Abstract: Disclosed are pharmaceutical compositions containing naphthoic acid derivatives and method of use for enhancing oxygen availability to mammailian tissue.
Type:
Grant
Filed:
May 11, 1989
Date of Patent:
August 14, 1990
Assignee:
Rorer Pharmaceutical Corporation
Inventors:
John T. Suh, Robert G. Pendleton, Charles E. Pendley, II, Kin T. Yu, Paul R. Menard, Alain B. Schreiber
Abstract: The use of compositions containing bis- or oligo-bis-guanides, alcohols, hydrogen peroxide, carboxylic acids, and water, applied externally, provides for the effective control of eggs of the threadworm Enterobius vermicularis on the skin.
Abstract: Novel 4-[(meth)acrylamidomethyl]-pyrazoles and -isoxazoles of the general formula ##STR1## where R is hydrogen or methyl, R.sup.1 is hydrogen, methyl or ethyl, R.sup.2 and R.sup.3 may be identical or different and are each alkyl of 1 to 6 carbon atoms or unsubstituted or substituted aryl of 6 to 20 carbon atoms, and X is oxygen or an NR.sup.4 group where R.sup.4 is hydrogen or a radical having the meanings of R.sup.2 or R.sup.3, a process for their preparation, and the use of these compounds in particular for polymerization and the preparation of homopolymers and copolymers, are described.
Type:
Grant
Filed:
June 2, 1989
Date of Patent:
July 3, 1990
Assignee:
BASF Aktiengesellschaft
Inventors:
Kaspar Bott, Bernhard Nick, Guenther Schulz
Abstract: This invention relates to a process for resolving (.+-.)-cis-1-ethyl-1,3,4,9-tetrahydro-4-(phenylmethyl)pyrano[3,4-b]indole- 1-acetic acid (pemedolac) usinig brucine to obtain the corresponding (1S,4R)-eutomer. Said eutomer is useful as an analgesic.
Abstract: The invention relates to rhodium complexes of the formula[A--O--(CH.sub.2 CH.sub.2 O).sub.n --A].sup.2+ 2 X.sup.- Iaand[A--O--(CH.sub.2 CH.sub.2 O).sub.m --CH.sub.3 ].sup.+ X.sup.-Ibin whichn=5-1,000,m=5-250,X.sup.- denotes a tetrafluoroborate, hexafluorophosphate or per-chlorate anion,A denotes a radical of the formula ##STR1## (en).sub.2 denotes two molecules of a monoolefin or one molecule of a diolefinAr denotes phenyl or phenyl which is substituted by one or two alkyl groups having 1 or 2 carbon atoms andR.sup.1 denotes an arylene or alkylene bridge, and their use for the preparation of L-phosphinothricin and its derivatives by enantioselective catalytic hydrogenation of 2,3-dehydrophosphinothricin (derivatives).