Patents Examined by Karen E. Toth
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Patent number: 11564569Abstract: An implantable intraocular physiological sensor for measuring intraocular pressure, glucose concentration in the aqueous humor, and other physiological characteristics. The implantable intraocular physiological sensor may be at least partially powered by a fuel cell, such as an electrochemical glucose fuel cell. The implantable intraocular physiological sensor may wirelessly transmit measurements to an external device. In addition, the implantable intraocular physiological sensor may incorporate aqueous drainage and/or drug delivery features.Type: GrantFiled: July 11, 2018Date of Patent: January 31, 2023Assignee: GLAUKOS CORPORATIONInventors: Thomas W. Burns, Harold A. Heitzmann, Kenneth Martin Curry, David S. Haffner, David Applegate, Bruce Nogales
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Patent number: 11547331Abstract: The present disclosure relates to optical methods and devices based on pulsate behavior of blood and optical absorption spectroscopy to measure the level of water and/or other substances or compounds, such as an alcohol or lipid, in the blood and the tissues surrounding blood vessels and arteries.Type: GrantFiled: August 10, 2016Date of Patent: January 10, 2023Inventor: Mohsen Sharifzadeh
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Patent number: 11510595Abstract: An implantable sensor can be used for determining a concentration of at least one analyte in a medium, particularly in a body tissue and/or a body fluid. The implantable sensor can comprise a flexible, tubular sensor element. This sensor element has a tubular body on which at least two electrode rings are mounted for electrochemical determination of the concentration of the analyte.Type: GrantFiled: November 3, 2009Date of Patent: November 29, 2022Assignee: Roche Diabetes Care, Inc.Inventors: Karin Schwind, Hans-Peter Haar, Otto Fuerst
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Patent number: 11484283Abstract: Described herein are a computer enhanced medical method and device for generating an asthmatic condition indication. The apparatus receives a lung signal from a stethoscope, the lung signal having been converted from an analog signal to a digital signal. Furthermore, circuitry included in the apparatus performs, inter alia, the following: displays a patient recording canvas corresponding to physical locations on a body of the patient, the canvas including an anterior patient orientation and a posterior patient orientation, generates a recording process, the recording process including recording, for a predetermined period of time, the detected lung signal, and associates the recording with a marked location. Furthermore, the circuitry merges the recorded lung signal from each marked location on the patent recording canvas as merged information, and applies processing to the merged information to generate the asthmatic condition indication.Type: GrantFiled: December 4, 2017Date of Patent: November 1, 2022Assignee: CHILDREN'S NATIONAL MEDICAL CENTERInventors: Raj Shekhar, Sukryool Kang, Stephen Teach, Shilpa Patel, Dinesh Pillai
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Patent number: 11478173Abstract: A method of calibrating an analyte measurement system is provided.Type: GrantFiled: October 4, 2018Date of Patent: October 25, 2022Assignee: Abbott Diabetes Care Inc.Inventors: Marc Barry Taub, Wesley Scott Harper, Glenn Howard Berman, Jean Mei Huang
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Patent number: 11457869Abstract: Method and apparatus for providing an integrated transmitter unit and sensor insertion mechanism is provided.Type: GrantFiled: December 21, 2018Date of Patent: October 4, 2022Assignee: ABBOTT DIABETES CARE INC.Inventor: Gary Ashley Stafford
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Patent number: 11460430Abstract: Biological chemicals, potentially found in blood are measured by collecting sweat and determining the concentration or meaning of the selected chemical in sweat. The sweat can be collected using a time based, interval collector and analyzed using an external device. It can also be collected on a one time basis, using a flexible, chemical capacitor, or on a continuous basis using a chemical, field effect transducer.Type: GrantFiled: April 3, 2013Date of Patent: October 4, 2022Assignee: University Of CincinnatiInventors: Joshua A. Hagen, Jason Charles Heikenfeld, Ian Papautsky, Linlin Hou, Rajesh Naik, Nancy Kelley-Loughnane, Morley O. Stone, John Busbee, Xiao Wang
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Patent number: 11457900Abstract: The invention relates to a device for capture of cellular biomarkers circulating in an animal or human biological flow, characterised in that it is suitable for use in vivo and in that it comprises a means of filtration intended to retain the said cellular biomarkers, the said means of filtration comprising at least one through-aperture the dimensions of which are suitable for retaining the said cellular biomarkers and being integral with a support, the support taking the form of a hollow component.Type: GrantFiled: February 2, 2016Date of Patent: October 4, 2022Assignees: Centre National de la Recherche Scientifique, Centre Hospitalier Universitaire de Toulouse, Universite Toulouse III—Paul SabatierInventors: Aline Cerf, Sylvain Sanson, Hélène Cayron, Alejandro Kayum Jimenez, Christophe Vieu, Bernard Malavaud
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Patent number: 11452468Abstract: A monitoring system for cardiac operations with cardiopulmonary bypass comprising: a processor operatively connected to a heart-lung machine; a pump flow detecting device connected to a pump of the heart-lung machine to continuously measure the pump flow value and send it to the processor; a hematocrit reading device inserted inside the arterial or venous line of the heart-lung machine to continuously measure the blood hematocrit value and to send it to the processor; a data input device to allow the operator to manually input data regarding the arterial oxygen saturation and the arterial oxygen tension; computing means integrated in the processor to compute the oxygen delivery value on the basis of the measured pump flow, the measured hematocrit value, the preset value of arterial oxygen saturation, and the preset value of arterial oxygen tension; and a display connected to the processor to display in real-time the computed oxygen delivery value.Type: GrantFiled: December 6, 2018Date of Patent: September 27, 2022Assignee: Sorin Group Italia S.r.l.Inventor: Marco Ranucci
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Patent number: 11412936Abstract: Systems and apparatus are included that are configured to determine the effectiveness of apparatus and methods used to diagnose and unblock microvascular obstruction (MVO). An infusion system blocks antegrade flow for a short time and measures vascular pressure response as an infusate is infused in stepwise fashion at increasingly higher flowrates. During the antegrade flow occlusion, calculations of the real-time vascular resistance can be obtained using the formula R(t)=P(t)/Qmean(t) where: Qmean (t) is the flow mean values generated by the infusion system; P(t) is the distal pressure response in the vessel generated from the flow infusion; and R(t) is the calculated vascular resistance using the two other known parameters.Type: GrantFiled: September 19, 2018Date of Patent: August 16, 2022Assignee: CorFlow Therapeutics AGInventors: Jon Helge Hoem, Robert S. Schwartz, Martin T. Rothman
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Patent number: 11399722Abstract: A plethysmographic respiration processor is responsive to respiratory effects appearing on a blood volume waveform and the corresponding detected intensity waveform measured with an optical sensor at a blood perfused peripheral tissue site so as to provide a measurement of respiration rate. A preprocessor identifies a windowed pleth corresponding to a physiologically acceptable series of plethysmograph waveform pulses. Multiple processors derive different parameters responsive to particular respiratory effects on the windowed pleth. Decision logic determines a respiration rate based upon at least a portion of these parameters.Type: GrantFiled: August 31, 2018Date of Patent: August 2, 2022Assignee: MASIMO CORPORATIONInventors: Ammar Al-Ali, Anmol Majmudar
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Patent number: 11363951Abstract: An implantable intraocular physiological sensor for measuring intraocular pressure, glucose concentration in the aqueous humor, and other physiological characteristics. The implantable intraocular physiological sensor may be at least partially powered by a fuel cell, such as an electrochemical glucose fuel cell. The implantable intraocular physiological sensor may wirelessly transmit measurements to an external device. In addition, the implantable intraocular physiological sensor may incorporate aqueous drainage and/or drug delivery features.Type: GrantFiled: September 12, 2012Date of Patent: June 21, 2022Assignee: GLAUKOS CORPORATIONInventors: Thomas W. Burns, Harold A. Heitzmann, Kenneth Martin Curry, David S. Haffner, David Applegate, Bruce Nogales
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Patent number: 11350848Abstract: Systems and methods provide for assessing the heart failure status of a patient and, more particularly, to generating a trend parameter based on a distribution of the patient's respiration rate. Systems and methods provide for detecting, using an implantable device or a patient-external device, patient respiration and computing a respiration rate based on the detected patient respiration. A distribution of the respiration rate is calculated, and a trend parameter based on the respiration rate distribution is generated. The trend parameter is indicative of a patient's heart failure status. An output signal indicative of the patient's heart failure status may be generated based on the trend parameter.Type: GrantFiled: February 11, 2013Date of Patent: June 7, 2022Assignee: Cardiac Pacemakers, Inc.Inventors: Viktoria Averina, Yi Zhang, Yousufali Dalal
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Patent number: 11298074Abstract: A method and system of determining a sleep stage of a user involves receiving a respiratory flow signal of a user, obtaining at least one respiratory feature from at least part of the respiratory flow signal, and determining a sleep stage from the at least one respiratory feature.Type: GrantFiled: December 8, 2016Date of Patent: April 12, 2022Assignee: Fisher & Paykel Healthcare LimitedInventors: Simei Gomes Wysoski, David Robin Whiting
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Patent number: 11291763Abstract: An apparatus comprising a user interface configured to generate an electrical signal to start a basal insulin rate test when prompted by a user, an input configured to receive sampled blood glucose data of a patient that is obtained during a specified time duration, including a time duration during delivery of insulin according to a specified basal insulin rate pattern, and a controller communicatively coupled to the input and the user interface. The controller includes an insulin calculation module configured for determining at least one of an amount of basal insulin over-delivered and an amount of basal insulin under-delivered during the basal insulin rate test in trying to meet a target blood glucose baseline. Other devices and methods are disclosed.Type: GrantFiled: September 15, 2016Date of Patent: April 5, 2022Assignee: Tandem Diabetes Care, Inc.Inventors: Michael L. Blomquist, Thomas Alan Savard
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Patent number: 11234655Abstract: A perfusion trend indicator inputs a plethysmograph waveform having pulses corresponding to pulsatile blood flow within a tissue site. Perfusion values are derived corresponding to the pulses. Time windows are defined corresponding to the perfusion values. Representative perfusion values are defined corresponding to the time windows. A perfusion trend is calculated according to differences between representative perfusion values of adjacent ones of the time windows.Type: GrantFiled: February 14, 2014Date of Patent: February 1, 2022Assignee: Masimo CorporationInventor: Ammar Al-Ali
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Patent number: 11219390Abstract: A device for introducing at least one antimicrobial in an exposed region of a user's skin caused while accessing interstitial fluid includes a substrate having thereon at least one electrically controllable microheating element including at least a microheater portion with multiple electrodes connected to the microheater portion for forming a micropore in the user's skin. A nanofiber mat loaded with at least one antimicrobial material is arranged on the substrate such that it contacts the user's skin and encircles an opening of the micropore formed by the microheating element. In a preferred embodiment, the at least one antimicrobial material is LL-37.Type: GrantFiled: August 2, 2016Date of Patent: January 11, 2022Assignee: Georgetown UniversityInventors: Makarand Paranjape, Shruti M. Paranjape
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Patent number: 11223164Abstract: The invention relates to a plug-in module for a sensor (32) comprising a sleeve-like housing (3) in which a sensor element (27), a carrier board (16) carrying an electronic circuit and a plug-in unit (2) are positioned. In a plug-in module which can be used equally for sensors of different sizes, an outer diameter (5) of the plug-in unit (2) approximately corresponds to a smallest inner diameter (8) of the sleeve-like housing (3), wherein a coding sleeve (4) is inserted between the plug-in unit (2) and the sleeve-like housing (3).Type: GrantFiled: February 26, 2016Date of Patent: January 11, 2022Assignee: SICK AGInventors: Frank Gutmann, Wolfgang Marschner, Dominik Paul
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Patent number: 11213226Abstract: Methods and devices for providing application specific integrated circuit architecture for a two electrode analyte sensor or a three electrode analyte sensor are provided. Systems and kits employing the same are also provided.Type: GrantFiled: October 6, 2011Date of Patent: January 4, 2022Assignee: ABBOTT DIABETES CARE INC.Inventors: Martin J. Fennell, Jean-Pierre Cole, Theodore John Kunich, Udo Hoss, Benjamin Jay Feldman, Zenghe Liu
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Patent number: 11202584Abstract: A gait aid is to be disposed on a shoe, and includes a detecting module, a control circuit and a projecting module. The detecting module generates a sense output based on pressure exerted on a sole of the shoe. The control circuit generates a control signal based at least on the sense output generated by the detecting module. The projecting module is electrically coupled to the control circuit for receiving the control signal therefrom, and is operable, based on the control signal, to project or not to project a cueing mark.Type: GrantFiled: August 4, 2017Date of Patent: December 21, 2021Assignee: Chang Gung UniversityInventor: Ya-Ju Chang