Abstract: Embodiments herein include testing articles to assess hydration of a test subject. The testing articles can include a carrier portion having a porous medium through which a fluid of the test subject moves. The carrier portion can include a first end and a second end opposite the first end. The testing articles can include a first chemical composition disposed in the porous medium that reacts with chloride ions to produce a first color change. The testing articles can include a wick that is in direct contact with the first end of the carrier portion to allow the transfer of the fluid from the wick to the carrier portion. The testing articles can include a fill indicator element in direct contact with the second end of the carrier portion to allow the transfer of the fluid from the carrier portion to the fill indicator element. Other embodiments are also included herein.

Abstract: Systems for monitoring left atrial pressure using implantable cardiac monitoring devices and, more specifically, to a left atrial pressure sensor implanted through a septal wall are presented herein.

Abstract: A handheld, conforming capacitive sensing apparatus configured to measure Sub-Epidermal Moisture (SEM) as a mean to detect and monitor the formation of pressure ulcers. The device incorporates an array of electrodes which are excited to measure and scan SEM in a programmable and multiplexed manner by a battery-less RF-powered chip. The scanning operation is initiated by an interrogator which excites a coil embedded in the apparatus and provides the needed energy burst to support the scanning/reading operation. Each electrode measures the equivalent sub-epidermal capacitance corresponding and representing the moisture content.

Abstract: In a biopotential-physiological-phenomena sensing system, an impedance measurement circuit for measuring the impedance of a channel electrode that is applied to a subject's body for sensing a physiological phenomenon includes: an amplifier, a DC-biased power supply with an AC component and a conductive element. The amplifier has a signal input coupled to a channel electrode that is applied to a subject's body and a signal output for providing an output voltage that is representative of a voltage provided at the signal input in accordance with an amplification of the amplifier. The conductive element is coupled between the power supply and the signal input of the amplifier. The AC component of the DC-biased power supply causes a known test current to flow through the channel electrode thereby causing a voltage drop proportional to the impedance of the channel electrode at the input of the amplifier. The impedance of the channel electrode is measured in accordance with the amplifier's output voltage.

Abstract: A two part patient monitoring device includes an activator module and a sensor device. The activator module includes a non-galvanic data port that creates a communication path with a non-galvanic data port on the sensor device. The activator module includes power contact pads that are each at least partially surrounded by a bias ring. A bias voltage is applied to the bias rings and a processor or circuit in the activator module monitors the voltage on the bias ring to detect a leakage current. The sensor module includes power contact pins that engage the power contact pads to transfer power from the activator module to the sensor device. Each of the contact pins are surrounded by a seal member such that the connection between the power contact pins and the power contact pads is protected from debris and/or moisture.

Abstract: A method and system are disclosed for use in monitoring/screening/diagnosing sleep or wake state of a subject or patient. The method generally includes monitoring the patient's activity during one or more sleep sessions comprising a plurality of intervals known as epochs. The sleep/wake state of the subject is determined during each epoch of the session using actigraphy data obtained during the monitoring session. The actigraphy data provides information about the activity of a patient during an epoch. The sleep or wake state is determined based on a ratio of the activity count during an epoch to the activity count during a preceding epoch. If the ratio is greater than a first activity threshold, then a “wake” indication may be provided by, for example, the system. Alternatively, or additionally, a “wake” indication may be determined if the activity count during the epoch is greater than a threshold.

Abstract: This invention is a system for nutritional monitoring and management which includes a camera, a spectroscopic sensor, a fiducial component, a wearable biometric sensor, a smart utensil or dish, a passive feedback mechanism which provides a person with information concerning food item types and/or quantities, and an active stimulus mechanism which modifies the person's food-related physiological processes. This system can help a person to improve their dietary habits and health.

Abstract: This disclosure relates to a glucose-sensing electrode including a nanoporous layer on an electrically conductive surface. The nanoporous layer includes a three-dimensional interconnected network of irregularly shaped bodies that are formed of numerous nanoparticles having a generally oval or spherical shape with a length ranging between about 2 nm and about 5 nm. Inside the three-dimensional interconnected network of irregularly shaped bodies, at least part of the nanoparticles are adjacent to each other without an intervening nanoparticle therebetween and apart from each other to define interparticular nanopores therebetween, wherein at least part of the interparticular nanopores inside the three-dimensional interconnected network of irregularly shaped bodies are in a size ranging between about 0.5 nm and about 3 nm.

Abstract: Method and system including displaying a first representation of a medication treatment parameter profile, displaying a first representation of a physiological profile associated with the medication treatment parameter profile, detecting a modification to a segment of the medication treatment parameter profile, displaying a modified representation of the medication treatment parameter profile and the physiological profile based on the detected modification to the segment of the medication treatment parameter profile, modifying an attribute of the first representation of the medication treatment parameter profile, and modifying an attribute of the first representation of the physiological profile are provided.

Abstract: This disclosure relates to an apparatus for glucose-sensing that address interference of ascorbic acid and acetaminophen. The apparatus includes a first electrode capable of oxidizing glucose and at least one of ascorbic acid and acetaminophen. The apparatus further includes a second electrode capable of oxidizing at least one of ascorbic acid and acetaminophen but not capable of oxidizing glucose. The first electrode includes a deposit of irregularly shaped bodies that are formed of numerous nanoparticles having a generally oval or spherical shape with a length ranging between about 2 nm and about 5 nm. The deposit is substantially free of a surfactant. If any surfactant is contained in the deposit, the surfactant is in an amount smaller than 0.5 parts by weight with reference to 100 parts by weight of the deposit. The first electrode does not include a glucose-specific enzyme.

Abstract: A diversified glucose sensor system comprises an introducer needle and two or more independent sensor bodies, each sensor body having one or more sensing elements that can be subcutaneously positioned in a patient's body by insertion of the introducer needle for glucose measurement. The system further includes a progressive insertion device comprising an insertion shaft that pushes the sensor bodies out the end opening of the introducer needle to a desired depth in the patient prior to removal of the insertion shaft and the introducer needle. The sensor bodies are bent or folded and held under stress within the introducer needle for insertion, and released and biased outwardly when pushed out of the introducer needle. The sensing elements are anchored and disposed within the patient at positions providing X/Y/Z-axis diversity for measurement.

Abstract: Systems and methods for assessing PPG signals generated based on transdermal optical data can include a computing device generating a color intensity signal using an acquired sequence of transdermal images of a subject. The computing device can compute a signal quality metric of the color intensity signal. The computing device can provide an indication of a quality of the color intensity signal for display on a display device associated with the computing device. The indication of the quality of the color intensity signal can be determined based on the signal quality metric.

Abstract: A sphygmomanometer includes: a first fluid bag that is to be worn around a measurement site; first and second pulse wave sensors that are mounted on first fluid bag, and detect pulse waves of respective opposing areas of an artery running along measurement site; pressing parts that locally presses areas corresponding to first and second pulse wave sensors from an outer circumference side, opposite of an inner circumference side of first fluid bag where first and second pulse wave sensors are mounted. Blood pressure is calculated based on pulse transit time obtained from outputs from first and second pulse wave sensors, with first fluid bag in an unpressurized state and first and second pulse wave sensors being pressed by a pressing force of the pressing part. Blood pressure is calculated, for oscillometric blood pressure measurement, based on pressure within first fluid bag with first fluid bag in a pressurized state.

Abstract: A gas control device includes a pump, a valve, a cuff, and a controller. The valve includes a first plate having a first vent hole and a first vent hole, a channel forming plate having an exhaust hole and an exhaust channel, a second plate having a second vent hole, and an edge separation plate. A manchette rubber tube in the cuff is joined to the periphery of the second vent hole in the second plate by an adhesive, and thus the valve is connected to the cuff. The exhaust hole is opened to the atmosphere. The pump includes a pump housing having a discharge hole and a discharge hole. The upper surface of the pump housing is joined to the bottom surface of the edge separation plate.

Abstract: A portable handheld sampling device for collecting aerosol particles in a stream of exhaled breath provided with an inlet and an outlet, wherein the sampling device further comprises a housing and a collecting device holder removably arranged at least partially inside the housing, wherein the housing and the collecting device holder are arranged to guide the stream of exhaled breath through the device from the inlet to the outlet, wherein said collecting device holder comprises at least two cylindrical conduits arranged in parallel, each defining a flow path in fluid connection with the inlet, wherein a cylindrical collecting device is arranged in each conduit, the collecting device being adapted to collect the aerosol particles in the exhaled breath. A method for collecting aerosol particles in exhaled breath of a user using a portable handheld sampling device by means of a reopening breathing maneuver.

Abstract: Provided are an apparatus and method for measuring bio-information. The apparatus for measuring bio-information includes: a pulse wave sensor configured to emit light of multiple wavelengths onto an object, and detect the light to obtain multi-wavelength pulse wave signals when the light is reflected or scattered from the object; and a processor configured to: obtain a conversion signal that indicates a contact pressure between the object and the pulse wave sensor, based on the multi-wavelength pulse wave signals, obtain an oscillometric envelope based on the multi-wavelength pulse wave signals and the conversion signal, and obtain bio-information based on the oscillometric envelope.

Abstract: A diagnosis assistance apparatus, a diagnosis assistance method, a diagnosis assistance program, and a bodily information measurement apparatus, assist diagnosis by outputting information that is useful for the diagnosis. A bodily information measurement apparatus includes a data acquisition unit that acquires data for analysis in which bodily information measured from a measurement subject and position information of the measurement subject at the time of measuring the bodily information are associated; an index generation unit that, based on bodily information associated with position information that is included in the data and belongs to multiple pieces of pre-registered location information, generates numerical value indices for determining a bodily state of the measurement subject with respect to the respective pieces of location information; and an output unit that performs output based on the numerical value indices generated for the multiple pieces of location information.

Abstract: Gastric resident electronics, devices, systems, and related methods are generally provided. Some embodiments comprise administering (e.g., orally) an (electronic) resident structure to a subject (e.g., a patient) such that the (electronic) resident structure is retained at a location internal to the subject for a particular amount of time (e.g., at least about 24 hours) before exiting said location internal to the subject. In some embodiments, the resident structure is a gastric resident electronic. That is to say, in some embodiments, the resident structure is configured for relatively long gastric residence and comprises an electronic component. In some embodiments, the structures and components described herein may comprise one or more components configured for the delivery of an active substance(s) (e.g., a pharmaceutical agent) to the subject.

Abstract: A method and system for contextual heart rate monitoring are disclosed. In a first aspect, the method comprises calculating a heart rate using a detected ECG signal and detecting an activity level. In a second aspect, the system comprises a wireless sensor device coupled to a user via at least one electrode, wherein the wireless sensor device includes a processor and a memory device coupled to the processor, wherein the memory device stores an application which, when executed by the processor, causes the processor to calculate a heart rate using a detected ECG signal and to detect an activity level.

Abstract: A smart cage includes radiofrequency transceivers and tags attached to laboratory animals. The tags include sensors to detect monitorable conditions of the laboratory animals. The sensors include working electrodes, counter electrodes, reference electrodes, and potentiostats. The top surface of the electrodes is coated with ionophores or enzymes which detect the monitorable conditions of the laboratory animals.