Patents Examined by Dolph H. Torrence
  • Patent number: 4670464
    Abstract: A process for the relative enrichment of a solution of .alpha.-cyano-4-fluoro-3-phenoxybenzyl 3-(Z-2-chloro-3,3,3-trifluoroprop-1-en-1-yl)-2,2-dimethylcyclopropane carboxylate with respect to the enantiomeric pair of isomers represented by (S)-.alpha.-cyano-4-fluoro-3-phenoxybenzyl (1R,cis)-3-(Z-2-chloro-3,3,3-trifluoroprop-1-en-1-yl)-2,2-dimethylcyclopro pane carboxylate and (R)-.alpha.-cyano-4-fluoro-3-phenoxybenzyl (1S,cis)-3-(Z-2-chloro-3,3,3-trifluoroprop-1-en-1-yl)-2,2-dimethylcyclopro pane carboxylate which comprises subjecting a solution comprising the enantiomeric pair of isomers (R)-.alpha.-cyano-4-fluoro-3-phenoxybenzyl (1R,cis)-3-(Z-2-chloro-3,3,3-trifluoroprop-1-en-1-yl)-2,2-dimethylcyclopro pane carboxylate and (S)-.alpha.-cyano-4-fluoro-3-phenoxybenzyl (1S,cis)-3-(Z-2-chloro-3,3,3-trifluoroprop-1-en-1-yl)-2,2-dimethylcyclopro pane carboxylate in an organic solvent to the action of a base to effect epimerization.
    Type: Grant
    Filed: June 27, 1985
    Date of Patent: June 2, 1987
    Assignee: Imperial Chemical Industries PLC
    Inventors: Peter Doyle, Alan J. Whittle
  • Patent number: 4666938
    Abstract: A compound of the formula: ##STR1## useful as a fungicidal agent against phytopathogenic fungi, particularly their strains resistant to benzimidazole and thiophanate fungicides and/or cyclic imide fungicides.
    Type: Grant
    Filed: May 24, 1984
    Date of Patent: May 19, 1987
    Assignee: Sumitomo Chemical Company, Limited
    Inventors: Junya Takahashi, Toshiro Kato, Hiroshi Noguchi, Yukio Oguri, Shigeo Yamamoto, Katsuzo Kamoshita
  • Patent number: 4667051
    Abstract: Compounds of the formula I ##STR1## where R is alkyl of 1 to 10, preferably 1 to 4, carbon atoms, X is O or S, Y is hydrogen or nitrophenyl which is unsubstituted or substituted by chlorine, bromine, methoxy or methyl, when n is 1, and is C.sub.2 -C.sub.6 -alkylene when n is 2, and Z is cyano or 2-benzimidazolyl, are prepared by a process in which an iminoether of the formula II ##STR2## is reacted with a compound of the formula III ##STR3## where A.sup..crclbar. is an anion. The compounds prepared according to the invention are useful intermediates, for example for the preparation of diazo components.
    Type: Grant
    Filed: May 27, 1986
    Date of Patent: May 19, 1987
    Assignee: BASF Aktiengesellschaft
    Inventor: Ernst Schefczik
  • Patent number: 4661610
    Abstract: Veratryl cyanide is prepared by chloromethylating veratrol in solution in toluene and then reacting the resulting veratryl chloride with from 1 to 5 moles of an alkali metal cyanide, by a process in which the toluene from the chloromethylation is not removed for the reaction with cyanide, and from 3 to 25% by weight, based on veratryl chloride, of water, from 5 to 50% by weight, based on toluene, of a ketone of 3 to 6 carbon atoms and from 0.1 to 10% by weight, based on veratryl chloride, of a phase transfer catalyst are added before the reaction with cyanide.
    Type: Grant
    Filed: July 22, 1986
    Date of Patent: April 28, 1987
    Assignee: BASF Aktiengesellschaft
    Inventors: Josef Muller, Walter-Wielant Wiersdorff, Wolfram Burst, Heinz Dralle, Ernst Schaffner, Rolf Steinkamp
  • Patent number: 4659371
    Abstract: A trifluoromethanesulfonanilide compound having the formula: ##STR1## wherein each of R.sup.1 and R.sup.2 is a lower alkyl group, X is a halogen atom or a trifluoromethyl group, n is an integer of 0 to 2, and R.sup.1 and R.sup.2 may form, together with the adjacent carbon atom, a ring which may be substituted by a lower alkyl group.
    Type: Grant
    Filed: June 9, 1986
    Date of Patent: April 21, 1987
    Assignees: Kumiai Chemical Industry Co., Ltd., Ihara Chemical Industry Co., Ltd.
    Inventors: Tetsuo Takematsu, Makoto Konnai, Kuniaki Shimizu, Ikumi Urushibata, Ikuo Kajiwara
  • Patent number: 4659845
    Abstract: Process for the production of N-methylcarbamates: ##STR1## (wherein RO- is the radical of a substituted phenol or of a naphthol), wherein:in a first reaction step methylamine and diphenyl carbonate are reacted with each other, operating in the liquid phase and as a continuous process, in order to form phenol and phenyl-N-methylurethane;in a second reaction step phenyl-N-methylurethane, within the related reaction mixture outcoming from the first step, is thermally continuously decomposed, to yield a gaseous stream containing methyl isocyanate, from which the components different than methyl isocyanate are condensed off;in a third step the methyl isocyanate stream, outcoming from the second step, after an optional preliminary condensation, is continuously fed and contacted with a solution of a substituted phenol or of a naphthol in an inert organic solvent, containing a basic catalyst, to form N-methylcarbamate (I);N-methylcarbamate (I) is finally recovered from the reaction mixture outcoming from the third st
    Type: Grant
    Filed: May 7, 1985
    Date of Patent: April 21, 1987
    Assignee: Enichem Sintesi S.p.A.
    Inventors: Franco Rivetti, Franco Mizia, Guido Garone, Ugo Romano
  • Patent number: 4658051
    Abstract: The present invention relates to novel organocyanohydroborate compounds which may be employed as reducing agents. For example, organocyanohydroborates having the following general formula are contemplated:M.sup.+ BH.sub.3 CR.sub.1 R.sub.2 CN.sup.-In this formula, R.sub.1 and R.sub.2 may be, for example, H, CH.sub.3, or C.sub.6 H.sub.5, or may be represented jointly, for example by C.sub.5 H.sub.10, while M.sup.+ is a cation wh ich is capable of forming a slat. The organocyanohydroborate compounds of the present invention include a --CR.sub.1 R.sub.2 -- moiety between the BH.sub.3 moiety and CN moiety to provide a new class of hydroborate reducing agents.
    Type: Grant
    Filed: April 9, 1985
    Date of Patent: April 14, 1987
    Assignee: Utah State University Foundation
    Inventors: Karen W. Morse, John L. Peters
  • Patent number: 4656295
    Abstract: A process for isolating macrocyclic polyethers from open-chained polyglycols in a mixture by extraction with saturated hydrocarbons in the presence of at least 10 percent by weight ethylene glycol based on the weight of the mixture of macrocyclic polyethers and open-chained polyglycols.
    Type: Grant
    Filed: June 6, 1985
    Date of Patent: April 7, 1987
    Assignee: Consortium fur Elektrochemische Industrie GmbH
    Inventor: Norbert Gamon
  • Patent number: 4656294
    Abstract: A process for producing a polyglycidyl ether which comprises reacting a mixture of 4-oxy-3-methoxybenzaldehyde and 4-oxybenzaldehyde in the molar ratio of 5/95 to 95/5 with pentaerythritol to give a bisphenol having a spiroacetal ring, and further reacting the bisphenol with epihalohydrin or .beta.-methylepihalohydrin is disclosed. The polyglycidyl ether obtained has excellent solubility in solvents, and the cured product obtained therefrom has excellent elongation, modulus of elasticity, impact resistance, and heat resistance.
    Type: Grant
    Filed: July 13, 1984
    Date of Patent: April 7, 1987
    Assignee: Mitsubishi Petrochemical Co., Ltd.
    Inventor: Kaoru Kanayama
  • Patent number: 4654072
    Abstract: Compounds having the formula ##STR1## in which R is hydrogen, cyano or --COOR.sub.2 ; R.sub.1 is hydrogen or C.sub.1 -C.sub.4 alkyl; R.sub.2 is hydrogen or C.sub.1 -C.sub.4 alkyl; and Z is ##STR2## in which A is halogen, B is halogen or hydrogen and Y is nitrogen or --CH--, are herbicides.
    Type: Grant
    Filed: September 17, 1985
    Date of Patent: March 31, 1987
    Assignee: Stauffer Chemical Company
    Inventor: Raymond A. Felix
  • Patent number: 4652584
    Abstract: Phenoxypropanol derivatives having a 2-acetylenic moiety on the phenyl group thereof of the following formula (I): ##STR1## and their use as anti-hypertensives, e.g. in man. Also part of the invention are pharmaceutical compositions and intermediates used in the synthesis.
    Type: Grant
    Filed: July 13, 1984
    Date of Patent: March 24, 1987
    Assignee: McNeilab, Inc.
    Inventor: John R. Carson
  • Patent number: 4652668
    Abstract: A compound having the formula: ##STR1## wherein n is 0-5, inclusive; R.sub.1 is H or the identifying group of an amino acid; and R.sub.2 is H, aralkyl, or alkyl.
    Type: Grant
    Filed: July 3, 1985
    Date of Patent: March 24, 1987
    Assignee: Biomeasure, Inc.
    Inventor: Sun H. Kim
  • Patent number: 4652556
    Abstract: Compounds of the formula: ##STR1## wherein R is aryl of 6 to 12 carbon atoms or aralkyl of 7 to 14 carbon atoms either optionally substituted with 1 to 3 substituents independently selected from lower alkyl of 1 to 6 carbon atoms, lower alkoxy of 1 to 6 carbon atoms, lower alkylthio of 1 to 6 carbon atoms, lower alkylsulfinyl of 1 to 6 carbon atoms, lower alkylsulfonyl of 1 to 6 carbon atoms, halogen, trihalomethyl, nitro, cyano or carboxyl; alkyl of 1 to 10 carbon atoms, cycloalkyl of 3 to 10 carbon atoms, lower alkenyl of 2 to 6 carbon atoms, or lower alkynyl of 2 to 6 carbon atoms, all optionally substituted with 1 to 3 halogen atoms; lower alkoxyalkylene; lower alkylene carbalkoxy; lower alkylthioalkylene; lower alkylsulfinylalkylene; or lower alkylsulfonylalkylene; R.sup.1 and R.sup.2 are independently hydrogen, lower alkyl of 1 to 6 carbon atoms, aryl of 6 to 12 carbon atoms, or thienyl, or taken together form an alkylene bridge to give a cycloalkyl group of 3 to 10 carbon atoms; and R.sup.
    Type: Grant
    Filed: August 19, 1985
    Date of Patent: March 24, 1987
    Assignee: Chevron Research Company
    Inventors: Joseph E. Moore, Yuh-Lin Yang, Robert K. Griffith, David C. K. Chan
  • Patent number: 4650884
    Abstract: The present invention relates to the novel compound of the following formula: ##STR1## as well as acid addition salts thereof, a method for the preparation of the compound of Formula I, and to the use of said novel compound in the preparation of the known antidepressant drug 1-(3-dimethylaminopropyl)-1-(4'-fluorophenyl)-1,3-dihydroisobenzofuran-5-c arbonitrile, or a pharmaceutically acceptable acid addition salt thereof.
    Type: Grant
    Filed: August 2, 1985
    Date of Patent: March 17, 1987
    Assignee: H. Lundbeck A/S
    Inventor: Klaus P. Bogeso
  • Patent number: 4650899
    Abstract: A liquid composition comprising a mixture of isomers of essentially diisocyanates having the diphenylmethane structure, the distribution by weight of isomers in the composition for each 100 parts by weight of the composition being:32 to 55% of the 4,4' isomer,30 to 45% of the 2,4' isomer,5 to 12% of the 3,4' isomer,4 to 10% of the 2,2' isomer, and2 to 5% of the 2,3' isomer;and the method of making the composition by first reacting a benzyl halide with benzene, followed by nitration, hydrogenation, and phosgenation.
    Type: Grant
    Filed: April 26, 1984
    Date of Patent: March 17, 1987
    Assignee: Atochem
    Inventors: Jacques Kervennal, Henri Mathais, Raymond Commandeur
  • Patent number: 4649206
    Abstract: This invention relates to a lignan compound having antioxidative characteristics, an antioxidant having this lignan compound as active component, and antioxidants having as active component a product which contains this lignan compound and is obtained by causing .beta.-glucosidase to react with crushed sesame seeds or a solvent extract thereof.
    Type: Grant
    Filed: September 3, 1985
    Date of Patent: March 10, 1987
    Assignee: Takemoto Yushi Kabushiki Kaisha
    Inventors: Mitsuo Namiki, Toshihiko Osawa, Yasuko Fukuda, Tatsuhiko Ozaki
  • Patent number: 4647582
    Abstract: A compound of the formula: ##STR1## useful as a fungicidal agent against phytopathogenic fungi, and particularly against strains resistant to benzimidazole, thiophanate and/or cyclic imide fungicides.
    Type: Grant
    Filed: December 23, 1983
    Date of Patent: March 3, 1987
    Assignee: Sumitomo Chemical Company, Limited
    Inventors: Junya Takahashi, Toshiro Kato, Hiroshi Noguchi, Yukio Oguri, Shigeo Yamamoto, Katsuzo Kamoshita
  • Patent number: 4647584
    Abstract: A compound of the formula: ##STR1## useful as a fungicidal agent against phytopathogenic fungi, and particularly against strains resistant to benzimidazole, thiophanate and/or cyclic imide fungicides.
    Type: Grant
    Filed: December 28, 1983
    Date of Patent: March 3, 1987
    Assignee: Sumitomo Chemical Company, Limited
    Inventors: Junya Takahashi, Toshiro Kato, Hiroshi Noguchi, Yukio Oguri, Shigeo Yamamoto, Katsuzo Kamoshita
  • Patent number: 4647583
    Abstract: A compound of the formula: ##STR1## useful as a fungicidal agent against phytopathogenic fungi, and particularly against strains resistant to benzimidazole, thiophanate and/or cyclic imide fungicides.
    Type: Grant
    Filed: April 15, 1983
    Date of Patent: March 3, 1987
    Assignee: Sumitomo Chemical Company, Limited
    Inventors: Junya Takahashi, Toshiro Kato, Hiroshi Noguchi, Yukio Ishiguri, Shigeo Yamamoto, Katsuzo Kamoshita
  • Patent number: 4638078
    Abstract: The invention is a compound which comprises an amido alkenoic acid or a water-soluble salt thereof and and arylcyclobutene moiety, wherein the cyclobutene moiety is fused to the aryl radical, and wherein the amide nitrogen is connected to the aryl radical of the arylcyclobutenyl moiety by a direct bond or a bridging member.
    Type: Grant
    Filed: April 25, 1985
    Date of Patent: January 20, 1987
    Assignee: The Dow Chemical Company
    Inventor: Robert A. Kirchhoff