Patents Examined by John McGuirk
  • Patent number: 11714096
    Abstract: An automated carousel and system configured for translationally moving a plurality of biological production units in unison along a vertical frame while maintaining a precise alignment of each of the biological production units relative to gravity, and simultaneously providing independent dynamic adjustment of the axial orientation of each of the plurality of biological production units relative to gravity. The automated carousel may be adapted for use with a variety of biological production units supporting cell culture and/or tissue engineering systems in various clinical and laboratory settings and provides for ergonomic use thereof.
    Type: Grant
    Filed: December 18, 2019
    Date of Patent: August 1, 2023
    Assignee: OCTANE BIOTECH INC.
    Inventors: Timothy Smith, Ian Grant, Guy Oram, Chase McRobie, Raelyn Daniels, Taylor Plant
  • Patent number: 11709171
    Abstract: A laboratory system for a laboratory automation system is presented. The laboratory system comprises a sample container carrier. The sample container carrier is configured to carry a laboratory sample container and comprises a removal detector. The removal detector is configured to interact with the laboratory sample container to detect a removal of the carried laboratory sample container from the sample container carrier. Furthermore, the laboratory system is configured to determine based on the detected removal that a before valid logic assignment of the sample container carrier to the carried laboratory sample container is invalid.
    Type: Grant
    Filed: March 4, 2019
    Date of Patent: July 25, 2023
    Assignee: ROCHE DIAGNOSTICS OPERATIONS, INC.
    Inventors: Martin Kopp, Oliver Gutmann, Norbert Schmitt
  • Patent number: 11709173
    Abstract: Disclosed are high-throughput vessel supply systems and methods of supplying sample vessels, such as samples stored in test tubes. A system for supplying a plurality of individual vessels that each contains a sample is disclosed.
    Type: Grant
    Filed: October 26, 2021
    Date of Patent: July 25, 2023
    Assignee: Laboratory Corporation of America Holdings
    Inventors: David Wilson, Jay Krajewski, Kevin Meyer
  • Patent number: 11709174
    Abstract: Disclosed are high-throughput vessel sorting systems and methods of sorting sample vessels, such as samples stored in test tubes. A system for sorting a plurality of individual vessels that each contains a sample is disclosed.
    Type: Grant
    Filed: April 29, 2022
    Date of Patent: July 25, 2023
    Assignee: Laboratory Corporation of America Holdings
    Inventors: David Wilson, Jay Krajewski, Kevin Meyer
  • Patent number: 11703518
    Abstract: A sample analysis system is available that can include a remote sampling system, at least one analyzer, and a controller. The remote sampling system can include a plurality of sample sources for providing a corresponding sample therefrom; and a plurality of sample collection devices selectively coupled to any of the plurality of sample sources for receiving at least one of the samples therefrom. The at least one analyzer can be coupled to the plurality of the sample collection devices for receiving at least one of the samples therefrom. The controller can be coupled with the remote sampling system and the at least one analyzer, the controller configured to control which of the sample sources is actively coupled to a given sample collection device at a given time.
    Type: Grant
    Filed: September 29, 2020
    Date of Patent: July 18, 2023
    Assignee: Elemental Scientific, Inc.
    Inventors: Tyler Yost, Jonathan Hein, Jae Seok Lee, Dong Cherl Park
  • Patent number: 11686741
    Abstract: The object of the invention is to realize an automatic analyzer capable of suppressing an increase in cost without greatly changing the configuration even when the configuration of an inspection system is changed, and reducing burden of an operator. A pin to be fitted into a hole formed in a specimen container conveying unit is formed on a specimen container conveying unit mounting surface at a position below a specimen suction position, and it is possible to make relative positions between components of a specimen dispensing unit and the specimen container conveying unit at the time of a specimen dispensing operation, as well as driving conditions when moving each axis of the specimen dispensing unit identical even when the types of the specimen container conveying unit are different, and it is possible to ensure stability of the same specimen dispensing operation before and after changing the specimen container conveying unit.
    Type: Grant
    Filed: July 6, 2018
    Date of Patent: June 27, 2023
    Assignee: Hitachi High-Tech Corporation
    Inventors: Takenori Okusa, Susumu Sakairi
  • Patent number: 11680950
    Abstract: A scanning apparatus that can include (a) a scan actuator including a linear actuator and a mount for a removeable vessel, wherein the mount has a mechanical fastener that is configured to engage a complementary mechanical fastener on the removeable vessel, and wherein the linear actuator is configured to translate the mount while the mechanical fastener engages the complementary mechanical fastener on the removeable vessel; (b) a reference surface; and (c) a preload configured to urge the vessel to contact the reference surface, wherein the linear actuator is configured to slide the vessel along the reference surface while the preload urges the vessel to contact the reference surface.
    Type: Grant
    Filed: February 20, 2020
    Date of Patent: June 20, 2023
    Assignee: Pacific Biosciences of California, Inc.
    Inventors: Matias Negatu, Alex Nemiroski, Drew Ival Frerichs, Dale Buermann, Michael John Erickstad, Rebecca McGinley, Harry Scott Rapoport, Arnold Oliphant, Eugene Pogrebinsky
  • Patent number: 11662356
    Abstract: A sample installation part in which a sample container accommodating a sample to be subjected to biochemical analysis is installed, and consumables installation parts in which consumables to be used for the biochemical analysis are installed are accommodated in an apparatus body of a biochemical analysis apparatus. The apparatus body is provided with an opening part that leads to a sample tray. An instruction receiving unit receives a movement instruction for moving the sample tray from a normal position where the sample installation part is disposed on the opening part side to a consumables replenishment position where the consumables installation parts are disposed on the opening part side. A driving control unit moves the sample tray from the normal position to the consumables replenishment position in a case where the movement instruction is received by the instruction receiving unit.
    Type: Grant
    Filed: August 14, 2019
    Date of Patent: May 30, 2023
    Assignee: FUJIFILM Corporation
    Inventors: Jumpei Shiraishi, Shigetoshi Ishikawa
  • Patent number: 11656238
    Abstract: The automatic analyzer includes a storage unit storing the reaction containers of cleaning target by day unit in such a manner that all the reaction containers mounted on a reaction disk are to be cleaning target within a plurality of days, and a control unit exerts a control in such a manner that during an operation state after the sample of analysis object is dispensed to the reaction containers, a sample of analysis object in each of the reaction containers is analyzed, and not the sample but a detergent is dispensed to the reaction containers of cleaning target of an appointed day, the reaction containers of cleaning target of the appointed day being stored in the storage unit, to soak and wash the reaction containers for a certain time.
    Type: Grant
    Filed: January 12, 2018
    Date of Patent: May 23, 2023
    Assignee: HITACHI HIGH-TECH CORPORATION
    Inventors: Takashi Nakasawa, Tetsuji Kawahara, Masaharu Nishida, Yoko Inoue, Kenichi Yagi, Osamu Matsumoto, Sayaka Asada
  • Patent number: 11647993
    Abstract: An oral fluid collection device is provided that includes a borosilicate glass collection tube that can be capped post-collection for containing a human donor's expectorated oral fluid. The collection tube has a lyophilized reagent disposed therein that is essentially free of surfactants and solvents and includes a bacteriostatic, a peptidoglycan cleaving enzyme, an esterase inhibitor, an antioxidant, and a buffer at a pH range of about 5.7 to about 6.5 for stabilizing drugs and drug metabolites that may be present in the donor oral fluid. Interaction between the collected oral fluid and the buffer-preservative is provided by gravity drawing the collected oral fluid downward into contact with the lyophilized buffer-preservative.
    Type: Grant
    Filed: December 19, 2018
    Date of Patent: May 16, 2023
    Assignee: Research Triangle Institute
    Inventors: Robert Merrifield White, Sr., John Malcolm Mitchell, Edwin Dale Hart
  • Patent number: 11644475
    Abstract: An embodiment of the disclosure is a rack adapted to engage a rack handler. The rack includes a rack body. The rack body has a bottom, a top opposite the bottom, and a receptacle that extends from the top toward the bottom. The receptacle is sized to receive the sample collection unit. The rack body has a first interior surface that extends from the bottom toward the top, and a second interior surface that extends from the bottom toward the top. The second interior surface is opposite to the first interior surface so as to at least partially define a slot along the bottom. The rack body also includes an interference groove in the slot along at least one of the first interior surface and the second interior surface. The slot and the interference groove are sized to engage a portion of the rack handler.
    Type: Grant
    Filed: May 8, 2018
    Date of Patent: May 9, 2023
    Assignee: Siemens Healthcare Diagnostics Inc.
    Inventors: William Perry, Michael Chen, Steven Geehan, Gyula Hojer, Norbert Laszka
  • Patent number: 11624752
    Abstract: When the automatic analyzer is installed in an environment with a high altitude and different external atmospheric pressures, there is a problem that an amount of vacuum suction decreases due to a decrease in suction performance of a vacuum pump and it is difficult to perform vacuum suction of an analyzed reaction liquid. In view of the above, by newly providing a pressure adjustment mechanism within a flow path connecting a vacuum tank to vacuum pump, it possible to control the pressure difference between a pressure in the vacuum tank and an external atmospheric pressure where the analyzer is installed to be constant regardless of the installation environment. Additionally, by providing a hole in communication with the outside in the vacuum tank or a vacuum bin, it possible to control the pressure difference between the pressure in the vacuum tank and the external atmospheric pressure where the analyzer is installed to be constant regardless of the installation environment.
    Type: Grant
    Filed: February 26, 2018
    Date of Patent: April 11, 2023
    Assignee: Hitachi High-Tech Corporation
    Inventors: Tooru Inaba, Takamichi Mori, Tetsuji Kawahara
  • Patent number: 11619644
    Abstract: An analysis device employs an analysis kit including a chip provided with a capillary through which a sample flows and a cartridge superimposed on the chip and provided with a liquid reservoir. The analysis device includes a guide-in section into which the analysis kit is guided, a placement section on which the analysis kit placed so as to be supported, a pusher member that pushes the analysis kit from one side face of the analysis kit, contact members that oppose another side face on an opposite side in the horizontal direction to the one side face of the analysis kit placed on the placement section, and contact the other side face of the analysis kit being pushed in by the pusher member so as to position the analysis kit in the horizontal direction, and a measurement member that measures a component present in the sample in the analysis kit.
    Type: Grant
    Filed: August 29, 2022
    Date of Patent: April 4, 2023
    Assignee: ARKRAY, Inc.
    Inventors: Akihiro Yamamoto, Shigeru Kitamura, Naoto Shichi
  • Patent number: 11619641
    Abstract: A container carrier for carrying a sample container along a track is presented. The container carrier comprises a holding portion for receiving and holding a sample container and a base portion. A radio frequency identification (RFID) tag containing identifying information is provided with an antenna for wireless communication of the RFID tag with a reader device of the diagnostics system to read the identifying information. The RFID tag is on the holding portion. An arrangement for a diagnostics system is provided comprising container carriers and a track with a transport mechanism for moving the container carriers along a transportation lane. The transport mechanism defines a transport plane along which the container carriers move. A reader device reads the identifying information from the RFID tags. The reader device comprising a reader antenna above the transport plane to generate and emit a reader field for wireless communication with the RFID tag's antenna.
    Type: Grant
    Filed: October 21, 2020
    Date of Patent: April 4, 2023
    Assignee: Roche Diagnostics Operations, Inc.
    Inventor: Riccardo Leone Benedetti
  • Patent number: 11619642
    Abstract: The invention discloses a reaction incubation device, an immunity analyzer and a reaction incubation method. The reaction incubation device comprises a reaction unit (10), which is used for bearing and incubating a reaction container; and a transfer unit (20), which is used for removing the reaction container in and out of the reaction unit (10). The reaction unit (10) comprises a rotating device (11). The rotating device (11) is provided with an incubation position which increases a predetermined angle ? at an interval of fixed time T along with the rotating device (11). The transfer unit (20) removes the reaction container out of the incubation position according to variable incubation time ti. With the device, flexible and variable incubation time can be achieved, and the problem of complicated control, low reliability and that high-speed automation is not easy to achieve in the prior art can be solved.
    Type: Grant
    Filed: October 30, 2017
    Date of Patent: April 4, 2023
    Assignee: Shenzhen Increcare Biotech Co., Ltd.
    Inventor: Zhen Zhang
  • Patent number: 11604201
    Abstract: Disclosed is a specimen analyzer configured to perform analysis on a specimen for a plurality of measurement items, the specimen analyzer including a measurement section configured to perform a specimen measurement for measuring a measurement sample prepared from a specimen and a reagent corresponding to a measurement item, and configured to perform a quality control measurement for measuring a measurement sample prepared from a quality control substance and a reagent corresponding to a measurement item; and a controller programmed to set a quality control for each measurement item, from a quality control group that includes at least two types of quality controls selected from a first quality control in which the quality control measurement is performed at a predetermined time, a second quality control in which the quality control measurement is performed every time the specimen measurement is performed a predetermined number of times of measurement, and a third quality control in which the quality control me
    Type: Grant
    Filed: November 27, 2019
    Date of Patent: March 14, 2023
    Assignee: SYSMEX CORPORATION
    Inventor: Hiroshi Kurono
  • Patent number: 11604148
    Abstract: A device and a method of using the device for improving sensitivity, speed, and easy-to-use of a colorimetric assay of a liquid sample are provided. The device includes a first plate and a second plate, spacers, and a textured surface. The two plates each have a sample contact surface and are movable relative to each other into an open configuration or a closed configuration. The sample is deposited on one or both plates in the open configuration. Thereafter, the closed configuration is formed where the plates compress at least part of the deposited sample into a continuous layer. The textured surface is disposed on the sample contact surface of the second plate and has a textured structure that scatters light, from which an optical signal such as a colorimetric or fluorescent signal can be obtained for analyzing the sample.
    Type: Grant
    Filed: February 9, 2018
    Date of Patent: March 14, 2023
    Assignee: Essenlix Corporation
    Inventors: Stephen Y. Chou, Wei Ding, Yufan Zhang, Ji Qi
  • Patent number: 11604203
    Abstract: A pretreatment device for performing pretreatment using a liquid sucked by a probe from an inside of a septum-attached container includes: a container holding unit which has a space for accommodating the septum-attached container and is provided with a hole into which the probe is inserted with respect to a septum of the septum-attached container to be stored; an installation unit in which the container holding unit is detachably installed; and a fixing unit which fixes the container holding unit to the installation unit in a state where the container holding unit is detachably installed in the installation unit, to solve the above-described problem.
    Type: Grant
    Filed: December 18, 2019
    Date of Patent: March 14, 2023
    Assignee: SHIMADZU CORPORATION
    Inventor: Nobuhiro Hanafusa
  • Patent number: 11579156
    Abstract: A method to provide control samples for validating a diagnostic test within a laboratory system is presented. The laboratory system comprises an aliquoting device, a storage, a transport system, at least two analyzers, and a control unit. A total number of control sample aliquots and an aliquot volume for each control sample aliquot is determined based on a validation time schedule. A provided total control sample volume is aliquoted into the determined total number of control sample aliquots with the determined aliquot volumes. The generated control sample aliquots are transported to one or more of the at least two analyzers according to the validation time schedule.
    Type: Grant
    Filed: June 10, 2020
    Date of Patent: February 14, 2023
    Assignee: Roche Diagnostics Operations, Inc.
    Inventors: Michael Glauser, Urs Vollenweider
  • Patent number: 11567092
    Abstract: A system for detecting mold includes a housing defining a chamber and an opening through a surface. The system includes a movable grate for selectively covering the opening. The system includes a substrate treated to promote mold growth. The system includes a mechanism for moving the substrate to move previously unexposed portions into the chamber. The system includes a thermal control system to maintain predetermined environmental conditions in the chamber. The system includes a sensor configured to detect mold growth in the chamber. The system includes a mold suppressor to kill mold in the chamber when activated. The system includes a controller to coordinate operation of the components to detect mold growth in an environment.
    Type: Grant
    Filed: December 12, 2019
    Date of Patent: January 31, 2023
    Assignee: Robert Bosch GmbH
    Inventors: Seow Yuen Yee, Franz Laermer, Christian Peters, Ning Wang, Thomas Rocznik