Abstract: A method for treatment and prevention of neonatal hyperbilirubinemia by oral administration of a preparation to treat and prevent neonatal hyperbilirubinemia. A preparation that can be used includes castor oil, honey and cellulose fibers. Another preparation that can be used includes castor oil, cellulose fibers, magnesium and vitamin B.sub.2. The magnesium may be in the form of magnesium salts, magnesium oxides or any other form suitable for use in newborns.

Abstract: A method is provided for reducing the duration of diarrhea and recurrent episodes of diarrhea in humans by enterally administering indigestible oligosaccharides prophylactically. More specifically, the present invention relates to a method using indigestible oligosaccharides or fructooligosaccharides (FOS) to reduce the duration and recurrence of diarrhea in a human wherein between 0.5 grams and 5 grams of at least one FOS selected from the group consisting of 1-kestose, nystose, and 1.sup.F -.beta.-fructofuranosyl nystose is administered to said human per day. The indigestible oligosaccharides can be produced through enzymatic synthesis, chemical techniques or isolated from plant materials and are administered in the form of a nutritional product, candy, tablets, chewing gum, lozenges, milk, yogurts, fermented products and the like.

Abstract: A stabilized cosmetic or dermatological active composition containing a vehicle comprising not more than 10% by weight of water, at least one amphiphilic oil, at least one polyol or polyol derivative selected from the group consisting of C.sub.2 -C.sub.4 glycols, ether derivatives of a C.sub.2 -C.sub.4 glycol and mixtures thereof, and at least one solvent for oil and water, containing an alcohol functional group.

Abstract: There is provided a skin lotion composition with non-greasy skin feel, capable of being stably encapsulated within a softgel, and which may preferably include tocopheryl acetate and/or vitamin A palmitate and methods for making and using the same.

Abstract: The present invention relates to compositions comprising flubendazole of formula (I), which are palatable to companion animals, especially dogs. ##STR1## These find utility as palatable anthelmintic compositions for the treatment of helminthiasis.

Abstract: The present invention relates to 1) pharmaceutical compositions and methods for chemotherapeutic agents and 2) pharmaceutical compositions for biological agents, particularly those whose target cells or tissues are resistant to the biological agent. The invention is targeted to overcome the resistance to biological agents that are developed by neoplasms and microbial infections. The formulation contains a biological agent and a polyether block copolymer. The block copolymer comprises an A-type linear polymeric segment joined at one end to a B-type linear polymeric segment; wherein the A type polymeric segment is hydrophilic, has repeating units which contribute an average Hansch-Leo fragmental constant of about 0.4 or less, and has a molecular weight contribution between 30 to about 500. The B-type segment is of relatively hydrophobic character, has repeating units which contribute an average Hansch-Leo fragmental constant of about -0.

Abstract: Paraffin oil and lactulose-based jellied clear laxative emulsion containing from 75 to 85 parts by weight of liquid paraffin oil and from 25 to 15 parts by weight of an edulcorated lactulose aqueous solution. The invention also concerns a method for the preparation of said emulsion.

Abstract: The present invention relates to the method and composition for use of diet supplements by athletes and bodybuilders. A first supplement comprising, the amino acid acetyl-L-Carnitine, in conjunction with a series of nutritionally essential branched-chain amino acids, zinc, OKG, taurine, in conjunction with two other independently administered supplements: a fat burning agent and a creatine synthesizer.

Abstract: A process for reversibly applying a cosmetic composition to the skin or comprising: a) contacting the skin or hair with the cosmetic composition, the composition comprising at least one amphiphilic material which is capable of forming a water-insoluble liquid crystal phase of greater than one-dimensional periodicity and a cosmetic agent and b) when desired, removing the cosmetic composition by applying to the skin or hair a cleansing composition comprising a surface active agent and a hydrotrope capable of destroying the liquid crystal phase formed in a step a). An advantage of such a system is that the cosmetic agent is strongly adhered to the skin or hair when applied and can be effectively removed when desired.

Abstract: The present invention relates to the use of a cyclodextrin or a derivative thereof as a mucoadhesive in an emulsion or aqueous solution, said cyclodextrin or derivative thereof being used in an amount from 10% to 70% by weight based on the total weight of the composition.

Abstract: A liquid hair cosmetic composition comprising:(A) From about 0.1% by weight to about 10% by weight (acid basis) of a silicone-containing polycarboxylic acid copolymer having a vinyl polymeric backbone, and having grafted to the backbone a silicone-containing macromer having a weight average molecular weight of from about 1,000 to about 50,000. (B) A neutralizing system consisting essentially of sodium hydroxide present at a lever sufficient to neutralize at least about 25% of the acid groups on the silicone containing copolymer; (C) From about 0%-1.0% by weight of water; and (D) The balance comprising a carrier suitable for application to hair. The liquid hair cosmetic products have improved clarity and storage stability and demonstrate excellent hair styling benefits in addition to hair feel attributes and ease of removal and brush out.

Abstract: An extract from the Centipeda genus is obtained by a successive extraction process using varying concentrations of aqueous-ethanol solvents. The resulting extract is effective in the treatment of various skin disorders including the relief of itching and dry skin from psoriasis. The extract also has antiinflammatory, antiallergetic, sunscreen and cell renewal properties.

Abstract: A method of treating an animal to maintain or enhance the mineral content of the bones of the animal consists of administering to the animal a safe and effective amount of CLA. Compositions for use in the method are also disclosed.

Abstract: Metal oxide-doped colored zinc oxides are useful as colorants and UV absorbers in cosmetics.

Abstract: The present invention relates to a wrinkle reducing composition for use on fabrics, particularly clothing. The composition comprises a wrinkle reducing active, which is made up of an effective amount of silicone and an effective amount of film-forming polymer, and a liquid carrier. The composition is substantially free of starch, modified starch, and mixtures thereof, and results a Loss Modulus Difference of greater than about 3.3.times.10.sup.7 Pascal on fabric. The composition can be incorporated into a spray dispenser that can create an article of manufacture which facilitates treatment of the fabric with the wrinkle reducing composition. The wrinkle reducing actives in the composition can be determined through Dynamic Mechanical Analysis using a 100% cotton broadcloth swatch and a fixed volume of a sample of wrinkle reducing active.

Abstract: An external skin treatment composition comprising (a) vitamin A and (b) (i) at least one kind of powder or (ii) at least one silicone oil selected from the group consisting of dimethyl polysiloxane and methylphenyl polysiloxane having a viscosity of 2-20 cs at 25.degree. C.

Abstract: A vehicle useful for delivery of capsaicin that is convenient, and acceptable to patients, and which insures sufficient exposure to the capsaicin to produce desensitization is the subject of this invention. The applicants have developed a candy vehicle for the delivery of capsaicin. Candies containing 5-9 ppm capsaicin were made by adding cayenne pepper to a standard candy carrier recipes.

Abstract: An injectable ivermectin composition having a programmable release rate and providing multiple concentration peaks of active ivermectin to produce a sequence of ivermectin release pulses into the blood of cattle and horses. The composition comprises a solution of 0.2%-10% w/w of ivermectin in a solvent selected from propyleneglycol and a mixture of glycerile caprylate, caproate and caprate, such as glycerides of caproic, caprilic and capric acids in equal parts. The solution is used as a vehicle for suspending microspheres 100 nm-200 .mu.m in diameter of a degradable polymer containing between 0.5% and 50% of ivermectin. The microspheres may be formed from polylactic acid, polyglycolic acid or a copolymer of polylactic-polyglycolic acid. The programmable multi-pulse release system may also be obtained with a biodegradable matrix selected from hardenable natural polymers, such as gelatin or albumin, apart from the copolymers of lactic and gycolic acids.

Abstract: A composition having equal to or greater than about 97 percent by weight phosphatidylcholine and about equal to or less than about 3 percent by weight to about 0.5% sphingomylin and equal to or less than about 0.5% lysophosphatidylcholine (undetectable by UV at 205 nm) has been found to result in liposomes having improved stability. Methods for preparing the composition are disclosed whereby the phospholipids are extracted and then purified using silica chromatography.

Abstract: A cosmetic or dermatological composition containing a mixture of at least one type-III ceramide in the form of a single stereoisomer and of at least one type-V ceramide. This mixture is in particular a mixture having a melting point which is much lower than that of the type-III ceramide. This composition is intended in particular for moisturizing dry skins.