Abstract: The invention provides an antimicrobial personal cleansing composition comprising: (i) an aqueous continuous phase including one or more anionic cleansing surfactants; (ii) a dispersed phase including dispersed particles of zinc pyrithione (ZPT); (iii) a structuring polymer for the aqueous continuous phase which is selected from crosslinked alkali-swellable acrylic emulsion (ASE) polymers; and (iv) from 3 to 20 wt % niacinamide based on the total weight of the composition, wherein the structuring polymer is selected from crosslinked copolymers of (meth)acrylic acid with one or more C1 to C5 alkyl esters of (meth)acrylic acid.

Abstract: A method for reducing muscle contraction of a facial muscle or reducing the appearance of a fine line or wrinkle is disclosed. The method can include topical application of a composition to facial skin and/or to the fine line or wrinkle. The composition can include an effective amount of Rosmarinus officinalis leaf extract, an effective amount of Lavendula stoechas extract, and an effective amount of Acmella oleracea extract. Topical application of the composition to facial skin can reduce muscle contraction of the facial muscle. Topical application of the composition to the fine line or wrinkle can reduce the appearance of the fine line or wrinkle.

Abstract: The present application provides a radiation damage protecting agent comprising hydrogen gas as an active ingredient at a concentration of 18.5% by volume or less, for treating or alleviating, in a hyperbaric capsule under a pressure higher than standard atmospheric pressure, radiation damage in a human patient who has been exposed to radiation or who has received or receives radiotherapy, and a hyperbaric capsule for administering a hydrogen gas-containing therapeutic agent such as the radiation damage protecting agent to a patient including a human.

Abstract: An oil-in-water emulsion cosmetic containing (A) to (E) as essential components and having a pH of 6 or less: (A) an L-ascorbyl tetra fatty acid ester derivative represented by the following general formula (I) Formula 1 wherein R represents a branched alkyl fatty acid residue having 8 to 18 carbons; (B) a polar oil which is liquid at 25° C. and having an IOB value of 0.1 to 0.5; (C) a chelating agent; (D) an antioxidant; and (E) water.

Abstract: A water-in-oil emulsion cosmetic free of stickiness and oiliness, having semi-transparent or transparent appearance to effect feel of freshness, and able to provide moisturized feel is provided. The water-in-oil emulsion cosmetic contains (a) a solid moisturizer, (b) a polyether-modified silicone, and (c) a silicone oil having a refractive index in the range from 1.380 to 1.420 at 25° C., wherein a moisturizer content is 22 mass % or more relative to the total amount of the cosmetic.

Abstract: The present invention relates to cosmetic compositions having antioxidant properties and suitable for any type of skin.

Abstract: The invention pertains to implantable medical devices for controlled delivery of therapeutic agents. Some devices according to the invention have a titanium reservoir, and a porous titanium oxide based membrane to control the rate of release of the therapeutic agent. The reservoir contains a formulation of the active agent, including a stabilizer for the active agent, wherein the stabilizer is provided in an extended release configuration.

Abstract: Compositions for topical application that effectively deliver antioxidants across the epidermis, dermis, or a combination thereof into cells and/or the bloodstream while concurrently maintaining chemical activity of the antioxidants. In certain aspects, these formulations include emulsions and balms each having a lipophilic carrier and a lipophilic antioxidant solubilized by the lipophilic carrier. Also disclosed herein are methods for making these compositions for topical application.

Abstract: This disclosure relates to gastro-resistant, controlled release dosage forms comprising Compound (I): or a pharmaceutically acceptable salt and/or solvate thereof, the pharmacokinetic properties of these dosage forms, and the preparation of the same. The novel dosage forms disclosed herein are useful in reducing the risk of QT prolongation in a subject and in treating a disorder in a subject in need thereof, e.g., a subject diagnosed with schizophrenia, for example, in treating the negative symptoms in a subject diagnosed with schizophrenia having the CYP2D6 EM genotype.

Abstract: [Problem] An adhesion-preventing material having a high adhesion-preventing effect has been demanded. [Solution] An adhesion-preventing material including a sterilized biocompatible sponge-like laminate, wherein the sponge-like laminate comprises a sponge-like first layer and a sponge-like second layer each of which is at least partially crosslinked with a curing agent and comprises a low-endotoxin alginic acid monovalent metal salt, the alginic acid monovalent metal salt in the first layer has a weight average molecular weight of 10,000 to 2,000,000, the alginic acid monovalent metal salt in the second layer has a weight average molecular weight of 1,000 to 1,000,000, the weight average molecular weights are measured by a GPC-MALS method after a decrosslinking treatment, and the weight average molecular weight of the alginic acid monovalent metal salt in the first layer is higher than that in the second layer.

Abstract: The invention is directed to pharmaceutical compositions such as tablets that exhibit delayed release properties when administered as either whole or half tablets. The invention is also directed to delayed release tablets comprising deferiprone for oral administration, for which twice daily administration is bioequivalent to the same daily dose of an immediate release tablet administered thrice daily. The invention is also directed to methods of making and using the same.

Abstract: The present invention provides a cosmetic shaped product: which is substantially formed with relatively low-molecular-weight hyaluronic acid or a water-soluble salt thereof having a high penetrability into the skin; which is easily soluble to water; and which has satisfactory handling properties, and a method for producing the cosmetic shaped product. There is provided a cosmetic shaped product being a sponge-like shaped body formed with at least one polyanionic polysaccharide of hyaluronic acid and a water-soluble salt thereof each having an average molecular weight of 30,000 or lower, the sponge-like shaped body having a bulk specific gravity of 5 to 500 mg/mL. This cosmetic shaped product can be produced by freeze-drying an aqueous solution having a content of the polyanionic polysaccharide of 0.5 to 30% by mass.

Abstract: The present invention relates to a shear-thinning or pseudoplastic cosmetic composition. Zeta potentials may be balanced such that a first ratio of the first zeta potential to the second zeta potential may be approximately 1:2. A second ratio of the first zeta potential to the third zeta potential may be approximately 1:2. And, a third ratio of the second zeta potential to the third zeta potential may be approximately 1:1. Balancing zeta potentials may ensure the shear-thinning cosmetic composition can dispense in its original viscous form and as a fine mist through a single device.

Abstract: The invention provides a 100% anhydrous sunscreen composition and a use of this sunscreen composition with very high water and sweat resistance properties which can be applied on a wet skin, either in the presence of water by repelling water or water droplets respectively or in under-water conditions. The present invention describes a sunscreen composition comprising a silicone organic elastomer blend comprising Dimethicone/Bis-Isobutyl PPG-20 Crosspolymer in Isododecane in a concentration range from about 30% to about 90% w/w and a silicone elastomer comprising Dimethicone/Vinyl Dimethicone Crosspolymer and Silica in a concentration range from about 0.1% to about 10% w/w. The sunscreen may be applied on the skin in the presence of water (in wet and/or under-water conditions). Further, the new sunscreen product allows the consumer to enter water directly after the application of the sunscreen product on his dry or already wet skin.

Abstract: A formed sheet product of a polymer composition comprising at least one protein selected from the group consisting of fibrinogen and thrombin and at least one polymer selected from the group consisting of an aliphatic polyester and a water-soluble polymer, and a laminated formed sheet product comprising a first polymer composition layer composed of fibrinogen and a water-soluble polymer and a second polymer composition layer composed of thrombin and an aliphatic polyester are provided. These formed products are applied onto a wound site and function as a hemostatic material.

Abstract: Combination of dry extract of Rhodiola, dry extract of Tribulus terrestris, dry extract of Undaria pinnatifida, Moringa oleifera, folic acid and vitamin B12 in the form of food supplement for mitigating woman's disorders caused by ageing.

Abstract: A dosage form with a first portion and a second portion. The first portion can be an immediate release portion and can comprise a pain reliever, which can be naproxen or naproxen sodium. The second portion can be an extended release portion and can comprise pseudoephedrine or a pharmaceutically acceptable salt thereof and/or dextromethorphan or a pharmaceutically acceptable salt thereof. The dosage form can optionally comprise a stabilizing agent. The dosage form can be adapted to maintain a therapeutically effective amount of pain reliever, pseudoephedrine, or a pharmaceutically acceptable salt thereof, and/or dextromethorphan, or a pharmaceutically acceptable salt thereof, for at least eight hours.

Abstract: The invention relates to a method for enriching protists with lipids rich in polyunsaturated fatty acids (PUFA) in particular of the omega 3 (?3) class, said method comprising the culture of protists in a culture medium comprising a selenium-containing compound as well as the protists enriched with lipids rich in PUFA obtained by this method. The invention also relates to a method for producing lipids rich in PUFA, comprising, after the enrichment method according to the invention, a method for treating the protists by extraction from the biomass of selenium-containing lipids rich in PUFA. The invention finally relates to any food, cosmetic or pharmaceutical product comprising either selenium-containing lipids thus extracted, or selenium-containing biomass originating from the enrichment method.

Abstract: The present invention relates to settable compositions for use in surgery. The invention also provides related compositions, including surgical kits and packages, as well as methods of making and using the settable compositions.

Abstract: The invention relates to a surface-modified effect pigment comprising particular additives and to the production thereof. The present invention further provides a nail varnish composition comprising a) at least one effect pigment that has been surface-modified with a starting material (additive), where the effect pigment comprises a substrate in platelet form and optionally at least one coating applied to the substrate, b) at least one hydrocarbon resin as binder, and c) at least one solvent or solvent mixture, where the starting material (additive) for surface modification of the effect pigment is at least one compound taken from the group consisting of phosphoric ester-containing, phosphonic ester-containing, phosphonic acid-containing, fatty acid-containing and/or silane-containing compounds or mixtures thereof.