Abstract: An antioxidant sensor includes a first light source configured to emit light having a first wavelength onto an object; a second light source configured to emit light having a second wavelength onto the object; a third light source configured to emit light having a third wavelength onto the object, the first wavelength, the second wavelength, and the third wavelength being different from each other; a light receiver configured to receive light reflected or scattered from the object; and a processor configured to obtain a hemoglobin index by driving the first light source and the second light source, and to obtain an antioxidant signal of the object by driving the third light source based on the obtained hemoglobin index satisfying a condition.

Abstract: A method for the objective determination of capillary refill behavior on a human body surface in which a spatially and spectrally resolved optical detection is carried out by at least one detector device (1) at a skin surface area (2) having a predefined areal size and outer contour. Subsequently a predefined pressure p constant over the skin surface area (2) is exerted over a predefined time t1; and the pressure effect is ended after expiry of this time t1. The spatially and spectrally resolved optical detection is carried out by the detector device (1) and the respective capillary refill behavior is spatially and temporally determined at a time t2 up to which at least one first threshold value of the measurement values detected simultaneously with spatial resolution has reached the measurement value that had been optically detected before the start of the pressure effect.

Abstract: A biological material measuring apparatus includes an infrared light source unit to radiate infrared light in entirety or part of a wavelength region including absorption wavelengths of a biological material, a prism to cause the infrared light radiated from the infrared light source unit to pass therethrough and emit the infrared light to a living body surface while being in contact with the living body surface, a light source to radiate light of a wavelength in a visible light region or a near infrared region to the prism, and a light position detector to detect a path of light from the light source by detecting light from the light source which is emitted from the prism.

Abstract: A method for providing notification regarding one or more analytes includes detecting an amount of each of the one or more analytes using a non-invasive sensor, determining a notification to present based on the amount of at least one of the one or more analytes and notification criteria using a processor, and sending an instruction directing presentation of the notification. The method can further include presenting the notification. The notification can include vibration, sound, or visible components such as light, text, or images. The notification criteria can include upper thresholds, lower thresholds, or the analyte being within or outside of bounded ranges. Systems performing the method can include the sensor and optionally one or more of a mobile device and a remote server, and the notification can be presented in a device including the sensor or a separate device such as the mobile device.

Abstract: A wearable module assembly for an optical measurement system includes a first wearable module, a second wearable module, and a connector. The first and second wearable modules each include a light source configured to emit a light pulse toward a target within a body of a user, a housing that houses the light source and the plurality of detectors and includes a substantially hexagonal surface that faces a surface of the body of the user when the wearable module assembly is worn by the user, and a plurality of detectors each positioned at a fixed distance from the first light source and each configured to detect a set of photons included in the light pulse after the set of photons are scattered by the target. The connector directly connects the first wearable module and the second wearable module at mutually-facing side surfaces of the respective housings.

Abstract: An oximeter probe that takes into account tissue color (e.g., skin color or melanin content) to improve accuracy when determining oxygen saturation of tissue. Light is transmitted from a light source into tissue having melanin (e.g., eumelanin or pheomelanin). Light reflected from the tissue is received by a detector. A compensation factor is determined to account for absorption due to the melanin. The oximeter uses this compensation factor and determines a melanin-corrected oxygen saturation value.

Abstract: A system for measuring capillary refill time includes a wearable device and a control unit. The wearable device includes a force sensor to obtain a force signal and an optical sensor to obtain an optical signal. The system ensures that an applied force is acceptable in both magnitude and duration, and that a duration over which the applied force is released or removed is acceptable. These factors can establish that a capillary refill time determined or calculated therein is accurate. The system can also determine the capillary refill time based on the force and optical signals obtained by the force and optical sensors, respectively.

Abstract: A sensor (e.g., an optical sensor) that may be implanted within a living animal (e.g., a human) and may be used to measure an analyte (e.g., glucose or oxygen) in a medium (e.g., interstitial fluid, blood, or intraperitoneal fluid) within the animal. The sensor may include a sensor substrate, electrode or housing, an analyte indicator covering at least a portion of the sensor, and one or more optical signal stabilizing additives in an environment of the sensor.

Abstract: A glove comprising a set of electrocardiogram leads, the set of electrocardiogram leads including: (a) a plurality of precordial electrocardiogram leads; (b) a pair of aVL and aVR electrocardiogram leads; and (c) an aVF electrocardiogram lead; wherein the glove records a 12-lead electrocardiogram by pressing the glove against skin of a user.

Abstract: Nanomaterial epidermal sensors can be adhered to the skin and worn comfortably and inconspicuously for days to allow for repeated biometric sensing. The nanomaterial epidermal sensors may be comprised of a monolayer of graphene coating a flexible polymer substrate. Various nanomaterial epidermal sensors may be quickly fabricated using a cost-efficient “cut-and-paste” method on transfer paper and can be adhered directly to skin without tape or adhesive, much like a temporary-tattoo. The nanomaterial epidermal sensors may be optically transparent and may be used to measure an electrocardiogram (ECG), an electroencephalogram (EEG) or an electromyogram (EMG) with a signal-to-noise ratio that is comparable to conventional electrodes. In addition, the nanomaterial epidermal sensors may be used to measure other parameters, such as skin temperature or skin hydration.

Abstract: Methods and systems for sensor calibration and sensor glucose (SG) fusion are used advantageously to improve the accuracy and reliability of orthogonally redundant glucose sensor devices, which may include optical and electrochemical glucose sensors. Calibration for both sensors may be achieved via fixed-offset and/or dynamic regression methodologies, depending, e.g., on sensor stability and Isig-Ratio pair correlation. For SG fusion, respective integrity checks may be performed for SG values from the optical and electrochemical sensors, and the SG values calibrated if the integrity checks are passed. Integrity checks may include checking for sensitivity loss, noise, and drift. If the integrity checks are failed, in-line sensor mapping between the electrochemical and optical sensors may be performed prior to calibration.

Abstract: A sensor (e.g., an optical sensor) that may be implanted within a living animal (e.g., a human) and may be used to measure an analyte (e.g., glucose or oxygen) in a medium (e.g., interstitial fluid, blood, or intraperitoneal fluid) within the animal. The sensor may include a sensor substrate, electrode or housing, an analyte indicator covering at least a portion of the sensor, and one or more compounds that reduce degradation of the analyte indicator.

Abstract: A device and method for noninvasively monitoring biofluids of an animal provides measuring physical parameters of an analyte with a device located within an oral cavity of the animal.

Abstract: A light source device includes: a laser light source configured to emit laser light having a peak wavelength included in a wavelength range of light absorbed or reflected by a first region or a second region of an object under study, the laser light source being configured to form a speckle pattern having speckle contrasts that differ between the first region and the second region; and a speckle variable device configured to control a coherence of the laser light in response to an external control signal.

Abstract: The invention relates to mental health and using technology that can analyze and interpret hormones from drops of sweat and also a peer to peer feedback system to predict mental health issues (such as depression) in an individual. The invention further relates to the monitoring of sweat and feedback and interpreting the two in tandem to identify symptoms of mental health illnesses in an individual over a period of time (to predict and prevent that certain mental health disease). Furthermore, the records of the sweat analysis and peer to peer feedback will be utilized to provide smart suggestions and track the mental health of an individual.

Abstract: A noninvasive physiological sensor for measuring one or more physiological parameters of a medical patient can include a bump interposed between a light source and a photodetector. The bump can be placed in contact with body tissue of a patient and thereby reduce a thickness of the body tissue. As a result, an optical pathlength between the light source and the photodetector can be reduced. In addition, the sensor can include a heat sink that can direct heat away from the light source. Moreover, the sensor can include shielding in the optical path between the light source and the photodetector. The shielding can reduce noise received by the photodetector.

Abstract: A non-invasive blood glucose detection device and a measurement method based on a multi-technology integration is provided according to the disclosure. The device combines a near-infrared spectroscopy non-invasive blood glucose detection technology with a non-invasive blood glucose detection technology based on optical polarimetry, thus improving the detection sensitivity and accuracy, simultaneously inhibiting the influence of human background and individual differences. The AOTF can be used to achieve tunable light splitting and the output lights have two orthogonal linearly polarized light characteristics. The hardware for implementing the two methods are combined. Thus, the device has the advantages of simple structure, strong anti-interference ability and low cost. In addition, it combines the two methods on software by adopting a random forest algorithm and a data fusion algorithm, which effectively improves the prediction accuracy of non-invasive blood glucose concentration.

Abstract: A system with a saliva sampling device configured to be orally worn by a patient. The saliva sampling device is a polymer retainer or aligner. A saliva analysis engine is used to correlate one or more analytes of one or more saliva samples with one or more health attributes. A health monitoring engine updates a health profile of the patient based on the correlated health attributes.

Abstract: Computer implemented methods, systems and devices are provided to monitor for potential heart failure (HF). Cardiac activity (CA) data is obtained and filtered to obtain respiration data indicative of a respiration pattern. The respiration data is analyzed to determine one or more respiration characteristics of interest (COI) that are recorded along with collection time information to form an HF monitoring log. Additionally or alternatively, the CA data is analyzed to detect an event of interest. The cardiac activity data is filtered to obtain respiration data indicative of a respiration pattern, and the respiration data is analyzed for respiration induced under detection of the event of interest from the CA data.

Abstract: A regional oximetry pod drives optical emitters on regional oximetry sensors and receives the corresponding detector signals in response. The sensor pod has a dual sensor connector configured to physically attach and electrically connect one or two regional oximetry sensors. The pod housing has a first housing end and a second housing end. The dual sensor connector is disposed proximate the first housing end. The housing at least partially encloses the dual sensor connector. A monitor connector is disposed proximate a second housing end. An analog board is disposed within the pod housing and is in communications with the dual sensor connector. A digital board is disposed within the pod housing in communications with the monitor connector.