Abstract: A robotic patient positioning assembly including a patient treatment couch, and a robotic arm coupled to the patient treatment couch. The robotic arm is configured to move the patient treatment couch along five rotational degrees of freedom and one substantially vertical, linear degree of freedom.

Abstract: Described herein are implantable devices configured to emit an electrical pulse. An exemplary implantable device includes an ultrasonic transducer configured to receive ultrasonic waves that power the implantable device and encode a trigger signal; a first electrode and a second electrode configured to be in electrical communication with a tissue and emit an electrical pulse to the tissue in response to the trigger signal; and an integrated circuit comprising an energy storage circuit. Also described are systems that include one or more implantable device and an interrogator configured to operate the one or more implantable devices. Further described is a closed loop system that includes a first device configured to detect a signal, an interrogator configured to emit a trigger signal in response to the detected signal, and an implantable device configured to emit an electrical pulse in response to receiving the trigger signal.

Abstract: In some embodiments, a motion detection and correction system and/or device for tracking and compensating for patient motion during a medical imaging scan can be adapted to be integrated into a medical imaging scanner, such as an MRI scanner, or be adapted to retrofit a pre-existing medical imaging scanner. In certain embodiments, the motion detection system and/or device can comprise one or more mounting brackets and a motion correction device housing, which can further comprise one or more detector modules and a power unit. In further embodiments, the collected motion data can be further analyzed by an image processing unit of the motion tracking and/or correction system.

Abstract: A measurement apparatus includes a housing, a display disposed on the front face of the housing, a contact interface, to be contacted by a test site, disposed on a different surface than the front face of the housing, a laser light source that emits laser light from the contact interface, a light receiver that receives scattered laser light from the test site, a biological information generator that generates biological information based on output from the light receiver, and a controller that controls emission of laser light in the laser light source.

Abstract: Methods, systems, computer-readable media, and apparatuses for obtaining at least one bodily function measurement are presented. A mobile device includes an outer body sized to be portable for user, a processor contained within the outer body, and a plurality of sensors physically coupled to the outer body. The sensors are configured to obtain a first measurement indicative of blood volume and a second measurement indicative of heart electrical activity in response to a user action. A blood pressure measurement is determined based on the first measurement and the second measurement. The sensors also include electrodes where a portion of a user's body positioned between the electrodes completes a circuit and a measurement to provide at least one measure of impedance associated with the user's body. A hydration level measurement is determined based on the measure of impedance.

Abstract: In certain aspects, the invention relates to processes for using renally excretable optical agents to detect one or more tissues of the renal system of a surgical patient. In certain aspects, the invention relates to a kit including a biocompatible composition containing one or more optical agents and instructions for using the optical agent(s) in a process of the present invention.

Abstract: Described herein are implantable devices configured to detect an electrophysiological signal. Certain exemplary implantable devices comprise a first electrode and a second electrode configured to engage a tissue and detect an electrophysiological signal; an integrated circuit comprising a multi-transistor circuit and a modulation circuit configured to modulate a current based on the electrophysiological signal; and an ultrasonic transducer configured to emit an ultrasonic backscatter encoding the electrophysiological signal from the tissue based on the modulated current. Also described herein are systems that include one or more implantable devices and an interrogator comprising one or more ultrasonic transducers configured to transit ultrasonic waves to the one or more implantable devices or receive ultrasonic backscatter from the one or more implantable devices.

Abstract: An apparatus includes a balloon adapted to be placed adjacent a calcified region of a body. The balloon is inflatable with a liquid. The apparatus further includes a shock wave generator within the balloon that produces shock waves that propagate through the liquid for impinging upon the calcified region adjacent the balloon. The shock wave generator includes a plurality of shock wave sources distributed within the balloon.

Abstract: A handheld surgical tool includes a handle, an instrument shaft, and a navigation device, which includes at least one sensor unit for sensing positional data, a computing unit configured to determine a position in space based on signals of the sensor unit, at least one set key and a position memory configured to store a data set for a position upon activation of the at least one set key. A comparator is operatively connected to the position memory for comparing an actual position against a stored position in at least two different operation modes and for generation of a deviation signal, wherein operation modes differ in that a first mode is configured for a reduced comparison only which lacks at least one spatial dimension. A feedback device is provided supplied with the deviation signal and being configured to indicate direction and preferably magnitude of any deviation.

Abstract: An ultrasound device performs an ultrasound scan to acquire a video clip having a plurality of images in a selected zone of a set of lungs. The ultrasound device detects B lines in each of the images of the video clip. The ultrasound device assigns a score to each of the images of the video clip based at least in part on the detected number of B lines. The ultrasound device highlights the detected B lines in each of the images of the video clip. The ultrasound device identifies a representative image from the highlighted images of the video clip in the selected zone. The identification of the representative image is based at least in part on the assigned score of each of the images. The ultrasound device displays the identified representative image.

Abstract: Reception beamforming is executed using delay times that complexly vary in accordance with differences between transmission conditions. An irradiation area 32 of a transmission beam is calculated, and the lengths of segments, using which delay times are calculated, are set in accordance with the positional relationships between the calculated irradiation area 32 and reception scanning lines 31. For example, the reception scanning lines 31 are divided into areas A to C, and the lengths of segments 40b in the outer area B located outside of the irradiation area 32 are set shorter than the lengths of segments 40a and 40c in the inner areas A and C.

Abstract: An ultrasonic processing apparatus includes a viscoelastic coefficient calculation unit that calculates a viscoelastic coefficient of an object from an ultrasonic signal acquired through an oscillator of a probe; and a spatial change amount calculation unit that calculates spatial change amount of the viscoelastic coefficient calculated by the viscoelastic coefficient calculation unit and outputs the calculated spatial change amount as brightness information when displaying an image relating to the viscoelastic coefficient.

Abstract: Systems and a method for reducing periodic artifacts in an electrophysiologic signal are provided. The method includes receiving a time-series electrophysiologic signal acquired from a subject and providing a regression model that defines an interference signal caused by periodic artifacts using a harmonic representation. The method also includes applying the regression model using the time-series electrophysiologic signal to define a cost function and performing an iterative optimization process to estimate regression parameters that minimize the cost function. The method further includes determining, using the regression parameters, the interference signal, and generating a corrected time-series electrophysiologic signal by reducing the interference signal.

Abstract: Shear Wave Dispersion Vibrometry (SDUV) is performed such that, after a single instance of their push pulse (218), a plurality of tracking pulses (222) are issued to sample, more than once, each of a plurality of locations (120, 148) on an associated monochromatic shear wave (116) in sampling that at least one of scans the plural locations in separate passes and, with a pulse of the plural tracking pulses, samples multiple ones of the plural locations concurrently. In a supplementary aspect, phase difference, for a given moment, is determined by taking into account intersample delay (156), if the determination relies on samples that are taken at different times.

Abstract: A surgical instrument for treating tissue during use of a diagnostic scanning device. The surgical instrument includes a housing, an actuating mechanism and an end effector assembly. The actuating mechanism is configured to activate the end effector assembly to treat tissue. At least a portion of the end effector is made of a material that is compatible with the diagnostic scanning device and allows a user to insert and activate the end effector to treat tissue at a surgical site within a patient while the surgical site is monitored during diagnostic scanning device.

Abstract: A self-sealing catheter valve that includes a flexible tubular part having a distal opening and an opposite proximal opening, and a proximal valve part. The proximal valve part has a curved self-sealing flexible diaphragm disposed inside the flexible tubular part and has a base perimeter united with a circumferential wall of the flexible tubular part. The curved self-sealing flexible diaphragm has a concave surface facing towards the proximal opening, and a convex surface facing towards the distal opening, and a flexible diaphragm wall of the curved self-sealing flexible diaphragm has a traverse slit. The self-sealing catheter valve provides an efficient self-closing mechanism for a peripheral catheter assembly and constitutes an efficient barrier against potential contagious spread from the patient to the surrounding environment by blood born disease e.g. HIV, hepatitis and Ebola viruses.

Abstract: Among other things, a user of a browser is exposed simultaneously to three interfaces: A viewing interface for at least one image of a subject that is stored on a device on which the browser is running, a decision support interface that aids the user in determining the state of the subject based on the image, and a template interface that aids the user in capturing uniform descriptive information about the state of the subject. At least two of the viewing interface, the decision support interface, and the template interface operate cooperatively so that actions of the user with respect to one of the two interfaces causes changes in content exposed by the other of the two interfaces.

Abstract: Ingestible devices and methods useful for providing information useful in the diagnosis of gastrointestinal abnormalities are provided.

Abstract: Described herein is an implantable device having a sensor configured to detect an amount of an analyte, a pH, a temperature, strain, or a pressure; and an ultrasonic transducer with a length of about 5 mm or less in the longest dimension, configured to receive current modulated based on the analyte amount, the pH, the temperature, or the pressure detected by the sensor, and emit an ultrasonic backscatter based on the received current. The implantable device can be implanted in a subject, such as an animal or a plant. Also described herein are systems including one or more implantable devices and an interrogator comprising one or more ultrasonic transducers configured to transmit ultrasonic waves to the one or more implantable devices or receive ultrasonic backscatter from the one or more implantable devices. Also described are methods of detecting an amount of an analyte, a pH, a temperature, a strain, or a pressure.

Abstract: An example method includes applying a localization signal to a source electrode positioned within a conductive volume and a ground electrode at a known location. Electrical activity is sensed at a plurality of sensor electrodes distributed across an outer surface of the conductive volume. The locations of each of the sensor electrodes and the location of the ground electrode being stored in memory as part of geometry data. The electrical activity sensed at each of the sensor electrodes is stored in the memory as electrical measurement data. The method also includes computing a location of the source electrode by minimizing a difference between respective pairs of source voltages determined for the plurality of sensor electrodes. The source voltage for each of the sensor electrodes is determined based on the electrical measurement data and the geometry data.