Abstract: An ophthalmological patient interface apparatus (4), having a coupling apparatus (41) for mechanically coupling to an application head (3) of an ophthalmological laser system (10), comprises a lens-element system (44) which is arranged between the eye (2) and the application head (3) in the state coupled to the application head (3) during the treatment of an eye (2), said lens-element system being coupled into the beam path from the projection lens (30) to the eye (2). The lens-element system (44) is configured to image a first focal area (B) of the projection lens (30) disposed upstream of the lens-element system (44) in the beam path onto a second focal area (B*) in the eye (2) disposed downstream of the lens-element system (44) in the beam path, in such a way that a laser beam (L) focussed onto the first focal area (B) by the projection lens (30) causes tissue processing in the second focal area (B*) in the eye (2).

Abstract: A medical device and medical device system for delivering left ventricular pacing that includes a subcutaneous sensing device having a subcutaneous electrode to sense a subcutaneous cardiac signal and an emitting device to emit a trigger signal in response to the sensed cardiac signal, an intracardiac therapy delivery device to deliver the left ventricular pacing in response to the emitted trigger signal, and a processor configured to determine whether the medical device system is in one of a VVD pacing mode and a VVI pacing mode, determine whether the delivered left ventricular pacing captures the left ventricle, determine whether to adjust a pacing parameter in response to the determination of whether the device system is in one of a VVD pacing mode and a VVI pacing mode and the determination of whether the delivered left ventricular pacing captures the left ventricle, and deliver the left ventricular pacing in response to determining whether to adjust the pacing parameter.

Abstract: An implantable medical device (IMD) includes a tap sensor configured to detect an impact event occurring on the surface of the patient's body. The tap sensor is configured to determine whether the impact event (which may be, for example, a tap of a finger or hand upon a surface of the body) likely is a communication directed at the tap sensor. In response to determining that the impact event likely is a communication directed at the tap sensor, the IMD is configured to transition from a first state to a second state.

Abstract: The invention comprises an apparatus and method of use thereof for using a single patient position during, optionally simultaneous, X-ray imaging and positively charged particle imaging, where imaging a tumor of a patient using X-rays and positively charged particles comprises the steps of: (1) generating an X-ray image using the X-rays directed from an X-ray source, through the patient, and to an X-ray detector, (2) generating a positively charged particle image: (a) using the positively charged particles directed from an exit nozzle, through the patient, through the X-ray detector, and to a scintillator, the scintillator emitting photons when struck by the positively charged particles and (b) generating the positively charged particle image of the tumor using a photon detector configured to detect the emitted photons, where the X-ray detector maintains a position between said the nozzle and the scintillator during the step of generating a positively charged particle image.

Abstract: An example probe multi-spot, multi-fiber, laser probe includes a plurality of optical fibers extending from a proximal end of the laser probe to at least near a distal end of the laser probe, and a cannula having a distal end and surrounding the plurality of optical fibers along at least a portion of the laser probe at or near the distal end of the laser probe. A distal pass-through element is positioned within the cannula and at or near the distal end of the cannula and has a groove and/or channel corresponding to each fiber and through which a respective optical fiber passes, and is formed so as to induce a radial rotation of each of the plurality of optical fibers, relative to a central longitudinal axis of the cannula, as the respective optical fiber passes through the distal pass-through element.

Abstract: A computing device executes a software program that communicates various deep brain stimulation (DBS) routines to a neurostimulator. The software program generates a graphical user interface (GUI) that receives inputs that are indicative of a patient's response to the various DBS routines. The GUI further includes a representation of each of one or more electrode leads that are connected to the neurostimulator. Based on the patient response inputs, one or more symbols that are indicative of an effectiveness of the stimulation routines are displayed at positions on the lead representations that correspond to parameters of the stimulation routines.

Abstract: Systems and methods for reducing ventricle filling volume are disclosed. In some embodiments, a stimulation circuit may be used to stimulate a patient's heart to reduce ventricle filling volume or even blood pressure. When the heart is stimulated at a consistent rate to reduce blood pressure, the cardiovascular system may over time adapt to the stimulation and revert back to the higher blood pressure. In some embodiments, the stimulation pattern may be configured to be inconsistent such that the adaptation response of the heart is reduced or even prevented. In some embodiments, a stimulation circuit may be used to stimulate a patient's heart to cause at least a portion of an atrial contraction to occur while the atrioventricular valve is closed. Such an atrial contraction may deposit less blood into the corresponding ventricle than when the atrioventricular valve is opened throughout an atrial contraction.

Abstract: A patient monitoring apparatus and method is provided. A plurality of moving average filters each receive a signal sensed from a patient and generates an output signal including a respective cutoff frequency. An extraction processor is coupled to receive the sensed signal and output signals from each moving average filters. The extraction processor determines at least one feature associated with the sensed signal based on at least one of the sensed signal and the output signals from each moving average filter and generates a feature signal including data representative of the determined at least one feature. A classification processor identifies a position of artifacts within the sensed signal based on the feature signal and generates a signal identifying the position of the artifacts.

Abstract: A probe, system, and method of capacitive sensing for detection of relative rotation of one tube with respect to a fixed tube of a probe is provided herewith. The probe includes an inner core, a concentric cylindrical tube, and at least one inner electrode fixed to the inner core and at least one outer electrode fixed to the cylindrical tube. The electrodes are rotationally aligned and form a capacitive sensor that can sense the rotation angle of the inner core compared to the cylindrical tube. This ability to sense relative rotation angle can be used to detect and/or correct for non-uniform rotational distortion.

Abstract: An implantable or other ambulatory medical apparatus comprises a posture sensing circuit, a physiologic sensing circuit that senses a time varying physiologic signal, and a processor circuit. The processor circuit includes a posture calculation circuit and a measurement circuit. The posture calculation circuit determines a posture of the subject using posture data obtained using the posture signal and determines when the posture of the subject is steady state. The measurement circuit derives a physiologic measurement using physiologic data extracted from the physiologic signal during at least one time period when posture is determined to be steady state and provides the physiologic measurement to at least one of a user and a process in association with the determined steady state posture.

Abstract: A method for providing electrical stimulation to a user as a user performs a set of tasks during a time window, the method comprising: providing an electrical stimulation treatment, characterized by a stimulation parameter and a set of portions, to a brain region of the user in association with the time window; for each task of the set of tasks: receiving a signal stream characterizing a neurological state of the user; from the signal stream, identifying a neurological signature characterizing the neurological state associated with the task; and modulating the electrical stimulation treatment provided to the brain region of the user based upon the neurological signature, wherein modulating comprises delivering a portion of the set of portions of the electrical stimulation treatment to the brain region of the user, while maintaining an aggregate amount of the stimulation parameter of the treatment provided during the time window below a maximum limit.

Abstract: An electronic module for a system for neural applications comprising a housing and a filtering element that form a closed, miniaturized Faraday cage a corresponding lead, active lead can, a controller and systems.

Abstract: An Implantable Pulse Generator (IPG) operable as a Deep Brain Stimulator (DBS) is disclosed which is mountable to the skull of a DBS patient, and which therefore is much closer to the site of intended therapy. The IPG includes an electronics section, a charging coil section, a connector block section configured to connect to the proximal end of implanted leads, and an electrode wire section connecting the connector block section to the electronics section. The electronic section includes a housing that is positionable into a hole formed in the patient's skull. Once so positioned, the housing may be affixed to the skull via bone screws. The charging coil section may be separate from and non-overlapping with the electronics section, or the charging coil section may encircle the electronics section.

Abstract: The present invention is a flexible circuit electrode array for neural stimulation including a polymer base layer, a metal trace layer on the polymer base layer, and a polymer top layer on the metal traces layer, where the metal trace layer forms at least one electrode made of multiple smaller common electrodes connected by electrical traces.

Abstract: A method, programmer for a neurostimulator, and neurostimulation kit are provided. The kit comprises a neurostimulator, and a plurality of elongated lead bodies configured for being coupled to the neurostimulator, each having a plurality of proximal contacts and a plurality of distal electrodes respectively electrically coupled to the proximal contacts, wherein an in-line connectivity between the electrodes and proximal contacts carried by the different lead bodies differs from each other. Electrical energy is conveyed between the electrodes of the selected lead body and the tissue, an electrical fingerprint is measured at the proximal contacts of the selected lead body in response to the conveyed electrical energy, and the selected lead body is identified based on the measured electrical fingerprint. These steps can be performed by the programmer.

Abstract: Accurate and effective methods for measuring cardiovascular and respiratory parameters are provided. The method for deriving a depth-specific photoplethysmography (PPG) signal from multi-wavelength PPG signals includes choosing light wavelength combinations, calibrating a multi-layer light-tissue interaction model referring to a physiological signal, and generating the depth-specific PPG signal from the multi-wavelength PPG signals based on the calibrated light-tissue interaction model. The disclosed method for cuff-less blood pressure measurement includes recording a physiological signal and multi-wavelength PPG signals of a predetermined body part, deriving the depth-specific PPG signal reflecting the arterial blood volume with the physiological signal as a reference, calculating the pulse transit time (PTT) from the physiological signal and the derived arterial blood PPG signal, and calculating the blood pressure from the calibrated PTT and blood pressure relationship.

Abstract: The present disclosure relates generally to electronic devices and methods for sensor signal collection. The electronic devices may include retroreflectors for redirecting scattered light back to the photodetector. The retroreflectors may be positioned at various locations on or in the electronic device, and may employ various geometric elements having retroreflective capability.

Abstract: A cardiac pacemaker is disclosed for pacing cardiac tissue to improve synchrony between the atria and ventricles and/or between the left and right ventricles. A pulse generator is configured to deliver a pacing pulse to a patient's ventricle at an atrioventricular (AV) delay following a preceding atrial event. A sensing circuitry configured to sense a signal from the patient's ventricle following delivery of a said pacing pulse. A processing circuitry coupled to the pulse generator and the sensing circuitry and configured to control the pulse generator, the processing circuitry further configured to: (1) acquire from the sensed signal a set of features; (2) determine whether the ventricular pacing pulse effectively captures the patient's ventricle using the set of features; (3) determine whether one or more tissue latency conditions are present. The one or more pacing pulse parameters are adjusted, in response to determining that tissue latency is present.

Abstract: Provided is a Coupled Domain Sensor (CDS) that can be used to, for example, evaluate hydration and occlusion of blood in patients with edema using electrical and optical measurements. Advantageously, the CDS provides a quicker, more effective and accurate way of monitoring this medical condition.

Abstract: A therapy delivery element configured for at least partial insertion in a living body. A braided structure surrounds the conductor assembly. A distal end of the braided structure is attached to an electrode assembly and a free floating proximal end is located near a connector assembly. An outer tubing surrounds the braided structure. The outer tubing includes a proximal end attached to the connector assembly and a distal end attached to the braided structure near the electrode assembly. A proximal tension force applied to the connector assembly acts substantially on the outer tubing and the conductor assembly and a proximal tension force applied to the free floating proximal end acts substantially on the braided structure.