Patents Examined by Jospeh McKane
  • Thiazole compounds and methods of modulating signal transduction
    Patent number: 6080772
    Abstract: The present invention relates to thiazole containing compounds capable of inhibiting protein tyrosine phosphatase activity. The invention further relates to the use of such compounds to modulate or regulate signal transduction by inhibiting protein tyrosine phosphatase activity. Finally, the invention relates to the use of such compounds to treat various disease states including diabetes mellitus.
    Type: Grant
    Filed: December 11, 1997
    Date of Patent: June 27, 2000
    Assignee: Sugen, Inc.
    Inventors: Peng Cho Tang, John Yudhistir Ramphal, G. Davis Harris, Jr., Asaad S. Nematalla
  • Circulatory disorder improving agent
    Patent number: 5691339
    Abstract: A circulatory disorder improving agent comprising, as an active ingredient, a dihydropyridine derivative of the formula (I) ##STR1## or an acid addition salt thereof. Said circulatory disorder improving agent is particularly useful as an organ circulation disorder improving agent or peripheral circulation improving agent.
    Type: Grant
    Filed: April 21, 1995
    Date of Patent: November 25, 1997
    Assignee: The Green Cross Corporation
    Inventors: Hiroshi Shinyama, Toru Kawamura, Minori Okita, Takeshi Uchida, Masahiro Watanabe