Abstract: A method for determining a lesion location in a patient for biopsy along X, Y, and Z axes. The method includes positioning the patient in an examination device to collect examination images showing the lesion. The method includes positioning the patient in a biopsy device configured for holding the patient during the biopsy and collecting a biopsy image of the patient using the biopsy device. The method includes analyzing the biopsy image to determine a measured x-coordinate and a measured y-coordinate of the lesion along the X and Y axes, respectively, analyzing the examination images to determine a calculated z-coordinate along the Z axis of the lesion, and determining the location of the lesion based on the measured x-coordinate and the measured y-coordinate from the biopsy image and the calculated z-coordinate determined from the one or more examination images.

Abstract: A treatment support device includes an irradiation unit configured to emit treatment light to a medical agent, a fluorescence intensity acquisition unit configured to acquire fluorescence intensity of fluorescence emitted by the fluorescent material of the medical agent excited by the treatment light, and a treatment light imaging unit configured to capture a treatment light image based on the treatment light. The treatment support device is configured such that a first region of interest is capable of being set based on a position of the treatment light in the treatment light image captured by the treatment light imaging unit, the first region of interest being a region for selectively acquiring a temporal change in the fluorescence intensity acquired by the fluorescence intensity acquisition unit.

Abstract: The present description concerns a support helmet (130) for a medical imaging or treatment device, comprising a head cap (131) provided with a plurality of through openings (133), each opening being adapted to receiving an elementary imaging or treatment module (110) assembled in the opening so as to slide along an axis substantially orthogonal to the head cap.

Abstract: An imaging condition acquisition unit acquires an imaging condition in a case in which a subject is imaged in a state in which an object is interposed between the subject and a radiation detector. A body thickness derivation unit derives a body thickness distribution of the subject based on the radiation image and the imaging condition. A characteristic acquisition unit acquires a radiation characteristic of the object in accordance with the body thickness distribution. A ray distribution unit derives a primary ray distribution and a scattered ray distribution of the radiation detected by the radiation detector by using the imaging condition, the body thickness distribution, and the radiation characteristic.

Abstract: An apparatus (100) for assessing condition of the bone tissue of a patient's bone region (21), comprising an ultrasound device (11) that has a probe for transmitting/receiving ultrasounds along a plurality of ultrasound propagation lines (15 i) and for receiving in response from the bone region (21) a plurality of raw reflected ultrasound signals (36,38); a computer configured generating and displaying a sonographic image and for extracting at least one frequency spectrum (43i,44i,47,48) starting from at least one part of the said plurality of raw reflected ultrasound signals (36,38) coming from corresponding points (34) of the bone region (21), each having a plurality of harmonic components wherein to each frequency (v) of the frequency range an intensity is associated (A) of a portion of one of the raw reflected ultrasound signals.

Abstract: Systems and methods are provided for in vivo pre-surgical characterization of lenses, such as cataractous lenses. A method comprises obtaining an electromagnetically-measured value related to the axial thickness of the lens, obtaining an ultrasound-measured value related to the axial thickness of the lens, calculating a relationship value based upon the electromagnetically-measured value and the ultrasound-measured value, and determining a mechanical property value based upon the calculated relationship value. The mechanical property may relate to lens hardness, rigidity, or density, or the amount of energy for a phacoemulsification procedure. A system may comprise an optical interferometer for measuring data to obtain the electromagnetically-measured value and an ultrasound biometer for measuring data to obtain the ultrasound-measured value.

Abstract: Embodiments discussed herein facilitate determination of a response to treatment and/or a prognosis for a tumor based at least in part on features of tumor-associated vasculature (TAV). One example embodiment is a method, comprising: accessing a medical imaging scan of a tumor, wherein the tumor is segmented on the medical imaging scan; segmenting tumor-associated vasculature (TAV) associated with the tumor based on the medical imaging scan; extracting one or more features from the TAV; providing the one or more features extracted from the TAV to a trained machine learning model; and receiving, from the machine learning model, one of a predicted response to a treatment for the tumor or a prognosis for the tumor.

Abstract: An intraluminal ultrasound imaging device includes a flexible elongate member configured to be positioned within a body lumen of a patient. The flexible elongate member includes a proximal portion and a distal portion. The device also includes an ultrasound imaging assembly disposed at the distal portion of the flexible elongate member. The ultrasound imaging assembly is configured to obtain imaging data of the body lumen. The ultrasound imaging assembly includes a transducer array including a substrate, a silicon oxide layer disposed over the substrate, and a plurality of rows of micromachined ultrasound transducer elements disposed on the silicon oxide layer. Two of the plurality of rows of micromachined ultrasound transducer elements are spaced apart by a trench formed by etching through a screen formed in the silicon oxide layer. Associated devices, systems, and methods are also provided.

Abstract: A system and method are provided for creating an image including quantified flow within vessels of a subject. The method includes providing a single-sweep, three-dimensional (3D) image volume acquired from a subject during a single pass of a computed tomography (CT) imaging system as the subject receives a dose of a contrast agent and determining a phase shift corresponding to pulsatile contrast in vessels within the single-sweep, 3D image volume. The method further includes quantifying a flow through the vessels within the single-sweep, 3D image volume using the phase shift and generating a report including indicating flow through the vessels within the 3D image volume.

Abstract: The inventions provided herein relate to tissue markers and uses thereof, e.g., to mark a target tissue site (e.g., a biopsy site in a breast tissue) or to produce a cell scaffold. The tissue markers described herein are designed to be resistant to fast migration (e.g., immediate migration after implantation through a needle track) and slow migration (e.g., over an extended period of time) upon implantation at a target tissue site (e.g., a biopsy site in a breast tissue), without using an adhesive. Additionally or alternatively, the tissue markers described herein can be readily detectable by at least one imaging modality, e.g., but not limited to magnetic resonance imaging, X-ray imaging, ultrasound imaging, or a combination thereof.

Abstract: The present teachings generally provide for a surgical navigation system for use with an x-ray imaging device. The x-ray imaging device acquires x-ray images of an anatomical structure of interest at an angular position. The surgical navigation system includes a localizer with a tracking sensor, a gravity vector sensor coupled to the tracking sensor, a tracking device configured to be coupled to the C-arm so as to be movable with the C-arm between a plurality of angular positions. The tracking device comprises a tracking element detectable by the tracking sensor. A computer processor is operatively coupled with the localizer and configured to implement an imaging routine that receives tracking data from the tracking sensor and a gravity vector from the gravity vector sensor, generating an image vector indicative of the angular position at which the x-ray image was acquired.

Abstract: A system using images of a subject to assist in visualization of hidden portions of the subject is disclosed. The system may illustrate the images with a wearable display. The images may be displayed in an augmented or mixed reality manner.

Abstract: A method of full-field or “ping-based” Doppler ultrasound imaging allows for detection of Doppler signals indicating moving reflectors at any point in an imaging field without the need to predefine range gates. In various embodiments, such whole-field Doppler imaging methods may include transmitting a Doppler ping from a transmit aperture, receiving echoes of the Doppler ping with one or more separate receive apertures, detecting Doppler signals and determining the speed of moving reflectors. In some embodiments, the system also provides the ability to determine the direction of motion by solving a set of simultaneous equations based on echo data received by multiple receive apertures.

Abstract: A display may display a region of an anatomy that is not within the field of effect of an instrument. The additional views may assist in determining a location and orientation of an instrument. The instrument may be tracked with a tracking system to make the determination of image data to display.

Abstract: A method of identifying and locating tissue abnormalities in a biological tissue includes irradiating an electromagnetic signal, via a probe defining a transmitting probe, in the vicinity of a biological tissue. The irradiated electromagnetic signal is received at a probe, defining a receiving probe, after the signal is scattered/reflected by the biological tissue. Blood flow information pertaining to the biological tissue is provided. Based on the received irradiated electromagnetic signal and the blood flow information, tissue properties of the biological tissue are reconstructed. A tracking unit determines the position of at least one of the transmitting probe and the receiving probe while the step of receiving is being carried out, the at least one probe defining a tracked probe. The reconstructed tissue properties are correlated with the determined probe position so that tissue abnormalities can be identified and spatially located.

Abstract: A system, device, and accompanying software for the remote, three-dimensional, and high-throughput imaging and analysis of human lesions, across a range of wavelengths, lens radii and imaging sensors. This system, device, and software generates and analyses of tumor images at infrared wavelengths through the use of miniaturized, liquid lenses. It has a number of clinical, diagnostic, research, and other imaging applications, including the remote, three-dimensional, and high-throughput imaging and analysis of human cancer tumors.

Abstract: Systems for guiding placement of surgical ports on a body include an image capture device configured to capture an image of an operating environment and generate image data based on the captured image, a display device, and a computing device configured to obtain information regarding a location of a surgical site within the body, receive the image data from the image capture device, generate graphical guidance for placing a surgical port on the body based on the location of the surgical site within the body and the image data, and cause the display device to display the generated graphical guidance.

Abstract: Provided are systems and methods for location sensor-based branch prediction. In one aspect, the method includes determining a first orientation of an instrument based on first location data generated by a set of one or more location sensors for the instrument and determining a second orientation of the instrument at a second time based on second location data. A distal end of the instrument is located within a first segment of a model at the first time and the second time and the first segment branches into two or more child segments. The method also includes determining data indicative of a difference between the first orientation and the second orientation and determining a prediction that the instrument will advance into a first one of the child segments based on the data indicative of the difference.

Abstract: A method for determining a physical characteristic on a punctual location inside a medium, comprising the steps of: sending an emitted sequence comprising emitted pulses having different amplitudes, receiving a received sequence comprising received pulses corresponding to echoes of emitted pulses, calculating a phase difference between the received pulses relative to the emitted pulses, and determining the physical characteristic on the bases of a phase difference.

Abstract: Methods for using registered real-time images and prior-time anatomic images during an image-guided procedure are provided herein. An exemplary method includes obtaining a three-dimensional image of a patient anatomy and a portion of a medical instrument disposed therein. The three-dimensional image includes image information characterizing a shape of the portion of the medical instrument. A processing device segments the portion of the medical instrument from the three-dimensional image. Shape data is obtained from the portion of the medical instrument while the portion is positioned within the patient anatomy, and the processing device registers the segmented shape of the portion of the medical instrument with the shape data from the portion of the medical instrument.