Abstract: A color image sensor captures a reflected image of narrowband light having a wavelength range in which an extinction coefficient varies with a change in an oxygen saturation level of hemoglobin in blood. Thereby a first blue signal, a first green signal, and a first red signal are obtained. The color image sensor captures a reflected image of white light. Thereby a second blue signal, a second green signal, and a second red signal are obtained. Only an oxygen saturation level, out of two or more types of biological functional information including a blood volume and the oxygen saturation level, is obtained based on the first blue signal, the second green signal, and the second red signal. The oxygen saturation level is visualized to produce an oxygen saturation image.

Abstract: Embodiments of the invention provide a system, apparatus and methods for measurement of biometric data of a diver. In many embodiments, the system includes a mouthpiece having a sensor device comprising a light emitter and detector configured to emit and detect light at a wavelength having an absorbance correlated with a level of a blood gas saturation e.g., oxygen, nitrogen, CO2. The emitter is positioned to emit light onto oral tissue of the diver and the detector positioned to detect light which is received from the oral tissue either by transmittance of light through the oral tissue or by reflection of light from the tissue. The target oral tissue can include one or both of gum or buccal tissue. Such embodiments allow data to be collected without having to wear additional sensors or measurement devices and allow for measurement of blood gas levels as the diver breaths through their mouthpiece.

Abstract: Methods of exerting magnetic forces to separate magnetic particles disposed in a portion of subsurface vasculature using a wearable device are provided. The magnetic forces can act to attract, slow, speed, or otherwise influence the magnetic particles in various applications. In some examples, different magnetic forces are exerted on respective sets of magnetic particles to separate the respective sets of magnetic particles. In some examples, similar magnetic forces are exerted on sets of magnetic particles, and separation of the sets of magnetic particles is related to properties of the sets of magnetic particles and/or of the environment of the sets of magnetic particles. In some embodiments, the magnetic particles are configured to bind to an analyte of interest. The separation of the magnetic particles can enable detection of one or more properties of the analyte, modification of the analyte, and/or extraction of the analyte bound to the magnetic particles.

Abstract: A physiological parameter tracking system has a reference parameter calculator configured to provide a reference parameter responsive to a physiological signal input. A physiological measurement output is a physiological parameter derived from the physiological signal input during a favorable condition and an estimate of the physiological parameter according to the reference parameter during an unfavorable condition.

Abstract: A system for measuring the luminance and temperature of a light source element of a spectrophotometric device is provided. The system includes a photodiode, a luminance measuring device, a temperature measuring device, a first switch, and a controller. The photodiode is operable to receive light signals emitted by the light source element and passing through a subject's body tissue. The luminance measuring device is operable to measure luminance of the light signals received by the photodiode. The temperature measuring device is operable to measure the temperature of the photodiode. The first switch is operable to connect the photodiode to the luminance measuring device or the temperature measuring device. The controller is operable to control the connection of the first switch.

Abstract: An object information acquiring apparatus comprises an irradiating unit which irradiates light on an object; a holding member which includes a light-absorbing member whose optical characteristics with respect to irradiated light are known and which holds the object; a detector which detects acoustic waves generated by tissue in the object and the light-absorbing member due to light irradiation; and a computing unit which calculates optical characteristics of the tissue in the object and the light-absorbing member by using the detected acoustic waves and which corrects the optical characteristics of the tissue in the object by using the calculated optical characteristics of the light-absorbing member and the known optical characteristics.

Abstract: The invention provides a body-worn system that continuously measures pulse oximetry and blood pressure, along with motion, posture, and activity level, from an ambulatory patient. The system features an oximetry probe that comfortably clips to the base of the patient's thumb, thereby freeing up their fingers for conventional activities in a hospital, such as reading and eating. The probe secures to the thumb and measures time-dependent signals corresponding to LEDs operating near 660 and 905 nm. Analog versions of these signals pass through a low-profile cable to a wrist-worn transceiver that encloses a processing unit. Also within the wrist-worn transceiver is an accelerometer, a wireless system that sends information through a network to a remote receiver, e.g. a computer located in a central nursing station.

Abstract: Systems and electronic processes for reducing electronic alarms in a medical patient monitoring system. For example, a system for reducing electronic alarms can include an optical sensor and one or more hardware processors in electronic communication with the optical sensor. The one or more hardware processors can be programmed to measure oxygen saturation values of a patient over a first period of time, determine if at least one oxygen saturation value obtained over the first period of time exceeds a first alarm threshold, determine whether a first alarm should be triggered based on the determination that the at least one oxygen saturation value obtained over the first period of time exceeds the first alarm threshold, determine a second alarm threshold to be applied during a second period of time subsequent to the first period of time, the second alarm threshold replacing the first alarm threshold.

Abstract: Blood oxygenation sensors including high-aspect-ratio photodetector elements are discussed herein. Such high-aspect-ratio photodetector elements may provide improved signal-strength-to-power-consumption performance for blood oxygenation sensors incorporating such photodetector elements as compared with blood oxygenation sensors incorporating, for example, square photodetector elements.

Abstract: A sensing system and method for sensing a component in a liquid is disclosed. The system comprises a microfluidic channel, the microfluidic channel comprising a first end and a second end, wherein the microfluidic channel is open at the first end and closed at the second end. The system also comprises at least one measurement sensor positioned adjacent the first end, the measurement sensor being arranged for detecting a measurement signal and a reference sensor positioned in the microfluidic channel adjacent the second end, the reference sensor being arranged for detecting a reference signal of the liquid. The system further is configured for combining the measurement signal and the reference signal so as to filter out background influences.

Abstract: A method including placing a portion of a foot of a newborn in a device, the device including a light emitter and a corresponding receiver coupled on opposite sides of the device, the device further including a processor for processing data from the light emitter and receiver; and determining a presence of congenital heart disease. An apparatus including a body including a chamber of a size to accommodate a portion of a newborn's foot; at least one light emitter and a corresponding detector coupled on opposite sides of the body, the emitter configured to emit light of a prescribed wavelength into the chamber; and a processor coupled to the body and configured to receive a signal from the at least one detector.

Abstract: Light beams emitted from one or more light sources may be directed into an abdomen of a pregnant mammal toward a fetus contained therein. Some of the light may be reflected by the pregnant woman and fetus and received at a detector over a first time. A photo detector into an electronic reflected signal, which may be communicated to a computer, may then convert the received light. The electronic reflected signal may then be processed and/or analyzed to isolate a portion of the electronic reflected signal reflected from the fetus. The isolated portion of the electronic reflected signal reflected from the fetus may then be analyzed to determine a fetal hemoglobin oxygen saturation level of the fetus. An indication of the fetal hemoglobin oxygen saturation level may then be provided to an operator by way of, for example, a computer display.

Abstract: Some embodiments relate to a device, method, and/or computer-readable medium storing processor-executable process steps to remove a component of a signal corresponding to ambient light in a photoplethysmographic sensor device, including capturing a first detected light signal representing an ambient light at a first time, causing a light emitter to generate a source light signal driven at a first level, capturing a second detected light signal representing the source light signal after interacting with a user's tissue plus the first detected light signal, generating a first output signal based on the second detected light signal adjusted by the first detected light signal, causing the light emitter to generate a source light signal driven at a second level, capturing a third detected light signal representing the source light signal driven at the second level after interacting with the user's skin plus the first detected light signal, and generating a second output signal based on the third detected light sig

Abstract: A method for non-invasive blood glucose monitoring includes the following steps. At least one ray of light is emitted from at least one light source. The light emitted from the light source is leaded into an eyeball and focused on the eyeball through a first beam splitter. The reflected light reflected from the eyeball is transmitted through the first beam splitter to a set of photo detectors. Optical angular information and absorption energy information of the reflected light transmitted to the set of photo detectors are measured. Optical angular difference and absorption energy difference resulting from the light emitted from the light source and the reflected light transmitted to the set of photo detectors are obtained. Glucose information is obtained by analyzing the optical angular difference and the absorption energy difference, and since glucose information has a corresponding relationship with blood glucose information, blood glucose information may be read.

Abstract: The present invention provides a pulse oximeter of the portable type, which is possible to carry around and to use widely regardless of the adult, the infant, the newborn baby, and which can keep the finger still for performing the precise measurement. The pulse oximeter 100 comprises a measurement cavity 110 for accepting the examined portion (for example finger) of the subject, a measurement device 120 including a light emitting part 121 and a photo detecting part 122 facing between the measurement cavity 110, a filling element 140 formed from a material that the light used for the measurement can penetrate. The height and the curvature of the inner surface of the filling element 140 is larger than that of the outer surface of the filling element 140. The filling element 140 converts the height and the curvature of the inner space.

Abstract: Disclosed is a flexible insert (100) for placement on the human eye, comprising a light source (110) in said insert such that light emitted from the light source is shielded from the human eye upon correct placement of the insert on the human eye, a light-responsive material (120) placed in the light path of the light source, said light-responsive material emitting light upon stimulation by the light from said light source, the intensity of said stimulated emission being sensitive to a chemical interaction of the light-sensitive material with an analyte of interest, a photodetector (130) for detecting the light emitted by the light-responsive material; and a transmitter (140) coupled to the photodetector for transmitting a photodetector reading. The insert may be used in conjunction with a reader for automated monitoring of an analyte of interest such as glucose in the tear fluid of its wearer.

Abstract: A processor provides signal quality based limits to a signal strength operating region of a pulse oximeter. These limits are superimposed on the typical gain dependent signal strength limits. If a sensor signal appears physiologically generated, the pulse oximeter is allowed to operate with minimal signal strength, maximizing low perfusion performance. If a sensor signal is potentially due to a signal induced by a dislodged sensor, signal strength requirements are raised. Thus, signal quality limitations enhance probe off detection without significantly impacting low perfusion performance. One signal quality measure used is pulse rate density, which defines the percentage of time physiologically acceptable pulses are occurring. If the detected signal contains a significant percentage of unacceptable pulses, the minimum required signal strength is raised proportionately.

Abstract: Apparatuses and methods are disclosed for identifying with a single, small, intelligent activity monitor a particular type of activity from among a plurality of different activities. The monitor may include a multi-axis accelerometer and microcontroller configured to combine and process accelerometer data so as to generate features representative of an activity. The features may be processed to identify a particular activity (e.g., running, biking, swimming) from among a plurality of different activities that may include activities not performed by a human subject. An intelligent activity monitor may be configured to operate as a versatile sensor, or to operate in combination with a versatile sensor, to further receive and process physiological data and compute a fitness metric for a subject.

Abstract: An apparatus for non-invasive glucose monitoring includes a light source for emitting at least one ray of light; a first beam splitter, a set of photo detectors for measuring optical rotatory distribution (ORD) information and absorption energy information; a reference component receiving the light from the first beam splitter, and the light reflected by the reference component being transmitted to the set of photo detectors by the first beam splitter, wherein the light emitted from the light source is transmitted to the set of photo detectors by the first beam splitter and the eyeball to form a first optical path, the light emitted from the light source is transmitted to the set of photo detectors by the first beam splitter and the reference component to form a second optical path; and a processing unit receiving and processing the ORD information and the absorption energy information to obtain a glucose information.

Abstract: An adaptive alarm system is responsive to a physiological parameter so as to generate an alarm threshold that adapts to baseline drift in the parameter and reduce false alarms without a corresponding increase in missed true alarms. The adaptive alarm system has a parameter derived from a physiological measurement system using a sensor in communication with a living being. A baseline processor calculates a parameter baseline from a parameter trend. Parameter limits specify an allowable range of the parameter. An adaptive threshold processor calculates an adaptive threshold from the parameter baseline and the parameter limits. An alarm generator is responsive to the parameter and the adaptive threshold so as to trigger an alarm indicative of the parameter crossing the adaptive threshold.