Patents Examined by Benjamin R. Padgett
  • Patent number: 4473402
    Abstract: New cobalt base alloys containing chromium and carbon are disclosed. The alloys are subjected to rapid solidification processing (RSP) technique which produces cooling rates between 10.sup.5 to 10.sup.7 .degree. C./sec. The as-quenched ribbon, powder etc. consists predominantly of amorphous phase. The amorphous phase is subjected to suitable heat treatments so as to produce a transformation to a microcrystalline alloy which includes carbides; this heat treated alloy exhibits superior mechanical properties for numerous industrial applications.
    Type: Grant
    Filed: April 11, 1983
    Date of Patent: September 25, 1984
    Inventors: Ranjan Ray, Viswanathan Panchanathan
  • Patent number: 4473491
    Abstract: Alkanolamine salts of amide acids having the formula: ##STR1## in which the circle represents a single nucleous aromatic ring or a monocyclic or bicyclic aliphatic ring system in each case with 5 or 6 carbon atoms per ring in which R.sup.1 represents an isoalkyl radical with the longest chain of 6 to 8 carbon atoms and a total of 8 to 12 carbon atoms; R.sup.2 represents a radical alkylene-X wherein the alkylene chain is a branched or straight chain and contains 1 to 4 carbon atoms; X represents OR.sup.3, O(C.sub.2 H.sub.4 O).sub.n -R.sup.3, O(C.sub.3 H.sub.6 O).sub.n -R.sup.3, NR.sup.3 R.sup.3, CN, CONH.sub.2, and COOR.sup.3 ; R.sup.3 represents hydrogen or C.sub.1 to C.sub.4 alkyl; n is an integer of 1 to 4; and wherein the carboxyl and carbonamide groups in said formula are bonded to non-olefinic carbon atoms and arranged in adjacent positions. The use of these salts as corrosion inhibitors in aqueous systems is also disclosed.
    Type: Grant
    Filed: June 11, 1982
    Date of Patent: September 25, 1984
    Assignee: BASF Aktiengesellschaft
    Inventors: Walter Trautmann, Elmar Getto
  • Patent number: 4472286
    Abstract: The instant invention relates to the use of ion-pair complexes derived from anionic perfluoroalkyl sulfonates, carboxylates, phosphates and phosphonates and cationic perfluoroalkyl surfactants. Such complexes are capable of reducing the surface tension of aqueous solutions dramatically even at extremely low concentrations, and are useful as wetting, spreading and leveling agents and are especially preferred as components in so-called aqueous film forming foam compositions for fighting polar and non-polar solvent and fuel fires.
    Type: Grant
    Filed: October 31, 1983
    Date of Patent: September 18, 1984
    Assignee: Ciba-Geigy Corporation
    Inventor: Robert A. Falk
  • Patent number: 4471057
    Abstract: Colorectal carcinoma is detected by testing body fluids for the colorectal carcinoma monosialoganglioside identified by monoclonal antibodies produced by fused cell hybrid ATCC HB 8059.
    Type: Grant
    Filed: June 30, 1981
    Date of Patent: September 11, 1984
    Assignee: The Wistar Institute
    Inventors: Hilary Koprowski, Zenon Steplewski, Meenhard Herlyn
  • Patent number: 4471058
    Abstract: A method for the detection and/or determination of an antigen having at least two separate antibody combining sites or antigenic determinants (i.e. a polyvalent antigen) using at least two different monoclonal antibodies which bind to the separate sites is described. In particular the method utilizes Protein A with a carrier to immobilize a first monoclonal antibody which in turn, can bind to one antigenic determinant on the antigen. The second antibody with a label is provided in a solution and binds to the second antigenic determinant on the antigen. A test kit is described for practicing the method. Novel anti-PGH synthase and anti-PGI.sub.2 synthase antibodies and hybridoma cells producing such antibodies are described.
    Type: Grant
    Filed: July 26, 1982
    Date of Patent: September 11, 1984
    Assignee: Board of Trustees operating Michigan State University
    Inventors: William L. Smith, David L. DeWitt
  • Patent number: 4470953
    Abstract: The object of the invention is a process of manufacturing a sintered compact of sinterable pulverulent material, in which the powder is moulded against a moulding surface and sintered in contact with the moulding surface and in which the pores in at least local areas of the compact are sealed by infiltration with an infiltration material which during a stage of the infiltration process is in liquid form and which by temperature decrease is caused to solidify in the pores, and the characteristic features of the invention are that the moulding takes place on the moulding surface in such a way that the moulding surface is covered with relatively fine-grained sinterable powder which by its own adhesion or by adhesion intensified by additives is caused to form an at least temporarily retained fine powder layer (3) on the moulding surface, and that at least one layer (5) of sinterable coarse powder is applied to the fine powder layer, and that both layers are sintered and infiltration is effected such that the infi
    Type: Grant
    Filed: February 5, 1982
    Date of Patent: September 11, 1984
    Assignee: Uddeholms Aktiebolag
    Inventor: Lars M. Bruce
  • Patent number: 4469622
    Abstract: Disclosed is an imidazole-4(5)-dithiocarboxylic acid compound represented by the following general formula: ##STR1## wherein R.sub.2 stands for a hydrogen atom or a monovalent hydrocarbon group having up to 20 carbons, R.sub.4 stands for a hydrogen atom or an alkyl group having up to 4 carbon atoms, and X stands for a hydrogen atom or an alkali metal atom.This compound has an excellent rust preventive action to silver. This compound is prepared according to a process which comprises reacting an imidazole compound represented by the following general formula: ##STR2## wherein R.sub.2 and R.sub.4 are as defined above, with carbon disulfides and an alkali metal hydroxide in the presence of a solvent, and if necessary, acidifying the obtained imidazole compound.
    Type: Grant
    Filed: January 24, 1983
    Date of Patent: September 4, 1984
    Assignee: Shikoku Chemicals Corporation
    Inventors: Natsuo Sawa, Tokuichi Saeki
  • Patent number: 4468437
    Abstract: Methods for improving microstructures of line-of-sight deposited films are described. Columnar growth defects ordinarily produced by geometrical shadowing during deposition of such films are eliminated without resorting to post-deposition thermal or mechanical treatments. The native, as-deposited coating qualities, including homogeneity, fine grain size, and high coating-to-substrate adherence, can thus be retained. The preferred method includes the steps of emitting material from a source toward a substrate to deposit a coating non-uniformly on the substrate surface, removing a portion of the coating uniformly over the surface, again depositing material onto the surface, but from a different direction, and repeating the foregoing steps. The quality of line-of-sight deposited films such as those produced by sputtering, progressively deteriorates as the angle of incidence between the flux and the surface becomes increasingly acute.
    Type: Grant
    Filed: February 22, 1982
    Date of Patent: August 28, 1984
    Assignee: Battelle Memorial Institute
    Inventors: James W. Patten, Ronald W. Moss, Edwin D. McClanahan
  • Patent number: 4467811
    Abstract: A method of measuring lactic acid or lactate and derivatives thereof in liquids which is extremely versatile and is suitable for use in a number of areas such as the rapid measurement of lactic acid in whole blood, the ratio of lactic acid to pyruvic acid in whole blood, in-vivo measurement of lactic acid and the study of living lactic acid-producing cells. The acid or lactate is measured by reacting the lactic acid with lactic oxidase to produce pyruvate and H.sub.2 O.sub.2. The H.sub.2 O.sub.2 is then measured polarographically. The current produced is directly proportional to the lactate level. Preferably, the lactic oxidase is trapped between two semi-permeable membranes. One membrane is placed in contact with an electrolyte at the tip of an electrode and the second membrane contacts the liquid being tested.
    Type: Grant
    Filed: February 8, 1982
    Date of Patent: August 28, 1984
    Assignee: Children's Hospital Medical Center
    Inventor: Leland C. Clark, Jr.
  • Patent number: 4467814
    Abstract: A novel method for determining when cows are in estrus is disclosed comprising the step of monitoring the vaginal secretions of a cow to determine an increase in the amount of an indicator compound in said secretions. A significant increase in the amount of the indicator compound, concentrations above about 0.1 micrograms per gram of collected secretion, is indicative of estrus. The preferred indicator alcohols have ethyl ester indices of 8.1 to 8.9. In particular these alcohols are methyl-1-heptanols, such as 6-methyl-1-heptanol, or are methyl hydroxy heptenes, such as 2-methyl-7 hyroxy-.DELTA.-3-4 heptene. Alternatively, a cow may be determined to be in estrus simply to ascertaining that the concentration of methyl-1-heptanol is at least 0.1 microgram per gram of collected vaginal secretion.
    Type: Grant
    Filed: March 19, 1982
    Date of Patent: August 28, 1984
    Assignee: Monell Chemical Senses Center
    Inventor: George Preti
  • Patent number: 4465621
    Abstract: An immersion oil formulation for use in microscopy and related optical fields consists of a blend of a dialkyl phthalate, a butyl benzyl phthalate and chlorinated paraffin. The compounds, when blended, possess a desired optical property including a refractive index of 1.518 or thereabouts and an extremely low fluorescence enabling the immersion oil to be utilized in the field of fluorescence microscopy. The resultant blend also possesses a low toxicity and therefore eliminates all the disadvantages of prior art immersion oils which contain PCBs or which exhibit undesirably high auto fluorescence.
    Type: Grant
    Filed: July 1, 1983
    Date of Patent: August 14, 1984
    Assignee: R. P. Cargille Laboratories, Inc.
    Inventor: Robert Sacher
  • Patent number: 4465488
    Abstract: A collapsible medical agent container (10) is disclosed having walls (34, 36, 38) defining a plurality of chambers (12, 14) for containing selected quantities of one or more medical fluids or a dry or encapsulated drug or other reagent in separate sealed condition. Opening means which communicates between adjacent chambers (12, 14) for passage of fluid from one chamber to another, is normally closed by frangible closure (18) which maintains the chambers (12, 14) in separate hermetically sealed condition until flow between the chambers (12, 14) is needed. The frangible closure (18) has an elongated relatively rigid portion (20) which extends into one of the chambers and is disposed within a protective retentive tube (24), and a relatively weakened portion (22) adjacent the opening means.
    Type: Grant
    Filed: March 23, 1981
    Date of Patent: August 14, 1984
    Assignee: Baxter Travenol Laboratories, Inc.
    Inventors: Frank M. Richmond, Kenneth W. Larson, Robert A. Miller
  • Patent number: 4465480
    Abstract: Devices such as blood transfusion tubes, which can be contacted with human blood at reduced risk of blood clotting, made of a segmented polyether polyurethane urea obtained by chain extending an isocyanate-terminated prepolymer with a diamine having a branch at at least one .alpha.-carbon atom, such as 1,2-propylene diamine or 1,4-cyclohexylene diamine.
    Type: Grant
    Filed: December 21, 1981
    Date of Patent: August 14, 1984
    Assignee: Toyo Boseki Kabushiki Kaisha
    Inventors: Masakazu Tanaka, Ken Murayama
  • Patent number: 4465515
    Abstract: To provide piston rings which are ductile, can be heavily thermally loaded, and are not attacked by corrosive residues occurring upon combustion of residual oil or other sulfur-containing heavy Diesel oils, a powder mixture is sintered in an isostatic hot-pressure sintering process in which a hard metal and a soft filler material are combined; in accordance with one embodiment, the base is a hard metal using nickel or cobalt-based alloys present in 40-80% by weight, the remainder filler which, for example, is unrefined or galvanically coated graphite; in a second embodiment, the base is a soft material such as a high-copper content bronze, and the filler is a nickel or cobalt-based alloy, with the base metal being present in 60-80%, the filler being the remainder (all percentages by weight).
    Type: Grant
    Filed: July 24, 1981
    Date of Patent: August 14, 1984
    Assignee: M.A.N. Maschinenfabrik Augsburg-Nurnsberg Aktiengesellschaft
    Inventor: Frank Mundorff
  • Patent number: 4465776
    Abstract: A continuous hybridoma cell line which secretes recoverable quantities of monoclonal antibodies having specificity against Vitamin B.sub.6, which antibodies are useful in a method for detecting the presence of vitamin B.sub.6 in an animal sample.
    Type: Grant
    Filed: September 27, 1982
    Date of Patent: August 14, 1984
    Assignee: Research Corporation
    Inventors: John A. Cidlowski, Dace Viceps-Madore
  • Patent number: 4465775
    Abstract: Vitamin B.sub.12 in liquid samples, such as human serum or human plasma, is assayed by a competitive binding technique using intrinsic factor and certain labelled vitamin B.sub.12 derivatives. The labelled derivatives are formed from the (d)-monocarboxylic acid isomer of vitamin B.sub.12, which isomer is free from other monocarboxylic acid isomers (and derivatives thereof) of vitamin B.sub.12, by binding to the (d)-isomer, via the carboxylic group, a compound which is itself a label (e.g. an enzyme) or which comprises a label (e.g. a fluorophore), or to which a label is attached (e.g. a histidine ester to which .sup.125 I is attached). The labelled derivatives of the (d)-monocarboxylic acid of vitamin B.sub.12, free from other isomeric monocarboxylic acids and derivatives, are novel and constitute one aspect of the invention.
    Type: Grant
    Filed: May 24, 1982
    Date of Patent: August 14, 1984
    Assignee: Technicon Instruments Corporation
    Inventor: Thomas M. Houts
  • Patent number: 4462880
    Abstract: Described is a process for imparting an "air dried cloth" aroma to cloth, synthetic or natural, previously dried using a clothes drier, comprising the step of contacting the cloth prior to drying with an aroma augmenting or enhancing quantity of either (i) a mixture consisting essentially of:(a) from about 0.5 up to about 5% by weight of said composition of n-hexanal;(b) from about 2 up to about 12% by weight of said composition of n-heptanal;(c) from about 5 up to about 15% by weight of said composition of n-octanal;(d) from about 40 up to about 70% by weight of said composition of n-nonanal;(e) from about 10 up to about 30% by weight of said composition of n-decanal;(f) from about 0.5 up to about 5% by weight of said composition of n-undecanal;(g) from about 0.5 up to about 5% by weight of said composition of n-dodecanal;(h) from about 0.
    Type: Grant
    Filed: September 26, 1983
    Date of Patent: July 31, 1984
    Assignee: International Flavors & Fragrances Inc.
    Inventors: Ira D. Hill, Robert W. Trenkle, Braja D. Mookherjee, Robin K. Wolff
  • Patent number: 4462980
    Abstract: Novel plasmin compositions, conditioned for labelling with technetium-99m by containing a pertechnetate reducing reagent, and plasmin admixed with a plasmin stabilizing agent.The novel compositions are particularly suited for the preparation of technetium-99m labelled plasmin used as a scintigraphic scanning agent for the detection of venous thrombosis.
    Type: Grant
    Filed: January 4, 1982
    Date of Patent: July 31, 1984
    Assignee: Novo Industri A/S
    Inventors: Allan Diedrichsen, Marie Johannessen, Peter Tang
  • Patent number: 4461721
    Abstract: A wood preservative based on an aqueous mixture of boric acid and a water-soluble organic amine, which mixture additionally contains sodium polyborate or a mixture of boric acid and borax.
    Type: Grant
    Filed: April 12, 1982
    Date of Patent: July 24, 1984
    Assignee: BASF Aktiengesellschaft
    Inventors: Reimer Goettsche, Hans-Norbert Marx
  • Patent number: 4461720
    Abstract: A composition for treating wood to impart fire retardance prepared by converting dicyandiamide to an aqueous guanyl urea solution, methylolating the guanyl urea and introducing phosphoric acid to produce a phosphate salt of the methylolated guanyl urea.
    Type: Grant
    Filed: May 24, 1982
    Date of Patent: July 24, 1984
    Assignee: Hoover Treated Wood Products, Inc.
    Inventors: Andre G. Loyvet, Dennis J. Morgan