Abstract: An implantable electrode device includes a carrier made of a polymer material, at least one measurement electrode formed by an electrically conducting pad located on the carrier, wherein the electrically conducting pad has a contact surface, a barrier layer enclosing the carrier by covering all surfaces of the carrier, wherein the contact surface of the electrically conducting pad is exposed to an outside environment, at least one electrically conducting trace, and at least one electrically conducting terminal. The electrically conducting trace can electrically connect the measurement electrode to the electrically conducting terminal. A surface of the implantable electrode device on a side on which the measurement electrode is located can have a maximum valley depth or a maximum peak height between the contact surface of the measurement electrode and a meanline of a surface of the implantable electrode device, excluding measurement electrodes, being equal to or smaller than 100 micrometres.

Abstract: An intravascular catheter for nerve activity ablation and/or sensing includes one or more needles advanced through supported guide tubes (needle guiding elements) which expand to contact the interior surface of the wall of the renal artery or other vessel of a human body allowing the needles to be advanced though the vessel wall into the extra-luminal tissue including the media, adventitia and periadvential space. The catheter also includes structures which provide radial and lateral support to the guide tubes so that the guide tubes open uniformly and maintain their position against the interior surface of the vessel wall as the sharpened needles are advanced to penetrate into the vessel wall. Electrodes at the distal ends of the guide tubes allow sensing of nerve activity before and after attempted renal denervation. In a combination embodiment ablative energy or fluid is delivered to ablate nerves outside of the media.

Abstract: The present disclosure relates to a device configured to be adhered to the surface of a mammal for recording physiological signals. The device may include a housing enclosing a circuit board and a flexible wing extending from the housing. The device may include an electrode coupled to the flexible wing and an electrical trace for transmitting an electrical signal between the electrode and the circuit board. The electrical trace may have an insulator with a conductive material and resistors printed on the surface of the insulator. The trace layer may include conductive vias for transmitting the signal from a bottom of the trace layer to a top of the trace layer. The housing may include a battery having a battery terminal connector configured to provide electrical access to both terminals on a single side of the battery. The housing may include a floating trigger button.

Abstract: A conductive human interface has a fabric layer with an interior surface and an exterior surface. A soft coating overlies the interior surface of the fabric layer. An electrode or sensor is included to connect with a residual limb. A conductive path connects the electrode or sensor with an electrical connector which, in turn connects with a prosthetic or other assistive device. The conductive path includes a conductor having a section overlying the fabric layer. The overlying section of the conductor can be cord of conductive thread. A nonconductive support thread can extend through the fabric layer from the exterior surface to the interior surface, and further around the conductor to secure the overlying section of the conductor to the fabric layer.

Abstract: An apparatus for measuring patient data includes a frame having a plurality of electrode hubs. Each hub can include one or more electrode members. The frame can be configured to receive a head of a patient. Each of the electrode hubs can have a single electrode member or a plurality of electrode members that extend from or are connected to an outer member for contacting a scalp of the head of the patient. The outer member can have at least one circuit configured to transmit data received by at least one of the electrode members to a measurement device via a wireless communication connection (e.g. Bluetooth, near field communication, etc.) or a wired communication connection.

Abstract: Physiological monitoring can be provided through a lightweight wearable monitor that includes two components, a flexible extended wear electrode patch and a reusable monitor recorder that removably snaps into a receptacle on the electrode patch. The wearable monitor sits centrally on the patient's chest along the sternum oriented top-to-bottom. The placement of the wearable monitor in a location at the sternal midline, with its unique narrow “hourglass”-like shape, significantly improves the ability of the wearable monitor to cutaneously sense cardiac electrical potential signals, particularly the P-wave and the QRS interval signals indicating ventricular activity in the ECG waveforms. In particular, the ECG electrodes on the electrode patch are tailored to be positioned axially along the midline of the sternum for capturing action potential propagation in an orientation that corresponds to the aVF lead used in a conventional 12-lead ECG that is used to sense positive or upright P-waves.

Abstract: A medical apparatus includes a shaft for insertion into an organ of a patient, an expandable frame, a plurality of diagnostic electrodes, a respective plurality of reference electrodes, and a processor. The expandable frame is coupled to a distal end of the shaft, extending along a longitudinal axis and including a plurality of expandable spines disposed about the longitudinal axis. The plurality of diagnostic electrodes, disposed on external surfaces of the expandable spines, are configured to sense diagnostic signals when in contact with tissue. The respective plurality of reference electrodes, disposed on internal surfaces of the expandable spines directly opposite the diagnostic electrodes, is electrically insulated from the tissue and is configured to sense interfering signals.

Abstract: Physiological monitoring can be provided through a lightweight wearable monitor that includes two components, a flexible extended wear electrode patch and a reusable monitor recorder that removably snaps into a receptacle on the electrode patch. The wearable monitor sits centrally (in the midline) on the patient's chest along the sternum oriented top-to-bottom. The placement of the wearable monitor in a location at the sternal midline, with its unique narrow “hourglass”-like shape, significantly improves the ability of the wearable monitor to cutaneously sense cardiac electrical potential signals, particularly the P-wave and, to a lesser extent, the QRS interval signals indicating ventricular activity in the ECG waveforms. Additionally, the monitor recorder includes an ECG sensing circuit that measures raw cutaneous electrical signals and performs signal processing prior to outputting the processed signals for sampling and storage.

Abstract: Monitoring muscle data can include one or more fully flexible sensor patches having sensor modules configured to sense muscle data, data processing modules, transmitter modules configured to transmit the muscle data, and a microcontroller configured to control the modules on one patch side and an adhesive layer on the other patch side; a wearable mobile hub having one or more of a receiver, transmitter, and/or transceiver module configured to be operably coupled with the one or more sensor patches so as to receive muscle data therefrom and a muscle data processing unit configured to process the received muscle data, and one or more user feedback interfaces to provide processed muscle data to the one or more user feedback interfaces; and a base station configured for receiving, storing, and analyzing the muscle data for one subject received from the mobile hub in comparison with one or more other subjects.

Abstract: An extended wear electrocardiography patch is provided. An integrated flexible circuit includes a single piece of material and has an upper end and a lower end opposite the upper end. A mirror image of the upper end extends from at least a portion of one side of the upper end and folds over the upper end. One circuit trace is positioned on the upper end and one circuit trace is positioned on the lower end. Electrical pads are located on a contact surface of the upper end and on an outward facing surface of the mirror image of the upper end. An electrocardiographic electrode is positioned on the contact surface of the upper end and another electrocardiographic electrode is positioned on a contact surface of the lower end. A battery is directly adhered to the outward facing surface of the mirror image of the upper end.

Abstract: An electrode assembly that includes an electrically conductive layer, a first impedance reduction system, and a second impedance reduction system. The electrically conductive layer forms an electrode portion of the electrode assembly and a first surface to be placed adjacent a person's skin. The first impedance reduction system is configured to dispense a first amount of an electrically conductive gel onto the first surface of the electrically conductive layer in response to a first activation signal. The second impedance reduction system is configured to dispense a second amount of the electrically conductive gel onto the first surface of the electrically conductive layer in response to a second activation signal.

Abstract: Electrode carrier for electrophysiological measurements, including a flexible substrate, a plurality of contact pads attached to a substrate surface, wherein each contact pad includes conductive means for accommodating an electrode for electrophysiological measurement, first connecting means attached to the substrate for communicatively connecting the contact pads to a signal processing device. The first connecting means includes a plurality of conductive tracks on the substrate surface for electrically connecting the plurality of contact pads, wherein each conductive track corresponds to at least one contact pad. The substrate has at least two inextendible sections for accommodating the contact pads, wherein the sections interconnected by an extendible section. Each extendible section comprises at least one warpable member of flexible material. At least one of the warpable members accommodates at least one of the conductive tracks.

Abstract: An electrode interface system for providing a connection between at least one electrode and a maternal-fetal monitor, wherein the interface system converts electrical muscle activity captured by the electrode(s) into uterine activity data signals for use by the maternal-fetal monitor. The electrode interface system of the invention preferably includes a conversion means for converting the signals from the electrode(s) into signals similar to those produced by a tocodynometer.

Abstract: An intravascular catheter system for cardiac mapping is disclosed which includes a housing having opposed proximal and distal portions, an elongated catheter shaft operatively associated with the distal portion of the housing, an elongated electrical conduit operatively associated with the proximal portion of the housing and an elongated irrigation conduit operatively associated with the proximal portion of the housing, wherein an irrigated basket assembly is operatively associated with a distal end portion of the catheter shaft and it includes a plurality of circumferentially arranged electrically insulated tubular splines each having a plurality of longitudinally spaced apart mapping electrodes thereon.

Abstract: The invention provides a neck-worn sensor that is a single, body-worn system that measures the following parameters from an ambulatory patient: heart rate, pulse rate, pulse oximetry, respiratory rate, temperature, thoracic fluid levels, stroke volume, cardiac output, and a parameter sensitive to blood pressure called pulse transit time. From stroke volume, a first algorithm employing a linear model can estimate the patient's pulse pressure. And from pulse pressure and pulse transit time, a second algorithm, also employing a linear algorithm, can estimate systolic blood pressure and diastolic blood pressure. Thus, the sensor can measure all five vital signs along with hemodynamic parameters. It also includes a motion-detecting accelerometer, from which it can determine motion-related parameters such as posture, degree of motion, activity level, respiratory-induced heaving of the chest, and falls.

Abstract: The present disclosure relates to a cardiac monitoring device and systems/methods relating to same. Preferred embodiments may include adhesive layers having channels for transpiring moisture to promote long term adhesion of the device to a subject. The adhesive layer may be surrounded by a non-adhesive lining to inhibit substrate layers from folding under the adhesive. In some embodiments, the adhesive layer may be replaceable. In some embodiments, the adhesive layer may extend beneath a substrate coupled to a housing but not be adhered to the overlying substrate layers. The angles of the edges of the adhesive layer may be configured to minimize peeling forces. Substrate layers above the adhesive layer may be perforated to promote transpiration of moisture and/or provide conformability to the substrate. The perforations may promote anisotropic resistance to compression and/or extension of the substrate.

Abstract: A manipulable portion of a catheter system advances out of a lumen of a catheter sheath at a distal end of a shaft, which is also within the lumen of the catheter sheath. The catheter system causes different advancement and retraction trajectories of a manipulable portion out of and into the lumen based at least upon different relative movements between the catheter sheath and the shaft. A projection and a corresponding receiver may be used to control relative positioning of the catheter sheath and the shaft, as well as to control positioning of the manipulable portion. The catheter system may control metering rates of a control element coupled to the manipulable portion during advancement and retraction of the manipulable portion. A control element of the catheter system has varying amounts of length outside a distal end of the catheter sheath during advancement and retraction of the manipulable portion.

Abstract: The present disclosure relates to a device configured to be adhered to the surface of a mammal for recording physiological signals. The device may include a housing enclosing a circuit board and a flexible wing extending from the housing. The device may include an electrode coupled to the flexible wing and an electrical trace for transmitting an electrical signal between the electrode and the circuit board. The electrical trace may have an insulator with a conductive material and resistors printed on the surface of the insulator. The trace layer may include conductive vias for transmitting the signal from a bottom of the trace layer to a top of the trace layer. The housing may include a battery having a battery terminal connector configured to provide electrical access to both terminals on a single side of the battery. The housing may include a floating trigger button.

Abstract: A sensing system includes a sensor including a flexible substrate and a graphene oxide sensing element deposited on the flexible substrate. The graphene oxide sensing element has first and second sides. First and second electrical connectors coupled to the first and second sides of the graphene oxide sensing element, respectively. A power source is coupled to the first and second electrical connectors of the sensor and is adapted to apply a constant voltage to the sensor. The sensing system also includes a measurement element measuring a current in the graphene oxide sensing element due to the constant voltage and a calculation element calculating an electrical resistance of the graphene oxide sensing element based on the electrical current and the constant voltage and calculating a condition at a location of the sensor based on a relationship between the electrical resistance and the condition for the graphene oxide sensing element.

Abstract: A sensor array can be integrally defined in a fabric headgear. A gel distribution module can be connected to each sensor of the sensor array. Each module can include an outer part that is connectable to a second inner part so that the fabric of the headgear and sensor are between the inner and outer parts. Each module can be configured to facilitate the distribution of a gel onto a scalp of a patient and into contact with the sensor via actuation of an actuator of the module to permit rapid deployment of the gel at the sensor specific locations on the head of a patient. The gel can be distributed directly onto skin of the scalp even when the patient has hair at the sensor location. The sensor array can be positioned so that asymmetrical positioning of the sensors on a patient's head is detectable.