Abstract: Derivatives of carbonyl-group containing behavior modifying compounds, in which said carbonyl group has been converted to a photolabile group which regenerates the carbonyl group on exposure to radiation, are of value in various methods for the control of animal, and in particular insect, species.

Abstract: An octapeptide inhibitor of myristoylating enzymes is disclosed having an amino acid sequence as follows or a physiologically acceptable amide or salt derivative thereof: ##STR1##

Abstract: An octapeptide inhibitor of myristoylating enzymes is disclosed having an amino acid sequence as follows or a physiologically acceptable amide or salt derivative thereof: ##STR1##

Abstract: This invention relates to method for suppressing a transplantation immunity and treating an allergic disease and an autoimmune disease in a mammal which comprises administering spergualin or a pharmaceutically acceptable salt thereof in effective amount to the said mammal.

Abstract: Method for the preparation of esters of a non-reducing sugar like sucrose and one or more fatty acids by transesterification of a non-reducing sugar with one or more fatty acid esters in at first a worm shaft reactor operating at elevated temperature and pressure and then in a second reactor operating at reduced pressure and elevated temperature. Such esters of a non-reducing sugar and fatty acids, in particular the monoesters and diesters are valuable solid surfactants, which are non-toxic, odorless, tasteless, non-irritating to the skin and hydrolyze in the human and animal tract to normal good products.

Abstract: Crosslinked hemoglobin preparations of extended shelf life and high oxygen transport capacity can be made by reducing a hemoglobin solution with an oxygen consuming reducing agent down to an oxygen partial pressure of 0 mbar, then adding an effector, crosslinking with a dialdehyde, reducing with a carbonyl-group-specific reducing agent, circulating through an ultrafilter, and stabilizing the product by adding a reducing agent thereto.

Abstract: A method for purifying recombinant tumor necrosis factor from cultures of microorganisms transformed with vectors that code for the production of tumor necrosis factor is disclosed. A sequence of contacting steps is involved, such that the effluent from the first contacting step can be contacted directly with the contacting material used for the second step and similarly, the effluent from the second contacting step can be contacted directly with the contacting material used for the third contacting step. In a preferred embodiment, tumor necrosis factor-containing fermentation broth can be substantially purified by a single pass through a multi-component chromatography system, i.e., the first, second and third contacting materials are each packed in a column configuration, with TNF-containing broth being passed directly through the sequence of columns.

Abstract: Novel peptide antibiotics designated herein as BU-2867T F and G are produced by fermentation of Polyangium brachysporum strain K481-B101 (ATCCC 53080). The new antibiotics are found to have antifungal activity and to inhibit P388 lymphatic leukemia in rodents.

Abstract: A dentifrice sachet wherein the sachet which envelops the dentifrice is a plastic laminate material having a modified acrylonitrile methyl acrylate copolymer inner surface. The sachet is subject to reduced delamination when in contact with a paste or gel dentifrice.

Abstract: This invention provides injectable semi-solid formulations comprising a pharmaceutically or veterinary active agent, an oil and a suitable glyceride release modifying agent.

Abstract: A dental treating composition and method are disclosed which reduces dental plaque and inhibits future formation of the same, when the dental treating composition is used on regular basis. Sodium alginate is used as a calcium ion chelating agent which weakens the bond between the plaque and the teeth thereby allowing easy removal by subsequent brushing. The use of benzalkonium chloride and zinc sulfate with the composition provides for desensitizing the teeth and elimination of halitosis.

Abstract: Intestine-specific delivery of an opioid antagonist can be accomplished without substantial central nervous system effects by administering the antagonist orally in the form of the glucuronide derivative.

Abstract: An active antioxydant containing a compound shown by structural formula ##STR1## is produced by applying an acid catalyst to sesamolin substantially in the absence of active hydrogen compounds.

Abstract: In an oral composition comprising an amino compound, for example, tranexamic acid and .epsilon.-aminocaproic acid, a flavor, a surface-active agent, water, and optionally, a humectant, a binder, and an abrasive, the flavor is at least partially comprised of an aldehyde flavor compatible with the amino compound.

Abstract: A cosmetically and therapeutically stable antiplaque dentifrice comprising a combination of hexetidine, a soluble zinc salt and a fluoride compound capable of providing a fluoride ion, as the antiplaque agent in dental vehicle containing a polyethylene glycol humectant and a dental abrasive.

Abstract: A composition which combines autogenic bone marrow with a suspension of purified atelopeptide reconstituted collagen is used to repair bone defects in mammals.

Abstract: New 8-substituted nucleoside and purine derivatives of the general formula: ##STR1## wherein R represents an amino group or an hydroxy group possibly in the corresponding keto tautomeric form, R.sub.1 is hydrogen or an amino group, R.sub.2 is hydrogen or a .beta.-D-ribofuranosyl radical wherein the primary hydroxy group and/or the two secondary hydroxy groups may be derivatized, R.sub.3 is an optionally substituted aryl or monocyclic heteroaryl radical and, X is --O-- or --S--. The new compounds have antihyperlipaemic activity.

Abstract: The invention relates to a method of promoting the fat digestion and absorption, which comprises orally administering to an animal subject a partially methylated-.beta.-cyclodextrin optionally together with pharmaceutically acceptable auxiliary and/or additive materials.

Abstract: An oily composition of aclarubicin or aclarubicin hydrochloride comprising aclarubicin or aclarubicin hydrochloride; at least one fatty acid selected from saturated medium chain fatty acids, unsaturated medium chain fatty acids and unsaturated long chain fatty acids; and at least one fats and oils selected from iodized oils and vegetable oils.

Abstract: Polypeptides are disclosed which inhibit the binding of the C5a chemotaxin to polymorphonuclear leukocytes by cleaving a six amino acid peptide from the carboxy-terminus of the C5a chemotaxin. The polypeptides can be isolated from virulent strains of group A streptococci, s. pyogenes, by enzymatic or detergent extraction.