Patents Examined by Jeffrey T Palenik
  • Cosmetic compositions containing diglycerol tetrapelargonate
    Patent number: 11123274
    Abstract: The invention concerns cosmetic compositions comprising diglycerol tetrapelargonate, or a mixture of diglycerol tetrapelargonate with one or more esters selected from neopentylglycol dipelargonate, glycerol tripelargonate, pentaerythritol tetrapelargonate, and their use for the care of the skin and hair, and in make-up and in hygiene products.
    Type: Grant
    Filed: May 4, 2017
    Date of Patent: September 21, 2021
    Assignee: NOVAMONT S.P.A.
    Inventors: Luigi Capuzzi, Francesca DiGioia, Vanessa Bramati, Federica Carlomagno, Alessandra Cominetti
  • High-performance hair treatment agents with increased care effect
    Patent number: 11123275
    Abstract: The split end-reducing effect of anteiso fatty acid quats can be further enhanced by alkyldimethylammonium hydroxypropyl hydrolyzed keratin so that hair treatment agents containing at least one anteiso fatty acid quat and alkyldimethylammonium hydroxypropyl hydrolyzed keratin are particularly effective in reducing split ends.
    Type: Grant
    Filed: August 28, 2018
    Date of Patent: September 21, 2021
    Assignee: HENKEL IP & HOLDING GMBH
    Inventors: Monika Nebel, Erik Schulze zur Wiesche
  • Process for encapsulating soluble biologics, therapeutics, and imaging agents
    Patent number: 11103461
    Abstract: An “inverse” precipitation route to precipitate aqueous soluble species with copolymers as nanoparticles having a hydrophilic, polar core and a less polar shell is described. The aggregation of these nanoparticles to form larger microparticles and monoliths provides a highly loaded construct (e.g., a depot) for the sustained and controlled release of actives.
    Type: Grant
    Filed: December 21, 2016
    Date of Patent: August 31, 2021
    Assignee: THE TRUSTEES OF PRINCETON UNIVERSITY
    Inventors: Robert K. Prud'Homme, Robert F. Pagels, Chester E. Markwalter
  • Cross-linking agents and associated methods
    Patent number: 11065275
    Abstract: An ophthalmic composition or dosage form can include a therapeutically effective amount of a cross-linking agent and a pharmaceutically acceptable carrier. The composition or dosage form can be used to treat an ophthalmic condition by administering a therapeutically effective amount of the composition to an eye of a subject during a treatment period.
    Type: Grant
    Filed: December 6, 2016
    Date of Patent: July 20, 2021
    Assignee: University of Utah Research Foundation
    Inventors: Balamurali K. Ambati, Hironori Uehara, Santosh Muddana
  • Water dispersible formulations
    Patent number: 11013245
    Abstract: The present invention relates to water dispersible formulations of 3-nitrooxypropanol and derivatives thereof as well as to the production of such formulations.
    Type: Grant
    Filed: February 9, 2018
    Date of Patent: May 25, 2021
    Assignee: DSM IP ASSETS B.V.
    Inventors: Dominik Josef Brunner, Laure Clasadonte, Christine Gothscheck, Olivia Brigitte Vidoni, Silvia Maria Wollgast
  • Amplified photodegradation of hydrogels and methods of producing the same
    Patent number: 11000625
    Abstract: This invention is in the field of synthesis and amplified photodegradation of hydrogel network and methods of producing and using the same.
    Type: Grant
    Filed: June 1, 2018
    Date of Patent: May 11, 2021
    Assignee: The Regents of the University of Colorado, a body corporate
    Inventors: Kristi Anseth, Ian Marozas, Tobin Brown
  • Manufacturing of small film strips
    Patent number: 10940626
    Abstract: The present invention relates to methods for forming films. In particular, the present invention relates to the formation of films on a substrate via the use of individual pumps to deposit individual wet film products onto a substrate.
    Type: Grant
    Filed: March 1, 2019
    Date of Patent: March 9, 2021
    Assignee: Aquestive Therapeutics, Inc.
    Inventor: Beuford A. Bogue
  • Multi-layer biomaterial for tissue regeneration and wound healing
    Patent number: 10912862
    Abstract: The technology described herein is directed to compositions comprising at least a first porous biomaterial layer and a second impermeable biomaterial layer and methods relating thereto. In some embodiments, the compositions and methods described herein relate to wound healing, e.g. repair of wounds and/or tissue defects.
    Type: Grant
    Filed: February 5, 2013
    Date of Patent: February 9, 2021
    Assignees: Children's Medical Center Corporation, Tufts University
    Inventors: Joshua R. Mauney, Carlos R. Estrada, David L. Kaplan, Eun Seok Gil
  • Methods for storing cysteamine formulations and related methods of treatment
    Patent number: 10905662
    Abstract: Methods of storing and methods of stabilizing pharmaceutical compositions comprising cysteamine, or a pharmaceutically acceptable salt thereof, are provided. Methods of distributing pharmaceutical compositions comprising cysteamine, or a pharmaceutically acceptable salt thereof, and methods of treating cystinosis also are provided.
    Type: Grant
    Filed: November 15, 2019
    Date of Patent: February 2, 2021
    Assignee: Horizon Orphan LLC
    Inventors: Michael Desjardin, Mark Johnson
  • Compositions and methods of use of cis-4-[2-{[(3S,4R)-3-fluorooxan-4-yl]amino}-8-(2,4,6-trichloroanilino)-9H-purin-9-yl]-1-methylcyclohexane-1-carboxamide
    Patent number: 10898488
    Abstract: Provided are formulations and dosage forms of cis-4-[2-{[(3S,4R)-3-fluorooxan-4-yl]amino}-8-(2,4,6-trichloroanilino)-9H-purin-9-yl]-1-methylcyclohexane-1-carboxamide, alternatively named (1s,4s)-4-(2-(((3S,4R)-3-fluorotetrahydro-2H-pyran-4-yl)amino)-8-((2,4,6-trichlorophenyl)amino)-9H-purin-9-yl)-1-methylcyclohexane-1-carboxamide, or a pharmaceutically acceptable salt, tautomer, solvate, hydrate, co-crystal, clathrate, or polymorph thereof.
    Type: Grant
    Filed: April 10, 2020
    Date of Patent: January 26, 2021
    Assignee: Celgene Corporation
    Inventors: Scott Bone, Tracy Lee Gaebele, Yu Pu, Lianfeng Huang
  • Polyphosphazene polyelectrolytes and uses thereof
    Patent number: 10858483
    Abstract: Polyphosphazenes polyelectrolytes. The polyphosphazenes can be prepared by substituting pendant groups (e.g., ionic groups or pendant groups that can form ionic groups) onto a reactive macromolecular precursor for example, by reaction between the reactive chlorine atoms on the backbone of poly(dichlorophosphazene) and appropriate organic nucleophiles. In certain examples, one or more charged pendant groups of a polyphosphazene is/are further modified to introduce desired counterions, which can be hydrophobic counterions. The polyphosphazenes can activate distinct Toll-Like Receptors (TLRs) and can be used in methods of stimulating an immune response.
    Type: Grant
    Filed: July 6, 2017
    Date of Patent: December 8, 2020
    Assignee: University of Maryland, College Park
    Inventors: Alexander K. Andrianov, Thomas R. Fuerst, Peter Fusco, Alexander Marin
  • Organopolysiloxane, acid-neutralized salt thereof, and applications thereof
    Patent number: 10806691
    Abstract: A silicone material is provided. The silicone material is an organopolysiloxane or acid-neutralized salt thereof that contains a side-chain bonded hydrophilic group having a tertiary-amine structure and represented by the general formula: —CqH2q—O—CH2—CH(OH)—CH2—N(RQ1)(RQ2) wherein q is a number ranging from 1 to 6, and wherein each of RQ1 and RQ2 is independently a halogen-substituted or non-substituted monovalent hydrocarbon group or an alkanol group. At least one of RQ1 and RQ2 has a hydroxyl group, provided the total number of hydroxyl groups in RQ1 and RQ2 is at most three (3). Any of RQ1 and RQ2 does not have a nitrogen atom in the group. The silicone material has a number of beneficial properties.
    Type: Grant
    Filed: April 26, 2017
    Date of Patent: October 20, 2020
    Assignees: DOW SILICONES CORPORATION, DOW TORAY CO., LTD.
    Inventors: Eric Jude Joffre, Lenin James Petroff, Seiki Tamura
  • Storage-stable formulations
    Patent number: 10806706
    Abstract: The present invention relates to storage-stable formulations of 3-nitrooxypropanol and derivatives thereof as well as to the production of such formulations.
    Type: Grant
    Filed: February 9, 2018
    Date of Patent: October 20, 2020
    Assignee: DSM IP ASSETS B.V.
    Inventors: Dominik Josef Brunner, Laure Clasadonte, Christine Gothscheck, Olivia Brigitte Vidoni
  • Pharmaceutical compositions
    Patent number: 10772877
    Abstract: The present invention relates to the field of methods for providing pharmaceutical compositions comprising poorly water-soluble drugs. In particular the present invention relates to compositions comprising stable, amorphous hybrid nanoparticles, comprising at least one protein kinase inhibitor and at least one polymeric stabilizing and matrix-forming component, useful in pharmaceutical compositions and in therapy.
    Type: Grant
    Filed: February 7, 2020
    Date of Patent: September 15, 2020
    Assignee: XSPRAY MICROPARTICLES AB
    Inventors: Magnus Brisander, Mustafa Demirbüker, Gérald Jesson, Martin Malmsten, Helene Dérand
  • Skin-adhesive silicone gel
    Patent number: 10758640
    Abstract: Silicone gels are described that are adhesive to the skin. The gels can be used in particular for articles that are adhesive to the skin for medical or paramedical use.
    Type: Grant
    Filed: March 16, 2017
    Date of Patent: September 1, 2020
    Assignee: ELKEM SILICONES FRANCE SAS
    Inventors: Caroline Moine, Maryline Quemin, Gaelle Cros
  • Radiation sterilization of hypercompresed polymer dosage forms
    Patent number: 10744099
    Abstract: A sterile pharmaceutical dosage form which comprises an ester capped lactide polymer, glycolide polymer or a lactide-glycolide copolymer hypercompressed with an active pharmaceutical ingredient wherein said sterile pharmaceutical dosage form has been sterilized with an electron beam and a method of preparing said sterile pharmaceutical dosage form.
    Type: Grant
    Filed: November 19, 2019
    Date of Patent: August 18, 2020
    Assignee: SUSTAINED NANO SYSTEMS LLC
    Inventors: Barry M. Libin, Jeffrey M. Liebmann, Weiliam Chen
  • Sustained release suspension containing dezocine analogue ester and preparation method therefor
    Patent number: 10744109
    Abstract: Disclosed are a sustained release suspension containing dezocine analogue ester and a preparation method therefor. According to the present invention, an injectable oily auxiliary material which may pharmaceutically serve as a sustained-release depot and an excipient are selected, and micronization technology is used jointly with high pressure homogenization technology and an anti-solvent technique to prepare an injectable long-acting suspension. The main components of the suspension are a compound represented by formula (I), the injectable oil, and the like.
    Type: Grant
    Filed: August 7, 2018
    Date of Patent: August 18, 2020
    Assignee: SHANDONG DANHONG PHARMACEUTICAL CO., LTD.
    Inventors: Yang Zhang, Bing Deng, Jiahu Wu, Wentao Wu, Zhixiang Li
  • Mic reduction with lithium ions
    Patent number: 10743541
    Abstract: The invention relates to a process for reducing the minimum inhibitory concentration (MIC) of a biocide against at least one strain of bacteria and/or at least one strain of yeast and/or at least one strain of mould in an aqueous preparation. The invention further relates to the use of a water soluble source of lithium ions for reducing the minimum inhibitory concentration (MIC) of a biocide against at least one strain of bacteria and/or at least one strain of yeast and/or at least one strain of mould in an aqueous preparation.
    Type: Grant
    Filed: April 8, 2015
    Date of Patent: August 18, 2020
    Assignee: Omya International AG
    Inventors: Anita Zumsteg, Joachim Glaubitz, Simon Urwyler, Matthias Buri, Patrick A. C. Gane
  • 3D printable hydrogel materials
    Patent number: 10738297
    Abstract: Hydrogel compositions including a polymer uniformly embedded with a loading agent are provided. Also provided are methods for extrusion printing hydrogel compositions to provide extruded hydrogel compositions, which can be crosslinked to provide crosslinked hydrogel structures. Also provided are methods for using crosslinked hydrogel structures in chemical processes.
    Type: Grant
    Filed: May 12, 2017
    Date of Patent: August 11, 2020
    Assignee: University of Washington
    Inventors: Rose Ann Cattolico, Chloe Ramos Deodato, Alshakim Nelson, Robert Jun Ono, Abhijit Saha, Trevor Gerald Johnston, Dylan Gary Karis
  • Dietary supplement formulations for hair
    Patent number: 10736882
    Abstract: Dietary supplement compositions directed to men and women and to the maintenance and improvement of human physiology, including weight, skin, hair, and general organ function and sexual health.
    Type: Grant
    Filed: August 26, 2019
    Date of Patent: August 11, 2020
    Inventor: Amen Dhyllon