Abstract: Viscous polybutenes of number average molecular weight (M.sub.n) in the range of about 300 to 3000 have improved reactivity with intramolecular anhydrides of unsaturated aliphatic dicarboxylic acids when reacted in the presence of rather small amounts, i.e., 5 to 200 ppm, of alpha halogen-containing, preferably chlorine or bromine-containing, aliphatic or aromatic carbonyls including acetals as additives. Use of such halogen-containing additives in the addition reaction of polybutene with said unsaturated anhydrides can reduce formation of undesired tarry product resulting from polymerization and/or thermal decomposition of the unsaturated anhydrides.
Abstract: Aminobenzoic acids of the structure ##SPC1##Having saluretic and diuretic properties are described. These compounds are prepared by amidation of a 2-halo analog thereof or by alkylation of the free amino compound.
Type:
Grant
Filed:
May 1, 1974
Date of Patent:
April 27, 1976
Assignee:
Merck & Co., Inc.
Inventors:
Edward J. Cragoe, Jr., Otto W. Woltersdorf, Jr.
Abstract: Tranquilizing agents for warm-blooded animals corresponding to the formula ##EQU1## where n can be 1 or 2; Y can be ##EQU2## where R.sup.2 can be hydrogen or an alkyl, alkenyl, alkoxy, phenyl or methoxyphenyl radical. Z can be thienyl, furyl, phenyl; or mono-, di-, or trimethoxyphenyl; mono-, or dichlorophenyl, or dichlorophenoxy. R and R.sup.1 can be hydrogen, methyl, or ethyl and can be the same or different.
Abstract: This invention relates to tetrahydrofuranyl bromoacetates having the formula ##SPC1##And to their utility as selective biocidal agents showing efficacy on bacteria, algae and fungi.
Abstract: In a method for preparing an adduct of (A) a butadiene lower polymer or butadiene lower copolymer and (B) a .alpha.,.beta.-ethylenically unsaturated dicarboxylic acid compound, said method is characterized in that said (A) and (B) are caused to react in the presence of one or more compounds selected from (C) p-phenylenediamine derivatives, catechol derivatives, pyrogallol derivatives, N-nitrosamines, quinoline derivatives and naphthol derivatives, thus serious increase of the viscosity of said adduct in the addition reaction can be prevented.
Abstract: This disclosure describes novel 2,5-dihydro-2,5-dialkoxyfuran derivatives useful as intermediates for the preparation of the natural prostaglandins and their congeners.
Abstract: A method of condensing and recovering phthalic anhydride in dilute concentration in gases discharged from reactors. The method comprises condensing the anhydride on a solid granular carrier moving in a pneumatic conveyor, separating the condensate from its carrier and cooling the said carried in a fluidized bed for recycling it. The method is also application to the condensation of other sublimable substances.
Abstract: The use of certain chloroplatinic complex compounds of the formula:[Pt R.sup.1 Cl.sub.2 ].sub.awherein a is 1 or 2 and R.sup.1 is an unsaturated ketone residue, to catalyze the addition of alkoxy, aryloxy or halo hydrogen silanes to aliphatically unsaturated compounds (carbon to carbon unsaturation such as olefins and/or acetylenes).
Abstract: Compounds of the formula: ##EQU1## wherein R and R' are lower alkyl groups having from 1 to 4 carbon atoms, eventually substituted by a hydroxyl group; n is an integer from 0 to 3 and R' together with the ##EQU2## group jointly represent the group ##EQU3## A process for the preparation of these compounds is also disclosed. The compounds of the invention display interesting pharmacological activities and may be usefully employed as antidepressants.
Type:
Grant
Filed:
December 29, 1972
Date of Patent:
April 6, 1976
Assignee:
Farmitalia Societa Farmaceutica Italia
Inventors:
Giselbert Karl Suchowsky, deceased, Luigi Bernardi, Severina Coda, Lorenzo Pegrassi
Abstract: A method for preparing 2,5-dihalo- and 2,5,6-trihalopyridines corresponding to the formula ##SPC1##Wherein each X independently represents chloro, fluoro or bromo and R represents hydrogen, chloro, fluoro or bromo which comprises reacting a halohydrazinopyridine of one of the formulas ##SPC2##With an excess of an aqueous alkali metal hydroxide in the presence of a reaction medium from the group consisting of loweralkanols of 1 to 4 carbon atoms and loweralkylglycols of 2 to 4 carbon atoms.
Type:
Grant
Filed:
December 27, 1974
Date of Patent:
March 30, 1976
Assignee:
The Dow Chemical Company
Inventors:
Stanley D. McGregor, Herman O. Senkbeil
Abstract: A catalyst useful for the oxidation of organic compounds, particularly vapor-phase oxidation of benzene with molecular oxygen to produce maleic anhydride, comprises the oxides of molybdenum, vanadium, phosphorus, sodium and boron in combination with an oxide of at least one metal of the group consisting of manganese, tin, tungsten and bismuth, and preferably also in combination with an oxide of at least one member of the group consisting of iron, cobalt and nickel.
Abstract: Pyridine bases are produced in higher yield from at least one of aliphatic carbonyl compounds and ammonia by reaction at 350.degree. to 550.degree.C under the atmospheric pressure at a space velocity of 100 to 10,000 hr.sup.-.sup.1 in the presence of a catalyst prepared by immersing silica-alumina or a silica-alumina mixture containing a promoter in an aqueous solution of ammonium halide such as ammonium chloride, ammonium iodide or ammonium bromide at a concentration of not more than 20% by weight at room temperature to 80.degree.C, washing the immersed silica-alumina or the mixture with water, and drying and calcining the same at 300.degree.C or higher. Regeneration of the catalyst after the reaction can be carried out for a much shortened time.
Abstract: Iso-lasalocid (an isomer of lasalocid A) is produced by a species of Streptomyces. The isomer, its halogen derivatives and its salts exhibit antibacterial and antiprotozoal activity and are useful as antibacterial and antiprotozoal agents.
Abstract: Pigmentary-grade .beta.-copper phthalocyanine (or .beta.-CPC) is prepared without the need for a final milling step by high turbulence drowning of an H.sub.2 SO.sub.4 solution of crude CPC in water followed by admixture withA. a water-immiscible halogenated organic liquid andB. fine-particle size .beta.-CPC to serve as crystallizing seed,Followed by recovery of the pigment.
Abstract: A process for separating and purifying biphenyltetracarboxylic dianhdride isomers from a mixture of these isomers by fractional crystallization in aliphatic acid anhydrides or acetone. The isomeric mixture is obtained by heating biphenyltetracarboxylic acids, optionally in the presence of an aliphatic acid anhydride. The biphenyltetracarboxylic acids are obtained by oxidizing coupling dimers of o-xylene or by hydrolyzing coupling dimers of dimethyl phthalate.
Abstract: Compounds corresponding to the formula: ##SPC1##In which R.sub.1 and R.sub.2 are, independently, hydrogen, alkyl, alkoxyalkyl, cycloalkyl, pinonyl, ethylcycloalkyl, lower alkenyl, halogenated lower alkyl, benzyl, ethylphenyl, 2,4-dichlorophenoxy-methylene, styryl, furyl, phenyl or substituted phenyl in which the substituents are nitro, halogen, methyl, or methoxy; R.sub.3 and R.sub.4 are, independently, hydrogen or lower alkyl; X and Y are independently oxygen or sulfur; and Z is halogen, nitro, amino, lower alkyl, lower alkoxy or trifluoromethyl and n is an integer having a value from 0 to 4. The above compounds are effective herbicides, particularly for the control of grasses and broadleaf plants with both pre-emergence and post-emergence activity. Representative compounds are: m-propionamidobutyranilide, m-bis-2,2-dimethylvaleranilide, m-isobutyramido trichloroacetanilide, m-isobutyramido-2-ethylbutyranilide, m-t-butylacetamidopropionanilide, and 3'-N-ethyl propionamido-propionalide.