Abstract: A modular medical device system comprises a parent module with a proximal end configured to remain outside the body of a patient and a distal end configured to go inside the body of a patient, the distal end comprising an inner lumen; and an adapter module comprising a proximal portion and a distal portion, an attachment mechanism positioned at the proximal portion and comprising an interfacing element and an elongated element, wherein at least a portion of the interfacing element compresses to engage the inner lumen of the parent module, and wherein the elongated element connects the attachment mechanism to the distal portion of the adapter module.

Abstract: A method for performing an intravascular procedure includes inserting a guide catheter into a blood vessel, and passing a device guide through the guide catheter so that a distal portion of the device guide, having a semi-tubular shape, protrudes from a distal end of the guide catheter into the blood vessel. An intravascular device is inserted through the guide catheter via the distal portion of the device guide to a target site in the blood vessel.

Abstract: A morselizer has a first end section with an axially and radially hollow luer fitting, a second end section with an axially and radially hollow luer fitting, a housing juxtaposed therebetween, a channel extending axially between the first end section and the second end section and through the housing providing an axial liquid pathway therein, and at least one blade disposed within the housing. Each end of the morselizer is attachable to a structure with a complimentarily sized luer fitting. In an embodiment, the morselizer facilitates atraumatic resizing of material through axial liquid transfer, by transferring material from a first structure attached to the first end section, thence through the channel, where material is resized by the blade, and through the second end section to a second structure attached to the second end section. The resized material may be suitable for injection, such as through a fine needle.

Abstract: The present disclosure relates to a drug delivery device, having a longitudinal axis and comprising a plunger movable along the longitudinal axis and a guide curve adapted to engage at least one part of the plunger so as to guide the plunger when the plunger is being released to move along the longitudinal axis.

Abstract: A medication delivery patch that is applied to the skin and activated to deliver a medication or other fluid into or through the skin. The patch may be completely mechanically driven, with no electronic components, for low cost, safety, and reliability. Pressing an activation button may set in motion a sequence of mechanical events that result in a needle exiting the patch into the skin of the user, and flow of fluid from an internal pouch in the patch into the user. When delivery is complete, another sequence of mechanical events may occur to retract the needle from the skin and stop the flow of fluid, and to show a visible indicator that delivery is complete. The patch may contain a fluid channel, such as a microfluidic channel, that controls the rate and time of delivery; this channel can be configured or selected for different medications or use cases.

Abstract: Microneedle patches and systems, and methods for use of such patches and systems. In one aspect, a microneedle patch is provided including a tab portion for handling the microneedle patch. In another aspect, a system is provided including a microneedle patch and a tray for housing the microneedle patch. In still another aspect, various indicators providing for providing feedback prior to, during, and after administration of the microneedle patch are provided. Advantageously, the described microneedle patches and systems provide improved handling and ease of application of the microneedle patches to skin for the delivery of therapeutic agents.

Abstract: Systems and methods for delayed delivery of a drug are disclosed. A drug delivery system may include a delivery member for insertion into a patient and a reservoir configured to receive a volume of a drug. An energy source may be activatable by the patient to actuate the reservoir to deliver the drug to the patient as a single bolus. A lockout system may be configured to have a locked state, wherein the lockout system prevents movement of the delivery member and/or activation of the energy source, and an unlocked state, wherein the lockout system permits movement of the delivery member and/or activation of the energy source. The lockout system may be configured to automatically change from the locked state to the unlocked state after a preselected time period has elapsed. An output element may generate a detectable output after the preselected time period has elapsed for notifying the patient.

Abstract: Disclosed is a syringe for a micro-dosing syringe pump. The syringe includes a reservoir having an outlet port; a plunger having a track, with the plunger received inside a portion of the reservoir; a plunger driver comprising a gear connected to one end of a shaft and a pin located adjacent an opposite end of the shaft, with the plunger driver received inside the plunger and with the pin located inside and engaging the track. In use, rotation of the gear in a first direction advances the plunger into the reservoir a first distance as the pin travels in the track and rotation of the gear in a second direction opposite the first direction advances the plunger a further distance into the reservoir as the pin travels in the track. The design prevents excess dosing in a runaway motor failure.

Abstract: Medical devices and methods for making and using medical devices are disclosed. An example medical device may include a guide extension catheter. The guide extension catheter may include a proximal member having a proximal end, a distal end, and a proximal diameter. The guide extension catheter may additionally include a collar member attached to the distal end of the proximal member, the collar member comprising a base portion and one or more ribs connected to the base portion and extending distally away from the base portion. In still some additional embodiments, the guide extension catheter may further include a distal sheath member attached to the collar member, the distal sheath member having a distal diameter larger than the proximal diameter.

Abstract: An assembly machine for assembling a rigid needle guard (10) having an inner part (11) made of elastomeric material, and a rigid outer body (12) that is fastened to the inner part (11) made of elastomeric material via a folded-in portion (121) of the bottom axial end of the rigid outer body (12). The folded-in portion (121) extends radially inwards from the outer peripheral surface (125) of the rigid outer body (12), the outer surface of the folded-in portion (121) forming, at its axially-bottom and radially-outer edge, a sharp and acute angle relative to the outer peripheral surface (125) of the rigid outer body (12).

Abstract: A packaging device for a trocar assembly includes a trocar packaging clip having at least two holding structures configured to be detachably secured to the proximal portions of the trocar obturator and the cannula for retention of the trocar obturator and cannula relative to each other. The trocar packaging clip includes an anti-rotation structure configured to engage at least one of the trocar and the cannula to prevent relative rotation thereof.

Abstract: A syringe and needle hub for a syringe has distal patient-facing side having a surface for contact with the subject's skin during injection. The contact surface is formed by a distal face of a post supporting a cannula and an outer collar surrounding the post. The axial distance between the distal face of the post and the distal face of the collar provided a contact surface with a radius of curvature to control the desired injection. The syringe barrel can have finger flanges extending outwardly where the flanges have a tactile member such as a dimple projecting from a proximal face of the flange and recess in a distal face of the flange.

Abstract: A system determines the location of a tip of a hypodermic needle by moving a needle along a path, shining light from two sources onto respective portions of the path, and analysing signals received from the respective light sources that have been reflected by the needle.

Abstract: A fluid infusion device includes a housing having a reservoir chamber that receives a fluid reservoir. The fluid reservoir has a first end and a second end. The fluid infusion device includes a connector system having a first body section coupled to a second body section. The first body section defines a bore in communication with a chamber and a counterbore of the second body section to define a fluid flow path. The chamber of the second body section is in fluid communication with a vent subsystem defined through the second body section. The vent subsystem terminates in an outlet, and the vent subsystem is to direct gas in the fluid flow path through the second body section to the outlet. The fluid infusion device includes at least one ring disposed within the reservoir chamber that cooperates with the connector system to securely couple the connector system to the housing.

Abstract: A venous access port assembly having a housing base with a discharge stem, a cap, and an interior reservoir. The port assembly is provided with X-ray discernable indicia to identify an attribute of the assembly after its implantation and clearly appear on an X-ray of the patient in a manner informing the radiologist or technologist and the medical practitioner of that particular attribute. The indicia are cuts in a reservoir lining of radiopaque material such as metal where the cuts having narrow slot width are in the form of one or more sets of alphabetical letters such as “CT” in the lining's side wall or bottom wall.

Abstract: A medicament delivery device system for delivery of a medicament from a cartridge (10). The system comprises a first container (11) for storage of a first substance, a second container (12) received in the first container (11) for storage of a second substance, and valve means (68) for closing a distal end of the second container (12). The system further comprises a disposable cassette (102) and a reusable firing unit (200). The cassette (102) has a body (104) for receiving the cartridge (10), and a mixing element (148) for displacing the second substance into the first chamber (16) in a mixing stroke, to mix with the first substance to form the medicament. The firing unit (200) comprises a drive element (208) for expelling the medicament from the first chamber (16) in a delivery stroke and a trigger arrangement (240) for initiating the delivery stroke.

Abstract: The invention discloses a sterile syringe (100) comprising a barrel (1) having internal surfaces (2), a plunger (3) movable within the barrel, a non-sliding seal (7) between the barrel and the plunger defining a sealed volume (8) and at least one filter (9) allowing only filtered gases to enter the sealed volume such that the syringe maintains its sterility even after several uses. The filters could be positioned on different locations on the syringe like on the non-sliding seal, the barrel, the barrel flange or the plunger handle.

Abstract: An assembly for a medication delivery device having a body, a piston rod and a setting nut. The piston rod is rotatable relative to the body in a dose setting state and is axially movable in a distal direction with respect to the body in a dose delivering state. The setting nut is secured against rotational movement with respect to the body, but is axially movable relative to the body, being helically coupled with the piston rod to axially travel in the proximal direction for setting a dose of a medication due to a helical movement of the setting nut with respect to the piston rod when the piston rod is rotated in the dose setting state, and is able to axially travel in the distal direction for delivering the set dose of the medication when the piston rod is axially moved in the dose delivering state of the assembly.

Abstract: A support structure for a medicament container is disclosed that is arranged to accommodate an elongated plunger rod, where the support structure has at least one flexible element arranged to be moved in contact with, and to exert a force, on a distal end surface of the medicament container, wherein the at least one flexible element is provided with a contact member arranged to contact an outer surface of the plunger rod and to be moved out of contact with the plunger rod when moved in contact with the medicament container.

Abstract: Provided is an epidural device configured to inhibit or substantially or completely prevent further progression of an epidural needle upon entry of the needle into the epidural space. When the needle is inserted into the ligamentum of the patient's back, the device may be pressurized with fluid using the resistance of the dense ligament to maintain pressure. This pressurization may lock a pushing mechanism in place relative to the needle such that the pushing mechanism can be used to advance the needle. Once the epidural space is reached, the fluid (e.g., saline or air) enters the epidural space, and the release of pressure may cause the trigger mechanism to disengage from the sliding pusher, allowing the pusher to slide along the body of the construct. The device thus may provide the ability to detect the epidural space using pressure loss while preventing the needle from advancing into the dura once the space is reached.