Abstract: Mineral-based composition and methods of use thereof in preventing skin damages, such as in subjects exposed to radiation, are provided.

Abstract: The present invention relates to a modified release pharmaceutical formulation comprising one or more sustained release granules that may be prepared by over-mixing and hot melt granulation. The invention also relates to disintegrating monolithic modified release tablets comprising the sustained release granules as an internal phase and an immediate release formulation of a drug or drugs as an external phase. The drug release profile from either these granules or these tables may be adjusted by adjusting the percentages of the formulation's components. In one application, the disintegrating monolithic modified release tablets comprise amoxicillin and clavulanate and have a dissolution profile similar to brand and generic “Augmentin XR® Bilayered Extended Release Tablets (1000 mg/62.5 mg)”. The invention also relates to a method of preparing the foregoing sustained release granules.

Abstract: The subject matter of the invention is a carrier loaded with bioactive substances, wherein the carrier is carbonate substituted hydroxyapatite and the bioactive substances are an ion and a plant extract, wherein the ion is selected from the group consisting of Cu, Zn and a combination thereof, and wherein the plant extract consists of mint extract, rosemary extract, Ocimum basilicum extract, lemon extract, garlic extract, clove extract, thyme extract and cinnamon extract.

Abstract: The invention relates to a cosmetic composition, in particular in the form of a liquid cosmetic composition, comprising in a physiological medium (i) at least a plate type filler with refractive index>1.6 and having a particle size between 1 ?m and 20 ?m, preferably between 1 ?m and 15 ?m, (ii) at least a silicon elastomer, preferably a non-emulsifying silicon elastomer, and (iii) at least a filler having an oil absorption capacity greater than or equal to 1 ml/g. The composition is preferably used as a skin care or make-up base or primer intended to decrease the visibility of skin imperfections, in particular the pores and make the pore hiding effect long lasting.

Abstract: Described herein is a hair conditioner composition and methods of using the same, the hair conditioner composition including an effective chelant. The hair conditioner composition further includes one or more high melting point fatty compounds and a cationic surfactant.

Abstract: A multilayer flexible film for packaging a transdermal patch product comprising a pharmaceutical active agent comprises: a product-contacting sealing layer comprising a co-polyester having a surface energy of at least 50 dyne/cm2; and one or more layers above the product-contacting sealing layer. The pharmaceutical active agent may comprise nicotine. An average adhesion force to peel the transdermal patch from the product-contacting sealing layer may be less than 100 g/inch (39.37 g/cm).

Abstract: The present invention relates to a permanent shaping composition for the permanent deformation of hair comprising, in a cosmetically acceptable carrier, at least one reducing agent comprising a mercapto functional group, at least one alkalizing agent, and a malodor suppressant system comprising at least a first malodor suppressant, herein the first malodor suppressant has a molecular weight of from 100 to 400 g/mol, and wherein the malodor suppressant system has a distribution coefficient log P (octanol/water) of 2 or more.

Abstract: The present invention relates to a process for the elongation and/or densification of fibers, on a keratin material, characterized in that it employs a composition, especially a cosmetic composition, in particular a makeup composition, comprising at least: —one volatile hydrocarbon-based oil, —particles of at least one polymer surface-stabilized with a stabilizer, and —a hydrophobic film-forming polymer, chosen from hydrocarbon-based block copolymers, hydrocarbon-based resins, and mixtures thereof.

Abstract: A cosmetic ink includes a colorant, a higher alcohol having 3 or more carbon atoms, purified water, an acrylic-based resin, and a film-forming agent. The colorant includes a white-based pigment, a yellow-based pigment, a red-based pigment, and a blue-based pigment. In a coating film of the cosmetic ink, a spectral reflectance curve obtained by measuring spectral reflectances in wavelengths of 400 nm to 700 nm has a first inflection point in a wavelength region of 550 nm or more and 610 nm or less, and a second inflection point in a wavelength region of less than 550 nm; a spectral reflectance at the first inflection point is higher than a spectral reflectance at the second inflection point; and spectral reflectances throughout a wavelength region of more than 580 nm are equal to or higher than a spectral reflectance at a wavelength of 580 nm.

Abstract: The present invention teaches a hair straightening system including formulations that will safely and effectively straighten curly hair for at least 2-3 months after a single application, despite frequent washings of the hair. Methods for obtaining said formulations are disclosed. Hair straightening systems including shampoo and one or more conditioners are also provided.

Abstract: A system and method of preserving cadaveric tissue is provided. The present invention utilizes a preservation fluid having high-dose DMSO, high-dose acetic acid, and isopropyl alcohol. It is believed that the high-dose DMSO serves as a hardening agent while the high-dose acetic acid serves as a softening agent.

Abstract: The present specification discloses compositions comprising one or more encapsulates comprising one or more agents and methods and uses for the disclosed agents. A composition disclosed herein can be incorporated into a body wash, an after shower body lotion, a shampoo, a conditioner, a soap, a gel, a hand sanitizer, a cream, a spray, a mouse, a lotion, an ointment, a make-up product, a lip balm, a hair spray product, an arachnid/insect repellent or a medicinal product.

Abstract: A sunscreen composition comprised of one or more sunscreen active agents encapsulated in a cellulose derived capsule wherein the composition can contain one or more additional agents. A sunscreen composition can be mixed with a bodywash, shampoo, conditioner, lotion, gel, soap, cream, hand sanitizer, spray or mousse and can be used by an individual during their normal hygiene processes, such as during a shower or bath or while applying a body product to their skin or hair.

Abstract: A non-irritation, non-blurring, photostable ophthalmic sunscreen composition contains at least one of the following: bemotrizinol; bisoctrizole; tris-biphenyl triazine; and/or octyl methoxycinnamate. A liquid vehicle base is then a remainder of the solution by weight. The composition is an artificial tear formulation or an ophthalmic suspension or ointment. The composition may include at least one inorganic and/or at least one organic active ingredient. The inorganic active ingredients may include, but not be limited to zinc oxide, titanium dioxide, iron oxide, zirconium oxide, and cerium oxide. The organic active ingredients may include, but not be limited to dioxybenzone, octinoxate, octisalate, homosalate, avobenzone, octocrylene, para-aminobenzoic acid, cinoxate, methyl anthranilate, octocrylene, padimate O, ensulizole, sulisobenzone, trolamine salicylate, and ecamsule.

Abstract: A gradient mineralized cancellous bone matrix material and a preparation method thereof are provided, and the preparation method includes: processing naturally-derived bone tissue with an immunogenicity removal treatment for decellularization, and processing an obtained decellularzed bone with a gradient demineralization treatment to obtain the gradient mineralized cancellous bone matrix material. The present invention expands a porosity of the bone matrix material and a collagen exposure degree on a surface thereof, which effectively releases growth factors and improves adhesion of the material to the cells, so as to up-regulate genes and proteins related to cell regeneration.

Abstract: The invention relates to the process for producing an microemulsion system of nano essential oil, the process comprising the following steps: (i) preparing a dispersed phase of essential oil; (ii) preparing of a carrier formed from a mixture of diethylene glycol monoethyl ether and lecithin; (iii) adding the carrier to the dispersed phase while keeping the dispersed phase temperature between 60 and 100° C. after addition of the carrier, while simultaneously stirring under vacuum; then pass the entire solution mixture through the system of high-pressure homogeneous machine integrated dispersion nozzle; (iv) adding the solution mixture obtained in step (iii) to Capryol 90 while keeping the mixture temperature between 60 and 100° C., and stirring at a rate ranging from 400 up to 800 rpm under vacuum; (v) cooling the mixture, homogenizing the mixture by ultrasonication to achieve a droplet size smaller than 100 nm.

Abstract: A hair care composition is disclosed comprising a cationically modified guar polymer having a cationic degree of substitution of from 0.35 to 0.70, an ethoxylated alkyl sulfate anionic surfactant having a formula RO(CH2CH2O)nSO3M, wherein R is an alkyl or alkenyl group having from 8 to 18 carbon atoms; M is a solubilising cation comprising sodium, potassium, 5 ammonium, substituted ammonium or mixtures thereof; n is the degree of ethoxylation of from 0.5 to 3 and from 0.01 to 10% by weight of an anti-dandruff agent selected from azole based anti-fungal agents, piroctone olamine, metal pyrithione salts, selenium sulfide or mixtures thereof; wherein the degree of substitution is measured using 1H NMR and the spectrum is recorded at 25° C.

Abstract: The present invention relates to cosmetic anti-blemish compositions, in the form of a serum, which are particularly useful in treatments for restoring facial firmness and elasticity (loss of tone).

Abstract: The present invention provides a medical device containing a cake composition comprising aripiprazole as an active ingredient and capable of suppressing agglomeration of aripiprazole in a suspension obtained by resuspending a freeze-dried substance; and a cake composition comprising aripiprazole as an active ingredient. The present invention relates to a medical device containing, in a storage container whose inner wall is treated with silicone, a freeze-dried cake composition comprising separately prepared aripiprazole as an active ingredient, wherein there is a space between the inner wall and the cake composition; and a cake composition comprising aripiprazole as an active ingredient and having a strength of 5 to 100 N.

Abstract: A method for applying a cosmetic composition to skin is disclosed. The method can include applying a first composition to skin that includes at least about 50% by weight of a volatile hydrocarbon, a film former, a solvent comprising an ester group, and a combination of ultraviolet A (UVA) and ultraviolet B (UVB) sunscreen agents, wherein the UVA sunscreen agent comprises 4-tert-butyl-4?-methoxydibenzoylmethane, wherein the first composition has an SPF of at least about 15 and a PFA of at least about 5, and wherein the first composition dries within two minutes after topical application to skin, and subsequently applying the cosmetic composition onto the first composition.