Patents Examined by John W. Rollins, Jr.
  • Patent number: 4981681
    Abstract: A combination of ingredients consisting of a mixture of predetermined proportions of Purified Water, Methylparaben, Potassium Hydroxide, Hydrogenated Coconut Oil, Glycerine, Polysorbate 60, Polysorbate 80, Glyceryl Stearate (and) Laureth-23, White Wax, Stearic Acid, Cetyl Alcohol, PEG-40 Stearate, Glyceryl Stearate, Salicylic Acid, HQ Squalane, DL-Alpha Tocopherol Nicotinate, Isopropyl Myristate, EPA, Lecithin, Niacin, Vitamin B6, and Propylparaben, and said aforementioned ingredients having been found to constitute a safe method of treating psoriasis, consisting of the daily application on a person's skin on a daily bases of predetermined dosages of said ingredients.
    Type: Grant
    Filed: August 26, 1988
    Date of Patent: January 1, 1991
    Inventor: Vittorio Tosti
  • Patent number: 4868212
    Abstract: A method of treatment of atopic disorders, including eczema, asthma, allergies (especially allergic rhinitis), migraine and disorders associated with atopy including Crohn's disease, ulcerative colitis, otitis media, nephrotic syndrome, or benign breast disease, or breast or other cancer, or diabetes, or alcoholism, with effective amounts of one or more of the metabolites of linoleic acid (GLA, DGLA, AA, 22:4n-6 or 22:5n-6) and one or more of the metabolites of .alpha.-linolenic acid (18:4n-3, 20:4n-3, 20:5n-3, 22:5n-3 or 22:6n-3) are administered as such or in the form of an ester, salt, amide or other derivative convertible in the body thereto alone or in an acceptable pharmaceutical carrier or diluent.
    Type: Grant
    Filed: February 9, 1989
    Date of Patent: September 19, 1989
    Assignee: Efamol Ltd.
    Inventor: David F. Horrobin
  • Patent number: 4826827
    Abstract: Short chained ligosaccharides of high structural homogeneity constituted essentially by hexasaccharides of the formula: ##STR1## in which R represents a hydrogen atom or the --SO.sub.3.sup.31 group. These hexasaccharides have a highly selective activity on certain steps in blood coagulation and are useful as anti-thrombotic medicaments.
    Type: Grant
    Filed: March 21, 1986
    Date of Patent: May 2, 1989
    Assignee: Choay S.A.
    Inventors: Jean-Claude Lormeau, Jean Choay, Maurice Petitou
  • Patent number: 4822611
    Abstract: A method of treating allergies whereby hyposensitization to allergens to which the patient has been found to be sensitive by skin testing and history is induced by sequentially scheduled oral administration of titrated amounts of allergenic extracts in a liquid vehicle comprising defined proportions of a selected hexose monosaccharide and ethyl alcohol in water.
    Type: Grant
    Filed: December 9, 1986
    Date of Patent: April 18, 1989
    Assignee: Immunotec, Inc.
    Inventor: Jack C. Booren
  • Patent number: 4812160
    Abstract: Cyclohexenone derivative of the formula ##STR1## where A is oxygen or NOR.sup.8, where R.sup.8 is alkyl, alkenyl, alkynyl, haloalkyl or haloalkenyl, chlorothienyl or alkoxyalkylB is O, S, SO or SO.sub.2,X is hydrogen or methoxycarbonyl,R.sup.1 is hydrogen, carbonylalkyl, benzoyl or a cation,R.sup.2 is alkyl,R.sup.3 and R.sup.4 are hydroxyl, chlorine, bromine, thioalkylcarboxyl, thiocarbonylalkyl, alkylcarbonyloxy, alkoxy, or alkylthio, or R.sup.3 and R.sup.4 together epoxy,R.sup.5 and R.sup.6 are hydrogen or methyl or R.sup.5 and R.sup.6 are together methyleneoxyethylene, andR.sup.7 is hydrogen or methyl,and herbicides containing these compounds.
    Type: Grant
    Filed: December 24, 1986
    Date of Patent: March 14, 1989
    Assignee: BASF Aktiengesellschaft
    Inventors: Dieter Jahn, Michael Keil, Dieter Kolassa, Ulrich Schirmer, Bruno Wuerzer, Norbert Meyer, Johann Jung, Wilhelm Rademacher
  • Patent number: 4783484
    Abstract: A pharmaceutical composition combines a physiologically acceptable carrier with substantially uniformly sized particles of an organoiodide or organobromide which is solid at physiological tempertures, has a solubility in blood serum of less that one part per ten thousand, and has a mean particle diameter of from about 0.01 microns to about 4 microns. The method of the invention involves administering to a patient an effective amount of such particles.
    Type: Grant
    Filed: October 5, 1984
    Date of Patent: November 8, 1988
    Assignee: University of Rochester
    Inventors: Michael R. Violante, Roy T. Steigbigel
  • Patent number: 4769362
    Abstract: Lipid containing molecules and compositions, including gangliosides and omental tissue extracts had previously been found to be effective in increasing angiogenesis. It has now been found that these same materials cause increased localized perfusion in mammals. A method for providing increased perfusion, using these compositions, is presented herein.
    Type: Grant
    Filed: April 14, 1986
    Date of Patent: September 6, 1988
    Assignees: Trustees of Boston University, Angio-Medical Corporation
    Inventors: Nicholas Catsimpoolas, Robert McCluer, James Evans, Robert S. Sinn
  • Patent number: 4765981
    Abstract: Gastrointestinal disorders, especially those in the very young and the very old which are manifested by nausea, vomiting, diarrhea, increased flatus, cramping, and the like, are treated by the oral administration to the patient of a therapeutically-effective amount of an aqueous extract of oatmeal. This extract is especially effective in the treatment of infant colic and infant intolerance of milk and synthetic formulas.
    Type: Grant
    Filed: October 15, 1984
    Date of Patent: August 23, 1988
    Inventor: Anna M. Joseph
  • Patent number: 4749572
    Abstract: A pharmaceutical preparation for the treatment of, e.g. ulcers, burns and skin diseases contains, as essential ingredients, from 5 to 25% by weight of Peru Balsam and from 0.01 to 0.20% by weight of silver nitrate. The preparation may be administered enterally or topically.
    Type: Grant
    Filed: August 21, 1985
    Date of Patent: June 7, 1988
    Assignee: Pharmaceutical Holdings Limited
    Inventor: Mahmoud Ahari
  • Patent number: 4748022
    Abstract: A composition and method of use for the treatment of pain and inflammation associated with lesions of the skin or mucus membrane, such as herpes simplex, herpes labialis, herpes progenitalis, chickenpox lesions, herpes genitalis, sensitivity of gingival tissue due to procedures for etching teeth with HCl, swollen gums, cheilosis, oral traumatic injuries, aphthous ulcer, by applying to the lesion an effective amount of a topical composition comprising diphenhydramine HCl, lidocaine HCl, aloe vera gel, propolis and sufficient base to raise the pH to 8-9.
    Type: Grant
    Filed: December 9, 1986
    Date of Patent: May 31, 1988
    Inventor: John A. Busciglio
  • Patent number: 4748159
    Abstract: Disclosed is a method for the treatment of hyperglycemia, hyperlipemia, inflammatory diseases, pains due to the accentuation of central nerve, pyrexia due to the accentuation of central nerve or tumor, which comprises administering to a patient suffering therefrom a pharmaceutically effective amount of p-aminobenzoic acid-N-L-rhamnoside or a pharmaceutically acceptable salt thereof.
    Type: Grant
    Filed: November 24, 1986
    Date of Patent: May 31, 1988
    Assignee: Kureha Kagaku Kogyo Kabushiki Kaisha
    Inventors: Chikao Yoshikumi, Yoshio Ohmura, Fumio Hirose, Masanori Ikuzawa, Kenichi Matsunaga, Takayoshi Fujii, Minoru Ohhara, Takao Ando
  • Patent number: 4746516
    Abstract: A method is disclosed for purifying non-homogeneous systems, known as liposomic suspensions, from non-entrapped drugs wherein said suspensions are treated with liquid or solid polymers of synthetic and organic nature having chemical functionality, which are used as ion-exchangers. The liquid or solid polymers are based on styrene, divinylbenzene, acrylic acid, methacrylic acid, and the like, normally known as ion-exchange resins, and may include carboxylic, phosphonic or sulphonic functions of different matrices. The ion-exchange resins may also include salified quaternary ammonium, primary, secondary and tertiary amminic or phosphinic functions or other functions with different matrices, including phenolformaldehyde, styrene-divinylbenzene, acrylates, methacrylates, hydrocarbons and condensation-resins.
    Type: Grant
    Filed: October 22, 1986
    Date of Patent: May 24, 1988
    Assignee: Farmitalia Carlo Erba S.p.A.
    Inventors: Luigi Moro, Guido Neri, Alessandro Rigamonti
  • Patent number: 4742066
    Abstract: Skin treatment compositions are provided which inhibit generation of free radicals in the skin and which include 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid, 6-ethoxy-1,2-dihydro-2,2,4-trimethyl quinoline or mixture thereof.
    Type: Grant
    Filed: March 17, 1986
    Date of Patent: May 3, 1988
    Assignee: Charles of the Ritz Group Ltd.
    Inventors: George E. Deckner, Arthur C. W. Georgalas
  • Patent number: 4742054
    Abstract: A method, and compositions, for treating an animal with an injured spinal cord, causing loss to sensory function and motor control, to regain such function and control. The method comprises the administration of at least 1 .alpha..sub.2 -adrenergic receptor agonist or a serotonergic receptor agonist or a dopaminergic receptor agonist, and preferably a combination with an anti-desensitization agent, such as a xanthine, a .beta.-adrenergic receptor agonist or a vascular skeletal muscle dilator. The composition comprises at least 1 receptor agonist and a second compound acting in conjunction therewith or preventing desensitization thereof.
    Type: Grant
    Filed: January 16, 1985
    Date of Patent: May 3, 1988
    Inventor: Nosrat E. Naftchi
  • Patent number: 4737362
    Abstract: A hair treatment composition containing, as an effective ingredient, lipase. This hair treatment composition can effectively prevent the generation of dandruff and itching and can also effectively accelerate the growth of hair.
    Type: Grant
    Filed: September 7, 1984
    Date of Patent: April 12, 1988
    Assignee: Suntory Limited
    Inventors: Hajime Yoshizumi, Teruo Amachi, Takaaki Kusumi, Takaharu Tanaka, Hiroshi Ishigooka
  • Patent number: 4732759
    Abstract: A bath preparations comprise a cyclodextrin clathrate compound of vitamin, saccharifying enzyme and other materials of baths. The vitamin may be selected from the group consisting of vitamin A, vitamin B, vitamin C, Vitamin D, vitamin E, vitamin F and vitamin P. The saccharifying enzyme may be mixed with the cyclodextrin clathrate compound of the vitamin or may be insulated from the cyclodextrin clathrate compound of the vitamin.Method for producing bath preparations comprises contacting vitamin with cyclodextrin to form a cyclodextrin clathrate compound of the vitamin and mixing the cyclodextrin clathrate compound of the vitamin with saccharifying enzyme and other raw materials of baths.
    Type: Grant
    Filed: February 24, 1986
    Date of Patent: March 22, 1988
    Assignee: Japan Liquid Crystal Co., Ltd.
    Inventors: Ichiro Shibanai, Kenji Nakamura
  • Patent number: 4732889
    Abstract: A pharmaceutical composition for the treatment of the anemia of rheumatoid arthritis comprising a therapeutically effective amount of human erythropoietin (EPO) in a parenterally acceptable vehicle is disclosed. Human EPO may be extracted from human urine or also be prepared by expressing in a host cell the gene coding for the amino acid sequence of human EPO.
    Type: Grant
    Filed: February 3, 1986
    Date of Patent: March 22, 1988
    Assignee: Chugai Seiyaku Kabushiki Kaisha
    Inventors: Osamu Cynshi, Koji Mizuno
  • Patent number: 4731246
    Abstract: There is provided a palatable pre-mixed bran drink comprising heat treated, degelled bran in the presence of hydrated colloidal magnesium aluminum silicate and an acidification agent. The drink has good mouthfeel and may be used as a bulk supplement to diet.
    Type: Grant
    Filed: October 31, 1985
    Date of Patent: March 15, 1988
    Assignee: Product Resources International, Inc.
    Inventors: Leonard Chavkin, Leonard Mackles
  • Patent number: 4731241
    Abstract: A percutaneous pharmaceutical preparation for external use containing N-ethoxycarbonyl-3-morpholinosydnonimine (molsidomine) and an absorption promoter selected from the group consisting of aliphatic monoalcohols of 10 to 22 carbon atoms, aliphatic monoamides of 8 to 18 carbon atoms and aliphatic monoamines of 10 to 16 carbon atoms gives a high blood concentration of molsidomine over a long time period when applied onto the human skin.
    Type: Grant
    Filed: March 9, 1987
    Date of Patent: March 15, 1988
    Assignee: Takeda Chemical Industries, Ltd.
    Inventors: Masayuki Yamada, Yoshiaki Uda
  • Patent number: 4731379
    Abstract: A flea eradicator consists essentialy of 1.7 percent by weight dioctyl sodium sulfosuccinate and 0.3 percent by weight sodium benzoate in water. The composition is topically applied and kills fleas substantially more quickly than do conventional flea soaps. The use of dioctyl sodium sulfosuccinate avoids thre problems of malodorous soaps, toxic insecticides and alkalin harshness usually associated with flea soaps. The need to incorporate polyethylene glycol or lanolin in the flea eradicator is thereby eliminated, as is the need for any other toxic insecticide. The use of sodium benzoate appears to promote healing of the infested area.
    Type: Grant
    Filed: June 5, 1985
    Date of Patent: March 15, 1988
    Assignee: H.S.C. Corporation
    Inventor: Jack S. Panzer