Patents Examined by Brian Gulledge
  • Cosmetic compositions
    Patent number: 11679067
    Abstract: A composition is provided. The composition is a water-in-oil emulsion comprising an aqueous phase and an oil phase. The aqueous phase comprises water, one or more humectants, one or more preservatives, one or more preservative boosters, one or more stabilizers and/or one or more pH adjusters. The oil phase comprises one or more solvents, one or more emulsifiers, one or more emollients and/or one or more aesthetic modifiers. Methods of preparing the composition and methods of improving the appearance of skin are also provided.
    Type: Grant
    Filed: June 29, 2021
    Date of Patent: June 20, 2023
    Assignee: L'Oreal
    Inventors: Catherine Chiou, Angelike Galdi, Kun Qian
  • Inhalable rapamycin formulation for treating age-related conditions
    Patent number: 11648199
    Abstract: The present invention relates to methods and compositions for anti-aging therapy and for the treatment and prophylaxis of age-related diseases and disorders in a human subject in need of such therapy or treatment, the methods comprising the pulmonary administration to the subject, preferably via inhalation, of composition comprising rapamycin, or a prodrug or derivative thereof.
    Type: Grant
    Filed: March 31, 2021
    Date of Patent: May 16, 2023
    Assignee: Al Therapeutics, Inc.
    Inventors: Thomas Armer, Lawrence S. Melvin, Jr., Jonathan M. Rothberg, Henri Lichenstein
  • Microcell systems for delivering hydrophilic active molecules
    Patent number: 11648215
    Abstract: A hydrophilic active molecule delivery system whereby active molecules can be released on demand and/or a variety of different active molecules can be delivered from the same system and/or different concentrations of active molecules can be delivered from the same system. The system may be used to deliver/release hydrophilic active molecules that are incompatible to each other.
    Type: Grant
    Filed: October 20, 2021
    Date of Patent: May 16, 2023
    Assignee: E INK CALIFORNIA, LLC
    Inventor: Lei Liu
  • Functional, segregated, charged telodendrimers and nanocarriers and methods of making and using same
    Patent number: 11649326
    Abstract: Provided are multiply functional charged telodendrimers. The telodendrimers can be used for protein encapsulation and delivery. The charged telodendrimers may have one or more crosslinking groups (e.g., boronic acid/catechol reversible crosslinking groups). The telodendrimers can aggregate to form nanoparticles. Cargo such as combinations of proteins and other materials may be sequestered in the core of the nanoparticles via non-covalent or covalent interactions with the telodendrimers. Such nanoparticles may be used in protein delivery applications.
    Type: Grant
    Filed: March 2, 2021
    Date of Patent: May 16, 2023
    Assignee: The Research Foundation for the State University of New York
    Inventors: Juntao Luo, Xu Wang, Changying Shi
  • Active ingredient including a black oat extract and a spiny restharrow extract and cosmetic uses, in particular anti-graying
    Patent number: 11648196
    Abstract: The invention relates to a cosmetic active ingredient comprising at least one extract of Avena strigosa and at least one extract of Ononis spinosa. The invention also relates to a composition including it, a method for obtaining it and the use of this cosmetic active ingredient, in particular for its anti-graying effect on the hair.
    Type: Grant
    Filed: February 24, 2021
    Date of Patent: May 16, 2023
    Assignee: SOCIETE INDUSTRIELLE LIMOUSINE D'APPLICATION BIOLOGIQUE
    Inventor: Jean Paufique
  • Dimethylsiloxane-alkylene oxide copolymers
    Patent number: 11642304
    Abstract: Copolymers are formed of monomers of poly(dimethylsiloxane) and poly(alkylene oxide) of the following formula: Ax-XCH2CH2—[ByCz]n—X-Ax. In the formula, each X independently represents a —CH2— group or an oxygen atom, A represents a polydimethylsiloxane derivative, B represents a polyethylene glycol unit, C represents a polypropylene glycol unit, x and n independently represent an integer from 1 to 150, and y and z independently represent an integer from 0 to 150. The copolymers can be used as emulsifiers in personal care compositions.
    Type: Grant
    Filed: July 25, 2019
    Date of Patent: May 9, 2023
    Assignee: CORNELIUS GROUP PLC
    Inventors: Thomas Guy Alabaster, Hannah Ruth Beasley-Suffolk, John Mark Bilney, Ella-Louise Ceraulo, John Ing Chuan Daly, Ian Stuart Pearce, Elizabeth Joan Smith, Robert Liam Smith, Christos Angeletakis, Yingfa Li
  • Skin external composition
    Patent number: 11642288
    Abstract: Provided is a liquid skin external composition which allows a poorly water-soluble component to be applied to a skin in a liquid state. An assembly of fiber for use in production of a liquid skin external composition, the assembly of fiber comprising (a) a polymer soluble in water and an alcohol or a ketone in a content of 50 mass % or more and 98 mass % or less with respect to the whole assembly of fiber and (b) a poorly water-soluble component in a content of 2 mass % or more and 40 mass % or less with respect to the whole assembly of fiber.
    Type: Grant
    Filed: February 5, 2021
    Date of Patent: May 9, 2023
    Assignee: KAO CORPORATION
    Inventors: Naomi Amari, Takuji Kume, Makoto Onoo, Takehiko Tojo, Rui Takahashi
  • Non-activated, amorphous, pH neutral, two-part bedside-ready clay delivery system that treats pathogen infections in humans and animals
    Patent number: 11638759
    Abstract: Clay delivery systems for providing antimicrobial compositions are provided. The delivery systems include a two-part active excipient system that delivers clay for various applications of use, including topical applications. The two-part delivery system can include a first part comprising suspending agent(s), poloxamer and optionally a gellant, and a second part that is simultaneously delivered therewith comprising one or more nonionic EO-PO block copolymers in a water-based system. The delivery systems beneficially provide clays in a stable system that also unexpectedly accelerate the release of the clay into the water system for activation and delivery that is enhanced by the poloxamers into the tissue or organ of the body in need of treatment thereof.
    Type: Grant
    Filed: August 13, 2020
    Date of Patent: May 2, 2023
    Inventor: Darlene E. McCord
  • Oil-based cosmetic preparation
    Patent number: 11638687
    Abstract: The present invention provides an oil-based cosmetic which is excellent in terms of a matte texture, while being highly stable. An oil-based cosmetic which is characterized by containing the following components (a)-(e). (a) a crosslinked organopolysiloxane (b) an amorphous anhydrous silicic acid (c) an oil-based gelling agent having a sugar skeleton (d) a liquid oil (e) a powder.
    Type: Grant
    Filed: July 19, 2019
    Date of Patent: May 2, 2023
    Assignee: Shiseido Company, Ltd.
    Inventor: Hiroshi Okamoto
  • Branched type hetero monodispersed polyethylene glycol, production method thereof, and conjugate thereof
    Patent number: 11613607
    Abstract: A branched type hetero monodispersed polyethylene glycol represented by formula (1) where X1, Y1, n, E, L1, L2 and L3 are as defined herein.
    Type: Grant
    Filed: October 6, 2017
    Date of Patent: March 28, 2023
    Assignees: TOKYO INSTITUTE OF TECHNOLOGY, NOF CORPORATION
    Inventors: Kazushi Kinbara, Tomoki Uruga, Tomoyuki Ohtake
  • Lyophilic colloids
    Patent number: 11612557
    Abstract: A non-Newtonian, lyophilic colloid comprised of (i) at least one anionic, non-sulfated glycosaminoglycan (ANSG) having a molecular weight greater than about 500 kDa and (ii) glycerin.
    Type: Grant
    Filed: July 14, 2022
    Date of Patent: March 28, 2023
    Assignee: Vantage Specialty Ingredients, Inc.
    Inventors: Juan R Mateu, Mackenzie Nunn, Oscar Ortiz-Gutierrez, Adam Perle
  • Sulfate free clear personal cleansing composition comprising low inorganic salt
    Patent number: 11607373
    Abstract: A clear personal cleansing composition having an anionic surfactant, a cationic deposition polymer, an aqueous carrier and a level of inorganic salt of from about 0 to about 1 wt %. The composition is substantially free of sulfates and has a % T of greater than about 80%. The composition can further comprise amphoteric surfactants. The composition remains phase stable and minimizes coacervate formulation until after dilution with water.
    Type: Grant
    Filed: October 10, 2018
    Date of Patent: March 21, 2023
    Assignee: The Procter & Gamble Company
    Inventors: Brian Xiaoqing Song, Brooke Michele Cochran, Howard David Hutton, III, Andrei Sergeevich Bureiko, Peter Herbert Koenig
  • Depilatory wax additive and process
    Patent number: 11607372
    Abstract: A depilatory wax additive and process. The depilatory wax additive may modify a depilatory hard wax composition to include visual, olfactory, or skin treatment components. A depilatory wax additive may include molded hard wax component and glitter, a color modifier, a scent modifier, or a skin treatment. A preexisting hard wax composition of solid particles may be heated to a liquid. The depilatory wax additive may be added to the liquefied preexisting hard wax composition, mixed, and heated to disperse the glitter, a color modifier, a scent modifier, or a skin treatment in the wax mixture.
    Type: Grant
    Filed: April 1, 2021
    Date of Patent: March 21, 2023
    Inventors: Norman D. Newsome, Jr., Kristen D. Newsome
  • Aromatic-based polyetheramine alkoxylates
    Patent number: 11603436
    Abstract: The present disclosure provides a polyetheramine alkoxylate compound containing aromatic groups in the hydrophobe allowing the compound to exhibit unique functionality, high performance and low cost, but without the toxicity and/or skin and eye irritation problems associated with conventional polyetheramine compounds.
    Type: Grant
    Filed: October 30, 2018
    Date of Patent: March 14, 2023
    Assignee: HUNTSMAN Petrochemical LLC
    Inventor: Matthew T. Meredith
  • Readily absorbable copolymer compositions for high strength sutures having enhanced strength retention post-implantation
    Patent number: 11596709
    Abstract: Novel surgical sutures and novel medical devices made from novel semi-crystalline, glycolide-rich A-B-A triblock copolymers of glycolide and lactide, wherein said B-segment is a fully amorphous random copolymer of glycolide and lactide, for long term medical applications are disclosed. The novel polymer compositions are useful for long term absorbable surgical sutures, meshes and other medical devices, especially for patients with compromised healing. The novel sutures have improved properties and improved breaking strength retention, while still substantially absorbing within about a 120-day period post-implantation.
    Type: Grant
    Filed: June 16, 2021
    Date of Patent: March 7, 2023
    Assignee: Ethicon, Inc.
    Inventors: Dennis D. Jamiolkowski, Christopher DeFelice, Sasa Andjelic, Brian M. Kelly, Marc Wisnudel, Daniel Steiger, Gaoyuan Gavin Chen
  • Microcapsules for controlled delivery of an active pharmaceutical ingredient
    Patent number: 11590084
    Abstract: The present invention relates a microcapsule that comprises an active pharmaceutical ingredient and a polymeric shell comprised of polymeric materials such as polyether, polyester, polyamine, polyamide, polyurea, polyurethane, polythiocarbamate, and polythiocarbonate. The outer surface of shell comprises surface functional groups such as hydroxide, primary amine, carboxylic acid, or protected forms thereof. These surface functional groups may be reacted further with reactants to place specific organic groups on the surface of the microcapsule. Such microcapsules are prepared by a modified interfacial condensation polymerization.
    Type: Grant
    Filed: April 28, 2017
    Date of Patent: February 28, 2023
    Inventors: Roman Bielski, Zbigniew Janusz Witczak
  • Dual phase products
    Patent number: 11571375
    Abstract: A discrete dispensed product comprising a first portion; and a second portion at least partially surrounding the first portion provides a premium and distinct appearance to consumers.
    Type: Grant
    Filed: December 18, 2020
    Date of Patent: February 7, 2023
    Assignee: The Procter & Gamble Company
    Inventors: Joseph Michael Zukowski, Sudeep Chakravarty, Yu Wang, Suxuan Gong
  • Pharmaceutical resinate compositions and methods of making and using thereof
    Patent number: 11564918
    Abstract: Disclosed herein are pharmaceutical compositions having a mixture of at least one active agent and an ion exchange resin, such that the composition releases about 75% or more of the at least one active agent within about 1 hour as measured by in-vitro dissolution in a USP Apparatus 2 (paddle) at about 50 rpm in about 900 ml 0.1N HCl at about 37° C. and related methods. Also disclosed herein are pharmaceutical compositions having a mixture of a drug susceptible to abuse, a non-opioid analgesic and an ion exchange resin, the composition further including at least one gelling agent and related methods.
    Type: Grant
    Filed: October 10, 2017
    Date of Patent: January 31, 2023
    Assignee: RHODES PHARMACEUTICALS L.P.
    Inventors: Gerard P. Frunzi, Sibao Chen, Rajeev A. Jain
  • Drug loaded nanoresin particles
    Patent number: 11559487
    Abstract: The present invention relates to nano-resin particles that are suitable for pharmaceutical use and their use in the pharmaceutical field. The present invention provides nano-sized resin particles having a particle size distribution characterized in that D90 value is between 200 nanometers to 900 nanometer and D10 value is not less than 50 nanometers, wherein the nano-resin particles are in pure form and safe for pharmaceutical use. The present invention further relates to pharmaceutical compositions comprising these purified nano-resin particles and their use in the treatment of diseases.
    Type: Grant
    Filed: December 9, 2019
    Date of Patent: January 24, 2023
    Assignee: SUN PHARMA ADVANCED RESEARCH COMPANY LIMITED
    Inventors: Ajay Jaysingh Khopade, Arindam Halder, Shivam Umeshkumar Upadhyay
  • Preparation method and use of artificial exosome complex
    Patent number: 11559477
    Abstract: A preparation method and use of an artificial exosome complex are provided. Raw materials for preparing the artificial exosome complex include linear polyethyleneimine (PEI) and hyaluronic acid (HA). The linear PEI can be obtained through the HA-PEI preparation process of the present disclosure, and most PEI is branched currently. According to the HA-PEI preparation method, HA-PEI with a specific molecular weight can be quantitatively prepared. The preparation process involves controllable operation steps, and thus can be used for large-scale industrial production. The prepared HA-PEI can promote the absorption of an encapsulated active substance by deep skin cells through the ligand activity of HA and the membrane permeability of linear PEI.
    Type: Grant
    Filed: April 27, 2020
    Date of Patent: January 24, 2023
    Assignee: SHANGHAI CHEERMORE BIOLOGICAL TECHNOLOGY CO., LTD.
    Inventors: Caibin Zhu, Junxiang Li