Patents Examined by Blaine Lankford, Jr.
  • Patent number: 9624473
    Abstract: Provided herein is a three-dimensional scaffold composition comprising randomly oriented fibers, wherein the fibers comprise a polyethylene glycol-polylactic acid block copolymer (PEG-PLA) and a poly(lactic-co-glycolic acid) (PLGA). Also provided are methods for using the three-dimensional scaffolds described herein.
    Type: Grant
    Filed: February 25, 2013
    Date of Patent: April 18, 2017
    Inventors: Subhra Mohapatra, Shyam S. Mohapatra, Yvonne Kathleen Davis, Chunyan Wang
  • Patent number: 9347045
    Abstract: Methods and compositions are provided for the differentiation and characterization of mammalian fibroblast from mesenchymal stem cells. The methods of the invention provide a means to obtain mesenchymal stem cell-derived fibroblast populations, e.g., seeded on a scaffold, which may be used in wound healing.
    Type: Grant
    Filed: December 21, 2012
    Date of Patent: May 24, 2016
    Assignee: ESCAPE THERAPEUTICS, INC.
    Inventor: Basil M. Hantash
  • Patent number: 9168274
    Abstract: The Present Invention aims to diminish the effects of alcohol consumption by breaking down the “stacked” excess alcohol in the digestive track through its probiotic element which effectively “eats” away at the alcohol before the liver has to process it. It comprises a personal dose of Acetobacter aceti, which is a benign microorganism that is ubiquitous in the environment, existing in alcoholic ecological niches such as flowers, fruits, honey bees, as well as in water and soil.
    Type: Grant
    Filed: October 16, 2013
    Date of Patent: October 27, 2015
    Inventor: Jonathan Gropper
  • Patent number: 9163210
    Abstract: The present disclosure relates to production of double-coated lactic acid bacteria using peptides and polysaccharide. Double-coated lactic acid bacteria show improved heat-resistance, acid-resistance, bile-resistance, storage stability and excellent survival rate when reaching intestine.
    Type: Grant
    Filed: February 12, 2015
    Date of Patent: October 20, 2015
    Inventor: Myung-Jun Chung
  • Patent number: 9155755
    Abstract: Beta glucan and fulvic acid can be combined in a dietary supplement as a partial substitute or complete replacement for blue green algae and/or brown seaweed and its derivatives. Beta glucans are widely available as derivatives of Brewer's yeast and fulvic acid is widely available as well. These supplements are not subject to the vagaries of weather-influence growing seasons as is the case with blue green algae and brown seaweed. When combined, beta glucan and fulvic acid can provide a less costly dietary supplement than blue green algae and brown seaweed and its derivatives such as fucoidan.
    Type: Grant
    Filed: March 12, 2014
    Date of Patent: October 13, 2015
    Inventor: John V. Cappello
  • Patent number: 9134299
    Abstract: The present invention relates to a pharmaceutical composition comprising of preparations of human embryonic stem (hES) cells and their derivatives and methods for their transplantation into the human body, wherein transplantation results in the clinical reversal of symptoms, cure, stabilization or arrest of degeneration of a wide variety of presently incurable and terminal medical conditions, diseases and disorders. The invention further relates to novel processes of preparing novel stem cell lines which are free of animal products, feeder cells, growth factors, leukaemia inhibitory factor, supplementary mineral combinations, amino acid supplements, vitamin supplements, fibroblast growth factor, membrane associated steel factor, soluble steel factor and conditioned media. This invention further relates to the isolation, culture, maintenance, expansion, differentiation, storage, and preservation of such stem cells.
    Type: Grant
    Filed: October 31, 2013
    Date of Patent: September 15, 2015
    Inventor: Geeta Shroff
  • Patent number: 8911986
    Abstract: Temporary active coatings that are stabilized against inactivation by weathering are provided including a base associated with a chemically modified enzyme, and, optionally a first polyoxyethylene present in the base and independent of the enzyme. The coatings are optionally overlayered onto a substrate to form an active coating facilitating the removal of organic stains or organic material from food, insects, or the environment.
    Type: Grant
    Filed: April 29, 2011
    Date of Patent: December 16, 2014
    Assignees: Toyota Motor Engineering & Manufacturing North America, Inc., Toyota Motor Corporation
    Inventors: Hongfei Jia, Songtao Wu, Masahiko Ishii, Minjuan Zhang
  • Patent number: 8883499
    Abstract: Systems and methods are described that are used to separate cells from a wide variety of tissues. In particular, automated systems and methods are described that separate regenerative cells, e.g., stem and/or progenitor cells, from adipose tissue. The systems and methods described herein provide rapid and reliable methods of separating and concentrating regenerative cells suitable for re-infusion into a subject.
    Type: Grant
    Filed: April 20, 2012
    Date of Patent: November 11, 2014
    Assignee: Cytori Therapeutics, Inc.
    Inventors: Marc H. Hedrick, John K. Fraser, Michael J. Schulzki, Bobby Byrnes, Grace Carlson, Ronda Elizabeth Schreiber, Isabella Wulur
  • Patent number: 8859226
    Abstract: There are provided a method of identifying the longum species alone, such as Bifidobacterium longum subsp. longum alone, and measuring the viable cell count thereof, amongst the bacterial cells to be tested which include a microorganism belonging to the genus Bifidobacterium by using a culture medium that contains L-arabinose as a sole sugar source; and also a culture medium which is useful as a selective medium for the above measurement method and which is also easy to prepare.
    Type: Grant
    Filed: March 25, 2011
    Date of Patent: October 14, 2014
    Assignee: Morinaga Milk Industry Co., Ltd.
    Inventors: Masamichi Muto, Fumiaki Abe, Tomoko Yaeshima
  • Patent number: 8679736
    Abstract: The methods of this invention involve preventing the formation of a complex between adenine and riboflavin by reducing the amount of adenine in a solution containing blood or blood components to be pathogen reduced.
    Type: Grant
    Filed: December 17, 2009
    Date of Patent: March 25, 2014
    Assignee: Terumo BCT Biotechnologies, LLC
    Inventors: Raymond P. Goodrich, Suzann K. Doane
  • Patent number: 8647620
    Abstract: The present invention relates to chimeric Factor VII polypeptides and methods of using the same.
    Type: Grant
    Filed: June 25, 2010
    Date of Patent: February 11, 2014
    Assignee: The University of North Carolina at Chapel Hill
    Inventors: Darrel W. Stafford, Dengmin Feng
  • Patent number: 8637002
    Abstract: Non-toxigenic strains of Aspergillus are useful biocontrol agents for preventing toxin contamination in agricultural commodities, especially those for human consumption such as peanuts and corn, for example.
    Type: Grant
    Filed: January 19, 2011
    Date of Patent: January 28, 2014
    Assignee: The United States of America, as represented by the Secretary of Agriculture
    Inventors: Joe W. Dorner, Bruce W. Horn
  • Patent number: 8623646
    Abstract: A method of enhancing the formation of extracellular matrix in culture. Cells in culture secrete most of the collagen into the media as unprocessed procollagen, i.e., the cells do not convert procollagen to collagen. In contrast, normal extracellular matrix deposition involves procollagen processing to collagen, fibril assembly and deposition into the cell layer to form a collagenous extracellular matrix. The addition of certain growth factors and the addition of a thin layer of a certain volume exclusion agent on top of the cells dramatically enhances the conversion of procollagen to collagen and will increase the amount of collagen and extracellular matrix associated with the cells. This invention advances bioengineering of connective tissues for medical applications that require an extensive and functional extracellular matrix with high tensile strength such as those in the cornea stroma, skin, tendons, ligaments, articular cartilage and the intervertebral disks.
    Type: Grant
    Filed: February 25, 2011
    Date of Patent: January 7, 2014
    Assignees: University of South Florida, Thomas Jefferson University
    Inventors: David E. Birk, John Hassell, Bradley Kane, La Tia Etheredge
  • Patent number: 8623613
    Abstract: Stains that are specific for calcium ion are used to assess and predict the effects of various treatments on the viability of cell types contained in a sample, wherein said stain detects endothelial cells that have massive calcium accumulation death.
    Type: Grant
    Filed: April 13, 2011
    Date of Patent: January 7, 2014
    Inventor: Larry M. Weisenthal
  • Patent number: 8614084
    Abstract: The present invention relates to a novel microbial strain, Alteromonas sp. SN2 (KCTC11700BP) having an activity for degrading polycyclic aromatic hydrocarbon (PAH), a bioremediation process of polycyclic aromatic hydrocarbon (PAH) contaminants, comprising contacting a microbial strain Alteromonas sp. with PAH, and a composition for purifying polycyclic aromatic hydrocarbon (PAH) contaminants, comprising a microbial strain Alteromonas sp. It is advantageous that the present invention may be suitably utilized in treatment or remediation of oil contaminants, particularly naphthalene soil contaminants without production of a secondary contaminant source. As the strain and bioremediation process of this invention could be industrially utilized through low-cost and environment-friendly process, the present technology also may be carried out much more economically and efficiently than conventional technologies such as thermal technology, solidification technology, and vapor extraction technology.
    Type: Grant
    Filed: May 28, 2010
    Date of Patent: December 24, 2013
    Assignee: Chung-Ang University Industry-Academy Cooperation Foundation
    Inventors: Che Ok Jeon, Hyun-Mi Jin, Se Hee Lee, Jeong Myeong Kim, Hyo Jung Lee
  • Patent number: 8597927
    Abstract: The invention provides methods, compositions, and kits for removal of biofilms from surfaces. The methods described herein comprise simultaneous or sequential application of a perhydrolase enzyme and a mixture of other enzymes, such as proteases, glucanases, esterases, mannanases, phospholipases, cellulases, and/or amylases, to a biofilm on a surface, to effect removal of the biofilm.
    Type: Grant
    Filed: December 16, 2008
    Date of Patent: December 3, 2013
    Assignee: Danisco US Inc.
    Inventors: Christopher C. Barnett, Manoj Kumar, Gregory M. Whited
  • Patent number: 8569040
    Abstract: The present invention pertains to compositions and methods for more efficiently and effectively growing microalgae suitable for biofuel production. In one aspect, the invention pertains to a composition comprising microalgae and a suitable growth medium. The suitable growth medium comprises a nutritionally acceptable nitrate salt, and a carbonate salt. The concentration of nutritionally acceptable nitrate salt is from about 75 to about 200 ?M while the concentration of carbonate salt is from about 1 to about 6 mM.
    Type: Grant
    Filed: July 23, 2012
    Date of Patent: October 29, 2013
    Assignees: Georgia Tech Research Corporation, Chevron U.S.A. Inc.
    Inventors: Nils Kroger, Stephen J. Miller, Nicole Poulsen
  • Patent number: 8557560
    Abstract: The present invention relates to a novel approach to prevent or treat mastitis both in humans and animals through the use of mammal milk-derived microorganisms obtained from healthy hosts of the homologous species; to those new probiotic microorganisms obtained from milk able to reduce infectious mastitis and the method of screening used for their obtaining; to the use of these probiotic bacteria for the prophylaxis or treatment against mastitis and other diseases; and finally, to compositions comprising these compounds.
    Type: Grant
    Filed: June 2, 2008
    Date of Patent: October 15, 2013
    Assignee: Puleva Biotech, S.A.
    Inventors: Rocio Martín Jiménez, Mónica Olivares Martín, Esther Antonia Jiménez Quintana, Maria Luisa Marín Martínez, Saleta Sierra Ávila, Antonio Maldonado Barragán, Virginia Martín Merino, Francesc Blanch Martell, Celina Torre Lloveras, Federico Lara Villoslada, Rebeca Arroyo Rodríguez, Julio Boza Puerta, Jesús Jiménez López, Leónides Fernández Álvarez, Odón Julían Sobrino Abuja, Jordi Xaus Pei, Juan Miguel Rodríguez Gómez, Susana Delgado Palacio
  • Patent number: 8557000
    Abstract: A process for converting lignocellulosic materials which are field residues such as cotton stalks and corn stover, process residues such as sugarcane bagasse and sweet sorghum bagasse, woody parts of energy crops such as switchgrass and miscanthus, forest residues or byproducts of the wood processing industries such as sawdust from sawmills to a liquid biofuel by a series of processing steps wherein the feed materials are hydrolysed in three stages and withdrawn as three product streams each consisting of solubilized fragments of one of the three major components of the feed materials and a set of concurrently operating processing steps wherein each of the three product streams is transformed through chemical or biochemical processes into products, such as pure lignin and ethanol, that have a high calorific value and process wherein these products with high calorific value are combined to form a liquid biofuel.
    Type: Grant
    Filed: February 4, 2009
    Date of Patent: October 15, 2013
    Assignee: Lignoil Technologies Private Limited
    Inventor: Pradyot A. Agaskar
  • Patent number: 8540985
    Abstract: The present invention concerns a method for modulating the enzymatic activity of an enzyme, wherein said enzyme interacts with BMP, said method comprising the step of administering or inducing Hsp70, or a functional fragment or variant thereof, in a form suitable for allowing interaction between BMP and Hsp70, or said functional fragment or variant thereof, and thereby modulating the enzymatic activity of an enzyme interacting with BMP.
    Type: Grant
    Filed: June 26, 2009
    Date of Patent: September 24, 2013
    Inventors: Thomas Kirkegaard Jensen, Marja Helena Jaattela