods for treating keratinous substrates with the compositions.
    Type: Grant
    Filed: November 24, 2016
    Date of Patent: October 15, 2019
    Assignee: L'OREAL
    Inventors: Kimberly Christine Dreher, Gérard Provot, Dariusz Danielski, Fabien Pascal Boulineau, Caroline Rahmouna Françoise Goget, Anthony Potin, Allison Chin, Michael Degeorge, Mara Applebaum, Mary Abraam Soliman, Ashley Ann Figatner, Megan Pauker, Emmanuel Appiah-Amponsah
  • Patent number: 10433546
    Abstract: A solid glutaraldehyde composition is provided having an increased glass transition temperature. The glutaraldehyde can be used in a method of treating a wellbore or a subterranean formation, by introducing the composition to a wellbore or to an injection line within a wellbore in an amount effective to reduce biodegradation of crude oil, reduce corrosion of metal surfaces from sulfur-reducing bacteria, or to reduce the introduction of bacteria into the formation, reduce microbial contamination of a fluid introduced into the wellbore, or reduce microbial contamination of a pipeline.
    Type: Grant
    Filed: March 6, 2017
    Date of Patent: October 8, 2019
    Assignee: Ecolab USA Inc.
    Inventors: David Daniel McSherry, Benjamin Crew, Justin Scott Valenstein
  • Patent number: 10420726
    Abstract: Orally administrable pharmaceutical compositions, methods of administration, and methods of making the same are provided. The pharmaceutical compositions provide abuse deterrent properties.
    Type: Grant
    Filed: March 18, 2014
    Date of Patent: September 24, 2019
    Assignee: INSPIRION DELIVERY SCIENCES, LLC
    Inventors: Manish S. Shah, Ray J. Difalco, Stefan Aigner
  • Patent number: 10413514
    Abstract: Disclosed is a controlled-release solid preparation, which consists of an internal core and a coating layer, wherein part of the surface of the internal core is not covered with the coating, and is exposed to the surface of the solid preparation. Since the medicament just releases at the exposed part, the aim of controlled release can be achieved by controlling this exposed surface area.
    Type: Grant
    Filed: April 8, 2015
    Date of Patent: September 17, 2019
    Assignee: OVERSEAS PHARMACEUTICALS, LTD.
    Inventor: Xiaoguang Wen
  • Patent number: 10412966
    Abstract: Disclosed are novel active substance combinations comprising specific heterocyclic trifluorobutenyls and previously known fungicidal agents. Said active substance combinations have a very good synergistic fungicidal, nematicidal, insecticidal, and/or acaricidal effect.
    Type: Grant
    Filed: March 30, 2017
    Date of Patent: September 17, 2019
    Assignee: ADAMA MAKHTESHIM LTD.
    Inventors: Wolfram Andersch, Ulrike Wachendorff-Neumann, Anton Kraus
  • Patent number: 10414658
    Abstract: Disclosed is a composition of matter comprising a biologically active substance bound to a graphene-coated dielectric-core particle, and methods for making and using the same.
    Type: Grant
    Filed: February 15, 2017
    Date of Patent: September 17, 2019
    Assignee: Millman Systems LLC
    Inventor: Stephen Jeffery Gorton
  • Patent number: 10406192
    Abstract: The present invention is a diffusional patch having an oil mixture (20) providing mechanical treatment support by reducing the edema in volume and in mass by throwing out the liquid inside by means of diffusion effect after entering into the region with edema by means of the diffusion effect and placed into a porous sheath (10) in microfiber structure, in order to be used in treatment of region with edema which may occur in sports injuries and/or disc hernia (50); characterized in that said oil mixture (20), of which the ingredient proportions in weight are given, comprises the below mentioned ingredients and does not comprise water: Ingredient Amount (%) Dextrin Palmitate Derivatives 1-10 Paraffin 1-30 Oleum nigellae sativae (black cumin oil) 0-20 Oleum origani (carvacrol) 0-20 Oleum lauri expressum (laurel oil) 0-30 Oleum chamomillae (chamomile oil) 0-30 Balsamum meccae (balsam oil) 0-30 Styrax liguidus (sweetgum) 0-30 Oleum limonis (lemon oil) 0-10 Oleum rosmarini (rosemary oil) 0-10 Olive oil 0-30 Oleum v
    Type: Grant
    Filed: June 5, 2014
    Date of Patent: September 10, 2019
    Assignee: METUAS MEDIKAL SAGLIK HIZMETLERI DANISMANLIK IHRACAT ITHALAT A.S. SIRKETI
    Inventors: Mehmet Sorar, Tuba Çalik
  • Patent number: 10398642
    Abstract: The present disclosure provides a sterilized chlorhexidine product for topical disinfection. The product includes a sterilized chlorhexidine gluconate composition, an applicator for facilitating application of the sterilized chlorhexidine composition, and a receptacle containing the sterilized chlorhexidine gluconate composition to provide the sterilized chlorhexidine gluconate composition to impregnate the applicator when the receptacle is compromised. The sterilized chlorhexidine gluconate composition includes chlorhexidine gluconate and alcohol.
    Type: Grant
    Filed: December 21, 2018
    Date of Patent: September 3, 2019
    Assignee: Sage Products, LLC
    Inventors: Jennifer M. Allen, Christopher J. Grannis, Syed M. Hasan, Timothy P. Manthei, Niles R. Manwill
  • Patent number: 10398727
    Abstract: The present invention relates to methods for the treatment or prevention of asbestos related diseases, in particular mesothelioma and asbestosis, and further to methods for the treatment or prevention of asbestos-induced DNA damage. These methods involve administration to a subject in need thereof compositions comprising zeolite or zeolite-like materials such as clinoptilolite.
    Type: Grant
    Filed: November 24, 2015
    Date of Patent: September 3, 2019
    Assignee: University of Technology, Sydney
    Inventors: Anthony George, Jason Ravasini
  • Patent number: 10376526
    Abstract: The present invention relates to a stable fixed dose aqueous pharmaceutical composition (e.g., contained in a container) for nasal administration to a human, comprising mometasone or its salt, olopatadine or its salt. The composition may further include a hydrocolloid. The invention also relates to a process for preparing the pharmaceutical composition, and the use of the pharmaceutical composition in the treatment of rhinitis in a subject.
    Type: Grant
    Filed: September 13, 2017
    Date of Patent: August 13, 2019
    Assignee: GLENMARK SPECIALTY S.A.
    Inventors: Ulhas R. Dhuppad, Ashok Katkurwar, Yashwant Gupta, Rajesh Ankam, Chandrakant Dhatrak
  • Patent number: 10363218
    Abstract: A method of preparing probiotic nanoparticles can include dissolving formulated probiotics in methanol, spraying the methanol solution into boiling water under ultrasonic conditions to provide a sonicated solution, and stirring the sonicated solution to obtain probiotic nanoparticles. The probiotic nanoparticles may be cluster or rod-shaped. The probiotic nanoparticles may be administered to a subject to reduce oxidative stress or to treat diseases associated with oxidative stress.
    Type: Grant
    Filed: January 3, 2019
    Date of Patent: July 30, 2019
    Assignee: King Saud University
    Inventors: Promy Virk, Manal Ahmed Gasmelseed Awad, Amnah El-Enazy, Awatif Ahmed Hendi, Mai Abdelrahman Elobeid Wagealla, Rabia Qindeel
  • Patent number: 10362784
    Abstract: Dry mixtures and liquid formulations are provided that comprise metal oxide and/or metal hydroxide nanocrystalline particles. The dry mixtures are advantageously formulated with select surfactants to be readily solubilized and stable in liquid carriers. Additional select components are provided in preferred combinations that are capable of achieving improved biocidal and chemical agent efficacy. Notably, the inventive formulations provided herein allow for easier delivery of the formulations and increased shelf stability.
    Type: Grant
    Filed: June 30, 2017
    Date of Patent: July 30, 2019
    Assignee: Timilon Technology Acquisitions LLC
    Inventors: Bill Sanford, Brandon Walker, Paul S. Malchesky, Kyle Knappenberger, Calvin Jeffrey Kissick, Eric Steward
  • Patent number: 10342748
    Abstract: The invention relates to stable dispersions, containing (a) 50 to 80% by weight of perfume oils, (b) 10 to 30% by weight of encapsulated fragrances, (c) 0.01 to 0.1% by weight of non-ionic polymers of the type of hydrophobically modified hydroxylalkyl guar compounds, with the proviso that the constituents together with water and optionally other typical auxiliary agents and additives add up to 100% by weight.
    Type: Grant
    Filed: February 14, 2016
    Date of Patent: July 9, 2019
    Assignee: Symrise AG
    Inventors: Jörg Dröge, Jörn Wiedemann
  • Patent number: 10307351
    Abstract: Substrates having formulations disposed thereon, wherein the formulations have improved transfer rates from the substrate to skin, are disclosed herein. More particularly, the formulations can be applied to nonwoven, particularly elastomeric substrates, as well as tissue paper, and can be easily and efficiently transferred from the substrate to the skin of a user upon intimate contact thereto. Laminated articles using one or more of the substrates having the formulations disposed thereon are further disclosed.
    Type: Grant
    Filed: March 15, 2018
    Date of Patent: June 4, 2019
    Assignee: Kimberly-Clark Worldwide, Inc.
    Inventors: Stacy Averic Mundschau, Scott W. Wenzel, Lisa Ann Flugge-Berendes, Jonathan Kyle Arendt, Kroy Donald Johnson, Bernard J. Minerath
  • Patent number: 10300169
    Abstract: Hydrogels comprising a macromolecular matrix and water may be used to augment soft tissue of a human being, promote or support cell or tissue viability or proliferation, create space in tissue, and for other purposes. A macromolecular matrix may comprise a hyaluronic acid component crosslinked to a silk fibroin component.
    Type: Grant
    Filed: August 24, 2017
    Date of Patent: May 28, 2019
    Assignee: Allergan, Inc.
    Inventors: Xiaojie Yu, Darin J. Messina, Elizabeta Pavlovic, Cunqi Cui, Kate M. Smither
  • Patent number: 10300041
    Abstract: Aqueous suspensions for oral administration are disclosed that include simvastatin having a d90 of simvastatin particles of less than about 100 ?m as the active agent. The aqueous suspension also includes simvastatin as about 20 mg to about 80 mg per 5 ml of the aqueous suspension, a suspending agent as about 20 mg to about 50 mg of the aqueous suspension, a wetting agent, an antimicrobial preservative, an antifoaming agent, water, and a buffering system providing the aqueous suspension with a pH of about 6.4 to about 7. Methods of making such a suspension and methods of treatments in orally administering the same are also disclosed.
    Type: Grant
    Filed: February 3, 2017
    Date of Patent: May 28, 2019
    Assignee: Rosemont Pharmaceuticals LTD
    Inventor: Phillip Driver
  • Patent number: 10278902
    Abstract: A method of cosmetically modifying the appearance of the outline of the eye, the method including the step consisting in applying at least one patch on the movable upper eyelid, the application face of the patch having a predefined non-plane shape with multi-directional curvature, or at least one patch made of a material suitable for responding to stress by deforming in non-elastic manner as to take up multi-directional curvature on the eyelid and conserve the curvature when the stress ceases.
    Type: Grant
    Filed: January 17, 2011
    Date of Patent: May 7, 2019
    Assignee: L'OREAL
    Inventors: Nathalie Jager Lezer, Henri Samain, Vincent De Laforcade