Patents Examined by Katherine Zalasky
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Patent number: 10751698Abstract: The present invention concerns a method of purifying a biological liquid comprising antibodies corresponding to whole human or animal blood or to a product obtained from human or animal blood, by bringing a biological liquid into contact with at least one substrate comprising a solid phase onto which molecules of at least one oligosaccharide are grafted by covalent bonding, the molecules of the at least one oligosaccharide being capable of binding to one or more of said antibodies present in said biological liquid, in a manner such as to capture at least a portion of said antibodies present in said biological liquid by binding with at least certain of the molecules of oligosaccharide(s) grafted onto said solid phase, characterized in that said solid phase carries free aldehyde functions —CHO.Type: GrantFiled: May 3, 2016Date of Patent: August 25, 2020Assignees: ELICITYL, RESEARCH FOUNDATION FOR MEDICAL DEVICESInventors: Ludovic Bastide, Silvère Bonnet, Benoît Darblade, Stéphane Havet, Bernard Mandrand, Mialy Randriantsoa, Jean-Philippe Zeris
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Patent number: 10751688Abstract: A method is described for preparing a sorbent comprising the steps of: (i) forming agglomerates comprising a particulate support material, (ii) coating the agglomerates with a coating mixture powder comprising a particulate copper sulphide and a particulate calcined, rehydratable alumina to form a coated agglomerate, and (iii) drying the coated agglomerate to form a dried sorbent.Type: GrantFiled: May 5, 2016Date of Patent: August 25, 2020Assignee: Johnson Matthey Public Limited CompanyInventors: Matthew James Evans, Matthew David Gwydion Lunn, Martin Graham Partridge, Christopher John Young
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Patent number: 10751686Abstract: A method is described for preparing a sorbent comprising the steps of: (i) mixing together a particulate copper sulphide material and a particulate calcined rehydratable alumina, (ii) shaping the mixture, and (iii) drying the shaped mixture to form a dried sorbent.Type: GrantFiled: May 5, 2016Date of Patent: August 25, 2020Assignee: Johnson Matthey Public Limited CompanyInventors: Matthew James Evans, Matthew David Gwydion Lunn, Martin Graham Partridge, Christopher John Young
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Patent number: 10683223Abstract: A process to remove transition metals from waste water. The process includes the steps of passing waste water to a first pH resin bed, monitoring the effluent from the first resin bed, and adjusting pH to greater than 4. The effluent is passed to a first stage liquid tank and to a first brackish water membrane to filter out complex metals. Rejected effluent from the first brackish water membrane is passed to a second stage liquid tank and thereafter to a second brackish water membrane. The permeate from the second brackish water membrane is passed back to the first stage liquid tank. The rejected effluent from the second brackish water membrane is heated and evaporated. The evaporated effluent is condensed so that metal crystals are gathered for disposal. The permeate through the first brackish membrane is passed to an EDTA resin bed to sequester metal ions. The pH of the discharge from the second pH resin bed is adjusted to between 7 and 11.Type: GrantFiled: March 29, 2017Date of Patent: June 16, 2020Inventor: Paul C. Wegner
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Patent number: 10620125Abstract: A hand-held microfluidic testing device is provided that includes a housing having a cartridge receiving port, a cartridge for input to the cartridge receiving port having a sample input and a channel, where the channel includes a mixture of Raman-scattering nanoparticles and a calibration solution, where the calibration solution includes chemical compounds capable of interacting with a sample under test input to the cartridge and the Raman-scattering nanoparticles, and an optical detection system in the housing, where the optical detection system is capable of providing an illuminated electric field, where the illuminating electric field is capable of being used for Raman spectroscopy with the Raman-scattering nanoparticles and the calibration solution to analyze the sample under test input to the cartridge.Type: GrantFiled: October 24, 2017Date of Patent: April 14, 2020Assignee: ONDAVIA, INC.Inventors: Mark C. Peterman, Merwan Benhabib, Samuel Kleinman
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Patent number: 10611238Abstract: Techniques for separating a fuel on-board a vehicle include mixing an input fuel stream and a fluid solvent; separating the mixture into a first liquid fuel stream and a second liquid fuel stream, the first liquid fuel stream including a first portion of the input fuel stream defined by a first auto-ignition characteristic value and the fluid solvent, the second liquid fuel stream including a second portion of the input fuel stream defined by a second auto-ignition characteristic value that is different than the first auto-ignition characteristic value; separating the first liquid fuel stream into the fluid solvent and the first portion of the input fuel stream; directing the first portion of the input fuel stream to a first fuel tank on the vehicle; and directing the second portion of the input fuel stream to a second fuel tank on the vehicle.Type: GrantFiled: August 16, 2017Date of Patent: April 7, 2020Assignee: Saudi Arabian Oil CompanyInventors: Esam Z. Hamad, Abdullah Sadek AlRamadan
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Patent number: 10603604Abstract: A slurry chamber is fastened to and held in coaxial alignment with a chromatography column by a V-band. One end of the column has an end cap and frit. A slurry of fluid and chromatographic media is placed in the column and chamber. A piston is forced through the chamber and into the column by a hydraulic ram to expel the fluid and form a media bed in the column. The slurry chamber is removed, and a split end cap is fastened to the column. A threaded recess in the split end cap receives a split, threaded collet. The collet is tightened until it pushes against the piston with the same force as the ram, at which point the ram is released and the column removed for use.Type: GrantFiled: July 19, 2017Date of Patent: March 31, 2020Assignee: Phenomenex, Inc.Inventors: Peter C. Rahn, Romaine R. Maiefski, Tivadar Farkas, Emmet E. Welch
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Patent number: 10597751Abstract: Presented herein is a ligand-assisted elution chromatography process for the separation of metal ions using a sorbent. In particular, the present invention discloses a process of two sets of column system in combination with two sets of eluting ligand solutions to prepare substantially pure rare earth elements, wherein the first set of column comprises strong acid cation exchange resins and the second set of chromatographic columns comprises hydrous polyvalent metal oxide selected from the group consisting of TiO2, ZrO2, or SnO2 and wherein ligand of said second ligand solution coordinates with said hydrous polyvalent metal oxide.Type: GrantFiled: July 17, 2015Date of Patent: March 24, 2020Assignee: Purdue Research FoundationInventors: Nien-Hwa Linda Wang, Lei Ling
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Patent number: 10576453Abstract: Methods for fabricating a membrane with an organosilica material which is a polymer comprising independent units of Formula [Z3Z4SiCH2]3 (I), wherein each Z3 represents a hydroxyl group, a C1-C4 alkoxy group or an oxygen atom bonded to a silicon atom of another unit or an active site on the support and each Z4 represents a hydroxyl group, a C1-C4 alkoxy group, a C1-C4 alkyl group, an oxygen atom bonded to a silicon atom of another unit or an active site on the support are provided. Methods of removing a contaminant from a hydrocarbon stream are also provided.Type: GrantFiled: December 11, 2015Date of Patent: March 3, 2020Assignee: EXXONMOBIL RESEARCH AND ENGINEERING COMPANYInventors: Quanchang Li, Dhaval Ajit Bhandari, Benjamin A. McCool
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Patent number: 10549255Abstract: Methods, compositions, devices and kits having a novel chromatographic material are provided herein for separating and identifying organic molecules and compounds, for example molecules and compounds containing electron rich functional groups such as carbon-carbon double bonds. The methods, compositions, and kits include a metal-thiolate chromatographic medium (MTCM) with a sulfur-containing functional group or a metal-selenolate chromatographic medium (MSCM) comprising a selenium-containing functional group covalently attached to a support medium, such that the sulfur-containing functional group or selenium-containing functional group is bound to at least one metal atom. The MTCM and/or MSCM has affinity and specificity to compounds having one or more carbon-carbon double bonds, and performs a highly efficient and rapid separation of samples yielding non-overlapping peaks of purified materials compared to traditional media.Type: GrantFiled: February 6, 2013Date of Patent: February 4, 2020Assignee: BROWN UNIVERSITYInventors: Yongsong Huang, Jose C. Aponte, Rafael Tarozo, James Dillon
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Patent number: 10525419Abstract: An oil-water separation membrane is described. The oil-water separation membrane comprises a porous metal sheet with a photocatalyst layer on one side and a layer of nanoparticles and a surfactant on the other side. The layer of nanoparticles and surfactant create a superoleophobic and superhydrophilic coating that allows passage of an aqueous phase and rejection of an oil phase. The photocatalyst layer, combined with UV irradiation, enables degradation of organic contaminants in the aqueous phase. The oil-water separation membrane may be used as part of an oil-water separation system, and a filtered water product may be recycled through the membrane to increase the removal of organic contaminants.Type: GrantFiled: October 26, 2017Date of Patent: January 7, 2020Assignees: King Fahd University of Petroleum and Minerals, MASSACHUSETTS INSTITUTE OF TECHNOLOGYInventors: Talal F. Qahtan, Leonardo D. Banchik, Mohammed A. Gondal, Gibum Kwon, Divya Panchanathan, Umair Baig, Gareth McKinley, Mohamed A. Dastageer
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Patent number: 10512892Abstract: A process for preparing hollow particles of aluminosilicates having a spherical shape of allophane type which are hybrid at the core, comprising: (a) having, at ambient temperature, an aqueous medium containing at least one aluminum precursor and one silicon alkoxide in an Al/Si molar ratio varying from 1 to 3, (b) carrying out, with stirring, the alkaline hydrolysis of said medium with gradual addition of at least one base in a base/Al molar ratio of 2.3 to 3, (c) maintaining, on conclusion of the addition of all of said base, stirring at ambient temperature until said medium is obtained in the clear state, and (d) heating the solution obtained at a temperature varying from 50 to 150° C. for 2 to 8 days, the combined stages (a) to (d) are carried out within a reactor consisting of a material which is chemically inert with respect to the reactants and expected aluminosilicate.Type: GrantFiled: July 2, 2015Date of Patent: December 24, 2019Assignee: COMMISSARIAT À{grave over ( )} L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVESInventors: Olivier Poncelet, Antoine Thill
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Patent number: 10507431Abstract: A method of cleaning a membrane surface immersed in a liquid medium with a fluid flow, including the steps of providing a randomly generated intermittent or pulsed fluid flow along the membrane surface to dislodge fouling materials therefrom. A membrane module is also disclosed comprising a plurality of porous membranes (6) or a set of membrane modules (5) and a device (11) for providing a generally randomly generated, pulsed fluid flow such that, in use, said fluid flow moves past the surfaces of said membranes (6) to dislodge fouling materials therefrom.Type: GrantFiled: January 10, 2017Date of Patent: December 17, 2019Inventors: Fufang Zha, Gerin James, Joseph Edward Zuback, Peter Zauner, Roger William Phelps
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Patent number: 10501721Abstract: Algae harvesting and cultivating systems and methods for producing high concentrations of algae product with minimal energy. In an embodiment, a dead-end filtration system and method includes at least one tank and a plurality hollow fiber membranes positioned in the at least one tank. An algae medium is pulled through the hollow fiber membranes such that a retentate and a permeate are produced.Type: GrantFiled: September 22, 2016Date of Patent: December 10, 2019Assignee: Global Algae Technologies, LLCInventors: David A. Hazlebeck, William Rickman, Rodney Corpuz
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Patent number: 10494449Abstract: Polydisperse and charged polysaccharides are fractionated into low polydispersity fractions (preferably having pd<1.1), each containing species within a narrow range of molecular weights. An aqueous solution of the polydisperse polysaccharides is contacted with an ion exchange resin in a column and the polysaccharides are subjected to selective elution by aqueous elution buffer. The selective elution consists of at least 3 sequential elution buffers having different and constant ionic strength and/or pH and in which the subsequent buffers have ionic strength and/or pH than those of the preceding step. The new preparations are particularly suitable for the production of PSA-derivatised therapeutic agents intended for use in humans and animals.Type: GrantFiled: November 22, 2017Date of Patent: December 3, 2019Assignee: Lipoxen Technologies LimitedInventors: Sanjay Jain, Ioannis Papaioannou, Peter Laing
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Patent number: 10471393Abstract: A gas sparger produces an intermittent flow of bubbles even if provided with a continuous gas flow. The sparger has a housing to collect a pocket of gas and a conduit to release some of the gas from the pocket when the pocket reaches a sufficient size. Optionally, a cover over an outlet from the conduit may break up or distribute the released gas. A large sparger for use with a commercial membrane module can comprise a plurality of smaller units.Type: GrantFiled: May 17, 2016Date of Patent: November 12, 2019Assignee: BL TECHNOLOGIES, INC.Inventors: Jeffrey Ronald Cumin, Henry Behmann, Yongseck Hong, Reid Bayly
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Patent number: 10449517Abstract: Chromatography media including a high surface area thermoplastic porous nanofiber and an ion-exchange ligand functionality on the surface of the fiber. The porous nanofibers display a convoluted structure that is comprised of discrete bundles of highly entangled nanofibrils that may be fibrillated or ridged. The porous fibers can be prepared through the extraction of a dissolvable mineral or polymeric porogen that is embedded into the fiber during its manufacture in a melt extrusion process.Type: GrantFiled: August 19, 2015Date of Patent: October 22, 2019Assignee: EMD Millipore CorporationInventors: John Paul Amara, John Boyle, David Yavorsky, Benjamin Cacace
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Patent number: 10451592Abstract: An arrangement for preparing samples and analyzing pesticides in samples contains an HILIC chromatography column with a first pump for a predominately low-water and/or non-polar solvent; and SPE enrichment arrangement; a second chromatography column with a second pump for a predominantly water-rich and/or polar solvent; a detector; and a valve arrangement for controlling the stream of sample and matrix, which valve arrangement is designed in such a way that the sample stream, in a first switching state of the valve arrangement, can be conducted from the HILIC chromatography column to the SPE enrichment arrangement and, in a second switching state, the sample enriched in the SPE enrichment arrangement can be conducted in the opposite direction from the SPE enrichment arrangement through the second chromatography column to the detector.Type: GrantFiled: January 30, 2013Date of Patent: October 22, 2019Assignee: Joint Analytical Systems GmbHInventors: Stefan Kittlaus, Jorg Radtke
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Patent number: 10427076Abstract: A method for removing diatomaceous earth and contaminants from a filter, and for filtering liquid using diatomaceous earth is provided. Embodiments of the method can include a washdown process, a backwash process, and a filtering process. Some embodiments can include one or more filter cartridges with cartridge tubes to increase flow during the backwash process. Some embodiments can also include a backwash sprayer to disturb contaminants during the backwash process.Type: GrantFiled: March 5, 2015Date of Patent: October 1, 2019Assignee: Pentair Water Pool and Spa, Inc.Inventors: Robert Frank Swindell, Leonard Richiuso, Brian Everett Cox
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Patent number: 10401334Abstract: The present invention aims at reducing the time required for a series of analyses in the sequential performance of gradient analyses under a variety of conditions. To this end, in a control apparatus for controlling the operation of a liquid chromatograph having a gradient analysis function in which a mobile phase composed of a plurality of mixed solvents is used and a chromatograph analysis is performed while the mixture ratio of the solvents is temporally changed, the liquid chromatograph is controlled so as to continuously change the mixture ratio of the solvents from an initial mixture ratio to a final mixture ratio when performing a sample analysis; and as to perform, before the sample analysis, a preparatory liquid supply in which the mixture ratio of the solvents is continuously changed from the initial mixture ratio to the final mixture ratio at a rate higher than that in the sample analysis.Type: GrantFiled: July 16, 2012Date of Patent: September 3, 2019Assignee: SHIMADZU CORPORATIONInventors: Hiroshi Ohashi, Tadayuki Yamaguchi, Hidetoshi Terada