Abstract: Provided herein is a clamp device that can be used in minimally invasive procedures, including surgeries such as laparoscopic surgeries, for clamping a tissue or an organ or a portion of a tissue or organ. Also provided herein are methods of clamping a tissue or an organ or a portion thereof during minimally invasive surgery using the clamp device provided herein. Also provided are systems for performing a minimally invasive surgery that include the clamp device for minimally invasive surgery provided herein and an injection device configured to access an endoscopic port for the minimally invasive surgery.

Abstract: An interventional catheter is adapted for treating a blood vessel. In an embodiment, the catheter includes an elongate shaft sized for insertion in a blood vessel and a stent positioned on a distal region of the elongate shaft. An expandable dilation member is coupled to a distal region of the elongate shaft. The expandable dilation member is adapted to expand outward. A stent containment member is positioned over the elongate shaft and the stent to contain the stent in a collapsed state.

Abstract: Surgical assemblies, instruments, and related methods are disclosed that control tissue gripping force. A method for controlling grip force in a robotic surgical instrument includes actuating an input link of a spring assembly. An actuation force is transferred from the input link to an output link of the spring assembly. Relative movement is inhibited between the input link and the output link when the transferred actuation force is below a predetermined level with a preloaded spring of the spring assembly. The input link is moved relative to the output link by deforming the preloaded spring when the transferred actuation force increases above the predetermined level. A grip mechanism is actuated via the output link.

Abstract: A cerumen removal apparatus for removing cerumen from an ear canal. The apparatus includes a body having a distal end and a proximal end interconnected by a main longitudinal axis; said distal end including a hollow collector head having at least one spiral vane or ridge projecting radially inward from an inner surface thereof and enclosing a lumen ending with an opening opened to said lumen for amassing said cerumen in said lumen via said opening; wherein said at least one spiral vane or ridge is adapted to guide the cerumen in a proximal direction into said hollow collector head when said hollow collector head rotates in the ear canal.

Abstract: A needleless transseptal device assembly, and associated methods, for accessing the left atrium of a human heart includes a tubular body sized to navigate vasculature, and a dilator having a proximal end and a distal end. The dilator is substantially housed and axially movable within the tubular body. The assembly further includes a guidewire that is substantially housed and axially movable within the dilator. The guidewire includes a flexible proximal section and a flexible distal section, and the flexible distal section has a distal end with rotatable, septal tissue cutting elements. The distal end may be configured with a blunt shape. Further, the tubular body and the dilator may be arranged in a steerable configuration. A torquing member may also be coupled to the proximal section of the guidewire to assist in the rotational movement of the septal tissue cutting elements.

Abstract: A device for feeding and setting an implant into a blood vessel includes a hollow cylindrical portion formed of an expandable wire mesh netting with a first end and a second end, with a sleeve for receiving the implant in a radially compressed state. The sleeve is arrangeable along a guide wire. The sleeve for receiving the implant in the radially compressed state is formed by an inner sleeve, around which at least one outer sleeve with a distal end and a proximal end is arranged. The implant is arranged in the inner sleeve in such a way that the second end of the hollow cylindrical portion is arranged on the end facing the proximal end of the outer sleeve, so that during setting of the implant, the inner sleeve surrounding the implant can be moved into the outer sleeve in the distal direction so that the implant expands, beginning from the second end.

Abstract: Devices for removing clot material from a blood vessel lumen and associated systems and methods are disclosed herein. A clot retrieving device may include, for example, an elongated shaft, a capture structure, a cover, and a connector coupled to the distal zone of elongated shaft. The connector may include an inner band and an outer band. The inner band may at least partially surround the distal zone of the elongated shaft and a portion of the proximal region of the capture structure, and the outer band may at least partially surround the inner band. In some embodiments, the first end portion of the cover may be secured between the inner band and the outer band.

Abstract: According to an aspect of the present disclosure, an end effector for use with a surgical device is provided. The end effector includes a drive assembly, a driver, a needle assembly, and a follower. The drive assembly includes a first helical groove. Rotation of the drive assembly in a first direction causes distal translation of the driver with respect to the drive assembly. The needle assembly is disposed in mechanical cooperation with the driver. Distal translation of the driver causes a corresponding distal translation of the needle assembly. The follower is configured to engage the first helical groove of the drive assembly. When the follower is engaged with the first helical groove, rotation of the drive assembly in the first direction causes distal translation of the follower with respect to the drive assembly.

Abstract: Described herein are systems and methods from delivering prosthetic devices, such as prosthetic heart valves, through the body and into the heart for implantation therein. The prosthetic devices delivered with the delivery systems disclosed herein are, for example, radially expandable from a radially compressed state mounted on the delivery system to a radially expanded state for implantation using an inflatable balloon of the delivery system. Exemplary delivery routes through the body and into the heart include transfemoral routes, transapical routes, and transaortic routes, among others.

Abstract: A delivery system is provided for self-expanding medical devices, such as stents. The delivery system has a restraining sheath that maintains the stent in a compressed state prior to deployment. The restraining sheath terminates distally from the deployment handle, and a wire connects the restraining sheath to the deployment handle. The restraining sheath is withdrawn from the stent to deploy the stent by pulling the wires proximally at the deployment handle.

Abstract: A clot encasement and removal device for removing a vascular obstruction is disclosed. The encasement device comprises proximal and distal capture members and a central stabilizer. The central stabilizer provides several points of contact for interacting with and manipulating an intravascular obstruction. The central stabilizer may be coupled to the distal capture member, allowing the central stabilizer and distal capture member to be manipulated in unison. The central stabilizer may reside on a distinct delivery wire, enabling independent control of proximal and distal capture members and the central stabilizer. The proximal capture member may comprise a furrowed delivery wire to enable retraction of at least a portion of the central stabilizer within the proximal capture member.

Abstract: A flexible surgical instrument has structural backbones in crossed arrangement, the flexible surgical instrument includes a flexible continuum structure comprising a distal structure, a proximal structure and a middle connection body; the distal structure includes a first distal segment and a second distal segment, the proximal structure includes a proximal segment; first segment structural backbone(s) on the proximal segment and first segment structural backbone(s) on the first distal segment are fixedly connected respectively one to one or are of the same structural backbone; second segment structural backbone(s) on the proximal segment and second segment structural backbone(s) the second distal segment are fixedly connected respectively one to one or are of the same structural backbone; the middle connection body includes two passage fixing plates, between which structural backbone guiding passage(s) and structural backbone cross guiding passage(s) are fixedly connected; the first segment structural backbo

Abstract: A delivery system for delivering and deploying stents with proximal and distal apices includes a guidewire catheter, a nose cone assembly, a proximal capture portion and a stent graft with proximal and distal stents. The nose cone assembly is at the distal end of the guidewire catheter and includes a nose cone and a distal capture portion. The proximal capture portion is proximal to the distal capture portion of the nose cone assembly. The proximal stent is releasably secured to the distal capture portion and the distal stent is releasably secured to the proximal capture portion. The stent graft can be deployed by releasing the proximal stent and the distal stent from proximal and distal capture portions of the delivery system.

Abstract: A stent delivery system includes a self expanding stent positioned about a distal support segment of a catheter, which includes a proximal segment. A constraint has a wrapped configuration, which has a hollow elongated shape, and an unwrapped configuration, which is a continuous length of a strip. The stent is in contact with, and held in a compressed state by, the constraint in the wrapped configuration, and the stent is in an expanded state out of contact with the constraint in the unwrapped configuration. The constraint may move from the wrapped configuration toward the unwrapped configuration responsive to tension in a control line connected to one end of the strip.

Abstract: A surgical end effector includes a clevis and two jaws rotatably coupled to the clevis. A rocking pin in the form of a solid of revolution is pivotally supported by the clevis. The rocking pin may be pivotally supported by the clevis at the midpoint between the first and second ends. The opposite ends of the rocking pin engage the jaws to constrain the jaws to have opposite motions around the axes of rotation of the jaws. The clevis may be coupled to an elongate shaft to provide an endoscopic instrument. The first and second jaws may be electrically isolated from one another for electrocautery and the rocking pin may be formed from a non-conductive material or electrically isolated from the first and second jaws by electrically non-conductive liners. The jaws may be opened and closed by pushing and pulling on wires coupled to the jaws.

Abstract: An exemplary valve repair device for repairing a native valve of a patient includes: a coaption element; a pair of paddles connected to the coaption element; a first cover extending from a distal end of the device and covering at least a portion of the paddles; and a second cover extending from a proximal end of the device and covering at least a portion of the coaption element. The paddles are movable between an open position and a closed position and are configured to attach to the native valve of the patient.

Abstract: A microdebrider comprising: (a) a handpiece; (b) an interchangeable tip connected to the handpiece; (c) an outer tune rotatably connected to the interchangeable tip, the outer tube including an outer tube window; (d) an inner tube extending at least partially through the outer tube, the inner tube including an inner tube window; (e) a lock selector connected to the inner tube; and (f) a bias device; wherein the bias device is movable, and upon movement of the bias device into contact with the lock selector the inner tube is immobilized so that the inner tube window is aligned with the outer tube window, aligned with a wall of the outer tube, or in a condition therebetween.

Abstract: A hemostatic device is disclosed, which capable of favorably maintaining strength of an inflatable portion and reducing a pressing force acting on a site where bleeding is to be stopped over time to such an extent that vascular occlusion can be prevented without operation by a doctor or a nurse. The hemostatic device includes a band for wrapping around a wrist, a fastener or means for securing the band to the wrist in a wrapped state, and an inflatable portion connected to the band and inflated by being injected with a gas, in which the inflatable portion includes a resin layer made of a resin material, a particulate portion dispersed in the resin layer, and a space portion formed around the particulate portion. The space portion contains gas dispersed in the resin layer so as not to communicate between an inner surface and an outer surface of the resin layer.

Abstract: Soft embolic implants exhibiting secondary shapes are disclosed. Some of the embolic implants exhibit progressively increasing softness from the distal end to the proximal end of the coil. The embolic implants have a primary coil, an optional second coil, a shape wire, and a stretch resistant fiber disposed in the lumen of the primary coil. An optional distal support wire is also disclosed. The embolic implants include a proximal constraint assembly configured to be releaseably retained by a delivery device. Disposed near each end of some of the implants are elliptical hole washers through which the shape wire and the stretch resistant fiber are threaded. The embolic implants have a primary, linear configuration for delivery through an implant tool, and a secondary configuration after deployment from the implant tool. The secondary shape can be J-shaped, helical, spherical, complex, or a combination of shapes.

Abstract: An endoscopic surgical blade is disclosed. The blade is of a hook design, having an upper cutting surface located on the trailing edge of an arm and a lower cutting surface on the upper edge of the main body of the blade. The blade is part of an endoscopic knife assembly which also contains a knife tube and alignment ring. The endoscopic knife assembly is for use in endoscopic surgery by insertion of the assembly through a slotted cannula. The knife tube is hollow and allows the insertion of an endoscope for viewing of the surgical procedure. A method for a performing an operative procedure on a target tissue in a subject using an endoscopic knife assembly having a hook blade is also described.